Affiliation: University of Munich
- Airway surface liquid contains endogenous DNase activity which can be activated by exogenous magnesiumJoseph Rosenecker
Department of Pediatrics, University of Munich, Lindwurmstr 2a, 80337 Munich, Germany
Eur J Med Res 14:304-8. 2009..Little is known about endogenous DNase activity in the airway surface liquid. Therefore, we analysed bronchoalveolar lavage fluid (BAL) and exhaled breath condensate (EBC) for the presence of endogenous DNase activity...
- Characterization of Ku70(2)-NLS as bipartite nuclear localization sequence for non-viral gene deliveryJohannes Matschke
Department of Pediatrics, Ludwig Maximilians University, Munich, Germany
PLoS ONE 7:e24615. 2012..This study shows for the first time that the use of bipartite NLS compounds alone or in combination with cationic polymers is a promising strategy to enhance the efficiency of non-viral gene transfer...
- Gene therapy for cystic fibrosis lung disease: current status and future perspectivesJosef Rosenecker
Department of Pediatrics, Ludwig Maximilians Universitat Munchen, Lindwurmstr 4, D 80337 München, Germany
Curr Opin Mol Ther 8:439-45. 2006..This review outlines the current repertoire of available gene vectors and discusses novel strategies to enhance the efficiency and selectivity of gene transfer for gene delivery into the lung...