Oliver Pogarell

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint Simultaneous EEG-fMRI: perspectives in psychiatry
    Christoph Mulert
    Department of Psychiatry, University of Munich, Germany
    Clin EEG Neurosci 39:61-4. 2008
  2. ncbi request reprint Hand-motor dysfunction in depression: characteristics and pharmacological effects
    Roland Mergl
    Dept of Psychiatry, University Leipzig, Germany
    Clin EEG Neurosci 38:82-8. 2007
  3. ncbi request reprint Clinical neurophysiology services in psychiatry departments
    Oliver Pogarell
    Division of Neurophysiology, Department of Psychiatry at the University of Munich, Germany oliver
    Psychiatr Serv 56:871. 2005
  4. ncbi request reprint Event-related potentials in psychiatry
    Oliver Pogarell
    Department of Psychiatry, Division of Clinical Neurophysiology, Ludwig Maximilians University of Munich, Germany
    Clin EEG Neurosci 38:25-34. 2007
  5. ncbi request reprint Electrophysiological evidence for cortical abnormalities in obsessive-compulsive disorder - a replication study using auditory event-related P300 subcomponents
    Doris Gohle
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    J Psychiatr Res 42:297-303. 2008
  6. ncbi request reprint Auditory cortex and anterior cingulate cortex sources of the early evoked gamma-band response: relationship to task difficulty and mental effort
    Christoph Mulert
    Department of Psychiatry, LMU, Nussbaumstrasse 7, D 80336 Munich, Germany
    Neuropsychologia 45:2294-306. 2007
  7. ncbi request reprint Prediction of clinical response to antidepressants in patients with depression: neurophysiology in clinical practice
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Clin EEG Neurosci 38:74-7. 2007
  8. ncbi request reprint Rostral anterior cingulate cortex activity in the theta band predicts response to antidepressive medication
    Christoph Mulert
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Clin EEG Neurosci 38:78-81. 2007
  9. ncbi request reprint Loudness dependence of auditory evoked potentials is not associated with polymorphisms or haplotypes in the serotonin transporter gene in a community-based sample of German healthy volunteers
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, Germany
    Psychiatry Res 153:183-7. 2007
  10. pmc [I-123] ADAM and SPECT in patients with borderline personality disorder and healthy control subjects
    Walter Koch
    Department of Nuclear Medicine, Ludwig Maximilians University, Munich, Germany
    J Psychiatry Neurosci 32:234-40. 2007

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Simultaneous EEG-fMRI: perspectives in psychiatry
    Christoph Mulert
    Department of Psychiatry, University of Munich, Germany
    Clin EEG Neurosci 39:61-4. 2008
    ..EEG-fMRI may prove to be crucial in providing much deeper understanding of brain activity over the next decades. This review summarizes the basic physiology, methodological issues and interesting applications in psychiatry...
  2. ncbi request reprint Hand-motor dysfunction in depression: characteristics and pharmacological effects
    Roland Mergl
    Dept of Psychiatry, University Leipzig, Germany
    Clin EEG Neurosci 38:82-8. 2007
    ..II: Computer-aided analysis of hand movements is a sensitive tool for the registration of differential pharmaceutical effects on hand-motor function in depression...
  3. ncbi request reprint Clinical neurophysiology services in psychiatry departments
    Oliver Pogarell
    Division of Neurophysiology, Department of Psychiatry at the University of Munich, Germany oliver
    Psychiatr Serv 56:871. 2005
  4. ncbi request reprint Event-related potentials in psychiatry
    Oliver Pogarell
    Department of Psychiatry, Division of Clinical Neurophysiology, Ludwig Maximilians University of Munich, Germany
    Clin EEG Neurosci 38:25-34. 2007
    ..Among these techniques, event-related potentials (ERPs) are of major interest in psychiatry, particularly since these tools can indicate cortical neuronal dysfunctions, which play a major role in various neuropsychiatric disorders...
  5. ncbi request reprint Electrophysiological evidence for cortical abnormalities in obsessive-compulsive disorder - a replication study using auditory event-related P300 subcomponents
    Doris Gohle
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    J Psychiatr Res 42:297-303. 2008
    ..Once again, our findings point to a hyperactivated cortical state also of temporo-parietal and hippocampal regions in OCD...
  6. ncbi request reprint Auditory cortex and anterior cingulate cortex sources of the early evoked gamma-band response: relationship to task difficulty and mental effort
    Christoph Mulert
    Department of Psychiatry, LMU, Nussbaumstrasse 7, D 80336 Munich, Germany
    Neuropsychologia 45:2294-306. 2007
    ..These findings are in line with a top-down influence of dACC-activity to the auditory association area 22 during the early evoked GBR...
  7. ncbi request reprint Prediction of clinical response to antidepressants in patients with depression: neurophysiology in clinical practice
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Clin EEG Neurosci 38:74-7. 2007
    ..This review focuses on recent studies providing evidence for the validity of LD as an indirect serotonergic marker and highlights data on the clinical application in terms of prediction of treatment response in patients with depression...
  8. ncbi request reprint Rostral anterior cingulate cortex activity in the theta band predicts response to antidepressive medication
    Christoph Mulert
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Clin EEG Neurosci 38:78-81. 2007
    ..In addition to major differences between responders and nonresponders in the rostral ACC, we have identified a nearby region in the midline orbito-frontal region...
  9. ncbi request reprint Loudness dependence of auditory evoked potentials is not associated with polymorphisms or haplotypes in the serotonin transporter gene in a community-based sample of German healthy volunteers
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, Germany
    Psychiatry Res 153:183-7. 2007
    ..We speculate that the LD endophenotype depends more on genetic variations in components of the serotonergic system controlling release than on those controlling the uptake mechanism...
  10. pmc [I-123] ADAM and SPECT in patients with borderline personality disorder and healthy control subjects
    Walter Koch
    Department of Nuclear Medicine, Ludwig Maximilians University, Munich, Germany
    J Psychiatry Neurosci 32:234-40. 2007
    ..The aim of this study was to investigate serotonin transporter availability in patients with BPD as a marker of the central serotonergic system...
  11. ncbi request reprint Influence of trait anxiety on inhibitory control in alcohol-dependent patients: simultaneous acquisition of ERPs and BOLD responses
    Susanne Karch
    Department of Psychiatry, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, D 80336 Munich, Germany
    J Psychiatr Res 42:734-45. 2008
    ..This may indicate that comorbid psychiatric symptoms need to be considered when assessing brain responses in alcohol-dependent patients...
  12. ncbi request reprint Differential prediction of first clinical response to serotonergic and noradrenergic antidepressants using the loudness dependence of auditory evoked potentials in patients with major depressive disorder
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, Bochum, Germany
    J Clin Psychiatry 68:1206-12. 2007
    ..The aim of the current randomized prospective study was to investigate whether or not LDAEP also allows the differential prediction of treatment response to serotonergic versus noradrenergic antidepressants...
  13. ncbi request reprint Association of 5-HT1B receptor polymorphisms with the loudness dependence of auditory evoked potentials in a community-based sample of healthy volunteers
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, Alexandrinenstrasse 1, 44791 Bochum, Germany
    Am J Med Genet B Neuropsychiatr Genet 147:454-8. 2008
    ....
  14. ncbi request reprint [123I] ADAM brainstem binding correlates with the loudness dependence of auditory evoked potentials
    Oliver Pogarell
    Dept of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 258:40-7. 2008
    ..01). Associations between LD and SERT availability contribute to the understanding of the central serotonergic system and further validate the use of neurophysiological approaches as indirect measures of neurochemical brain activity...
  15. doi request reprint Diagnostic usefulness of cognitive auditory event-related p300 subcomponents in patients with Alzheimers disease?
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, Germany
    J Clin Neurophysiol 25:147-52. 2008
    ....
  16. ncbi request reprint Association of catechol-O-methyltransferase variants with loudness dependence of auditory evoked potentials
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, Germany
    Hum Psychopharmacol 23:115-20. 2008
    ..The aim of this study was to investigate the relationship between genetic variants of the COMT gene influencing synaptic dopamine levels and the LDAEP...
  17. ncbi request reprint Loudness dependence of the auditory evoked N1/P2 component as an indicator of serotonergic dysfunction in patients with schizophrenia--a replication study
    Georg Juckel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Germany
    Psychiatry Res 158:79-82. 2008
    ..Thus, we were able again to demonstrate electrophysiological evidence for an upregulated serotonergic system in schizophrenia...
  18. doi request reprint Association of functional polymorphisms in NOS1 and NOS3 with loudness dependence of auditory evoked potentials
    Wolfram Kawohl
    Research Group Clinical and Experimental Psychopathology, Psychiatric University Hospital Zurich, Zurich, Switzerland
    Int J Neuropsychopharmacol 11:477-83. 2008
    ..Further studies are needed to fully clarify the relationship between nitrinergic transmission, LDAEP and complex disorders such as schizophrenia and affective disorders...
  19. ncbi request reprint Extended studies of the striatal uptake of 99mTc-NC100697 in healthy volunteers
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Munich, Germany
    J Nucl Med 48:27-34. 2007
    ..This study evaluates a new formulation of a (99m)Tc-labeled tropane derivate, (99m)Tc-NC100697, in a human volunteer study...
  20. ncbi request reprint Prediction of treatment response in major depression: integration of concepts
    Christoph Mulert
    Department of Psychiatry, LMU, Munich, Germany
    J Affect Disord 98:215-25. 2007
    ..Here, a high LDAEP is supposed to reflect low central serotonergic activity. We present the first study comparing both approaches in the same group of patients...
  21. ncbi request reprint Event related potentials and fMRI in neuropsychopharmacology
    Oliver Pogarell
    Department of Psychiatry, Division of Clinical Neurophysiology, Ludwig Maximilians University of Munich, Munich, Germany
    Clin EEG Neurosci 37:99-107. 2006
    ..Owing to important recent developments in the field of brain functional diagnostics the combination of neurophysiological techniques and functional magnetic resonance imaging (fMRI) will be included...
  22. ncbi request reprint Differential effects of reboxetine and citalopram on hand-motor function in patients suffering from major depression
    Ulrich Hegerl
    Laboratory of Clinical Neurophysiology, Department of Psychiatry, Ludwig Maximilians Universitat Munchen, Nussbaumstr 7, 80336, Munich, Germany
    Psychopharmacology (Berl) 178:58-66. 2005
    ..However, the effects of antidepressants on motor function in depression have rarely been analyzed systematically. Computerized methods allow the objective registration of drug-induced motor dysfunction and were applied in this study...
  23. ncbi request reprint Serotonin and dopamine transporter availabilities correlate with the loudness dependence of auditory evoked potentials in patients with obsessive-compulsive disorder
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Neuropsychopharmacology 29:1910-7. 2004
    ....
  24. ncbi request reprint Integration of fMRI and simultaneous EEG: towards a comprehensive understanding of localization and time-course of brain activity in target detection
    Christoph Mulert
    Department of Psychiatry, LMU, Nussbaumstrasse 7, 80336 Munich, Germany
    Neuroimage 22:83-94. 2004
    ..The results suggest that the combination of EEG and fMRI permits an improved understanding of the spatiotemporal dynamics of brain activity...
  25. ncbi request reprint EEG abnormalities associated with antipsychotics: a comparison of quetiapine, olanzapine, haloperidol and healthy subjects
    Benedikt L Amann
    Department of Psychiatry, Section of Clinical Neurophysiology, University of Munich, Germany
    Hum Psychopharmacol 18:641-6. 2003
    ..To our knowledge, this is the first electrophysiological investigation comparing the new atypical antipsychotics quetiapine, haloperidol, olanzapine with healthy subjects...
  26. ncbi request reprint Elevated brain serotonin transporter availability in patients with obsessive-compulsive disorder
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 54:1406-13. 2003
    ..The aim of this study was to investigate the serotonin transporter availability in patients with OCD as an in vivo marker of the central serotonergic system...
  27. ncbi request reprint Prospective study of presynaptic dopaminergic imaging in patients with mild parkinsonism and tremor disorders: part 1. Baseline and 3-month observations
    Hani T S Benamer
    Neurology Department, New Cross Hospital, Wolverhampton, United Kingdom
    Mov Disord 18:977-84. 2003
    ..When these clinical features are uncertain, or the patient fails clinical diagnostic criteria, testing for dopaminergic deficit with [(123)I]-FP-CIT SPECT may assist the diagnostic process...
  28. ncbi request reprint Epileptiform EEG patterns induced by mirtazapine in both psychiatric patients and healthy volunteers
    Georg Juckel
    J Clin Psychopharmacol 23:421-2. 2003
  29. ncbi request reprint Kinematic analysis of the effects of donepezil hydrochloride on hand motor function in patients with Alzheimer dementia
    Ulrich Hegerl
    J Clin Psychopharmacol 23:214-6. 2003
  30. ncbi request reprint Loss of dopamine transporter binding in Parkinson's disease follows a single exponential rather than linear decline
    Johannes Schwarz
    Department of Neurology, University of Leipzig, Leipzig, Germany
    J Nucl Med 45:1694-7. 2004
    ..Most follow-up studies have provided data best fitted by a linear decline of their outcome measure. However, in these studies, patients were repeatedly scanned during their first years after a diagnosis had been established...
  31. ncbi request reprint Evidence for a close relationship between conscious effort and anterior cingulate cortex activity
    Christoph Mulert
    Department of Psychiatry, Nussbaumstrasse 7, LMU, Munich 80336 München, Germany
    Int J Psychophysiol 56:65-80. 2005
    ..These results provide direct evidence for a close relationship between conscious effort and ACC activity and suggest the usefulness of the applied effort-self-rating...
  32. ncbi request reprint Sound level dependence of the primary auditory cortex: Simultaneous measurement with 61-channel EEG and fMRI
    Christoph Mulert
    Department of Psychiatry, LMU, Munich, Germany
    Neuroimage 28:49-58. 2005
    ..In addition, the correspondence of the ERP-based data and the fMRI results further supports the validity of the ERP localization approach...
  33. ncbi request reprint Electroencephalographic abnormalities associated with antidepressant treatment: a comparison of mirtazapine, venlafaxine, citalopram, reboxetine, and amitriptyline
    Andrea Sterr
    J Clin Psychiatry 67:325-6. 2006
  34. ncbi request reprint Symptom-specific EEG power correlations in patients with obsessive-compulsive disorder
    Oliver Pogarell
    Department of Psychiatry, Division of Clinical Neurophysiology, Ludwig Maximilians University of Munich, Germany
    Int J Psychophysiol 62:87-92. 2006
    ..The opposite correlations of neurophysiological data and clinical features, i.e. obsessions and compulsions, are suggestive of pathophysiological differences based on the presence of the respective cardinal symptoms of OCD...
  35. ncbi request reprint SERT and DAT availabilities under citalopram treatment in obsessive-compulsive disorder (OCD)
    Oliver Pogarell
    Department of Psychiatry, Section of Clinical Neurophysiology, Ludwig Maximilians University of Munich, Nussbaumstr 7, D 80336 Munich, Germany
    Eur Neuropsychopharmacol 15:521-4. 2005
    ..The data point at a citalopram induced modulation of both serotonergic and dopaminergic activity and support the notion of functional interactions of monoaminergic systems in the human brain...
  36. ncbi request reprint A Ser9Gly polymorphism in the dopamine D3 receptor gene (DRD3) and event-related P300 potentials
    Christoph Mulert
    Department of Psychiatry, University of Munich, LMU, Munich, Germany
    Neuropsychopharmacology 31:1335-44. 2006
    ..Further studies should address the direct role of the DRD3 Ser9Gly polymorphism in attenuated P300 amplitudes in psychiatric disorders like schizophrenia or alcoholism...
  37. ncbi request reprint [Neuroimaging and the neurobiology of obsessive-compulsive disorder]
    Günter Schiepek
    Forschungseinrichtung für Dynamische Systeme, Institut fur Psychologie, Alpen Adria Universität Klagenfurt
    Psychother Psychosom Med Psychol 57:379-94. 2007
    ..Deficits in action-monitoring and planning are discussed to be one of the basic dysfunctions of OCD. Finally, results of psychotherapeutic induced variations of brain activations in OCD are presented...
  38. ncbi request reprint Striatal dopamine release after prefrontal repetitive transcranial magnetic stimulation in major depression: preliminary results of a dynamic [123I] IBZM SPECT study
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    J Psychiatr Res 40:307-14. 2006
    ..In future, this approach can be used to differentiate specific and non-specific reward-related effects of rTMS on dopaminergic neurotransmission...
  39. ncbi request reprint EEG-vigilance differences between patients with borderline personality disorder, patients with obsessive-compulsive disorder and healthy controls
    Ulrich Hegerl
    Department of Psychiatry, University of Leipzig, Leipzig, Germany
    Eur Arch Psychiatry Clin Neurosci 258:137-43. 2008
    ....
  40. ncbi request reprint Suicide prevention by lithium SUPLI--challenges of a multi-center prospective study
    Erik Lauterbach
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Schleswig Holstein, Luebeck, Germany
    Arch Suicide Res 9:27-34. 2005
    ..The hypothesis is that lithium treatment will lead to a 50% reduction of suicidal behavior. The protocol of the study and preliminary results are presented...
  41. ncbi request reprint Transcranial and deep brain stimulation approaches as treatment for depression
    Anne Rau
    Dept of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Munich, Germany
    Clin EEG Neurosci 38:105-15. 2007
    ..Also, the methods vary regarding their degree of invasiveness. One or the other method may finally achieve antidepressant effectiveness with minimized side effects and constitute a new effective treatment for major depression...
  42. ncbi request reprint Acute prefrontal rTMS increases striatal dopamine to a similar degree as D-amphetamine
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
    Psychiatry Res 156:251-5. 2007
    ..95% (difference not statistically significant). Acute rTMS challenge showed similar striatal dopaminergic effects to those associated with the administration of d-amphetamine, a substance known to increase synaptic dopamine...