Renato Paro

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. pmc RNA at the steering wheel
    Sabine Schmitt
    Zentrum für Molekulare Biologie Heidelberg ZMBH, University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany
    Genome Biol 7:218. 2006
  2. ncbi request reprint Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila
    Sylvia Erhardt
    ZMBH, University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany
    Dev Genes Evol 213:336-44. 2003
  3. pmc Intergenic transcription through a polycomb group response element counteracts silencing
    Sabine Schmitt
    Zentrum für Molekular Biologie Heidelberg ZMBH, University of Heidelberg, D 69120 Heidelberg, Germany
    Genes Dev 19:697-708. 2005
  4. ncbi request reprint Expression of leukemic MLL fusion proteins in Drosophila affects cell cycle control and chromosome morphology
    Inhua Muyrers-Chen
    ZMBH, University of Heidelberg, D 69120 Heidelberg, Germany
    Oncogene 23:8639-48. 2004
  5. pmc Comparing active and repressed expression states of genes controlled by the Polycomb/Trithorax group proteins
    Christian Beisel
    Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, Im Neuenheimer Feld 282, D 69120 Heidelberg, Germany
    Proc Natl Acad Sci U S A 104:16615-20. 2007
  6. ncbi request reprint Distinct contributions of histone H3 lysine 9 and 27 methylation to locus-specific stability of polycomb complexes
    Leonie Ringrose
    ZMBH, University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany
    Mol Cell 16:641-53. 2004
  7. pmc Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila
    Gunter Merdes
    ZMBH, University of Heidelberg, Heidelberg, Germany
    EMBO J 23:4082-95. 2004
  8. ncbi request reprint Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
    Leonie Ringrose
    ZMBH, University of Heidelberg, 69120 Heidelberg, Germany
    Annu Rev Genet 38:413-43. 2004
  9. pmc Non-coding transcripts in the H19 imprinting control region mediate gene silencing in transgenic Drosophila
    Stefan Schoenfelder
    Zentrum fuer Molekulare Biologie Heidelberg, Universitaet Heidelberg, INF 282, 69120 Heidelberg, Germany
    EMBO Rep 8:1068-73. 2007
  10. pmc Transcription through intergenic chromosomal memory elements of the Drosophila bithorax complex correlates with an epigenetic switch
    Gerhard Rank
    Center for Molecular Biology Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany
    Mol Cell Biol 22:8026-34. 2002

Collaborators

Detail Information

Publications16

  1. pmc RNA at the steering wheel
    Sabine Schmitt
    Zentrum für Molekulare Biologie Heidelberg ZMBH, University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany
    Genome Biol 7:218. 2006
    ....
  2. ncbi request reprint Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila
    Sylvia Erhardt
    ZMBH, University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany
    Dev Genes Evol 213:336-44. 2003
    ..Polycomb group proteins are essential for gene silencing during development. Our results indicate that Polycomb group proteins may also be involved in the regulation of mammalian imprinted genes...
  3. pmc Intergenic transcription through a polycomb group response element counteracts silencing
    Sabine Schmitt
    Zentrum für Molekular Biologie Heidelberg ZMBH, University of Heidelberg, D 69120 Heidelberg, Germany
    Genes Dev 19:697-708. 2005
    ....
  4. ncbi request reprint Expression of leukemic MLL fusion proteins in Drosophila affects cell cycle control and chromosome morphology
    Inhua Muyrers-Chen
    ZMBH, University of Heidelberg, D 69120 Heidelberg, Germany
    Oncogene 23:8639-48. 2004
    ..Taken together, the expression of MLL fusion proteins in Drosophila provides a new and powerful system to reveal and characterize biological activities associated with MLL fusion proteins...
  5. pmc Comparing active and repressed expression states of genes controlled by the Polycomb/Trithorax group proteins
    Christian Beisel
    Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, Im Neuenheimer Feld 282, D 69120 Heidelberg, Germany
    Proc Natl Acad Sci U S A 104:16615-20. 2007
    ..Besides its presumptive function in recruiting PcG complexes to their site of action, our results now uncover that Pho plays an additional role in the repression of already induced genes...
  6. ncbi request reprint Distinct contributions of histone H3 lysine 9 and 27 methylation to locus-specific stability of polycomb complexes
    Leonie Ringrose
    ZMBH, University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany
    Mol Cell 16:641-53. 2004
    ..We use mathematical modeling to examine these data, and propose that weak Polycomb-histone tail interactions enable PcG complexes to bind dynamically to chromatin, offering opportunities for regulation...
  7. pmc Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila
    Gunter Merdes
    ZMBH, University of Heidelberg, Heidelberg, Germany
    EMBO J 23:4082-95. 2004
    ....
  8. ncbi request reprint Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
    Leonie Ringrose
    ZMBH, University of Heidelberg, 69120 Heidelberg, Germany
    Annu Rev Genet 38:413-43. 2004
    ..Here we review current ideas on the protein and DNA components of this transcriptional memory system and how they interact dynamically with each other to orchestrate cellular memory for several hundred genes...
  9. pmc Non-coding transcripts in the H19 imprinting control region mediate gene silencing in transgenic Drosophila
    Stefan Schoenfelder
    Zentrum fuer Molekulare Biologie Heidelberg, Universitaet Heidelberg, INF 282, 69120 Heidelberg, Germany
    EMBO Rep 8:1068-73. 2007
    ....
  10. pmc Transcription through intergenic chromosomal memory elements of the Drosophila bithorax complex correlates with an epigenetic switch
    Gerhard Rank
    Center for Molecular Biology Heidelberg, University of Heidelberg, 69120 Heidelberg, Germany
    Mol Cell Biol 22:8026-34. 2002
    ..Interestingly, in the bithorax complex of D. melanogaster, the segment-specific expression of noncoding intergenic transcripts during embryogenesis seems to fulfill this switching role for memory elements regulating the homeotic genes...
  11. ncbi request reprint Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs
    Nara Lee
    Centre for Molecular Biology Heidelberg ZMBH, University of Heidelberg, 69120 Heidelberg, Germany
    Nature 438:234-7. 2005
    ..This regulatory interaction also occurs in mammalian cells, indicating that the role of this signalling cascade in remodelling cellular fates may be conserved...
  12. ncbi request reprint Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster
    Leonie Ringrose
    ZMBH, Universitat Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany
    Dev Cell 5:759-71. 2003
    ..Using the larger data set thus generated, we identify three sequence motifs that are conserved in PRE/TRE sequences...
  13. pmc Homo- and heterodimerization of APP family members promotes intercellular adhesion
    Peter Soba
    ZMBH, University of Heidelberg, Heidelberg, Germany
    EMBO J 24:3624-34. 2005
    ..Together, our results provide evidence that homo- and heterocomplexes of APP/APLPs promote trans-cellular adhesion in vivo...
  14. pmc A cellular memory module conveys epigenetic inheritance of hedgehog expression during Drosophila wing imaginal disc development
    Cédric Maurange
    Zentrum für Molekulare Biologie Heidelberg ZMBH, University of Heidelberg, D 69120 Heidelberg, Germany
    Genes Dev 16:2672-83. 2002
    ....
  15. pmc Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development
    Alexander Loewer
    ZMBH, University of Heidelberg, INF 282, 69120 Heidelberg, Germany
    EMBO Rep 5:405-11. 2004
    ..Using this system, we demonstrate differences between APP and Notch processing and show that PS-mediated cleavage of APP can be regulated in different cell types independent of the size of the extracellular domain...
  16. pmc DNA hypermethylation in Drosophila melanogaster causes irregular chromosome condensation and dysregulation of epigenetic histone modifications
    Frank Weissmann
    Research Group Epigenetics, Deutsches Krebsforschungszentrum, 69120 Heidelberg, Germany
    Mol Cell Biol 23:2577-86. 2003
    ..Our results thus uncover the molecular consequences of genomic hypermethylation and demonstrate a mutual interaction between DNA methylation and histone methylation...