Hans Jurgen Moller

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. doi request reprint Development of DSM-V and ICD-11: tendencies and potential of new classifications in psychiatry at the current state of knowledge
    Hans Jurgen Moller
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Clin Neurosci 63:595-612. 2009
  2. ncbi request reprint Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
    Arch Gen Psychiatry 61:177-83. 2004
  3. doi request reprint Remission and recovery and their predictors in schizophrenia spectrum disorder: results from a 1-year follow-up naturalistic trial
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Psychiatr Q 83:187-207. 2012
  4. doi request reprint Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment response
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 158:297-305. 2008
  5. doi request reprint Predictors of relapse in the year after hospital discharge among patients with schizophrenia
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstreet 7, 80336 Munich, Germany
    Psychiatr Serv 63:87-90. 2012
  6. doi request reprint Functional connectivity bias of the orbitofrontal cortex in drug-free patients with major depression
    Thomas Frodl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Munich, Germany
    Biol Psychiatry 67:161-7. 2010
  7. doi request reprint Associations of SNAP-25 polymorphisms with cognitive dysfunctions in Caucasian patients with schizophrenia during a brief trail of treatment with atypical antipsychotics
    Ilja Spellmann
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 258:335-44. 2008
  8. doi request reprint Quality of life and subjective well-being in schizophrenia and schizophrenia spectrum disorders: valid predictors of symptomatic response and remission?
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 11:729-38. 2010
  9. ncbi request reprint The influence of concomitant neuroleptic medication on safety, tolerability and clinical effectiveness of electroconvulsive therapy
    Caroline Nothdurfter
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 7:162-70. 2006
  10. ncbi request reprint Striatal dopamine release after prefrontal repetitive transcranial magnetic stimulation in major depression: preliminary results of a dynamic [123I] IBZM SPECT study
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    J Psychiatr Res 40:307-14. 2006

Collaborators

Detail Information

Publications83

  1. doi request reprint Development of DSM-V and ICD-11: tendencies and potential of new classifications in psychiatry at the current state of knowledge
    Hans Jurgen Moller
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Clin Neurosci 63:595-612. 2009
    ..Based on the different aspects that must be considered in this context, a careful revision seems more advisable than a radical change of classification...
  2. ncbi request reprint Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
    Arch Gen Psychiatry 61:177-83. 2004
    ..Several studies have found reciprocal interactions between the serotonergic system and both brain-derived neurotrophic factor and glutamate, which are known to modulate or affect hippocampal morphologic characteristics...
  3. doi request reprint Remission and recovery and their predictors in schizophrenia spectrum disorder: results from a 1-year follow-up naturalistic trial
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Psychiatr Q 83:187-207. 2012
    ..0113) were found to be significantly predictive of recovery. Our results underline the need to implement more specific treatment strategies to improve long-term outcome...
  4. doi request reprint Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment response
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 158:297-305. 2008
    ..Therefore, the hypothesis that depressive symptoms are predictive of a favorable treatment response was not supported by the present study...
  5. doi request reprint Predictors of relapse in the year after hospital discharge among patients with schizophrenia
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstreet 7, 80336 Munich, Germany
    Psychiatr Serv 63:87-90. 2012
    ..Relapse and its predictors were examined among patients with schizophrenia in the year after hospital discharge...
  6. doi request reprint Functional connectivity bias of the orbitofrontal cortex in drug-free patients with major depression
    Thomas Frodl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Munich, Germany
    Biol Psychiatry 67:161-7. 2010
    ..The aim of this study was to compare the functional connectivity of the OFC during emotion processing in patients with major depression and healthy control subjects...
  7. doi request reprint Associations of SNAP-25 polymorphisms with cognitive dysfunctions in Caucasian patients with schizophrenia during a brief trail of treatment with atypical antipsychotics
    Ilja Spellmann
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 258:335-44. 2008
    ....
  8. doi request reprint Quality of life and subjective well-being in schizophrenia and schizophrenia spectrum disorders: valid predictors of symptomatic response and remission?
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 11:729-38. 2010
    ..To examine quality of life and subjective well-being as predictors of symptomatic treatment outcome...
  9. ncbi request reprint The influence of concomitant neuroleptic medication on safety, tolerability and clinical effectiveness of electroconvulsive therapy
    Caroline Nothdurfter
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 7:162-70. 2006
    ..In these cases, concomitant pharmacotherapy can be a useful augmentation strategy to improve clinical effectiveness. Interestingly, there is not much data about ECT and concomitant neuroleptic medication...
  10. ncbi request reprint Striatal dopamine release after prefrontal repetitive transcranial magnetic stimulation in major depression: preliminary results of a dynamic [123I] IBZM SPECT study
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    J Psychiatr Res 40:307-14. 2006
    ..In future, this approach can be used to differentiate specific and non-specific reward-related effects of rTMS on dopaminergic neurotransmission...
  11. ncbi request reprint Elevated brain serotonin transporter availability in patients with obsessive-compulsive disorder
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 54:1406-13. 2003
    ..The aim of this study was to investigate the serotonin transporter availability in patients with OCD as an in vivo marker of the central serotonergic system...
  12. doi request reprint Depressive symptoms and their association with acute treatment outcome in first-episode schizophrenia patients: comparing treatment with risperidone and haloperidol
    Michael Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 13:30-8. 2012
    ..To evaluate depressive symptoms regarding their association with the acute outcome in first-episode schizophrenia comparing risperidone and haloperidol...
  13. doi request reprint Does early improvement in major depression protect against treatment emergent suicidal ideation?
    Florian Seemüller
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, Munich, Germany
    J Affect Disord 124:183-6. 2010
    ..To investigate the association of early improvement and treatment emergent suicidal ideation in a large sample (N=705) of naturalistically treated inpatients with major depressive disorder...
  14. ncbi request reprint Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression
    Thomas Frodl
    Department of Psychiatry and Psychotherapy and Radiology, Ludwig Maximilians University, Munich, Germany
    Arch Gen Psychiatry 64:410-6. 2007
    ..Brain-derived neurotrophic factor (BDNF) modulates hippocampal plasticity, which is believed to be altered in patients with major depression...
  15. ncbi request reprint Amygdala volume and depressive symptoms in patients with borderline personality disorder
    Thomas Zetzsche
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 60:302-10. 2006
    ..The aim of this study was to examine whether a co-occurrence of MD is associated with structural changes in the amygdala of BPD patients...
  16. doi request reprint Multivariate patterns of brain-cognition associations relating to vulnerability and clinical outcome in the at-risk mental states for psychosis
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Munich, Germany
    Hum Brain Mapp 33:2104-24. 2012
    ..However, structure-cognition relationships in the ARMS have not been directly explored using multivariate neuroimaging techniques...
  17. doi request reprint Estrogen receptor gene 1 variants are not associated with suicidal behavior
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 160:1-7. 2008
    ..In conclusion, our study does not support the hypothesis that estrogen receptor alpha gene variants are major contributors to suicide or to anger- or aggression-related behaviors...
  18. ncbi request reprint Prediction of symptom remission in schizophrenia during inpatient treatment
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 10:426-34. 2009
    ..The present study applied the symptom-severity component of these criteria to a sample of inpatients in order to determine the rates of remission during inpatient treatment and to explore predictors of remission...
  19. doi request reprint Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study
    Eva M Meisenzahl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Nussbaumstrasse 7, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 260:127-37. 2010
    ....
  20. pmc Reduced hippocampal volume correlates with executive dysfunctioning in major depression
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
    J Psychiatry Neurosci 31:316-23. 2006
    ..We aimed to investigate whether reduced hippocampal volumes correlate with executive dysfunctioning or memory dysfunctioning or with depression severity...
  21. ncbi request reprint Tachykinin receptor 1 variants associated with aggression in suicidal behavior
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 144:757-61. 2007
    ..In conclusion, our study suggests that TACR1 gene variants have no major influence on suicidal behavior but may modulate aggression features...
  22. doi request reprint Use of neuroanatomical pattern regression to predict the structural brain dynamics of vulnerability and transition to psychosis
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 123:175-87. 2010
    ..To date, it is unknown whether these dynamic brain changes can be predicted at the single-subject level prior to disease transition using MRI-based machine-learning techniques...
  23. doi request reprint Neuroanatomical correlates of executive dysfunction in the at-risk mental state for psychosis
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 123:160-74. 2010
    ....
  24. doi request reprint Anterior cingulum volumetry, auditory P300 in schizophrenia with negative symptoms
    Ulrich W Preuss
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstrasse 7, D 80336 Munich, Germany
    Psychiatry Res 183:133-9. 2010
    ..In addition, while right hemisphere ACC volumes significantly differ between schizophrenia subgroups, combining measures of event-related potential (ERP) and ACC volumetry does not add additional information...
  25. ncbi request reprint Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease
    Harald Hampel
    Alzheimer Memorial Center and Geriatric Psychiatry Branch, Dementia and Neuroimaging Section, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Arch Neurol 62:770-3. 2005
    ..We hypothesized that these variations partially reflect differences in the degree of neuronal damage and therefore may be used to predict structural disease progression...
  26. ncbi request reprint Depression with atypical features in a sample of primary care outpatients: prevalence, specific characteristics and consequences
    Verena Henkel
    Department of Psychiatry, Ludwig Maximilians University Munich, Nussbaumstr 7, D 80336 Munich, Germany
    J Affect Disord 83:237-42. 2004
    ....
  27. ncbi request reprint Anger- and aggression-related traits are associated with polymorphisms in the 5-HT-2A gene
    Ina Giegling
    Molecular and Clinical Neurobiology, Department of Psychiatry, University of Munich, Germany
    J Affect Disord 96:75-81. 2006
    ....
  28. doi request reprint Response trajectories in "real-world" naturalistically treated schizophrenia patients
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 139:218-24. 2012
    ..To date, research has identified distinct antipsychotic response trajectories yet focussing on data from randomized-controlled trials (RCTs). Therefore, the heterogeneity of response in "real-world" schizophrenia patients is still unknown...
  29. doi request reprint Reduced early auditory evoked gamma-band response in patients with schizophrenia
    Gregor Leicht
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, 7D 80336 Munich, Germany
    Biol Psychiatry 67:224-31. 2010
    ..power and phase-locking in schizophrenic patients?; and 2) Is this possible decrease a result of reduced activity in the auditory cortex and/or the anterior cingulate cortex (ACC), which were identified as sources of the GBR previously?..
  30. doi request reprint Attention to emotion: auditory-evoked potentials in an emotional choice reaction task and personality traits as assessed by the NEO FFI
    Verena Mittermeier
    Department of Psychiatry and Psychotherapy, LMU, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 261:111-20. 2011
    ..Interestingly, subjects with high scores in the personality trait extraversion showed significantly higher EPN amplitudes for emotional paradigms (syllables and words) than introverted subjects...
  31. ncbi request reprint Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center, Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    Arch Neurol 59:1267-72. 2002
    ....
  32. doi request reprint Altered brain activation during a verbal working memory task in subjects with amnestic mild cognitive impairment
    Arun L W Bokde
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Alzheimer Memorial Center, Munich, Germany
    J Alzheimers Dis 21:103-18. 2010
    ..The activation differences between groups may be compensatory mechanisms within the MCI group for the effects of the putative AD neuropathology. This has been the first study that has examined verbal working memory in MCI...
  33. ncbi request reprint Dopa decarboxylase and tyrosine hydroxylase gene variants in suicidal behavior
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 147:308-15. 2008
    ..In conclusion, our study does not support the involvement of TH gene variants as major contributors to suicide, whereas DDC variants could mediate some features related to suicide and be involved in violent suicidal behavior...
  34. ncbi request reprint Larger amygdala volumes in first depressive episode as compared to recurrent major depression and healthy control subjects
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 53:338-44. 2003
    ..The aim of our study was to test the hypothesis that amygdala volumes are reduced in patients with recurrent major depression compared with first episode patients...
  35. ncbi request reprint Hippocampal and amygdala changes in patients with major depressive disorder and healthy controls during a 1-year follow-up
    Thomas Frodl
    Department of Psychiatry, Clinical Center Innenstadt, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    J Clin Psychiatry 65:492-9. 2004
    ....
  36. ncbi request reprint A functional single nucleotide polymorphism (V158M) in the COMT gene is associated with aggressive personality traits
    Dan Rujescu
    Department of Psychiatry, Division of Molecular Neurobiology, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 54:34-9. 2003
    ..Catechol-O-methyltransferase (COMT) is an enzyme involved in catecholamine inactivation. In this study, we examined the influence of a functional COMT (V158M) polymorphism on suicidal behavior and anger-related traits...
  37. ncbi request reprint Auditory cortex and anterior cingulate cortex sources of the early evoked gamma-band response: relationship to task difficulty and mental effort
    Christoph Mulert
    Department of Psychiatry, LMU, Nussbaumstrasse 7, D 80336 Munich, Germany
    Neuropsychologia 45:2294-306. 2007
    ..These findings are in line with a top-down influence of dACC-activity to the auditory association area 22 during the early evoked GBR...
  38. ncbi request reprint Kinematical analysis of motor function in schizophrenic patients: a possibility to separate negative symptoms from extrapyramidal dysfunction induced by neuroleptics?
    Verena Henkel
    Department of Psychiatry, Ludwig Maximilians University Munich, Munich, Germany
    Pharmacopsychiatry 37:110-8. 2004
    ..In this prospective matched case-control study, hand movement analysis was conducted using a digitizing tablet (kinematical analysis)...
  39. doi request reprint Influence of ANKK1 and DRD2 polymorphisms in response to haloperidol
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 263:65-74. 2013
    ..Our findings support a possible role of ANKK1 and DRD2 variability on haloperidol efficacy. However, due to the discrepancies between the results in the two samples, our results need further validation...
  40. doi request reprint Evaluating depressive symptoms in schizophrenia: a psychometric comparison of the Calgary Depression Scale for Schizophrenia and the Hamilton Depression Rating Scale
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Psychopathology 45:276-85. 2012
    ....
  41. ncbi request reprint Akathisia and suicidal ideation in first-episode schizophrenia
    Florian Seemüller
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    J Clin Psychopharmacol 32:694-8. 2012
    ..The allocated treatment, anxiety, and nervousness had no influence. The present findings suggest a promoting effect of akathisia on suicidal ideation can not be ruled out in patients with FES...
  42. doi request reprint Influencing factors and predictors of early improvement in the acute treatment of schizophrenia and schizophrenia spectrum disorder
    Rebecca Schennach-Wolff
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    J Psychiatr Res 45:1639-47. 2011
    ..To examine the influencing factors and predictors of early improvement in schizophrenia patients...
  43. doi request reprint The Munich 15-year follow-up study (MUFUSSAD) on first-hospitalized patients with schizophrenic or affective disorders: comparison of psychopathological and psychosocial course and outcome and prediction of chronicity
    Hans Jurgen Moller
    Department of Psychiatry, University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 260:367-84. 2010
    ..The Strauss-Carpenter Scale, male gender as well as several psychopathological syndromes are the most relevant predictors for chronicity...
  44. doi request reprint Inefficient neural activity in patients with schizophrenia and nonpsychotic relatives of schizophrenic patients: evidence from a working memory task
    Susanne Karch
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstrasse 7, D 80336 Munich, Germany
    J Psychiatr Res 43:1185-94. 2009
    ..In addition, compensatory strategies were demonstrated. These findings suggest that the genetic risk for schizophrenia is accompanied by neural inefficiency which is associated with cognitive deficits, especially in difficult tasks...
  45. ncbi request reprint Differentiation of geriatric major depression from Alzheimer's disease with CSF tau protein phosphorylated at threonine 231
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Am J Psychiatry 160:376-9. 2003
    ..The authors asked whether p-tau(231) levels improve the differential diagnosis between geriatric major depression and Alzheimer's disease...
  46. ncbi request reprint Association analysis of a polymorphism in the G-protein stimulatory alpha subunit in patients with major depression
    Peter Zill
    Psychiatric Hospital of the Ludwig Maximilians University, Munich, Germany
    Am J Med Genet 114:530-2. 2002
    ....
  47. ncbi request reprint Beta-1-adrenergic receptor gene in major depression: influence on antidepressant treatment response
    Peter Zill
    Psychiatric Hospital of the Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 120:85-9. 2003
    ..05). However, after correction for multiple testing (Bonferroni) these results did not remain significant. Nevertheless, these findings suggest that the presence of the C allele might be an indicator for antidepressant treatment response...
  48. ncbi request reprint A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: molecular, cellular, functional and behavioral abnormalities
    Dan Rujescu
    Division of Molecular and Clinical Neurobiology, Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 59:721-9. 2006
    ....
  49. ncbi request reprint P300 subcomponents in obsessive-compulsive disorder
    Paraskevi Mavrogiorgou
    Department of Psychiatry, Section of Clinical Neurophysiology and Outpatient Clinic for Obsessive Compulsive Disorder, Ludwig Maximilians University Munich, Germany
    J Psychiatr Res 36:399-406. 2002
    ....
  50. pmc Glutamatergic dysbalance and oxidative stress in in vivo and in vitro models of psychosis based on chronic NMDA receptor antagonism
    Just Genius
    Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
    PLoS ONE 8:e59395. 2013
    ....
  51. ncbi request reprint Prefrontal cortex stimulation as antidepressant treatment: mode of action and clinical effectiveness of rTMS
    Frank Padberg
    Department of Psychiatry, Ludwig Maximilian University, Nussbaumstr 7, D 80336 Munich, Germany
    Suppl Clin Neurophysiol 56:406-32. 2003
  52. ncbi request reprint Negative symptoms in depressed and schizophrenic patients: how do they differ?
    Ronald Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    J Clin Psychiatry 64:954-8. 2003
    ..nonenduring) can help to improve their specificity for schizophrenia...
  53. ncbi request reprint NOS-I and -III gene variants are differentially associated with facets of suicidal behavior and aggression-related traits
    Dan Rujescu
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 147:42-8. 2008
    ..0002; sliding haplotype T-G, P = 0.002). In conclusion, our study suggests a possible involvement of NOS-I and NOS-III gene variants in suicidal behavior and related intermediate phenotypes...
  54. ncbi request reprint World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of bipolar disorders. Part I: Treatment of bipolar depression
    Heinz Grunze
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    World J Biol Psychiatry 3:115-24. 2002
    ..As these guidelines are intended for clinical use, the scientific evidence was not only graded, but also commented on by the experts of the task force to ensure practicability...
  55. ncbi request reprint Use of brief depression screening tools in primary care: consideration of heterogeneity in performance in different patient groups
    Verena Henkel
    Department of Psychiatry, Ludwig Maximilians University Munich, Nussbaumstr 7, D 80336 Munich, Germany
    Gen Hosp Psychiatry 26:190-8. 2004
    ..This should be considered if routine depression screening should be widely introduced. Of course, the benefit of routine screening also depends on efforts made for treatment and monitoring of patients in whom depression was diagnosed...
  56. ncbi request reprint Sound level dependence of the primary auditory cortex: Simultaneous measurement with 61-channel EEG and fMRI
    Christoph Mulert
    Department of Psychiatry, LMU, Munich, Germany
    Neuroimage 28:49-58. 2005
    ..In addition, the correspondence of the ERP-based data and the fMRI results further supports the validity of the ERP localization approach...
  57. doi request reprint Influence of neuronal cell adhesion molecule (NCAM1) variants on suicidal behaviour and correlated traits
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 179:222-5. 2010
    ..However, independent studies are needed to validate these results...
  58. ncbi request reprint On the descriptive validity of ICD-10 schizophrenia: empirical analyses in the spectrum of non-affective functional psychoses
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychopathology 36:152-9. 2003
    ..The results are in line with a high descriptive validity of ICD-10 schizophrenia and highlight the importance of negative symptoms for this diagnosis...
  59. ncbi request reprint Does clinical judgment of baseline severity and changes in psychopathology depend on the patient population? Results of a CGI and PANSS linking analysis in a naturalistic study
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Munich, Germany
    J Clin Psychopharmacol 30:726-31. 2010
    ..Furthermore, these linking results were compared with those derived from randomized controlled trials to examine if the baseline severity might influence the linking results...
  60. doi request reprint Predictors of response and remission in the acute treatment of first-episode schizophrenia patients--is it all about early response?
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Eur Neuropsychopharmacol 21:370-8. 2011
    ..To evaluate the predictive validity of early response compared to other well-known predictor variables in acutely ill first-episode patients...
  61. doi request reprint NCAM1, TACR1 and NOS genes and temperament: a study on suicide attempters and controls
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Neuropsychobiology 64:32-7. 2011
    ....
  62. ncbi request reprint Prediction of treatment response in major depression: integration of concepts
    Christoph Mulert
    Department of Psychiatry, LMU, Munich, Germany
    J Affect Disord 98:215-25. 2007
    ..Here, a high LDAEP is supposed to reflect low central serotonergic activity. We present the first study comparing both approaches in the same group of patients...
  63. pmc Psychopathological characteristics and treatment response of first episode compared with multiple episode schizophrenic disorders
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 257:47-53. 2007
    ..The aim was to investigate the hypothesis that patients with first episode schizophrenic disorders have a more favorable treatment response than those with multiple episodes...
  64. ncbi request reprint ABCG1 gene variants in suicidal behavior and aggression-related traits
    Anton Gietl
    Molecular and Clinical Neurobiology, Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    Eur Neuropsychopharmacol 17:410-6. 2007
    ..Given that these represent intermediate phenotypes of suicidal behavior, ABCG1 might also act on suicidal behavior through these traits. The observed associations warrant further replications...
  65. ncbi request reprint Effects of risperidone and quetiapine on cognition in patients with schizophrenia and predominantly negative symptoms
    Michael Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 257:360-70. 2007
    ..Also, the improvements in cognition following treatment with quetiapine and risperidone may enhance long-term outcomes for these patients...
  66. ncbi request reprint Serotonergic dysfunction in schizophrenia assessed by the loudness dependence measure of primary auditory cortex evoked activity
    Georg Juckel
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 64:115-24. 2003
    ..These results suggest that the loudness dependence of primary auditory cortex evoked activity is well suitable to assess serotonergic dysfunction in schizophrenia...
  67. ncbi request reprint The gamma amino butyric acid (GABA) receptor alpha-3 subunit gene polymorphism in unipolar depressive disorder: a genetic association study
    Verena Henkel
    Department of Psychiatry, Ludwig Maximilians University Munich, Nussbaumstrasse 7, D 80336 Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 126:82-7. 2004
    ....
  68. pmc Orbitofrontal volume reductions during emotion recognition in patients with major depression
    Johanna Scheuerecker
    Department of Psychiatry, Ludwig Maximilians University Munich, Germany
    J Psychiatry Neurosci 35:311-20. 2010
    ..The relation between structural and functional changes is largely unknown. Therefore, we sought to determine the relation between structural differences and functional alterations during the recognition of emotional facial expressions...
  69. ncbi request reprint The dysbindin gene in major depression: an association study
    Peter Zill
    Psychiatric Hospital of the Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 129:55-8. 2004
    ..Further analysis are needed to confirm these results...
  70. ncbi request reprint Age transformation of combined hippocampus and amygdala volume improves diagnostic accuracy in Alzheimer's disease
    Harald Hampel
    Dementia Research and Neuroimaging Section, Memory Clinic, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstr 7, 80336, Munich, Germany
    J Neurol Sci 194:15-9. 2002
    ..We propose an adjustment for this age effect to increase the diagnostic accuracy of hippocampal volumes in AD...
  71. doi request reprint Personality and attempted suicide. Analysis of anger, aggression and impulsivity
    Ina Giegling
    Molecular and Clinical Neurobiology, Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    J Psychiatr Res 43:1262-71. 2009
    ..Such interactions could explain the correlation between temperament and suicidality but further research is needed. Anger and self-directedness appear to have some effects on suicide attempt...
  72. ncbi request reprint Effects of antidepressant pharmacotherapy after repetitive transcranial magnetic stimulation in major depression: an open follow-up study
    Cornelius Schule
    Department of Psychiatry, Ludwig Maximilian University, Nussbaumstr 7, 80336, Munich, Germany
    J Psychiatr Res 37:145-53. 2003
    ....
  73. ncbi request reprint Value of event-related P300 subcomponents in the clinical diagnosis of mild cognitive impairment and Alzheimer's Disease
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University Munich, Germany
    Psychophysiology 39:175-81. 2002
    ..Similar results were found using Pz amplitudes as well as Fz latencies. Our data suggest that TB-P300 amplitudes and TS-P300 latencies may be an accurate clinically available, nonexpensive, noninvasive, and reliable marker for AD...
  74. ncbi request reprint Relation between responses to repetitive transcranial magnetic stimulation and partial sleep deprivation in major depression
    Frank Padberg
    Department of Psychiatry, Ludwig Maximilian University, Nussbaumstr 7, 80336 Munich, Germany
    J Psychiatr Res 36:131-5. 2002
    ..Apparently, different subgroups of depressed patients respond to both interventions. Further studies are needed to characterize the response to rTMS by means of clinical and biological parameters...
  75. ncbi request reprint Progression of corpus callosum atrophy in Alzheimer disease
    Stefan J Teipel
    and Harald Hampel, MD, Dementia and Neuroimaging Section, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstr 7, 80336 Munich, Germany
    Arch Neurol 59:243-8. 2002
    ..Atrophy of the corpus callosum in the absence of primary white matter degeneration reflects loss of intracortical projecting neocortical pyramidal neurons in Alzheimer disease (AD)...
  76. ncbi request reprint The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders, part III: maintenance treatment
    Heinz Grunze
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    World J Biol Psychiatry 5:120-35. 2004
    ..As these guidelines are intended for clinical use, the scientific evidence was not only graded, but also reviewed by the experts of the task force to ensure practicality...
  77. ncbi request reprint Integration of fMRI and simultaneous EEG: towards a comprehensive understanding of localization and time-course of brain activity in target detection
    Christoph Mulert
    Department of Psychiatry, LMU, Nussbaumstrasse 7, 80336 Munich, Germany
    Neuroimage 22:83-94. 2004
    ..The results suggest that the combination of EEG and fMRI permits an improved understanding of the spatiotemporal dynamics of brain activity...
  78. ncbi request reprint Effects of tiagabine on cholecystokinin-tetrapeptide (CCK-4)-induced anxiety in healthy volunteers
    Peter Zwanzger
    Department of Psychiatry, University of Munich, Munich, Germany
    Depress Anxiety 18:140-3. 2003
    ..Our results suggest anxiolytic properties of tiagabine in humans, which provide sufficient rationale to assess its putative anxiolytic effects in patients with panic disorder under controlled conditions...
  79. doi request reprint Anterior cingulate cortex does not differ between patients with major depression and healthy controls, but relatively large anterior cingulate cortex predicts a good clinical course
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 163:76-83. 2008
    ..These findings suggest that ACC volumes are not altered in patients with major depression, but that patients with larger ACC have a better clinical outcome than patients with smaller ACC...
  80. ncbi request reprint Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study
    Harald Hampel
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Arch Gen Psychiatry 61:95-102. 2004
    ..Different tau phosphoepitopes can be sensitively detected in cerebrospinal fluid (CSF)...
  81. doi request reprint Is evaluation of humorous stimuli associated with frontal cortex morphology? A pilot study using facial micro-movement analysis and MRI
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, Germany
    Cortex 47:569-74. 2011
    ....
  82. ncbi request reprint Occurrence and treatment of depressive comorbidity/cosyndromality in schizophrenic psychoses: conceptual and treatment issues
    Hans Jurgen Moller
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 6:247-63. 2005
    ..Besides treatment with antidepressants, modern neuroleptics are of great importance in this context as they are more efficacious than classical neuroleptics in treating depressive symptoms...
  83. doi request reprint Attitude towards adherence in patients with schizophrenia at discharge
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    J Psychiatr Res 43:1294-301. 2009
    ....