Frauke Melchior

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. pmc Importin α/β mediates nuclear import of individual SUMO E1 subunits and of the holo-enzyme
    Marie Christine Moutty
    Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ ZMBH Alliance, Heidelberg, Germany
    Mol Biol Cell 22:652-60. 2011
  2. pmc Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex
    Volkan Sakin
    From the Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ, ZMBH Alliance, Heidelberg, Germany
    J Biol Chem 290:23589-602. 2015
  3. doi request reprint Reconstitution of the Recombinant RanBP2 SUMO E3 Ligase Complex
    Tobias Ritterhoff
    Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ ZMBH Alliance, Im Neuenheimer Feld 282, 69120, Heidelberg, Germany
    Methods Mol Biol 1475:41-54. 2016
  4. pmc SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression
    Achim Werner
    Zentrum fur Molekulare Biologie der Universitat Heidelberg, DKFZ ZMBH Alliance, Germany
    Nat Cell Biol 15:179-88. 2013
  5. doi request reprint Detecting endogenous SUMO targets in mammalian cells and tissues
    Janina Becker
    Zentrum für Molekulare Biologie Heidelberg, DKFZ ZMBH Alliance, Heidelberg, Germany
    Nat Struct Mol Biol 20:525-31. 2013

Collaborators

Detail Information

Publications5

  1. pmc Importin α/β mediates nuclear import of individual SUMO E1 subunits and of the holo-enzyme
    Marie Christine Moutty
    Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ ZMBH Alliance, Heidelberg, Germany
    Mol Biol Cell 22:652-60. 2011
    ..These pathways may serve distinct purposes: import of nascent subunits prior to assembly and reimport of stable E1 enzyme complex after mitosis...
  2. pmc Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex
    Volkan Sakin
    From the Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ, ZMBH Alliance, Heidelberg, Germany
    J Biol Chem 290:23589-602. 2015
    ..Recognition requires interaction of Ran with RanBP2's RBDs, which is prevented by the transport factor NTF2. ..
  3. doi request reprint Reconstitution of the Recombinant RanBP2 SUMO E3 Ligase Complex
    Tobias Ritterhoff
    Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ ZMBH Alliance, Im Neuenheimer Feld 282, 69120, Heidelberg, Germany
    Methods Mol Biol 1475:41-54. 2016
    ..Finally, we present details for the assembly and final purification of the catalytically active RanBP2/RanGAP1*SUMO1/Ubc9 complex. ..
  4. pmc SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression
    Achim Werner
    Zentrum fur Molekulare Biologie der Universitat Heidelberg, DKFZ ZMBH Alliance, Germany
    Nat Cell Biol 15:179-88. 2013
    ..Our findings identify SCF(Fbxw5)-driven fluctuation of Eps8 levels as an important mechanism that contributes to cell-shape changes during entry into-and exit from-mitosis...
  5. doi request reprint Detecting endogenous SUMO targets in mammalian cells and tissues
    Janina Becker
    Zentrum für Molekulare Biologie Heidelberg, DKFZ ZMBH Alliance, Heidelberg, Germany
    Nat Struct Mol Biol 20:525-31. 2013
    ..This protocol provides an affordable and feasible tool to investigate endogenous SUMOylation in primary cells, tissues and organs, and it will facilitate understanding of SUMO's role in physiology and disease...