K Mann

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. ncbi request reprint [Diagnosis and therapy of differentiated thyroid gland carcinomas]
    K Mann
    Abteilung für Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen
    Internist (Berl) 43:174-85. 2002
  2. ncbi request reprint [Subclinical hypothyroidism--what level of TSH is an indication for substitution?]
    K Mann
    European Endocrinologist U E M S, Klinik fur Endokrinologie, Universitatsklinikum Essen, Hufelandstrasse 55, D 45122 Essen
    MMW Fortschr Med 148:26-9. 2006
  3. ncbi request reprint [Etiology and pathophysiology of Graves' disease]
    K Mann
    Abteilung für Endokrinologie, Universitäts klinikums, Universität GHS Essen
    Z Arztl Fortbild Qualitatssich 93:29-34. 1999
  4. ncbi request reprint Glucose and lipid metabolism in young lean normotensive males with the G protein beta3 825T-allele
    B Saller
    Abteilung für Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen, Germany
    Eur J Med Res 8:91-7. 2003
  5. ncbi request reprint [Diagnosis and treatment of autoimmune thyroiditis]
    H Lahner
    Klinik fur Endokrinologie, Zentrum Innere Medizin, Universitatsklinikum Essen
    MMW Fortschr Med 146:28-30. 2004
  6. ncbi request reprint [Drug treatment of immune hyperthyroidism (Basedow disease). Patient selection, long-term follow-up and prevention of recurrence]
    B Quadbeck
    Klinik fur Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen
    Internist (Berl) 44:440-8. 2003
  7. ncbi request reprint [Hypophyseal coma]
    B L Herrmann
    Klinik fur Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen
    Internist (Berl) 44:1253-9. 2003
  8. ncbi request reprint [Problems and new developments in the management of Graves' disease: medical therapy]
    B Quadbeck
    Klinik fur Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen
    Z Arztl Fortbild Qualitatssich 98:37-44. 2004
  9. pmc Impact of smoking on the response to treatment of thyroid associated ophthalmopathy
    A Eckstein
    Department of Ophthalmology, University of Essen, Germany
    Br J Ophthalmol 87:773-6. 2003
  10. ncbi request reprint Myocardial perfusion abnormalities in patients with active acromegaly
    B L Herrmann
    Division of Endocrinology, University of Essen, Germany
    Horm Metab Res 35:183-8. 2003

Collaborators

Detail Information

Publications84

  1. ncbi request reprint [Diagnosis and therapy of differentiated thyroid gland carcinomas]
    K Mann
    Abteilung für Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen
    Internist (Berl) 43:174-85. 2002
  2. ncbi request reprint [Subclinical hypothyroidism--what level of TSH is an indication for substitution?]
    K Mann
    European Endocrinologist U E M S, Klinik fur Endokrinologie, Universitatsklinikum Essen, Hufelandstrasse 55, D 45122 Essen
    MMW Fortschr Med 148:26-9. 2006
    ..These questions should be investigated in prospective clinical studies...
  3. ncbi request reprint [Etiology and pathophysiology of Graves' disease]
    K Mann
    Abteilung für Endokrinologie, Universitäts klinikums, Universität GHS Essen
    Z Arztl Fortbild Qualitatssich 93:29-34. 1999
    ..Proof for this hypothetical scenario may allow for novel immunotherapeutic onsets in the near future...
  4. ncbi request reprint Glucose and lipid metabolism in young lean normotensive males with the G protein beta3 825T-allele
    B Saller
    Abteilung für Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen, Germany
    Eur J Med Res 8:91-7. 2003
    ..Furthermore, fasting cholesterol was significantly higher in TC compared to CC genotype (4.71 versus 3.96 mmol/l; p = 0.007) suggesting that enhanced G protein signalling might be associated with alterations of cholesterol metabolism...
  5. ncbi request reprint [Diagnosis and treatment of autoimmune thyroiditis]
    H Lahner
    Klinik fur Endokrinologie, Zentrum Innere Medizin, Universitatsklinikum Essen
    MMW Fortschr Med 146:28-30. 2004
    ..Early treatment not only alleviates the clinical symptoms, but may possibly also diminish the associated cardiovascular risk. In pregnant and sterile women subclinical hypothyroidism should always be treated...
  6. ncbi request reprint [Drug treatment of immune hyperthyroidism (Basedow disease). Patient selection, long-term follow-up and prevention of recurrence]
    B Quadbeck
    Klinik fur Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen
    Internist (Berl) 44:440-8. 2003
    ..Basal TSH (4 weeks after withdrawal of antithyroid drugs) is the best prognostic marker. Smoking and positive TSH-receptor-antibodies at the end of antithyroid theraphy are other risk factors...
  7. ncbi request reprint [Hypophyseal coma]
    B L Herrmann
    Klinik fur Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen
    Internist (Berl) 44:1253-9. 2003
    ..ACTH stimulation test, CRH stimulation test and insulin tolerance test (optional) should be performed after therapeutic compensation to determine pituitary function...
  8. ncbi request reprint [Problems and new developments in the management of Graves' disease: medical therapy]
    B Quadbeck
    Klinik fur Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen
    Z Arztl Fortbild Qualitatssich 98:37-44. 2004
    ..Future therapeutic recommendations will be based on selection criteria such as iodine supplementation, volume of goitre, smoking habits and basal TSH...
  9. pmc Impact of smoking on the response to treatment of thyroid associated ophthalmopathy
    A Eckstein
    Department of Ophthalmology, University of Essen, Germany
    Br J Ophthalmol 87:773-6. 2003
    ..The authors sought to determine if smoking also influences the course of TAO during treatment, and the efficacy of therapy...
  10. ncbi request reprint Myocardial perfusion abnormalities in patients with active acromegaly
    B L Herrmann
    Division of Endocrinology, University of Essen, Germany
    Horm Metab Res 35:183-8. 2003
    ..01). In conclusion, myocardial perfusion is impaired in patients with active acromegaly, thus representing an early stage of cardiac involvement in acromegaly that may be directly mediated by growth hormone excess...
  11. ncbi request reprint Maturation of thyroidal dendritic cells in Graves' disease
    B Quadbeck
    Division of Endocrinology, Department of Medicine, Uniiversity Clinic, Essen, Germany
    Scand J Immunol 55:612-20. 2002
    ..Expression of CD54 and CD83 did not significantly differ among the groups. The phenotype of intrathyroidal DC in GD thus supports their role as potential (co)stimulators of thyroid autoimmunity...
  12. ncbi request reprint Acromegaly: evidence for a direct relation between disease activity and cardiac dysfunction in patients without ventricular hypertrophy
    Burkhard L Herrmann
    Department of Internal Medicine, Division of Endocrinology, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Clin Endocrinol (Oxf) 56:595-602. 2002
    ..The impact of disease activity on LV performance in patients with normal or slightly elevated LV muscle mass has not been demonstrated...
  13. ncbi request reprint Effects of a combination of rhGH and metformin on adiponectin levels in patients with metabolic syndrome
    B L Herrmann
    Division of Endocrinology, Dept of Internal Medicine, University of Essen, Hufelandstrasse 55, 45147 Essen, Germany
    Horm Metab Res 37:49-52. 2005
    ..73; p = 0.004). In conclusion, the additional administration of rhGH increased adiponectin levels in patients with metabolic syndrome, indicating its potential role in adiponectin-associated insulin sensitivity alterations...
  14. ncbi request reprint Surveillance of TSH-suppressive levothyroxine treatment in thyroid cancer patients: TRH testing versus basal TSH determination by a third generation assay
    R Gorges
    Department of Nuclear Medicine, University Hospital Essen, Germany
    Exp Clin Endocrinol Diabetes 110:355-60. 2002
    ..1 mU/l) and by a 3 rd generation assay (lower detection limit 0.005 mU/l) in 209 thyroidectomized thyroid cancer patients under suppressive levothyroxine treatment...
  15. ncbi request reprint Long-term follow-up of thyroid nodule growth
    B Quadbeck
    Department of Medicine, University of Essen, Essen, Germany
    Exp Clin Endocrinol Diabetes 110:348-54. 2002
    ..In this study, not only nodular but even non-nodular goiter growth continues in the majority of patients. Exogeneous factors, including therapy with levothyroxine and/or iodide, appear to have little effect on the growth behaviour...
  16. ncbi request reprint Comorbidity of diabetes mellitus and eating disorders: a follow-up study
    S Herpertz
    Clinic of Psychotherapy and Psychosomatics, University of Essen, Postfach 103043, 45030 Essen, Germany
    J Psychosom Res 51:673-8. 2001
    ..There is increasing evidence that the coexistence of diabetes and eating disorders (ED) leads to poor glycemic control and an increased risk of long-term complications...
  17. ncbi request reprint Prevalence of the metabolic syndrome in German women with polycystic ovary syndrome
    S Hahn
    Division of Endocrinology, Department of Medicine, University Hospital of Essen Medical School, Essen, Germany
    Exp Clin Endocrinol Diabetes 115:130-5. 2007
    ..In PCOS women, while one out of three PCOS women had the MBS, the presence of metabolic abnormalities did not appear to be associated with PCOS per se, but rather correlated with age and the degree of obesity...
  18. ncbi request reprint The combination of increased ovarian volume and follicle number is associated with more severe hyperandrogenism in German women with polycystic ovary syndrome
    S Hahn
    Division of Endocrinology, Department of Medicine, University of Duisburg Essen, Essen, Germany
    Exp Clin Endocrinol Diabetes 114:175-81. 2006
    ..PCO are common finding in German PCOS women. PCO appear to be associated with a more pronounced hyperandrogenemia, especially when both ovarian volume and follicle number are increased...
  19. ncbi request reprint Prognostic value of c-erbB-2 expression in papillary thyroid carcinoma
    L S Freudenberg
    Department of Nuclear Medicine, University of Essen, Germany
    Nuklearmedizin 44:179-82, 184. 2005
    ..Objective of the study is to determine whether c-erbB-2 overexpression correlates with the clinical course...
  20. ncbi request reprint Hypopituitarism following severe traumatic brain injury
    B L Herrmann
    Institute of Cardio Diabetes, Technology Center Bochum, Bochum, Germany
    Exp Clin Endocrinol Diabetes 114:316-21. 2006
    ..These findings strongly suggest that patients who suffer head trauma must routinely include neuroendocrine evaluations...
  21. ncbi request reprint Development and clinical impact of thyroglobulin antibodies in patients with differentiated thyroid carcinoma during the first 3 years after thyroidectomy
    R Gorges
    Department of Nuclear Medicine, University of Duisburg Essen, Hufelandstrasse 55, 45 122 Essen, Germany
    Eur J Endocrinol 153:49-55. 2005
    ..With the advent of more sensitive assays, a longitudinal study monitoring the development of TgAb levels after ablative therapy was warranted...
  22. ncbi request reprint Effects of estrogen replacement therapy on bone and glucose metabolism in a male with congenital aromatase deficiency
    B L Herrmann
    Department of Endocrinology, University Hospital of Essen, Germany
    Horm Metab Res 37:178-83. 2005
    ..The optimal weekly dose of transdermal estrogen replacement for normalizing estrogen levels and maintain bone mass in adult males with aromatase deficiency may be 50-75 microg spread over two doses...
  23. ncbi request reprint Impact of smoking on the course of Graves' disease after withdrawal of antithyroid drugs
    B Quadbeck
    Division of Endocrinology, Department of Medicine, University of Duisburg Essen, Germany
    Exp Clin Endocrinol Diabetes 114:406-11. 2006
    ..Thus, our data suggest that smoking has modifying immunological consequences and an adverse impact on the course of GD after withdrawal of ATDT. Therefore, patients should be encouraged to stop smoking...
  24. ncbi request reprint Effects of octreotide on sleep apnoea and tongue volume (magnetic resonance imaging) in patients with acromegaly
    B L Herrmann
    Division of Endocrinology, Department of Internal Medicine, University of Essen, Hufelandstrasse 55, D 45 122 Essen, Germany
    Eur J Endocrinol 151:309-15. 2004
    ..Because the relationship between disease activity and severity of sleep apnoea is currently unclear, we have performed a prospective study to address this issue...
  25. ncbi request reprint Effects of a combination of recombinant human growth hormone with metformin on glucose metabolism and body composition in patients with metabolic syndrome
    B L Herrmann
    Division of Endocrinology, University of Essen, Germany
    Horm Metab Res 36:54-61. 2004
    ....
  26. ncbi request reprint Impact of disease activity on thyroid diseases in patients with acromegaly: basal evaluation and follow-up
    B L Herrmann
    Clinic of Endocrinology, Center of Internal Medicine, University of Essen, Germany
    Exp Clin Endocrinol Diabetes 112:225-30. 2004
    ..In conclusion, successful treatment of patients with active acromegaly decreases thyroid volume. Cold nodules and thyroid cancer frequently occur in acromegalic patients...
  27. ncbi request reprint RT-PCR-based detection of circulating calcitonin-producing cells in patients with advanced medullary thyroid cancer
    B Saller
    Division of Endocrinology, Department of Internal Medicine, University of Essen, 45122 Essen, Germany
    J Clin Endocrinol Metab 87:292-6. 2002
    ..RT-PCR results seem to reflect tumor spread and aggressiveness and thus may help with early identification of patients with disseminated and rapidly progressive disease...
  28. ncbi request reprint Bone loss in long-term survivors after transplantation of hematopoietic stem cells: a prospective study
    C Schulte
    Department of Medicine, University of Essen, Germany
    Osteoporos Int 11:344-53. 2000
    ..The observed alterations in bone mass and metabolism emphasize the importance of clinical trials with antiresorptive agents to prevent and treat post-transplantation osteoporosis in this group of patients...
  29. ncbi request reprint Relationship of weight and eating disorders in type 2 diabetic patients: a multicenter study
    S Herpertz
    Clinic of Psychotherapy and Psychosomatics, University of Essen, Essen, Germany
    Int J Eat Disord 28:68-77. 2000
    ..In a multicenter study, we investigated the relationship between weight and eating disorders (EDs) in a sample of type 2 diabetic patients...
  30. ncbi request reprint [Comorbidity of diabetes mellitus and eating disorders. A comparison of psychological features of eating disordered and non-eating disordered patients with diabetes mellitus]
    S Herpertz
    Klinik für Psychotherapie und Psychosomatik, Universtätsklinik Essen
    Psychother Psychosom Med Psychol 50:161-8. 2000
    ..With the exception of the variable body and figure satisfaction in the sample of type 1 diabetes and the variable self-acceptance in the sample of type 2 diabetes, no relationship to diabetic control could be found...
  31. ncbi request reprint T3-release from autonomously functioning thyroid nodules in vitro
    S Poertl
    Department of Medicine, University of Essen, Germany
    Exp Clin Endocrinol Diabetes 106:489-93. 1998
    ..The first stimulator may have clinical relevance in patients with toxic thyroid nodules and not yet suppressed TSH; the latter could play a role in the rare Marine Lenhart syndrome...
  32. ncbi request reprint Enhanced epinephrine-induced platelet aggregation in individuals carrying the G protein beta3 subunit 825T allele
    C Naber
    Abteilung fur Kardiologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen, Germany
    FEBS Lett 484:199-201. 2000
    ..This effect was more pronounced after inhibition of the cyclooxygenase-2 pathway by acetylsalicylic acid. This phenomenon appeared independent of platelet secretion, or inhibition of the adenylyl cyclase...
  33. ncbi request reprint Utility of third generation thyrotropin assays in thyroid function testing
    B Saller
    Department of Internal Medicine, University of Essen, Germany
    Exp Clin Endocrinol Diabetes 106:S29-33. 1998
    ..In conclusion, the use of third generation TSH assays is recommended in specialized clinical laboratories frequently analyzing samples taken in one of those clinical situations...
  34. ncbi request reprint Kinetics of acute and chronic iodine excess
    B Saller
    Department of Internal Medicine, University of Essen, Germany
    Exp Clin Endocrinol Diabetes 106:S34-8. 1998
    ..5-208.2 microg/dl, median 36.6 microg/dl). Serum concentrations of inorganic iodide were correlated neither to the daily amiodarone dose, nor to the serum levels of amiodarone...
  35. ncbi request reprint Circadian plasma leptin levels in patients with anorexia nervosa: relation to insulin and cortisol
    S Herpertz
    Clinic of Psychotherapy and Psychosomatics, University of Essen, Germany
    Horm Res 50:197-204. 1998
    ..Thus, anorexia nervosa leads to pronounced, albeit reversible changes in the secretion dynamics of leptin and cortisol...
  36. ncbi request reprint Comorbidity of diabetes and eating disorders. Does diabetes control reflect disturbed eating behavior?
    S Herpertz
    Clinic of Psychotherapy and Psychosomatics, University of Essen, Germany
    Diabetes Care 21:1110-6. 1998
    ....
  37. ncbi request reprint Diabetes mellitus and eating disorders: a multicenter study on the comorbidity of the two diseases
    S Herpertz
    Clinic of Psychotherapy and Psychosomatics, University of Essen, Germany Stephan
    J Psychosom Res 44:503-15. 1998
    ..8% vs. 3.7%, lifetime prevalence 2.6% vs. 5.9%). We conclude that eating disorders seem to be equally frequent in IDDM and NIDDM patients. However, there might be different features of eating disorders in both types of diabetes...
  38. ncbi request reprint Primary malignant fibrous histiocytoma of the lung: IGF-II producing tumor induces fasting hypoglycemia
    B L Herrmann
    Department of Medicine, University of Essen, Germany
    Exp Clin Endocrinol Diabetes 108:515-8. 2000
    ..In conclusion, malignant fibrous histiocytoma (MFH) is rarely described presenting as tumor-induced hypoglycemia. Doege-Potter Syndrome in MFH seems to be related to tumor-associated IGF-II production...
  39. ncbi request reprint Longitudinal changes of circadian leptin, insulin and cortisol plasma levels and their correlation during refeeding in patients with anorexia nervosa
    S Herpertz
    Clinic of Psychotherapy and Psychosomatics, University of Essen, Postfach 103043, D 45030 Essen, Germany
    Eur J Endocrinol 142:373-9. 2000
    ..To study the longitudinal changes in plasma levels of leptin, insulin and cortisol during the transition from the state of starvation to the state of refeeding focussing on diurnal secretion characteristics and their temporal relationships...
  40. doi request reprint Prevalence of anterior pituitary dysfunction in patients following traumatic brain injury in a German multi-centre screening program
    C Berg
    Clinic of Endocrinology, University Hospital of Essen, Germany
    Exp Clin Endocrinol Diabetes 118:139-44. 2010
    ..We determined the prevalence of anterior pituitary dysfunction in a multi-centre screening program across five German endocrine centres in patients rehabilitating from TBI (GCS<13)...
  41. ncbi request reprint Occurrence of ventricular late potentials in patients with active acromegaly
    B L Herrmann
    Division of Endocrinology, University of Essen, Germany
    Clin Endocrinol (Oxf) 55:201-7. 2001
    ..The aim of our study was to investigate the prevalence of late potentials in patients with acromegaly and their relation to the activity of the disease and to myocardial hypertrophy...
  42. ncbi request reprint [Video-assisted hemithyroidectomy: surgical technique and early results]
    M K Walz
    Klinik für Chirurgie und Zentrum für Minimal Invasive Chirurgie, Kliniken Essen Mitte
    Chirurg 72:1054-7. 2001
    ..No complications were observed. Videoscopically assisted hemithyroidectomy is feasible and can be considered in selected patients...
  43. ncbi request reprint [Transsphenoidal hypophysectomy of a patient with an ACTH-producing pituitary adenoma and an "empty sella" after pretreatment with etomidate]
    B L Herrmann
    Abt für Endokrinologie, Universitatsklinikum Essen
    Dtsch Med Wochenschr 126:232-4. 2001
    ..Computed tomography of the abdomen showed a 19 x 34 mm mass in the region of the left adrenal gland...
  44. ncbi request reprint [Thyroid carcinoma. Diagnosis--nonoperative therapy--after care]
    L Moller
    Zentrum fur Innere Medizin, Abteilung für Endokrinologie, Universitatsklinikum Essen
    MMW Fortschr Med 143:26-31. 2001
    ..In the event of a recurrence showing rapid progression, when surgical and nuclear medical treatment modalities have been exhausted, chemotherapy can be given...
  45. ncbi request reprint [Non-thyroid illness" or changed thyroid hormone parameter syndrome with non-thyroid illnesses]
    W Reinhardt
    Abteilung für Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen
    Med Klin (Munich) 93:662-8. 1998
    ..The multiple effects of systemic illness on thyroid economy are commonly referred to "non-thyroidal illness" (NTI) or "sick euthyroid syndrome". The various aspects of this common syndrome are summarized in this article...
  46. ncbi request reprint Residential exposure to traffic is associated with coronary atherosclerosis
    B Hoffmann
    Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Circulation 116:489-96. 2007
    ..5) air pollution may accelerate the development and progression of atherosclerosis. We investigated the associations of long-term residential exposure to traffic and fine particulate matter with the degree of coronary atherosclerosis...
  47. ncbi request reprint Repaglinide in the management of new-onset diabetes mellitus after renal transplantation
    T Turk
    Department of Nephrology and Hypertension, School of Medicine, University of Diusburg Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Am J Transplant 6:842-6. 2006
    ..The data from our observational study indicate that repaglinide can be an effective treatment option in Caucasian patients with NODM after renal transplantation...
  48. doi request reprint Influence of disease control with pegvisomant on sleep apnoea and tongue volume in patients with active acromegaly
    C Berg
    Division of Laboratory Research, Department of Endocrinology, Ruhrlandklinik, University of Duisburg Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Eur J Endocrinol 161:829-35. 2009
    ..We investigated the influence of disease activity on tongue volume and sleep apnoea treated with the GH receptor antagonist pegvisomant in poorly controlled patients with acromegaly under octreotide...
  49. ncbi request reprint [Rhabdomyolysis, hyponatremia and fever in a patient with Schmidt's syndrome]
    I Kordish
    Klinik fur Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen
    Dtsch Med Wochenschr 128:1649-52. 2003
    ..Two weeks before admission he had received non-steroid anti-inflammatory drugs (paracetamol and ibuprofen) after a tooth extraction. Some weeks before he had noticed a rough voice and a dry skin...
  50. ncbi request reprint [Metformin, an efficacious drug in the treatment of polycystic ovary syndrome]
    S Hahn
    Klinik fur Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen
    Dtsch Med Wochenschr 129:1059-64. 2004
    ..International studies showed a beneficial effect of metformin treatment on biochemical and reproductive parameters in PCOS. The aim of our study is the evaluation of metformin treatment in a German PCOS sample...
  51. ncbi request reprint [Biochemical markers of ischemic and non-ischemic myocardial damage]
    J Herrmann
    , ,
    Med Klin (Munich) 96:144-56. 2001
    ..CONCLUSION: Biochemical cardiac markers are a useful tool in the diagnosis of both ischemic and non-ischemic myocardial injury. Among these, cardiac troponins seem to become the gold markers for the new millennium...
  52. ncbi request reprint Differential expression of the human somatostatin receptor subtypes sst1 to sst5 in various adrenal tumors and normal adrenal gland
    B Ueberberg
    Division of Endocrinology, Medical Center, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Horm Metab Res 37:722-8. 2005
    ..New subtype specific analogues of SRIF may be used in the future depending on the type of adrenal tumor and receptor subtype expressed...
  53. ncbi request reprint Reduced availability of serotonin transporters in obsessive-compulsive disorder correlates with symptom severity - a [11C]DASB PET study
    M Reimold
    Department of Nuclear Medicine, University of Tubingen, Tubingen, Germany
    J Neural Transm 114:1603-9. 2007
    ..CONCLUSION. This PET study confirms a central role of the serotonergic system, particularly the thalamus in the pathogenesis of obsessive compulsive disorder...
  54. ncbi request reprint Evaluation of the ratio of T3 release stimulating antibodies to TSH-binding inhibiting antibodies during the course of Graves' disease
    R Hoermann
    Medizinische Klinik II, Klinikum Grosshadern, , Germany
    Horm Metab Res 22:183-7. 1990
    ..This phenomenon, however, is apparently not closely related to the course of disease...
  55. ncbi request reprint Differential T4 degradation pathways in young patients with preterminal and terminal renal failure
    O Witzke
    Department of Medicine, Division of Nephrology and Hypertension, University Hospital Essen, Hufelandstrasse 55, Essen, Germany
    Horm Metab Res 39:355-8. 2007
    ..The aim of this study is to analyze thyroid hormone parameters in large homogenous patient cohorts with preterminal (stage 4) and terminal (stage 5) renal failure in an area of low iodine intake...
  56. ncbi request reprint Treatment of acromegaly with the GH receptor antagonist pegvisomant in clinical practice: safety and efficacy evaluation from the German Pegvisomant Observational Study
    I Schreiber
    Pfizer Pharma GmbH, Karlsruhe, Germany
    Eur J Endocrinol 156:75-82. 2007
    ..The German Pegvisomant Observational Study (GPOS) was started to monitor long-term safety and efficacy of pegvisomant as prescribed in clinical practice...
  57. ncbi request reprint Dysregulation of TNF/TNFR superfamily members: a systemic link between intra- and extrathyroidal manifestations in Graves' disease
    B Quadbeck
    Division of Endocrinology, Department of Medicine, University of Duisburg Essen, Essen, Germany
    Scand J Immunol 64:523-30. 2006
    ..Monocytes, therefore, may serve as a suitable target to therapeutically address the common precursor of key promoters of GD...
  58. ncbi request reprint Obesity, depression, and chronic low-grade inflammation in women with polycystic ovary syndrome
    S Benson
    Department of Medical Psychology and Behavioral Immunobiology, University Hospital of Essen, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Brain Behav Immun 22:177-84. 2008
    ..Since depression is common in PCOS, this study aimed to address whether depression correlates with indices of chronic low-grade inflammation beyond the association with obesity...
  59. doi request reprint Chemotherapy with doxorubicin in progressive medullary and thyroid carcinoma of the follicular epithelium
    A Matuszczyk
    Division of Endocrinology, University of Duisburg Essen, Essen, Germany
    Horm Metab Res 40:210-3. 2008
    ..Doxorubicin can be a valid chemotherapy option, especially for advanced or metastatic thyroid carcinoma of the follicular epithelium...
  60. doi request reprint Expression and mutation analysis of the tyrosine kinase c-kit in poorly differentiated and anaplastic thyroid carcinoma
    M Broecker-Preuss
    Department of Endocrinology, Division of Clinical Chemistry and Laboratory Medicine, University Hospital Essen, Hufelandstrasse 55, Essen, Germany
    Horm Metab Res 40:685-91. 2008
    ..Further molecular targets of imatinib mesylate have to be analyzed to estimate a potential benefit of this drug for patients with dedifferentiated thyroid carcinoma...
  61. ncbi request reprint Galantamine reduces smoking in alcohol-dependent patients: a randomized, placebo-controlled trial
    A Diehl
    Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany
    Int J Clin Pharmacol Ther 44:614-22. 2006
    ..Galantamine is an acetylcholinesterase inhibitor that increases the effect of acetylcholine (ACh). The nicotinic ACh receptor is activated via positive allosteric modulation (APL)...
  62. ncbi request reprint Low serum 25-hydroxyvitamin D concentrations are associated with insulin resistance and obesity in women with polycystic ovary syndrome
    S Hahn
    Endokrinologikum Ruhr, Center for Metabolic and Endocrine Diseases, Bochum, Germany
    Exp Clin Endocrinol Diabetes 114:577-83. 2006
    ..In conclusion, in PCOS women, low 25-OH-VD levels are associated with obesity and insulin resistance but not with PCOS per se...
  63. ncbi request reprint Elevated transaminases during medical treatment of acromegaly: a review of the German pegvisomant surveillance experience and a report of a patient with histologically proven chronic mild active hepatitis
    H Biering
    Department of Gastroenterology, Hepatology and Endocrinology, Charite Universitatsmedizin Berlin, Germany
    Eur J Endocrinol 154:213-20. 2006
    ....
  64. ncbi request reprint Transient stimulatory effects on pituitary-thyroid axis in patients treated with interleukin-2
    O Witzke
    Department of Medicine, University Clinic Essen, Germany
    Thyroid 11:665-70. 2001
    ..Our data clearly demonstrate that the administration of interleukin-2 has a stimulatory effect on the pituitary-thyroid axis. The increase of TSH suggests a central stimulation directed by the action of IL-2 as the major mechanism...
  65. ncbi request reprint Human chorionic gonadotropin exhibits normal biological activity in patients with recurrent pregnancy loss
    K Kato
    Department of Obstetrics and Gynecology, University of Essen, Essen, Germany
    Gynecol Endocrinol 16:179-86. 2002
    ..Intrinsic gonadotropic and thyrotropic activities of the hCG molecule appear to play no major role in recurrent pregnancy loss...
  66. ncbi request reprint [Standardized documentation procedure as a basis for improvement of process quality of treatment in psychiatric hospitals]
    K Mann
    Psychiatrische Klinik der Universität Mainz
    Nervenarzt 74:235-44. 2003
    ..Moreover, in psychiatric care research, it is an adequate basis for evaluating the effectiveness and efficiency of treatment procedures...
  67. ncbi request reprint Mutations of the ret protooncogene in German multiple endocrine neoplasia families: relation between genotype and phenotype. German Medullary Thyroid Carcinoma Study Group
    K Frank-Raue
    Medizinische Universitatsklinik, Heidelberg, Germany
    J Clin Endocrinol Metab 81:1780-3. 1996
    ....
  68. ncbi request reprint Calcitonin measurement to detect medullary thyroid carcinoma in nodular goiter: German evidence-based consensus recommendation
    W Karges
    Department of Internal Medicine, University of Ulm, Ulm, Germany
    Exp Clin Endocrinol Diabetes 112:52-8. 2004
    ..Therefore, regular clinical and biochemical follow-up is the preferred treatment in such patients, unless thyroid malignancy is suspected otherwise...
  69. pmc Thyroid associated ophthalmopathy: evidence for CD4(+) gammadelta T cells; de novo differentiation of RFD7(+) macrophages, but not of RFD1(+) dendritic cells; and loss of gammadelta and alphabeta T cell receptor expression
    A K Eckstein
    Department of Ophthalmology, Essen University Hospital, Essen, Germany
    Br J Ophthalmol 88:803-8. 2004
    ..To characterise periorbital immune cells (stages, kinetics) in active and inactive thyroid associated ophthalmopathy (A-TAO; I-TAO)...
  70. ncbi request reprint Binding, stimulating and blocking TSH receptor antibodies to the thyrotropin receptor as predictors of relapse of Graves' disease after withdrawal of antithyroid treatment
    B Quadbeck
    Division of Endocrinology, Department of Medicine, University of Duisburg Essen, Germany
    Horm Metab Res 37:745-50. 2005
    ..In conclusion, differentiation of TRAb into TSAb and TBAb is of no help in the prediction of relapse of GD in euthyroid patients at the end of ATDT, and only high TRAb levels are associated with relapse...
  71. ncbi request reprint Role of conventional ultrasound and color Doppler sonography in the diagnosis of medullary thyroid carcinoma
    B Saller
    Department of Internal Medicine, University of Essen, Germany
    Exp Clin Endocrinol Diabetes 110:403-7. 2002
    ..In addition, the findings may have implications for calcitonin screening in nodular thyroid disease...
  72. ncbi request reprint Clinical and biochemical characterization of women with polycystic ovary syndrome in North Rhine-Westphalia
    S Hahn
    Div of Endocrinology, Dept of Medicine, University of Duisburg and Essen, 45122 Essen, Germany
    Horm Metab Res 37:438-44. 2005
    ..While the clinical characteristics and endocrine parameters of this German PCOS cohort were heterogeneous, they were comparable to those from other Caucasian populations...
  73. ncbi request reprint Gene-gene effects on central processing of aversive stimuli
    M N Smolka
    Department of Psychiatry, Technische Universitat Dresden, Dresden, Germany
    Mol Psychiatry 12:307-17. 2007
    ..Effects of 5-HTT and COMT genotypes did not affect brain processing of pleasant stimuli. These data indicate that functional brain imaging may be used to assess the interaction of multiple genes on the function of neuronal networks...
  74. ncbi request reprint Gliquidone therapy of new-onset diabetes mellitus after kidney transplantation
    T R Tuerk
    Department of Nephrology, University Hospital Essen, University of Duisburg Essen, Germany
    Clin Nephrol 70:26-32. 2008
    ..However, classic sulphonylureas have not been studied in transplanted patients to date. The purpose of this study was to investigate the use of gliquidone in NODM after renal transplantation...
  75. ncbi request reprint Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan
    M Hopf
    Max Planck Institut fur Biochemie, Martinsried, D 82152, Germany
    J Mol Biol 311:529-41. 2001
    ..This implicates a complex cluster of heterotypic interaction sites apparently important for the supramolecular organization of perlecan in tissues...
  76. doi request reprint Psychological implications of infertility in women with polycystic ovary syndrome
    S Tan
    Division of Endocrinology, Department of Medicine, University Hospital of Essen, University of Duisburg Essen, Essen, Germany
    Hum Reprod 23:2064-71. 2008
    ..Little is known regarding the psychological aspects associated with infertility in these patients. Therefore, we examined the influence of an unfulfilled wish to conceive on various aspects of psychological functioning in PCOS women...
  77. ncbi request reprint Ovocalyxin-32, a novel chicken eggshell matrix protein. isolation, amino acid sequencing, cloning, and immunocytochemical localization
    J Gautron
    Station de Recherches Avicoles, Institut National de la Recherche Agronomique, Nouzilly, 37380 France
    J Biol Chem 276:39243-52. 2001
    ..Ovocalyxin-32 is therefore identified as a novel protein synthesized in the distal oviduct where hen eggshell formation occurs...
  78. doi request reprint [Substance abuse prevention in the workplace: theoretical knowledge and expertise after interventions]
    S Loeber
    Lehrstuhl für Suchtforschung der Universität Heidelberg, Klinik für Abhängiges Verhalten und Suchtmedizin, Zentralinstitut fur Seelische Gesundheit, Mannheim
    Fortschr Neurol Psychiatr 76:92-6. 2008
    ..As an alternative, based on previous experiences we propose a series of workshops with role-plays and feedback to establish expertise in interviewing techniques with substance-related problems...
  79. ncbi request reprint [Evidence-based treatment of alcoholism]
    F Kiefer
    Klinik für Abhängiges Verhalten und Suchtmedizin, Zentralinstitut fur Seelische Gesundheit, Universitat Heidelberg, J5, 68159 Mannheim
    Nervenarzt 78:1321-9; quiz 1330-1. 2007
    ....
  80. ncbi request reprint [Pharmacological relapse prevention in alcohol and tobacco dependence]
    A Diehl
    Klinik für Abhängiges Verhalten und Suchtmedizin, Zentralinstitut fur Seelische Gesundheit, J5, 68159, Mannheim, Germany
    Internist (Berl) 48:79-84, 86-8. 2007
    ..A specific application of these substances will optimise the outcome for alcohol and tobacco dependent patients...
  81. ncbi request reprint [Psychosocial treatment plus drug prophylaxis. Fewer recurrences after alcohol withdrawal]
    M N Smolka
    Klinik für Abhängiges Verhalten und Suchtmedizin, Zentralinstitut fur Seelische Gesundheit, Universitat Heidelberg, J5, D 68159 Mannheim
    MMW Fortschr Med 145:45. 2003
  82. ncbi request reprint The human chorionic gonadotropin molecule from patients with trophoblastic diseases has a high thyrotropic activity but is less active in the ovary
    K Kato
    Department of Obstetrics and Gynecology, University of Essen, Essen, Germany
    Gynecol Endocrinol 18:269-77. 2004
    ..These results indicate that the hCG molecule from women with trophoblastic diseases displays enhanced thyrotropic activity...
  83. ncbi request reprint Serotonin reuptake inhibitor provoked recurrence of alcohol hallucinosis--remission with additive amisulpride medication. A case report
    D Hermann
    Pharmacopsychiatry 37:90-2. 2004
  84. ncbi request reprint Diagnosis of adrenal insufficiency: Evaluation of the corticotropin-releasing hormone test and Basal serum cortisol in comparison to the insulin tolerance test in patients with hypothalamic-pituitary-adrenal disease
    I Lopez Schmidt
    Division of Endocrinology, Medical Center, University of Essen, 45122 Essen, Germany
    J Clin Endocrinol Metab 88:4193-8. 2003
    ..Basal cortisol is less expensive, and we therefore suggest to use it as a first-line test of adrenal insufficiency. Because of the low sensitivity of the human CRH test, we do not recommend it as a second test...