Wolfgang Maier

Summary

Affiliation: University of Freiburg
Country: Germany

Publications

  1. ncbi request reprint Prognostic relevance of anamnestic and diagnostic parameters in low-frequency hearing impairment
    W Maier
    Department of Oto Rhino Laryngology, University of Freiburg Medical School, Freiburg, Germany
    J Laryngol Otol 120:613-8. 2006
  2. ncbi request reprint [Electrophysiologic examinations in low frequency hearing impairment: clinical and prognostic aspects]
    W Maier
    Universitäts HNO Klinik Freiburg
    Laryngorhinootologie 83:824-30. 2004
  3. ncbi request reprint Results of exploratory tympanotomy following sudden unilateral deafness and its effects on hearing restoration
    Wolfgang Maier
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Ludwigs University Medical School, Killianstr 5, D 79106 Freiburg, Germany
    Ear Nose Throat J 87:438-51. 2008
  4. ncbi request reprint [Multidisciplinary management of skull base and craniocervical chordoma]
    W Maier
    Klinik fur Hals, Nasen, und Ohren Heilkunde, Killianstrasse 5, 79106 Freiburg
    Laryngorhinootologie 85:272-8. 2006
  5. ncbi request reprint [Cochlear protection and surgical precision in stapedotomy with Er:YAG laser]
    W Maier
    Klinik fur Hals, Nasen und Ohren Heilkunde, Universitätsklinikum Freiburg i Br
    Laryngorhinootologie 85:333-7. 2006
  6. doi request reprint Clinical outcome after cochlear implantation in patients with unilateral hearing loss due to labyrinthitis ossificans
    Frederike Hassepass
    Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Freiburg, Freiburg, Germany
    Otol Neurotol 34:1278-83. 2013
  7. doi request reprint A novel dominant and a de novo mutation in the GJB2 gene (connexin-26) cause keratitis-ichthyosis-deafness syndrome: implication for cochlear implantation
    Susan Arndt
    Department of Otorhinolaryngology, Head and Neck Surgery University Medical Center Freiburg, Freiburg, Germany
    Otol Neurotol 31:210-5. 2010
  8. doi request reprint Revision surgery due to magnet dislocation in cochlear implant patients: an emerging complication
    Frederike Hassepass
    Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Freiburg, Freiburg, Germany
    Otol Neurotol 35:29-34. 2014
  9. ncbi request reprint Malignant head and neck paragangliomas in SDHB mutation carriers
    Carsten Christof Boedeker
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    Otolaryngol Head Neck Surg 137:126-9. 2007
  10. doi request reprint Giant cell reparative granuloma of the temporal bone
    Melanie Menge
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    Acta Neurochir (Wien) 151:397-9. 2009

Collaborators

Detail Information

Publications106 found, 100 shown here

  1. ncbi request reprint Prognostic relevance of anamnestic and diagnostic parameters in low-frequency hearing impairment
    W Maier
    Department of Oto Rhino Laryngology, University of Freiburg Medical School, Freiburg, Germany
    J Laryngol Otol 120:613-8. 2006
    ..Furthermore, these results help to distinguish valuable from irrelevant diagnostic procedures...
  2. ncbi request reprint [Electrophysiologic examinations in low frequency hearing impairment: clinical and prognostic aspects]
    W Maier
    Universitäts HNO Klinik Freiburg
    Laryngorhinootologie 83:824-30. 2004
    ..Electrophysiologic examinations are widely recommended in diagnostics of LFHI, wheras up to now no data exist about the prognostic value of these examinations in a conservative therapeutic regimen...
  3. ncbi request reprint Results of exploratory tympanotomy following sudden unilateral deafness and its effects on hearing restoration
    Wolfgang Maier
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Ludwigs University Medical School, Killianstr 5, D 79106 Freiburg, Germany
    Ear Nose Throat J 87:438-51. 2008
    ..We recommend that EXT be performed on all patients with new-onset acute unilateral deafness, barring any contraindications, of course. The absence of a typical history of PLF should not dissuade the surgeon from proceeding with EXT...
  4. ncbi request reprint [Multidisciplinary management of skull base and craniocervical chordoma]
    W Maier
    Klinik fur Hals, Nasen, und Ohren Heilkunde, Killianstrasse 5, 79106 Freiburg
    Laryngorhinootologie 85:272-8. 2006
    ..The localisation and locally-destructive growth require a multidisciplinary diagnostic and therapeutic concept early on. The goal of the present study was to present a reproducible strategy for quality assurance...
  5. ncbi request reprint [Cochlear protection and surgical precision in stapedotomy with Er:YAG laser]
    W Maier
    Klinik fur Hals, Nasen und Ohren Heilkunde, Universitätsklinikum Freiburg i Br
    Laryngorhinootologie 85:333-7. 2006
    ..We analyzed the clinical effect of Er:YAG laser with the question whether the postulated cochlea protection and foot plate perforation, optimized for better sound conduction, are achieved, compared to conventional stapedotomy...
  6. doi request reprint Clinical outcome after cochlear implantation in patients with unilateral hearing loss due to labyrinthitis ossificans
    Frederike Hassepass
    Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Freiburg, Freiburg, Germany
    Otol Neurotol 34:1278-83. 2013
    ..The aim of this clinical case study was to evaluate audiologic and subjective outcomes after CI treatment for unilateral hearing loss (UHL) because of LO and to identify optimal timing for treatment...
  7. doi request reprint A novel dominant and a de novo mutation in the GJB2 gene (connexin-26) cause keratitis-ichthyosis-deafness syndrome: implication for cochlear implantation
    Susan Arndt
    Department of Otorhinolaryngology, Head and Neck Surgery University Medical Center Freiburg, Freiburg, Germany
    Otol Neurotol 31:210-5. 2010
    ..The aim of this study was to explore the feasibility and procedure of cochlear implantation in patients with KID syndrome and to assess the genetic causes...
  8. doi request reprint Revision surgery due to magnet dislocation in cochlear implant patients: an emerging complication
    Frederike Hassepass
    Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Freiburg, Freiburg, Germany
    Otol Neurotol 35:29-34. 2014
    ..To analyze the cause and effect of magnet dislocation in cochlear implant (CI) recipients requiring magnet revision surgery for treatment...
  9. ncbi request reprint Malignant head and neck paragangliomas in SDHB mutation carriers
    Carsten Christof Boedeker
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    Otolaryngol Head Neck Surg 137:126-9. 2007
    ..The objective of this study was to investigate whether PGLs are associated with malignant head and neck paragangliomas (HNPs)...
  10. doi request reprint Giant cell reparative granuloma of the temporal bone
    Melanie Menge
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    Acta Neurochir (Wien) 151:397-9. 2009
    ..We present a case of GCRG of the left temporal bone that was treated surgically via a combined transtemporal-subtemporal approach. A short literature review about diagnosis, clinical behavior and treatment of this tumor entity is given...
  11. doi request reprint Radiologic Results and Hearing Preservation With a Straight Narrow Electrode via Round Window Versus Cochleostomy Approach at Initial Activation
    Frederike Hassepass
    Departments of Otorhinolaryngology Head and Neck Surgery, and Nuclear Medicine, University Medical Centre Freiburg, Freiburg, Germany
    Otol Neurotol 36:993-1000. 2015
    ..To evaluate the potential influence of two different cochlear implant (CI) electrode carrier approaches to the scala tympani in terms of insertion depth and angle as well as hearing preservation...
  12. doi request reprint The new mid-scala electrode array: a radiologic and histologic study in human temporal bones
    Frederike Hassepass
    Department of Otorhinolaryngology Head and Neck Surgery, Department of Radiology, and Institute of Musicians Medicine, Freiburg University Medical Center, Freiburg, Germany
    Otol Neurotol 35:1415-20. 2014
    ..To analyze the quality of insertion of the newly developed midscala (MS) electrode, which targets a midscalar electrode position to reduce the risk of trauma to the lateral wall and the modiolus...
  13. ncbi request reprint Laryngotracheal reconstruction using prefabricated and preconditioned composite radial forearm free flaps. A report of two cases
    Jörg Schipper
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Ludwigs University, Killianstrasse 5, 79106 Freiburg, Germany
    Auris Nasus Larynx 34:253-8. 2007
    ..The hitherto published reconstructive methods for the rehabilitation of patients after subtotal anterior laryngotracheal resection of extended laryngotracheal malignancies have not been thoroughly convincing...
  14. ncbi request reprint Imaging procedures after bone-anchored hearing aid implantation
    Susan Arndt
    Department of Oto Rhino Laryngology, Head and Neck Surgery, University Medical Center Freiburg, Freiburg, Germany
    Laryngoscope 117:1815-8. 2007
  15. ncbi request reprint Endolymphatic sac tumours: surgical management
    Jörg Schipper
    Department of Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    J Otolaryngol 35:387-94. 2006
    ..The latter association was first observed in 1992 and confirmed by molecular genetic analysis of the VHL gene. No consensual diagnostic and treatment strategy of ELST exists at present...
  16. ncbi request reprint Amputation neuroma of the middle ear mimicking glomus tympanicum tumor
    Meike Schikschneit
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    Otolaryngol Head Neck Surg 137:843-4. 2007
  17. doi request reprint Is there an equivalence of non-invasive to invasive referenciation in computer-aided surgery?
    Tanja D Grauvogel
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Ludwigs University Medical School, Killianstr 5, 79106 Freiburg, Germany
    Eur Arch Otorhinolaryngol 269:2285-90. 2012
    ..Therefore, invasive referenciation systems should be preferred in high precision surgery...
  18. doi request reprint Spectrum of hearing disorders and their management in children with CHARGE syndrome
    Susan Arndt
    Department of Oto Rhino Laryngology, Head and Neck Surgery, University Medical Center Freiburg, Freiburg, Germany
    Otol Neurotol 31:67-73. 2010
    ..The aim of this study is to explore the feasibility and procedure of cochlear implantation in patients with CHARGE syndrome and to assess the outcome...
  19. ncbi request reprint Entire infrasellar craniopharyngioma simulating clival chordoma
    Susan Arndt
    Department of Oto Rhino Laryngology, Head and Neck Surgery, University Medical Center Freiburg, Freiburg, Germany
    Otolaryngol Head Neck Surg 137:981-3. 2007
  20. ncbi request reprint Brainstem response in cerebellopontine angle tumors
    N Marangos
    Department of Otorhinolaryngology, Albert-Ludwigs-University, Freiburg, Germany
    Otol Neurotol 22:95-9. 2001
    ..ABR is not sufficient for early detection of small CPA tumors...
  21. doi request reprint The bonebridge as a transcutaneous bone conduction hearing system: preliminary surgical and audiological results in children and adolescents
    Frederike Hassepass
    Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Freiburg, Killianstr 5, 79106, Freiburg, Germany
    Eur Arch Otorhinolaryngol 272:2235-41. 2015
    ..BB implantation in patients ≤18 years is currently an "off-label use" so that detailed information about alternative treatment options, operation risks and the lack of approval for use in children is essential...
  22. doi request reprint Device setting modifications for 3D flatpanel imaging in skull base surgery
    Frederike Hassepass
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Freiburg, Killianstr 5, 79106 Freiburg, Germany
    Eur Arch Otorhinolaryngol 269:2145-51. 2012
    ..194 vs. 2.809, p < 0.0001). New C-arm systems with 3D-capabiltity offer a promising tool for intraoperative near real-time image guidance. Image quality of the skull base can be improved significantly with optimized system settings...
  23. pmc Rare extracranial localization of primary intracranial neoplasm
    Susan Arndt
    Department of Oto Rhino Laryngology, Head and Neck Surgery University Medical Center Freiburg, Germany
    Diagn Pathol 3:14. 2008
    ..In all cases of intranasal or pharyngeal neoplasm the diagnosis of meningioma, craniopharyngeoma and glioma should be considered as differential diagnosis to optimize the surgical procedure...
  24. pmc Radiation-induced leiomyosarcoma of the oropharynx
    Jens Pfeiffer
    Department of Otorhinolaryngology Head and Neck Surgery, Freiburg Medical School, Freiburg, Germany
    Diagn Pathol 1:22. 2006
    ..The highlights of this case are an extremely uncommon location and a rare pathological entity of radiation induced malignancies...
  25. pmc Juxtacondylar approach in temporal paraganglioma surgery: when and why?
    Joerg Schipper
    Department of Oto Rhino Laryngology, Head and Neck Surgery, University of Freiburg, Germany
    Skull Base 19:43-7. 2009
    ..In this article we demonstrate its use for the management of eight patients with locally advanced temporal PGLs and how it can be combined with an infratemporal fossa approach...
  26. ncbi request reprint Multifocal extranodal mucosa-associated lymphoid tissue lymphoma affecting the larynx
    Susan Arndt
    Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Freiburg, Germany
    Ann Otol Rhinol Laryngol 116:257-61. 2007
    ..Long-term localized growth is typical of MALT lymphoma. Multifocal manifestations are possible in advanced stages. MALT lymphoma of the larynx is a very rare disease; only 15 cases have been reported in the literature...
  27. doi request reprint Rhino-orbital-cerebral mucormycosis and aspergillosis: differential diagnosis and treatment
    Susan Arndt
    Department of Oto Rhino Laryngology, Head and Neck Surgery, University Medical Center Freiburg, Killianstrasse 5, 79106, Freiburg, Germany
    Eur Arch Otorhinolaryngol 266:71-6. 2009
    ..Radical procedures like orbital exenteration must be considered in all cases. The current state of diagnostics, therapy and prognosis is discussed based on these case reports and the recent literature...
  28. doi request reprint Radiologically assisted navigation in cochlear implantation for X-linked deafness malformation
    Antje Aschendorff
    Department of Otorhinolaryngology, University of Freiburg, Freiburg, Germany
    Cochlear Implants Int 10:14-8. 2009
    ..This approach enhances the precision of navigation and reduces the risk of improper electrode placement and additional surgery in complex malformations...
  29. pmc Clinical features of paraganglioma syndromes
    Carsten Christof Boedeker
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    Skull Base 19:17-25. 2009
    ..Mutation carriers must be screened for paraganglial tumors in the head, neck, thorax, and abdomen. Appropriately timed surgical intervention will minimize disease-specific morbidity and mortality. Lifelong follow-up is mandatory...
  30. ncbi request reprint Color duplex sonography for the monitoring of vascularized free bone flaps
    Ralf Schön
    Department of Oral and Maxillofacial Surgery, Albert Ludwigs Universitat
    Otolaryngol Head Neck Surg 129:71-6. 2003
    ..Study design Twelve free fibular bone flaps without a skin island were postoperatively monitored through color duplex sonography with a 7.5-MHz scanner...
  31. ncbi request reprint Giant-cell reparative granuloma of the temporal bone: a case report and review of the literature
    Carsten Christof Boedeker
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Killianstrasse 5, 79106 Freiburg, Germany
    Ear Nose Throat J 82:926-9, 933-4, 936-7. 2003
    ..We also review the cases of temporal bone GCRG that have been reported in the literature so far...
  32. ncbi request reprint Solitary neurofibroma of the maxillary sinus and pterygopalatine fossa
    Carsten Christof Boedeker
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Germany
    Otolaryngol Head Neck Surg 133:458-9. 2005
  33. ncbi request reprint [Ethisorb/Ethisorb durapatch for the transnasal duraplasty procedure?]
    S Arndt
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg, Killianstrasse 5, D 79106 Freiburg
    Laryngorhinootologie 85:260-4. 2006
    ..Defects of the dura in the rhinobasal area can be closed transnasally. Various procedures with autologous or alloplastic material can be chosen...
  34. ncbi request reprint [LED autoregistration in navigated endonasal sinus surgery]
    I Arapakis
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    Laryngorhinootologie 84:418-25. 2005
    ..With this new user-friendly system it concerns an active, LED-based, self-adhesive on the surface of splanchnocranium autoregistration mask...
  35. ncbi request reprint [Skull base chondrosarcoma. An interdisciplinary challenge]
    P U Lohnstein
    Klinik fur Hals, Nasen und Ohrenheilkunde, Universitätsklinikum Freiburg i Br
    HNO 54:287-93. 2006
    ..The prognosis was rated as unfavourable in articles for many years. It has, however, improved considerably in recent years. The objective of this study was to evaluate and current, new optimised treatment strategies...
  36. ncbi request reprint [Peritonsillar abscess: a life threatening disease--diagnostic and therapeutic aspects]
    S Kinzer
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    Laryngorhinootologie 86:371-5. 2007
    ..In those cases, oropharyngeal infection may lead to a descending process with consecutive mediastinitis as a life-threatening condition...
  37. ncbi request reprint [Craniofacial fibrous dysplasia: scan policy or surgery?]
    T D Dämmrich
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    Laryngorhinootologie 86:184-92. 2007
    ....
  38. ncbi request reprint [Evidence of a novel gene for the LAV-syndrome]
    R Birkenhäger
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg, Killianstrasse 5, D 79105 Freiburg
    Laryngorhinootologie 86:102-6. 2007
    ..This protein is expressed in the inner ear, thyroid gland, kidney, and placenta. Functional analysis of the gene product (pendrin) in Xenopus laevis oocytes revealed that pendrin acts as an iodide/chloride and chloride/formate exchanger...
  39. ncbi request reprint Rotational tomography of the normal and reconstructed middle ear in temporal bones: an experimental study
    Ch Offergeld
    Department of ORL, HNS, University of Freiburg, Freiburg, Germany
    Eur Arch Otorhinolaryngol 264:345-51. 2007
    ..The new imaging technique of RT allows precise presentation of anatomical structures and middle ear implants in temporal bones. Following these experimental results it will be our future work to evaluate this method in clinical practise...
  40. ncbi request reprint [Pseudodominants of two recessive connexin mutations in non-syndromic sensorineural hearing loss?]
    R Birkenhäger
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Forschungsgruppe Genetische Erkrankungen des Kopf Hals Bereiches, Universitatsklinikum Freiburg
    Laryngorhinootologie 85:191-6. 2006
    ..Each connexon is composed of six subunits, that allow communication between adjacent cells by providing a channel for diffusion of ions, metabolites and second messengers...
  41. ncbi request reprint [Etiology and therapy of the internal jugular vein thrombosis]
    C C Boedeker
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    Laryngorhinootologie 83:743-9. 2004
    ..Up to date, there is no standardized treatment regimen for patients with an IJVT...
  42. ncbi request reprint [Diagnosis and management of cervical paragangliomas: the Freiburg experience]
    C C Boedeker
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Freiburg
    Laryngorhinootologie 83:585-92. 2004
    ..They are highly vascular neoplasms that are benign in the majority of cases. There are controversial discussions concerning the different treatment options for cervical paragangliomas...
  43. ncbi request reprint [Objectivity of therapeutic results following skull base surgery using virtual model analysis]
    J Schipper
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    HNO 54:677-83. 2006
    ..The introduction of these models in clinical routine has been impaired by the extended time needed for the preparation of radiological data...
  44. doi request reprint [Malignant rhino- and otobasal mucosal melanomas--therapy and outcome]
    S Arndt
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde, Universitatsklinikum Freiburg, Killianstrasse 5, Freiburg
    Laryngorhinootologie 87:412-6. 2008
    ..Symptoms are unspecific in most cases, and patients often present with large tumours. During the past two decades, a variety of therapeutic modalities has been proposed...
  45. ncbi request reprint [The freiburg incision for cochlear implantation -- initial results]
    A Aschendorff
    Universitäts HNO Klinik Freiburg
    Laryngorhinootologie 84:408-11. 2005
    ..Recently newly developed types of incision are taken into account. In our experience over more than 15 years the extended endaural incision has proven to be reliable with a low complication rate...
  46. ncbi request reprint [The interesting case -- case no. 67]
    P U Lohnstein
    Universitäts HNO Klinik Freiburg
    Laryngorhinootologie 84:51-3. 2005
    ..It can grow to an enormous extent causing total obstruction of the upper respiratory tract. Until now its etiology is unknown. With a variety of differential diagnoses, a diagnostic concept is necessary...
  47. ncbi request reprint Working conditions on stage: climatic considerations
    B Richter
    Department of Phoniatrics and Pediatric Audiology, University of Freiburg, Germany
    Logoped Phoniatr Vocol 25:80-6. 2000
    ..Where unacceptable performance environments exist, special care should be taken to counsel performers with regard to possible prophylactic measures such as individual steam inhalation and fluid intake...
  48. doi request reprint [Carcinoid of the middle ear. A case report]
    E Rieh
    HNO Universitätsklinik Freiburg, Killianstrasse 5, 79106, Freiburg im Breisgau
    HNO 57:835-8. 2009
    ..Radiation therapy has not proved successful but the use of the somatostatin analog octreotide, interferon-alpha or palliative chemotherapy (e.g. streptozotosine, 5-fluorouracil) for metastases are further therapy options...
  49. ncbi request reprint Individual prefabricated titanium implants and titanium mesh in skull base reconstructive surgery. A report of cases
    J Schipper
    Department of Otorhinolaryngology and Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    Eur Arch Otorhinolaryngol 261:282-90. 2004
    ..As a disadvantage, CAD/CAM technology is more expensive than titanium mesh, and the process is time-consuming as it is carried out in advance of surgery...
  50. doi request reprint [Biomaterials in reconstructive skull base surgery]
    W Maier
    Universitäts Hals Nasen Ohren Klinik, Universitatsklinikum Freiburg, Freiburg
    Laryngorhinootologie 88:S64-75. 2009
    ..For extensive reconstructions of the orbita, titanium meshes and non-resorbable plastics have proven valuable, in closing smaller defects especially of the orbital floor, resorbable implants based on Polyglactin 901 are also used...
  51. doi request reprint Comparison of 3D C-arm-based registration to conventional pair-point registration regarding navigation accuracy in ENT surgery
    Tanja Daniela Grauvogel
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Ludwigs University, Medical School, Freiburg, Germany
    Otolaryngol Head Neck Surg 152:266-71. 2015
    ..The registration process is related to the main loss in accuracy. This study compared titanium screw registration with an inbuilt registration process of a 3-dimensional (3D) C-arm...
  52. doi request reprint Transmucosal core needle biopsy: a novel diagnostic approach to oral and oropharyngeal lesions
    Jens Pfeiffer
    Doctor, Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Freiburg, Germany Electronic address
    J Oral Maxillofac Surg 72:1594-600. 2014
    ..It has only previously been described in single cases and has not yet been separately discussed...
  53. pmc LOH-profiling by SNP-mapping in a case of multifocal head and neck cancer
    Jens Pfeiffer
    Jens Pfeiffer, Wolfgang Maier, Gerd J Ridder, Karim Zaoui, Ralf Birkenhäger, Department of Otorhinolaryngology, Head and Neck Surgery, University of Freiburg, 79106 Freiburg, Germany
    World J Clin Oncol 3:24-8. 2012
    ..To introduce an approach for the detection of putative genetic host factors that predispose patients to develop head and neck squamous cell carcinomas (HNSCC)...
  54. doi request reprint Influence of different registration modalities on navigation accuracy in ear, nose, and throat surgery depending on the surgical field
    Tanja D Grauvogel
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Ludwigs University, Killianstrasse 5, 79106 Freiburg, Germany
    Laryngoscope 120:881-8. 2010
    ..The present study compared the registration and navigation accuracy of three different registration modalities in anatomical locations of special interest for ear, nose, and throat surgery...
  55. doi request reprint Genetics of hereditary head and neck paragangliomas
    Carsten C Boedeker
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Ludwigs University, Freiburg, Germany
    Head Neck 36:907-16. 2014
    ..The purpose of this study was to give an overview on hereditary syndromes associated with head and neck paragangliomas (HNPGs)...
  56. ncbi request reprint Amyloid tumor of the larynx associated with plasma cell infiltration: differential diagnosis
    Susanne Benning
    Department of Otorhinolaryngology, Albert Ludwigs University Medical School, Freiburg, Germany
    Ear Nose Throat J 83:839-43. 2004
    ..We also discuss the available literature with respect to diagnostic and therapeutic procedures in patients with amyloidosis of the upper airway...
  57. ncbi request reprint Paragangliomas in patients with mutations of the SDHD gene
    Carsten Christof Boedeker
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Germany
    Otolaryngol Head Neck Surg 132:467-70. 2005
    ..We previously described a group of 271 pheochromocytoma patients, 11 of whom had mutations of the SDHD gene. The objective of this study was to find out whether those 11 patients had additional paragangliomas...
  58. ncbi request reprint Navigation as a tool to visualize bone-covered hidden structures in transfrontal approaches
    Joerg Schipper
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Freiburg Medical School, D 79106 Freiburg, Germany
    J Laryngol Otol 118:849-56. 2004
    ..Furthermore, the analysis indicated that under the guidance of a navigation system a precise pre-surgical simulation is available in order to perform an optimal craniotomy and reconstruction of the frontal skull base...
  59. ncbi request reprint A congenital teratoma with a cleft palate: report of a case
    S Becker
    Department of Oral, Maxillo and Craniofacial Surgery, Albert Ludwigs University Freiburg, Hugstetter Strasse 55, D 79106 Freiburg, Germany
    Br J Oral Maxillofac Surg 45:326-7. 2007
    ..On the day of birth debulking of the extraoral portion of the tumor, followed by intraoral exstirpation, was performed. The results of the histologic examination indicated a congenital epignathus. Six months later a recurrence was found...
  60. ncbi request reprint Concentration of cephalosporins in tissues of the head and neck after parenteral infusion
    W Maier
    Department of Oto Rhino Laryngology, University of Freiburg, Germany
    Chemotherapy 41:421-6. 1995
    ..The pharmacologic data show that both drugs are suitable for therapy and perioperative prophylaxis of purulent head and neck infections, but various data indicate that there is an advantage in favor of cefuroxime...
  61. doi request reprint [Cochlear implant for malformations of the inner ear]
    A Aschendorff
    HNO Klinik und Sektion Cochlear Implant, Universitat Freiburg, Freiburg, Germany
    HNO 57:533-41. 2009
    ..Rehabilitation results were generally very positive and corresponded to the expectation depending on the duration of deafness, if no additional handicaps were present...
  62. pmc Proliferation rate of human osteoblast-like cells on alloplastic biomaterials and their clinical application for the transnasal duraplasty procedure
    Susan Arndt
    Department of Oto Rhino Laryngology, Head and Neck Surgery, University of Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
    J Cell Mol Med 10:749-57. 2006
    ..The present study demonstrated an excellent biocompatibility of resorbable fleece. The vicryl fleece is an alternative alloplastic material for endonasal closure of defined substantial defects of the dura with cerebrospinal fluid...
  63. ncbi request reprint Recurrent syncope as presenting symptom of Burkitt's lymphoma at the carotid bifurcation
    Iakovos Arapakis
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    Ann Otol Rhinol Laryngol 113:373-7. 2004
    ..Repeated diagnostic testing and a coordination of multiple disciplines can speed diagnosis and therapeutic management. The current literature is reviewed and discussed...
  64. doi request reprint Descending necrotizing mediastinitis: contemporary trends in etiology, diagnosis, management, and outcome
    Gerd J Ridder
    Department of Otorhinolaryngology Head and Neck Surgery, University of Freiburg, Freiburg, Germany
    Ann Surg 251:528-34. 2010
    ..To evaluate contemporary trends in etiology, diagnosis, management, and outcome of descending necrotizing mediastinitis (DNM) and to draw the clinician's attention on this probably underappreciated disease...
  65. ncbi request reprint The free vastus lateralis flap for reconstruction in ablative oncologic head and neck surgery
    J Schipper
    Department of ORL H and N Surgery, Medical School, University of Freiburg, Killianstrasse 5, 79106 Freiburg, Germany
    Eur J Surg Oncol 32:103-7. 2006
    ..The vastus lateralis muscle is an accessory extensor for the knee suitable as a free myocutaneous flap in reconstructive head and neck surgery. We report the use of this muscle as a flap...
  66. ncbi request reprint [Endoscopic assisted endoluminal stapler-diverticulotomy of Zenker diverticulum]
    J Schipper
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg, Killianstrasse 5, D 79106 Freiburg, Germany
    Laryngorhinootologie 84:577-82. 2005
    ..The overview for the surgeon for correct placement of the clip device is limited due to the physiological narrowness of the pharyngeal tube...
  67. ncbi request reprint [Primary B-cell non-Hodgkin lymphoma of the internal auditory canal: case report and literature review]
    F B Knapp
    Universitäts HNO Klinik Freiburg, Killianstrasse 5, 79106, Freiburg
    HNO 56:633-7. 2008
    ..The course, diagnostics, and therapy of a rare case of primary B-cell NHL of the internal auditory canal are reported here...
  68. ncbi request reprint [Navigated "targeted surgery" for skull base malignomas: additional space for surgical manipulation by neoadjuvant tumor downsizing]
    J Schipper
    Universitätsklinik für HNO, Heinrich Heine Universitat Dusseldorf, Deutschland
    HNO 55:465-71. 2007
    ..As the incidence of these tumors is low, there are no evidence-based, generally accepted therapeutic strategies...
  69. ncbi request reprint [Paragangliomas in the head-/neck region. I: Classification and diagnosis]
    J Schipper
    Universitätsklinik für Hals Nasen Ohren Heilkunde und Poliklinik des Universitätsklinikum Freiburg
    HNO 52:569-74; quiz 575. 2004
    ..For diagnosis, an interdisciplinary, step by step procedure is mandatory comprising genetic screening, whole body medical check-up including catecholamine metabolism, and optionally an 18F-Dopa-PET and localised imaging procedures...
  70. ncbi request reprint [CAS in rhino-surgical procedures in the growing age]
    J Schipper
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    Laryngorhinootologie 84:13-9. 2005
    ..Computer assisted surgery (CAS) can help to identify these areas safely...
  71. ncbi request reprint [Computer-assisted surgery (CAS) for the optimal treatment of craniofacial fibrous dysplasia]
    J Schipper
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    HNO 53:766-72. 2005
    ..The rare bone disease craniofacial fibrous dysplasia is only treated in cases of visible deformities of the splanchnocranium and neurocranium, compression syndromes, and delocation of nasal and paranasal drainage...
  72. ncbi request reprint [Computer assisted methods in reconstructive and function-preserving orbital surgery. New capabilities of computer assisted preoperative surgical planning (CAPP) and computer assisted surgery (CAS)]
    C Zizelmann
    Arbeitsgruppe Interdisziplinäre rekonstruktive funktionserhaltende Orbitachirurgie, Universitatsklinikum Freiburg
    HNO 53:428-38. 2005
    ..Computer-assisted preoperative planning surgery (CAPP) and computer-assisted surgery (CAS) allow calculation of the form of the orbital cavity to be reconstructed preoperatively as well as the process of its realization intraoperatively...
  73. ncbi request reprint The human serotonin 7 (5-HT7) receptor gene: genomic organization and systematic mutation screening in schizophrenia and bipolar affective disorder
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Mol Psychiatry 1:392-7. 1996
    ..Our data suggests that genetic variation of the 5-HT7 receptor does not play a major role in the development of bipolar affective disorder and schizophrenia...
  74. ncbi request reprint [Characteristic findings in tumor of the endolymphatic sac]
    S Ziyeh
    Sektion Neuroradiologie, Neurozentrum, Universitatsklinikum Freiburg
    Rofo 176:1514-5. 2004
  75. ncbi request reprint [Paragangliomas of the head and neck. Part 2: Therapy and follow-up]
    J Schipper
    Universitätsklinik für Hals Nasen Ohren Heilkunde und Poliklinik des Universitätsklinikum Freiburg
    HNO 52:651-60; quiz 661. 2004
    ..Glomus caroticum tumors are resected transcervically. In cases of contraindications for surgery or in palliative situations radiotherapy is recommended...
  76. ncbi request reprint Exonic variants of the GABA(B) receptor gene and panic disorder
    P G Sand
    Department of Psychiatry, University of Wurzburg, Germany
    Psychiatr Genet 10:191-4. 2000
    ..There was no indication of an increased vulnerability to panic disorder or agoraphobia with respect to the allelic variants under study...
  77. ncbi request reprint [Does computer-aided navigation of endonasal sinus surgery improve process quality and outcome quality?]
    J Schipper
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    Laryngorhinootologie 83:298-307. 2004
    ..In this respect, factors of investment costs and additional costs for time exposure will be discussed as well...
  78. ncbi request reprint [Neurophysiologic intraoperative monitoring to preserve cranial nerve function in base of skull surgery]
    J Schipper
    Interdisziplinäres Zentrum für Schädelbasis und Craniofaciale Chirurgie am Universitätsklinikum Freiburg
    HNO 52:897-907. 2004
    ..Currently, both motor and sensory cranial nerves, including the IInd and VIIIth cranial nerves, can be intraoperatively controlled by means of small and mobile systems...
  79. ncbi request reprint [Information assisted surgery as a transdisciplinary surgical procedure]
    J Schipper
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    Laryngorhinootologie 84:165-70. 2005
    ..The advantage of IAS is the predictability of the surgical procedure according to the specifications of modern quality assessment...
  80. ncbi request reprint Identification of two novel polymorphisms and a rare deletion variant in the human dopamine D4 receptor gene
    S Cichon
    Institute of Human Genetics, University of Bonn, Germany
    Psychiatr Genet 5:97-103. 1995
    ..We were unable to detect the deletion in patients with schizophrenia and bipolar affective disorder, nor in healthy controls...
  81. ncbi request reprint Evidence for association of DNA sequence variants in the phosphatidylinositol-4-phosphate 5-kinase IIalpha gene (PIP5K2A) with schizophrenia
    S G Schwab
    Western Australian Institute of Medical Research and Center for Medical Research, University of Western Australia, Perth, WA, Australia
    Mol Psychiatry 11:837-46. 2006
    ..PI(4,5)P2 plays a role in membrane transduction of neurotransmitter signals as well as in intracellular signalling, pathways that may be impaired in schizophrenia...
  82. ncbi request reprint [Reconstruction of tumor induced defects in head and neck surgery with individualized prefabricated three dimensional flaps with the use of continuous vacuum therapy]
    J Schipper
    Universitäts HNO Klinik Freiburg
    Zentralbl Chir 131:S141-5. 2006
    ..This article describes the technique of vacuum therapy for the pre-fabrication of three-dimensional pedicled or free flaps for reconstruction of defects after tumor resection in the head and neck area...
  83. ncbi request reprint [Tumour staged surgery of endolymphatic sac tumors (ELST)]
    J Schipper
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    Laryngorhinootologie 83:493-500. 2004
    ..This connection has been observed in 1992 for the first time and confirmed by molecular genetic analyses of the VHL gen. There is no agreement yet concerning diagnostics and therapy...
  84. pmc Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: supportive evidence for linkage at 3p14
    B Etain
    INSERM U513, Neurobiology and Psychiatry, Faculte de Medecine, Creteil, France
    Mol Psychiatry 11:685-94. 2006
    ..51 to 3.83. This study is the first to use early-onset bipolar type I probands in an attempt to increase sample homogeneity. These preliminary findings require confirmation in independent panels of families...
  85. ncbi request reprint Evolution of percutaneous transluminal coronary angioplasty in Europe from 1992-1996
    W Maier
    Cardiology, Swiss Cardiovascular Bern, Bern, Switzerland
    Eur Heart J 22:1733-40. 2001
    ..CONCLUSIONS: An overall increase in PTCAs at an annual rate between 15 and 25% was observed. The wide variation in the use of PTCA in Europe appears to be dependent mostly on economic factors and national health care policies...
  86. ncbi request reprint [Guided surgery in a subtemporal approach in CPA tumors?]
    J Schipper
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg
    Laryngorhinootologie 84:809-16. 2005
    ..The surgeon might be able to orientate anatomically during surgery without having to prepare the according landmarks. This would mean less surgical traumatization and a shorter and smaller operation corridor...
  87. ncbi request reprint Genetic investigation of chromosome 5q GABAA receptor subunit genes in schizophrenia
    T L Petryshen
    Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA
    Mol Psychiatry 10:1074-88, 1057. 2005
    ..Taken together, these results support the involvement of the chromosome 5q GABAA receptor gene cluster in schizophrenia, and suggest that schizophrenia-associated haplotypes may alter expression of GABA-related genes...
  88. ncbi request reprint Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: identification of two naturally occurring receptor variants and association analysis in schizophrenia
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Hum Genet 97:614-9. 1996
    ..However, the reported association of the non-coding polymorphism 102T/C with the disease has also been detected in our sample (P=0.041, odds ratio=1.28, 95% confidence interval 1.012-1.623)...
  89. ncbi request reprint Human nuclear transcription factor gene CREM: genomic organization, mutation screening, and association analysis in panic disorder
    K Domschke
    Department of Psychiatry, University of Munster, Munster, Germany
    Am J Med Genet B Neuropsychiatr Genet 117:70-8. 2003
    ..Functional analysis of the observed CREM P 2 promoter polymorphism as well as studies in independent panic disorder samples are necessary...
  90. ncbi request reprint Analysis of a polymorphism in the tuberous sclerosis (TSC2) gene does not predispose to schizophrenia
    R Przkora
    Department of Neuropathology, University of Bonn Medical Center, Germany
    Eur Arch Psychiatry Clin Neurosci 248:314-5. 1998
    ..A 222-bp fragment of genomic DNA containing the TSC2 variant was analyzed by SSCP. The analysis revealed that there is no association with schizophrenia...
  91. ncbi request reprint Serotonin receptor gene HTR3A variants in schizophrenic and bipolar affective patients
    B Niesler
    Institute of Human Genetics, University of Heidelberg, Germany
    Pharmacogenetics 11:21-7. 2001
    ..Further studies are needed to support the hypothesis that HTR3A may contribute to the schizophrenia in these patients...
  92. ncbi request reprint The impact of gender and age at onset on the familial aggregation of schizophrenia
    W Maier
    Department of Psychiatry, University of Mainz, Germany
    Eur Arch Psychiatry Clin Neurosci 242:279-85. 1993
    ..Affective disorders occurred in families independently of the probands' gender. Aetiological heterogeneity or ascertainment bias may account for the modifying effect of proband's gender in schizophrenia...
  93. ncbi request reprint No evidence for linkage by transmission disequilibrium test analysis of microsatellite marker D22S278 and schizophrenia in a Palestinian Arab and in a German population
    M Dobrusin
    Beersheva Mental Health Center, Beersheva, Israel
    Am J Med Genet 105:328-31. 2001
    ..11, P = 0.12, df = 9; Beersheva: chi-square = 7.04, P = 0.32, df = 6). Additionally, we examined D22S278 in a group of 114 schizophrenic German triads and failed to observe evidence for linkage (chi-square = 8.13, P = 0.42, df = 8df)...
  94. ncbi request reprint Nonreplication of association between mu-opioid-receptor gene (OPRM1) A118G polymorphism and substance dependence
    P Franke
    Department of Psychiatry University of Bonn, Germany
    Am J Med Genet 105:114-9. 2001
    ..In addition, there was no significant association between the endophenotype of the individuals under study (e.g., comorbidity, severity of illness) and a particular genotype of OPRM1...
  95. ncbi request reprint Polymorphism in the peroxisome proliferator-activated receptor alpha gene influences the risk for Alzheimer's disease
    S Brune
    Department of Psychiatry, University of Bonn, Germany
    J Neural Transm (Vienna) 110:1041-50. 2003
    ..Cerebrospinal fluid amyloid-beta levels were influenced by PPAR-alpha L162V genotype. These results suggest, that PPAR-alpha polymorphism may be a risk factor for AD...
  96. ncbi request reprint Impulsiveness in obsessive-compulsive disorder: results from a family study
    S Ettelt
    Department of Psychiatry and Psychotherapy, University of Greifswald, Stralsund, Germany
    Acta Psychiatr Scand 115:41-7. 2007
    ..The purpose of this study was to assess impulsiveness in OCD families and compare it to control families...
  97. pmc Support for the association between the rare functional variant I425V of the serotonin transporter gene and susceptibility to obsessive compulsive disorder
    R Delorme
    Mol Psychiatry 10:1059-61. 2005
  98. ncbi request reprint Transmission disequilibrium and haplotype analyses of the G72/G30 locus: suggestive linkage to schizophrenia in Palestinian Arabs living in the North of Israel
    M Korostishevsky
    Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel 69978
    Am J Med Genet B Neuropsychiatr Genet 141:91-5. 2006
    ..These data suggest a common risk factor for schizophrenia susceptibility in the G72/G30 locus among Ashkenazi Jews and Palestinian Arabs. The results strengthen previous reports on the role of this locus in the etiology of schizophrenia...
  99. ncbi request reprint A family-based and case-control association study of trace amine receptor genes on chromosome 6q23 in bipolar affective disorder
    R Abou Jamra
    Mol Psychiatry 10:618-20. 2005
  100. ncbi request reprint [Subtemporal approach according to house versus Wigand in intrameatal CPA tumors type A]
    J Schipper
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde und Poliklinik, Universitatsklinikum Freiburg, Freiburg
    Laryngorhinootologie 83:647-52. 2004
    ....
  101. ncbi request reprint The risk of minor depression in families of probands with major depression: sex differences and familiality
    W Maier
    Department of Psychiatry, University of Mainz, Federal Republic of Germany
    Eur Arch Psychiatry Clin Neurosci 242:89-92. 1992
    ..The variation of the sex ratio for any subtype of unipolar depression was not associated with the familiality of this disorder...