Mathias H Konstandin

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi request reprint A sensitive assay for the quantification of integrin-mediated adhesiveness of human stem cells and leukocyte subpopulations in whole blood
    Mathias H Konstandin
    Department of Cardiology, Internal Medicine, Ruprecht Karls University, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    J Immunol Methods 327:30-9. 2007
  2. ncbi request reprint Pharmacodynamic cyclosporine A-monitoring: relation of gene expression in lymphocytes to cyclosporine blood levels in cardiac allograft recipients
    Mathias H Konstandin
    Department of Cardiology, Internal Medicine, Ruprecht Karls University, Heidelberg, Germany
    Transpl Int 20:1036-43. 2007
  3. doi request reprint Ezetimibe effectively lowers LDL-cholesterol in cardiac allograft recipients on stable statin therapy
    Mathias H Konstandin
    Department of Cardiology, Internal Medicine, Ruprecht Karls University, Heidelberg, Germany
    Clin Transplant 22:639-44. 2008
  4. doi request reprint Beta2-integrin activation on T cell subsets is an independent prognostic factor in unstable angina pectoris
    Mathias H Konstandin
    Dept of Cardiology, Ruprecht Karls University, Heidelberg, Germany
    Basic Res Cardiol 104:341-51. 2009
  5. doi request reprint Severe right ventricular outflow tract obstruction caused by non-hodgkin lymphoma: complete regression after one course of bendamustine/rituximab therapy
    Mathias H Konstandin
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    J Am Soc Echocardiogr 24:818.e1-4. 2011
  6. ncbi request reprint High affinity interaction of integrin alpha4beta1 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) enhances migration of human melanoma cells across activated endothelial cell layers
    Martin Klemke
    Institute for Immunology, University of Heidelberg, Heidelberg, Germany
    J Cell Physiol 212:368-74. 2007
  7. pmc An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments
    Martin Klemke
    Institute for Immunology, University of Heidelberg, Heidelberg, Germany
    EMBO J 29:2915-29. 2010
  8. ncbi request reprint Costimulation induced phosphorylation of L-plastin facilitates surface transport of the T cell activation molecules CD69 and CD25
    Guido H Wabnitz
    Institute for Immunology, Ruprecht Karls University, Heidelberg, Germany
    Eur J Immunol 37:649-62. 2007
  9. ncbi request reprint Phosphorylation of ectopically expressed L-plastin enhances invasiveness of human melanoma cells
    Martin Klemke
    Department of Immunology and Serology, University of Heidelberg, D 69120 Heidelberg, Germany
    Int J Cancer 120:2590-9. 2007

Detail Information

Publications9

  1. ncbi request reprint A sensitive assay for the quantification of integrin-mediated adhesiveness of human stem cells and leukocyte subpopulations in whole blood
    Mathias H Konstandin
    Department of Cardiology, Internal Medicine, Ruprecht Karls University, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    J Immunol Methods 327:30-9. 2007
    ..Finally, the small blood volumes needed for adhesion analysis with the LC-AA allow the evaluation of multiple cell subpopulations in large sample collectives, e.g. required in clinical studies...
  2. ncbi request reprint Pharmacodynamic cyclosporine A-monitoring: relation of gene expression in lymphocytes to cyclosporine blood levels in cardiac allograft recipients
    Mathias H Konstandin
    Department of Cardiology, Internal Medicine, Ruprecht Karls University, Heidelberg, Germany
    Transpl Int 20:1036-43. 2007
    ..It correlates better with the incidence of infections than measurement of CsA concentrations and might help in avoiding over-immunosuppression...
  3. doi request reprint Ezetimibe effectively lowers LDL-cholesterol in cardiac allograft recipients on stable statin therapy
    Mathias H Konstandin
    Department of Cardiology, Internal Medicine, Ruprecht Karls University, Heidelberg, Germany
    Clin Transplant 22:639-44. 2008
    ..Extent of pre-treatment LDL-C and cardiac disorder prior to transplantation appear to correlate with the efficacy of ezetimibe therapy...
  4. doi request reprint Beta2-integrin activation on T cell subsets is an independent prognostic factor in unstable angina pectoris
    Mathias H Konstandin
    Dept of Cardiology, Ruprecht Karls University, Heidelberg, Germany
    Basic Res Cardiol 104:341-51. 2009
    ..Beta2-integrin mediated T cell recruitment plays a pivotal role in coronary atherosclerotic plaque rupture. The present study investigates beta2-integrin activation on T cell subsets as a risk marker in UA...
  5. doi request reprint Severe right ventricular outflow tract obstruction caused by non-hodgkin lymphoma: complete regression after one course of bendamustine/rituximab therapy
    Mathias H Konstandin
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    J Am Soc Echocardiogr 24:818.e1-4. 2011
    ..Compression of the heart and great vessels, such as by mediastinal tumors, is not as rare. Prompt and accurate diagnosis by echocardiography and immediate initiation of treatment can be lifesaving...
  6. ncbi request reprint High affinity interaction of integrin alpha4beta1 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) enhances migration of human melanoma cells across activated endothelial cell layers
    Martin Klemke
    Institute for Immunology, University of Heidelberg, Heidelberg, Germany
    J Cell Physiol 212:368-74. 2007
    ..These data imply that only high affinity interactions between the integrin alpha4beta1 on melanoma cells and VCAM-1 on activated endothelial cells may enhance the metastatic capacity of human beta2/beta3-negative melanoma cells...
  7. pmc An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments
    Martin Klemke
    Institute for Immunology, University of Heidelberg, Heidelberg, Germany
    EMBO J 29:2915-29. 2010
    ..This MEK-cofilin module may have an important function in the tissue positioning of T cells during an immune response...
  8. ncbi request reprint Costimulation induced phosphorylation of L-plastin facilitates surface transport of the T cell activation molecules CD69 and CD25
    Guido H Wabnitz
    Institute for Immunology, Ruprecht Karls University, Heidelberg, Germany
    Eur J Immunol 37:649-62. 2007
    ..In conclusion, phosphorylation of the actin bundling protein L-plastin represents a so-far-unknown mechanism by which costimulation controls the transport of activation receptors to the T cell surface...
  9. ncbi request reprint Phosphorylation of ectopically expressed L-plastin enhances invasiveness of human melanoma cells
    Martin Klemke
    Department of Immunology and Serology, University of Heidelberg, D 69120 Heidelberg, Germany
    Int J Cancer 120:2590-9. 2007
    ..These data show that an increase in melanoma cell invasiveness requires not only expression but also phosphorylation of L-plastin...