Mihail Hristov

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint Endothelial progenitor cells: mobilization, differentiation, and homing
    Mihail Hristov
    Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten, Ludwig Maximilians Universitat, Pettenkoferstr 9, 80336 Munchen, Germany
    Arterioscler Thromb Vasc Biol 23:1185-9. 2003
  2. ncbi request reprint Endothelial progenitor cells: isolation and characterization
    Mihail Hristov
    Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten, Ludwig Maximilians Universitat Munchen, Pettenkoferstrasse 9, 80336 Munich, Germany
    Trends Cardiovasc Med 13:201-6. 2003
  3. ncbi request reprint Apoptotic bodies from endothelial cells enhance the number and initiate the differentiation of human endothelial progenitor cells in vitro
    Mihail Hristov
    Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten, Ludwig Maximilians Universitat, Munchen, Germany
    Blood 104:2761-6. 2004
  4. doi request reprint High-reproducible flow cytometric endothelial progenitor cell determination in human peripheral blood as CD34+/CD144+/CD3- lymphocyte sub-population
    Santiago Redondo
    Department of Pharmacology, School of Medicine, Universidad Complutense, Madrid, Spain
    J Immunol Methods 335:21-7. 2008
  5. ncbi request reprint HMG-CoA reductase inhibitors induce apoptosis in neointima-derived vascular smooth muscle cells
    Wolfgang Erl
    Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten, Ludwig Maximilians Universitat Munchen, Pettenkoferstr 9, München 80336, Germany
    Atherosclerosis 169:251-8. 2003
  6. ncbi request reprint Regulation of endothelial progenitor cell homing after arterial injury
    Mihail Hristov
    Institute for Molecular Cardiovascular Research IMCAR, Aachen, Germany
    Thromb Haemost 98:274-7. 2007
  7. ncbi request reprint Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice
    Ela Karshovska
    Division of Cardiology, Medizinische Poliklinik, University of Munich, Pettenkoferstrasse 8a, 80336 Munich, Germany
    Arterioscler Thromb Vasc Biol 27:2540-7. 2007
  8. ncbi request reprint Transplantation of endothelial progenitor cells improves neovascularization and left ventricular function after myocardial infarction in a rat model
    Alexander Schuh
    IZKF BIOMAT, Aachen, Germany
    Basic Res Cardiol 103:69-77. 2008
  9. ncbi request reprint C1-esterase inhibitor protects against neointima formation after arterial injury in atherosclerosis-prone mice
    Erdenechimeg Shagdarsuren
    Institute of Molecular Cardiovascular Research, University Hospital, RWTH Aachen University, Aachen, Germany
    Circulation 117:70-8. 2008
  10. ncbi request reprint Biphasic effect of pioglitazone on isolated human endothelial progenitor cells: involvement of peroxisome proliferator-activated receptor-gamma and transforming growth factor-beta1
    Santiago Redondo
    Department of Pharmacology, School of Medicine, Universidad Complutense, Madrid, Spain
    Thromb Haemost 97:979-87. 2007

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Endothelial progenitor cells: mobilization, differentiation, and homing
    Mihail Hristov
    Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten, Ludwig Maximilians Universitat, Pettenkoferstr 9, 80336 Munchen, Germany
    Arterioscler Thromb Vasc Biol 23:1185-9. 2003
    ..Thus, future studies will help to explore areas of potential basic research and clinical application of EPCs...
  2. ncbi request reprint Endothelial progenitor cells: isolation and characterization
    Mihail Hristov
    Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten, Ludwig Maximilians Universitat Munchen, Pettenkoferstrasse 9, 80336 Munich, Germany
    Trends Cardiovasc Med 13:201-6. 2003
    ....
  3. ncbi request reprint Apoptotic bodies from endothelial cells enhance the number and initiate the differentiation of human endothelial progenitor cells in vitro
    Mihail Hristov
    Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten, Ludwig Maximilians Universitat, Munchen, Germany
    Blood 104:2761-6. 2004
    ..Such a mechanism may facilitate the repair of injured endothelium and may represent a new signaling pathway between progenitor and damaged somatic cells...
  4. doi request reprint High-reproducible flow cytometric endothelial progenitor cell determination in human peripheral blood as CD34+/CD144+/CD3- lymphocyte sub-population
    Santiago Redondo
    Department of Pharmacology, School of Medicine, Universidad Complutense, Madrid, Spain
    J Immunol Methods 335:21-7. 2008
    ..8517 to 0.8908. Therefore, the technical setting described here offers a high-performance and clinically oriented EPC determination strategy in human peripheral blood...
  5. ncbi request reprint HMG-CoA reductase inhibitors induce apoptosis in neointima-derived vascular smooth muscle cells
    Wolfgang Erl
    Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten, Ludwig Maximilians Universitat Munchen, Pettenkoferstr 9, München 80336, Germany
    Atherosclerosis 169:251-8. 2003
    ..Our results suggest that statins enhance the rate of apoptosis in neointimal SMC, which may be an interesting feature to reduce restenosis after successful angioplasty...
  6. ncbi request reprint Regulation of endothelial progenitor cell homing after arterial injury
    Mihail Hristov
    Institute for Molecular Cardiovascular Research IMCAR, Aachen, Germany
    Thromb Haemost 98:274-7. 2007
    ....
  7. ncbi request reprint Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice
    Ela Karshovska
    Division of Cardiology, Medizinische Poliklinik, University of Munich, Pettenkoferstrasse 8a, 80336 Munich, Germany
    Arterioscler Thromb Vasc Biol 27:2540-7. 2007
    ..Because HIF-1alpha can be activated under normoxic conditions in smooth muscle cells (SMCs) by platelet products, we investigated the role of HIF-1alpha in SDF-1alpha-mediated neointima formation after vascular injury...
  8. ncbi request reprint Transplantation of endothelial progenitor cells improves neovascularization and left ventricular function after myocardial infarction in a rat model
    Alexander Schuh
    IZKF BIOMAT, Aachen, Germany
    Basic Res Cardiol 103:69-77. 2008
    ..These results imply a combined benefit of EPCs+SDF-1alpha in the treatment of myocardial infarction...
  9. ncbi request reprint C1-esterase inhibitor protects against neointima formation after arterial injury in atherosclerosis-prone mice
    Erdenechimeg Shagdarsuren
    Institute of Molecular Cardiovascular Research, University Hospital, RWTH Aachen University, Aachen, Germany
    Circulation 117:70-8. 2008
    ..Here, we examined the contribution of the complement cascade to neointima formation in apolipoprotein E-deficient mice using a C1-esterase inhibitor (C1-inhibitor)...
  10. ncbi request reprint Biphasic effect of pioglitazone on isolated human endothelial progenitor cells: involvement of peroxisome proliferator-activated receptor-gamma and transforming growth factor-beta1
    Santiago Redondo
    Department of Pharmacology, School of Medicine, Universidad Complutense, Madrid, Spain
    Thromb Haemost 97:979-87. 2007
    ..These results may help to define optimal therapeutic doses of pioglitazone for improving endothelial dysfunction...
  11. ncbi request reprint Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury
    Mihail Hristov
    Institut für Kardiovaskuläre Molekularbiologie, Universitatsklinikum Aachen, Pauwelsstr 30, 52074 Aachen, Germany
    Circ Res 100:590-7. 2007
    ..In conclusion, our data clearly demonstrate the importance of CXCR2 for the homing of circulating EPCs to sites of arterial injury and for endothelial recovery in vivo...
  12. ncbi request reprint Reduced numbers of circulating endothelial progenitor cells in patients with coronary artery disease associated with long-term statin treatment
    Mihail Hristov
    Institute for Molecular Cardiovascular Research, RWTH Aachen University, University Hospital Aachen, Aachen, Germany
    Atherosclerosis 192:413-20. 2007
    ..Thus, the statin dose during chronic and continuous treatment independently predicts reduced numbers of circulating as well as isolated EPCs in patients with CAD...
  13. ncbi request reprint [The therapeutic effect of autologous bone marrow cells in ischemic heart disease]
    Mihail Hristov
    Kardiovaskuläre Molekularbiologie, Universitätsklinikum der RWTH Aachen
    Med Klin (Munich) 101:186-9. 2006
    ..Hence, larger case-controlled, randomized and double-blinded trials in addition to experimental investigations on the primary molecular mechanisms of myocardial repair are crucial for the future...
  14. ncbi request reprint A novel drug-eluting stent coated with an integrin-binding cyclic Arg-Gly-Asp peptide inhibits neointimal hyperplasia by recruiting endothelial progenitor cells
    Rüdiger Blindt
    Department of Cardiology, University Hospital Aachen, Aachen, Germany
    J Am Coll Cardiol 47:1786-95. 2006
    ..Novel stents loaded with an integrin-binding cyclic Arg-Gly-Asp peptide (cRGD) were analyzed for their potential to limit coronary neointima formation and to accelerate endothelialization by attracting endothelial progenitor cells (EPCs)...
  15. ncbi request reprint Endothelial progenitor cells: characterization, pathophysiology, and possible clinical relevance
    Mihail Hristov
    Department for Molecular Cardiovascular Research, University Hospital Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
    J Cell Mol Med 8:498-508. 2004
    ..However, the specificity of the observed positive clinical effects, the mechanisms regulating the differentiation of EPCs and their homing to sites of injured tissue remain partially unknown at present...
  16. ncbi request reprint The therapeutic potential of progenitor cells in ischemic heart disease--Past, present and future
    Mihail Hristov
    Basic Res Cardiol 101:1-7. 2006
    ..Hence, larger controlled randomized and double-blinded trials in addition to experimental investigations on the primary mechanisms of repair are keenly anticipated...
  17. doi request reprint Adult progenitor cells in vascular remodeling during atherosclerosis
    Mihail Hristov
    Institut für Molekulare Herz Kreislaufforschung, Universitätsklinikum der RWTH Aachen, Pauwelsstrasse 30, Aachen, Germany
    Biol Chem 389:837-44. 2008
    ....