Claudia Hofmann

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. doi request reprint Glycogen synthase kinase 3-β: a master regulator of toll-like receptor-mediated chronic intestinal inflammation
    Claudia Hofmann
    Department of Internal Medicine I, Regensburg University Medical Center, Germany
    Inflamm Bowel Dis 16:1850-8. 2010
  2. doi request reprint C1q/TNF-related protein-3 (CTRP-3) is secreted by visceral adipose tissue and exerts antiinflammatory and antifibrotic effects in primary human colonic fibroblasts
    Claudia Hofmann
    Department of Internal Medicine I, University Medical Center Regensburg, Germany
    Inflamm Bowel Dis 17:2462-71. 2011
  3. doi request reprint T cell-dependent protective effects of CpG motifs of bacterial DNA in experimental colitis are mediated by CD11c+ dendritic cells
    Claudia Hofmann
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Gut 59:1347-54. 2010
  4. doi request reprint Primary human colonic epithelial cells are transiently protected from anoikis by a Src-dependent mechanism
    Claudia Hofmann
    Department of Internal Medicine I, Regensburg University Medical Center, 93042 Regensburg, Germany
    Biochem Biophys Res Commun 390:908-14. 2009
  5. doi request reprint Physiologic TLR9-CpG-DNA interaction is essential for the homeostasis of the intestinal immune system
    Claudia Hofmann
    Departments of Internal Medicine I, and Internal Medicine III, Regensburg University Medical Center, Regensburg, Germany
    Inflamm Bowel Dis 20:136-43. 2014
  6. doi request reprint IL-33 attenuates development and perpetuation of chronic intestinal inflammation
    Philipp Groβ
    Department of Internal Medicine I, University Hospital Regensburg, Germany
    Inflamm Bowel Dis 18:1900-9. 2012
  7. doi request reprint Bilberries and their anthocyanins ameliorate experimental colitis
    Heidi Piberger
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Mol Nutr Food Res 55:1724-9. 2011
  8. ncbi request reprint Cell-cell contacts prevent anoikis in primary human colonic epithelial cells
    Claudia Hofmann
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Gastroenterology 132:587-600. 2007
  9. ncbi request reprint CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation
    Florian Obermeier
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Gastroenterology 129:913-27. 2005
  10. doi request reprint Mucosal immunosuppression and epithelial barrier defects are key events in murine psychosocial stress-induced colitis
    Stefan O Reber
    Department of Behavioral and Molecular Neuroendocrinology, Neuroscience Centre, University of Regensburg, 93053 Regensburg, Germany
    Brain Behav Immun 25:1153-61. 2011

Collaborators

Detail Information

Publications14

  1. doi request reprint Glycogen synthase kinase 3-β: a master regulator of toll-like receptor-mediated chronic intestinal inflammation
    Claudia Hofmann
    Department of Internal Medicine I, Regensburg University Medical Center, Germany
    Inflamm Bowel Dis 16:1850-8. 2010
    ..The aim of this study was to assess the role of GSK3-β activity in chronic intestinal inflammation...
  2. doi request reprint C1q/TNF-related protein-3 (CTRP-3) is secreted by visceral adipose tissue and exerts antiinflammatory and antifibrotic effects in primary human colonic fibroblasts
    Claudia Hofmann
    Department of Internal Medicine I, University Medical Center Regensburg, Germany
    Inflamm Bowel Dis 17:2462-71. 2011
    ..The aim was to investigate the antiinflammatory and antifibrotic role of CTRP-3 in Crohn's disease (CD)...
  3. doi request reprint T cell-dependent protective effects of CpG motifs of bacterial DNA in experimental colitis are mediated by CD11c+ dendritic cells
    Claudia Hofmann
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Gut 59:1347-54. 2010
    ..Administration of CpG-ODNs before the onset of experimental colitis prevents intestinal inflammation by induction of colitis-suppressing T cells...
  4. doi request reprint Primary human colonic epithelial cells are transiently protected from anoikis by a Src-dependent mechanism
    Claudia Hofmann
    Department of Internal Medicine I, Regensburg University Medical Center, 93042 Regensburg, Germany
    Biochem Biophys Res Commun 390:908-14. 2009
    ..Src is an important mediator of this mechanism and therefore constitutes a key regulatory molecule coordinating survival signals mediated by cell adhesion in primary human CEC...
  5. doi request reprint Physiologic TLR9-CpG-DNA interaction is essential for the homeostasis of the intestinal immune system
    Claudia Hofmann
    Departments of Internal Medicine I, and Internal Medicine III, Regensburg University Medical Center, Regensburg, Germany
    Inflamm Bowel Dis 20:136-43. 2014
    ..It was investigated whether physiologic CpG/TLR9 interactions are critical for the homeostasis of the intestinal immune system...
  6. doi request reprint IL-33 attenuates development and perpetuation of chronic intestinal inflammation
    Philipp Groβ
    Department of Internal Medicine I, University Hospital Regensburg, Germany
    Inflamm Bowel Dis 18:1900-9. 2012
    ....
  7. doi request reprint Bilberries and their anthocyanins ameliorate experimental colitis
    Heidi Piberger
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Mol Nutr Food Res 55:1724-9. 2011
    ..Oral administration of ACs resulted in an amelioration of acute colitis as well as chronic colitis. These promising results justify a clinical study on their therapeutic effect in inflammatory bowel disease patients...
  8. ncbi request reprint Cell-cell contacts prevent anoikis in primary human colonic epithelial cells
    Claudia Hofmann
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Gastroenterology 132:587-600. 2007
    ..In contrast to the established role of cell-matrix contact, the role of cell-cell contacts as a physiologic survival factor for CECs is less clear...
  9. ncbi request reprint CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation
    Florian Obermeier
    Department of Internal Medicine I, University of Regensburg, Regensburg, Germany
    Gastroenterology 129:913-27. 2005
    ..Here, we investigated whether DNA derived from luminal bacteria plays a role in the perpetuation of chronic intestinal inflammation...
  10. doi request reprint Mucosal immunosuppression and epithelial barrier defects are key events in murine psychosocial stress-induced colitis
    Stefan O Reber
    Department of Behavioral and Molecular Neuroendocrinology, Neuroscience Centre, University of Regensburg, 93053 Regensburg, Germany
    Brain Behav Immun 25:1153-61. 2011
    ..However, aggravation by the immune-modulatory effects of fluctuating levels of adrenal hormones is required to develop this into a full-blown colitis...
  11. doi request reprint DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH
    Erwin Gabele
    Department of Internal Medicine I, University Medical Center Regensburg, Germany
    J Hepatol 55:1391-9. 2011
    ..Application of dextran sulfate sodium (DSS) is a colitis model in mice characterized by damage of the intestinal barrier. This study was designed to investigate if application of DSS aggravates experimental NASH...
  12. pmc Lipid alterations in experimental murine colitis: role of ceramide and imipramine for matrix metalloproteinase-1 expression
    Jessica Bauer
    Department of Internal Medicine I, University Medical Center, Regensburg, Germany
    PLoS ONE 4:e7197. 2009
    ..Therefore, we analysed alterations of bioactive lipids in experimental models of colitis and examined the functional consequence of the second messenger ceramide in inflammatory pathways leading to tissue destruction...
  13. pmc Inflammatory bowel diseases: when natural friends turn into enemies-the importance of CpG motifs of bacterial DNA in intestinal homeostasis and chronic intestinal inflammation
    Florian Obermeier
    Department of Internal Medicine I, University of Regensburg, 93042 Regensburg, Germany
    Int J Inflam 2010:641910. 2010
    ..In this review we suggest that regulators of TLR signaling may be interesting therapeutic targets in IBD aiming at the restoration of intestinal immune homeostasis...
  14. ncbi request reprint RNA expression profiling of normal and tumor cells following photodynamic therapy with 5-aminolevulinic acid-induced protoporphyrin IX in vitro
    Peter J Wild
    Institute of Pathology, University of Regensburg, Regensburg, Germany
    Mol Cancer Ther 4:516-28. 2005
    ..RNA expression profiling of normal and tumor cell lines following photodynamic therapy with 5-aminolevulinic acid gave insight into the major molecular mechanisms induced by photodynamic therapy...