T Hillemacher

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. ncbi request reprint Neurobiology and treatment in alcoholism--recent findings regarding Lesch's typology of alcohol dependence
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 43:341-6. 2008
  2. ncbi request reprint Alteration of prolactin serum levels during alcohol withdrawal correlates with craving in female patients
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Addict Biol 10:337-43. 2005
  3. ncbi request reprint Recurrent detoxifications are associated with craving in patients classified as type 1 according to Lesch's typology
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 41:66-9. 2006
  4. ncbi request reprint Influence of beer, wine and spirits consumption on craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Addict Biol 10:181-6. 2005
  5. ncbi request reprint Plasma homocysteine concentrations do not influence craving in alcohol withdrawal
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol 34:211-5. 2004
  6. ncbi request reprint Elevated prolactin serum levels and history of alcohol withdrawal seizures
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    J Psychiatr Res 41:702-6. 2007
  7. ncbi request reprint Prolactin serum levels and alcohol craving - an analysis using Lesch's typology
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    Neuropsychobiology 53:133-6. 2006
  8. ncbi request reprint Nicotine dependence is associated with compulsive alcohol craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Addiction 101:892-7. 2006
  9. ncbi request reprint Biological markers to predict previous alcohol withdrawal seizures: a risk assessment
    T Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    J Neural Transm 114:151-4. 2007
  10. ncbi request reprint [Neurobiological mechanisms and pharmacological treatment options for alcohol craving]
    T Hillemacher
    Psychiatrische und Psychotherapeutische Klinik, Universitatsklinikum Erlangen, Germany
    Fortschr Neurol Psychiatr 75:26-32. 2007

Detail Information

Publications57

  1. ncbi request reprint Neurobiology and treatment in alcoholism--recent findings regarding Lesch's typology of alcohol dependence
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 43:341-6. 2008
    ..This applies in particular for genetic and neuroendocrinological factors, differences in the regulation of NMDA receptor-mediated glutamatergic neurotransmission, and in response to acamprosate and naltrexone treatment...
  2. ncbi request reprint Alteration of prolactin serum levels during alcohol withdrawal correlates with craving in female patients
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Addict Biol 10:337-43. 2005
    ....
  3. ncbi request reprint Recurrent detoxifications are associated with craving in patients classified as type 1 according to Lesch's typology
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 41:66-9. 2006
    ..The aim of this investigation was to study the influence of preceding detoxifications on craving in patients with alcoholism classified according to Lesch's typology...
  4. ncbi request reprint Influence of beer, wine and spirits consumption on craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Addict Biol 10:181-6. 2005
    ..In addition, it is an important predictor for both obsessive and compulsive craving. Further studies are needed to clarify the pathophysiological basis of this finding...
  5. ncbi request reprint Plasma homocysteine concentrations do not influence craving in alcohol withdrawal
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol 34:211-5. 2004
    ..Therefore, further research about alcohol craving should focus on neurobiologic factors other than homocysteine...
  6. ncbi request reprint Elevated prolactin serum levels and history of alcohol withdrawal seizures
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    J Psychiatr Res 41:702-6. 2007
    ..Prolactin has been discussed to be useful for differential diagnosis in epilepsia. Aim of the present study was to investigate the association between prolactin serum levels and previous alcohol withdrawal seizures...
  7. ncbi request reprint Prolactin serum levels and alcohol craving - an analysis using Lesch's typology
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    Neuropsychobiology 53:133-6. 2006
    ..Prolactin secretion is closely connected to dopaminergic transmission that is known to play a crucial role in mediating reinforcement and craving in alcoholism...
  8. ncbi request reprint Nicotine dependence is associated with compulsive alcohol craving
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Addiction 101:892-7. 2006
    ..To investigate a possible association of nicotine dependence and alcohol craving...
  9. ncbi request reprint Biological markers to predict previous alcohol withdrawal seizures: a risk assessment
    T Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    J Neural Transm 114:151-4. 2007
    ..001, OR = 9.23, 95%CI = 2.36-36.05). A combination of both, homocysteine and prolactin, may help to assess the individual risk of alcohol withdrawal seizures in clinical practice...
  10. ncbi request reprint [Neurobiological mechanisms and pharmacological treatment options for alcohol craving]
    T Hillemacher
    Psychiatrische und Psychotherapeutische Klinik, Universitatsklinikum Erlangen, Germany
    Fortschr Neurol Psychiatr 75:26-32. 2007
    ..Besides, there are several promising candidate substances. Current investigations focus on a differentiated pharmacotherapy of alcohol dependence, including psychological and genetic factors...
  11. ncbi request reprint Volume intake and craving in alcohol withdrawal
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 41:61-5. 2006
    ..The present study was undertaken to evaluate whether the daily volume intake of alcoholic beverages is associated with craving in patients undergoing alcohol withdrawal...
  12. ncbi request reprint Short-term cognition deficits during early alcohol withdrawal are associated with elevated plasma homocysteine levels in patients with alcoholism
    J Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    J Neural Transm 113:357-63. 2006
    ..68, 95% CI=0.57-0.79, p=0.004). The present results show first evidence of an association between elevated plasma homocysteine levels in alcoholics and cognition deficits in patients undergoing alcohol withdrawal...
  13. ncbi request reprint Herp mRNA expression in patients classified according to Lesch's typology
    T Biermann
    Department of Psychiatry and Psychotherapy, University Hospital of Erlangen, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol 43:91-5. 2009
    ..e., withdrawal seizures). These findings may be useful in the understanding and treatment considerations of different subtypes of alcohol dependence...
  14. ncbi request reprint The modulating effect of the androgen receptor on craving in alcohol withdrawal of men is partially mediated by leptin
    B Lenz
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Pharmacogenomics J 10:226-31. 2010
    ..Nevertheless future studies are needed to further explore the functionality of the androgen receptor gene in terms of craving...
  15. ncbi request reprint Cognitive impairment and its association with homocysteine plasma levels in females with eating disorders - findings from the HEaD-study
    H Frieling
    Department of Psychiatry and Psychotherapy, University Erlangen Nuremberg, Bad Oeynhausen, Germany
    J Neural Transm 112:1591-8. 2005
    ..566, OR=24.75, CI 2.89 - 212.23, P=0.003). These results indicate that under the special circumstances of eating disorders elevated homocysteine levels improve memory signaling possibly by facilitating long-term potentiation...
  16. doi request reprint Treatment with clomethiazole is associated with lower rates of premature discharge during alcohol withdrawal
    T Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Erlangen, Germany
    Pharmacopsychiatry 41:134-7. 2008
    ..The aim of the present study was to assess the risk of different possible influencing factors...
  17. ncbi request reprint Leptin is associated with craving in females with alcoholism
    T Kraus
    Department of Psychiatry and Psychotherapy, University Hospital, Erlangen, Germany
    Addict Biol 9:213-9. 2004
    ..Hence, gender differences have to be taken into account when searching for neurobiological models of alcohol craving...
  18. ncbi request reprint Apolipoprotein E polymorphism, homocysteine serum levels and hippocampal volume in patients with alcoholism: an investigation of a gene-environment interaction
    J Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Erlangen, Germany
    Pharmacogenomics J 8:117-21. 2008
    ..We suggest that the disadvantageous effects of apolipoprotein E4 on alcohol-related brain volume loss are based on certain gene-environment interactions...
  19. doi request reprint [Pharmacological treatment options for prevention of alcohol relapse]
    A Heberlein
    Psychiatrische und Psychotherapeutische Klinik, Universitatsklinikum Erlangen, Schwabachanlage 6, Erlangen
    Fortschr Neurol Psychiatr 76:421-8. 2008
    ..Therefore new therapy options are needed in order to treat alcohol dependent persons. Substances that seem to have efficacy in preclinical or preliminary clinical studies are baclofen, topiramate, odansetron, rimonabant and memantine...
  20. ncbi request reprint [New options in the treatment of depression]
    H Frieling
    Psychiatrische und Psychotherapeutische Klinik, Universitatsklinikum Erlangen
    Fortschr Neurol Psychiatr 75:641-52. 2007
    ..Glutamate modulating agents such as ketamine or riluzole are another promising approach in the treatment of depression. Some advances have also been achieved in the field of HPA-axis modulation...
  21. ncbi request reprint [Binge drinking in adolescents and young adults]
    D Karagülle
    Psychiatrische und Psychotherapeutische Klinik, Universitatsklinikum Erlangen, Germany
    Fortschr Neurol Psychiatr 78:196-202. 2010
    ..e. North American college students, adolescents in Australia etc.). More and intensive research in Germany and other European countries is urgently needed, as results from other cultural backgrounds are not necessarily transferable...
  22. doi request reprint [Benzodiazepine dependence: causalities and treatment options]
    A Heberlein
    Psychiatrische und Psychotherapeutische Klinik, Universitatsklinikum Erlangen, Erlangen, Germany
    Fortschr Neurol Psychiatr 77:7-15. 2009
    ..Anticonvulsants and antidepressants seem to reduce the intensity of benzodiazepine withdrawal and to enhance long term prognosis of dependence...
  23. ncbi request reprint Depressive symptoms may explain elevated plasma levels of homocysteine in females with eating disorders
    Helge Frieling
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlagen, Germany
    J Psychiatr Res 42:83-6. 2008
    ..8; df = 42; P = 0.008). Presence of depressive symptoms may explain elevated homocysteine levels previously reported in patients with eating disorders or vice versa. Longitudinal studies are needed to unravel this hen or egg problem...
  24. ncbi request reprint Alcoholism and homicide with respect to the classification systems of Lesch and Cloninger
    Udo Reulbach
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg Germany Schwabachanlage 6, 91054 Erlangen, Germany
    Alcohol Alcohol 42:103-7. 2007
    ..A psychopathological subtyping of alcohol dependence in offenders who committed homicide has mainly been related to impulsive and dissocial personalities up to now...
  25. ncbi request reprint Combinations of carbohydrate-deficient transferrin, mean corpuscular erythrocyte volume, gamma-glutamyltransferase, homocysteine and folate increase the significance of biological markers in alcohol dependent patients
    Daniela Rinck
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Germany
    Drug Alcohol Depend 89:60-5. 2007
    ..This study focuses on the combination of established laboratory parameters with new meaningful biomarkers to advance the significance regarding alcohol dependence...
  26. ncbi request reprint Association of the long allele of the 5-HTTLPR polymorphism with compulsive craving in alcohol dependence
    Stefan Bleich
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 42:509-12. 2007
    ..Various studies have reported a role of the serotonin transporter-linked polymorphic region (5-HTTLPR) in alcoholism...
  27. ncbi request reprint Hippocampal volume loss in patients with alcoholism is influenced by the consumed type of alcoholic beverage
    Julia Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 43:296-9. 2008
    ..Aim of the present study was to investigate different types of alcoholic beverages with regard to hippocampal volume loss in patients suffering from alcoholism...
  28. ncbi request reprint Role of appetite-regulating peptides in alcohol craving: an analysis in respect to subtypes and different consumption patterns in alcoholism
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Erlangen, Germany
    Alcohol Clin Exp Res 31:950-4. 2007
    ..Aim of this analysis was to search for differences regarding an association between these peptides and alcohol craving with respect to different subtypes and beverage consumption patterns in patients with alcohol dependence...
  29. ncbi request reprint NGF plasma levels increase due to alcohol intoxication and decrease during withdrawal
    Annemarie Heberlein
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Psychoneuroendocrinology 33:999-1003. 2008
    ..These results suggest that NGF plasma levels increase as part of a regulation mechanism that counteracts alcohol intoxication...
  30. ncbi request reprint Alcoholism, craving, and hormones: the role of leptin, ghrelin, prolactin, and the pro-opiomelanocortin system in modulating ethanol intake
    Friedrich Martin Wurst
    Christian Doppler Clinic, Department of Psychiatry and Psychotherapy II Addiction Medicine, Paracelsus Medical University, Salzburg, Austria
    Alcohol Clin Exp Res 31:1963-7. 2007
    ..The goal of this mini-review is to discuss the results of some recent investigations of the potential interactions of these systems with acute and chronic alcohol responses...
  31. ncbi request reprint Neuroendocrine pathways in benzodiazepine dependence: new targets for research and therapy
    Annemarie Heberlein
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Germany
    Hum Psychopharmacol 23:171-81. 2008
    ..Depending on the available results possible implications of NPY and CCK on benzodiazepine addiction and withdrawal symptoms are reviewed, thereby providing topics for further research...
  32. ncbi request reprint Obsessive-compulsive alcohol craving is not associated with Apolipoprotein E genotype
    Thomas Hillemacher
    Psychiatr Genet 16:231-2. 2006
    ..Statistical analysis revealed no significant association between Apolipoprotein E polymorphism and obsessive-compulsive alcohol craving (analysis of variance: F=1.11, P=0.358)...
  33. ncbi request reprint Evidence of an association of leptin serum levels and craving in alcohol dependence
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Psychoneuroendocrinology 32:87-90. 2007
    ..160, t=5.793, p<0.001) with a power of 1.00. In contrast to previous results describing an association only in female patients, this power-based analysis shows that leptin is associated with alcohol craving in both genders...
  34. ncbi request reprint Treating dopamimetic psychosis in Parkinson's disease: structured review and meta-analysis
    Helge Frieling
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Eur Neuropsychopharmacol 17:165-71. 2007
    ..Based on randomized trial-derived evidence which is currently available, only clozapine can be fully recommended for the treatment of DIP in PD. Olanzapine should not be used in this indication...
  35. ncbi request reprint Homocysteine levels in patients classified according to Lesch's typology
    Stefan Bleich
    Friedrich Alexander, University of Erlangen Nuremberg, Department of Psychiatry and Psychotherapy, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol Alcohol 39:493-8. 2004
    ..This study was undertaken to investigate total plasma homocysteine levels in actively drinking patients with alcoholism who were classified according to Lesch's typology...
  36. ncbi request reprint Elevated alpha synuclein mRNA levels are associated with craving in patients with alcoholism
    Dominikus Bönsch
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, 91054 Erlangen, Germany
    Biol Psychiatry 56:984-6. 2004
    ..Alpha synuclein has been found elevated in dopamine neurons of cocaine abusers and in rats whose alcohol preference is inbred...
  37. ncbi request reprint Evidence of increased homocysteine levels in alcoholism: the Franconian alcoholism research studies (FARS)
    Stefan Bleich
    Friedrich Alexander University of Erlangen Nuremberg, Department of Psychiatry and Psychotherapy, Schwabachanlage 6, 91054 Erlangen, Germany
    Alcohol Clin Exp Res 29:334-6. 2005
    ..Therefore, this power analysis-based study was undertaken to determine whether plasma homocysteine levels are evidently altered in actively drinking alcoholic patients and patients with early abstinence...
  38. ncbi request reprint Alpha-synuclein protein levels are increased in alcoholic patients and are linked to craving
    Dominikus Bönsch
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Alcohol Clin Exp Res 29:763-5. 2005
    ..The aim of the current study was to investigate whether protein levels of alpha synuclein in alcoholics are changed and possibly influence alcohol craving...
  39. ncbi request reprint Alcoholism-associated hyperhomocysteinemia and previous withdrawal seizures
    Kristina Bayerlein
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Biol Psychiatry 57:1590-3. 2005
    ....
  40. ncbi request reprint Subjective experience and coping in ALS
    Martin Hecht
    Department of Neurology, Centre of Neuromuscular Diseases, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Amyotroph Lateral Scler Other Motor Neuron Disord 3:225-31. 2002
    ..Amyotrophic lateral sclerosis is a rapidly progressive and fatal disease which has no known cure and limited symptomatic treatment. While coping strategies in more common diseases are widely assessed, coping is poorly understood in ALS...
  41. ncbi request reprint Ghrelin levels are increased in alcoholism
    Thomas Kraus
    Department of Psychiatry and Psychotherapy, University Hospital, Erlangen, Germany
    Alcohol Clin Exp Res 29:2154-7. 2005
    ..Therefore, the aim of the present pilot study was to determine whether the gut-derived peptide ghrelin which increases hunger and food intake is altered and associated with alcohol craving in alcoholic patients..
  42. ncbi request reprint Burden of care in amyotrophic lateral sclerosis
    Martin J Hecht
    Department of Neurology, Centre of Neuromuscular Diseases, University of Erlangen Nuremberg, Erlangen, Germany
    Palliat Med 17:327-33. 2003
    ..Amyotrophic lateral sclerosis (ALS) is a fatal disease with unique demands on patients and carers...
  43. ncbi request reprint Association of catecholamine-O-methyltransferase and 5-HTTLPR genotype with eating disorder-related behavior and attitudes in females with eating disorders
    Helge Frieling
    Department of Psychiatry and Psychotherapy, University Erlangen Nuremberg, Erlangen, Germany
    Psychiatr Genet 16:205-8. 2006
    ..The aim of the present study was to evaluate, whether behavioral and attitudinal traits of the disorders can serve as phenotypes with a possible association with two common functional polymorphisms of the monoaminergic pathways...
  44. ncbi request reprint Apolipoprotein E gene polymorphism and previous alcohol withdrawal seizures
    Julia Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Psychiatr Res 41:871-5. 2007
    ..Our findings suggest an association between the apolipoprotein E3 gene variant and an elevated risk of alcohol withdrawal seizures. These preliminary results must be validated in further studies...
  45. ncbi request reprint Different allele-distribution of mthfr 677 C -> T and mthfr -393 C -> a in patients classified according to subtypes of Lesch's typology
    Dominikus Bönsch
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6 91054 Erlangen, Germany
    Alcohol Alcohol 41:364-7. 2006
    ....
  46. ncbi request reprint An assessment of the potential value of elevated homocysteine in predicting alcohol-withdrawal seizures
    Stefan Bleich
    Department of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Epilepsia 47:934-8. 2006
    ..The aim of the present study was to calculate the best predictive cutoff value of plasma homocysteine levels in actively drinking alcoholics (n = 88) with first-onset alcohol-withdrawal seizures...
  47. ncbi request reprint Apolipoprotein E4 genotype is not associated with short-term cognition deficits during alcohol withdrawal
    Julia Wilhelm
    Department of Psychiatry and Psychotherapy, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Alcohol 37:151-6. 2005
    ....
  48. ncbi request reprint Genetic predisposition to neuroleptic malignant syndrome in siblings
    Marc Ziegenbein
    Ann Pharmacother 40:574-5. 2006
  49. ncbi request reprint Psychotic episode possibly induced by light therapy in a nondemented patient
    Thomas Hillemacher
    J Clin Psychiatry 67:997-8. 2006
  50. ncbi request reprint Depression and bulbar involvement in amyotrophic lateral sclerosis
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, Centre of Neuromuscular Diseases, University of Erlangen Nuremberg, Germany
    Amyotroph Lateral Scler Other Motor Neuron Disord 5:245-9. 2004
    ..Patients with amyotrophic lateral sclerosis (ALS) often develop depressive symptoms. Little is known of the factors that predict or influence depression in ALS patients...
  51. ncbi request reprint Recurrent hyponatremia under desmopressin overdosing: is abuse a possible explication?
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, D 91054 Erlangen, Germany
    Am J Emerg Med 25:239-40. 2007
  52. ncbi request reprint Limited use of CK-MB as a screening parameter for acute coronary syndrome in patients with alcohol dependency
    Julia Wilhelm
    J Stud Alcohol 66:577-8. 2005
  53. doi request reprint Global DNA methylation is influenced by smoking behaviour
    Thomas Hillemacher
    Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Erlangen, Germany
    Eur Neuropsychopharmacol 18:295-8. 2008
    ..68, p=0.02) and completely vanished if the offspring smoked or had ever smoked. These findings suggest an association between smoking behaviour and global DNA methylation, which may be of importance for a wide range of diseases...
  54. ncbi request reprint Elevated prenatal homocysteine levels and the risk of schizophrenia
    Stefan Bleich
    Arch Gen Psychiatry 64:980-1. 2007
  55. ncbi request reprint Should aspirin be discontinued for diagnostic lumbar puncture?
    Thomas Hillemacher
    J Am Geriatr Soc 54:181-2. 2006
  56. ncbi request reprint Homocysteine and epigenetic DNA methylation: a biological model for depression?
    Thomas Hillemacher
    Am J Psychiatry 164:1610. 2007
  57. ncbi request reprint Extensive craving in high dose zolpidem dependency
    Jana Svitek
    Prog Neuropsychopharmacol Biol Psychiatry 32:591-2. 2008