Martin G Friedrich

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint Long-term intravesical adjuvant chemotherapy further reduces recurrence rate compared with short-term intravesical chemotherapy and short-term therapy with Bacillus Calmette-Guérin (BCG) in patients with non-muscle-invasive bladder carcinoma
    Martin G Friedrich
    Department of Urology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 52:1123-29. 2007
  2. ncbi request reprint Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma
    Martin G Friedrich
    Department of Urology, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089 9176, USA
    Eur J Cancer 41:2769-78. 2005
  3. ncbi request reprint Expression of Maspin in non-muscle invasive bladder carcinoma: correlation with tumor angiogenesis and prognosis
    Martin G Friedrich
    Department of Urology, University of Hamburg, University Hospital Hamburg Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Eur Urol 45:737-43. 2004
  4. ncbi request reprint Are false-positive urine markers for the detection of bladder carcinoma really wrong or do they predict tumor recurrence?
    Martin G Friedrich
    University Hospital Eppendorf, Department of Urology, University of Hamburg, Martinistrasse 52, D 20246, Hamburg, Germany
    Eur Urol 43:146-50; discussion 150-1. 2003
  5. ncbi request reprint Variability in the performance of nuclear matrix protein 22 for the detection of bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:919-26; discussion 926. 2006
  6. ncbi request reprint Contemporary prostate cancer prevalence among T1c biopsy-referred men with a prostate-specific antigen level < or = 4.0 ng per milliliter
    Sascha A Ahyai
    Department of Urology, University of Hamburg, Hamburg, Germany
    Eur Urol 53:750-7. 2008
  7. ncbi request reprint Circulating tumour-associated plasma DNA represents an independent and informative predictor of prostate cancer
    Felix K H Chun
    Department of Urology, University Hospital Hamburg Epppendorf, Hamburg, Germany
    BJU Int 98:544-8. 2006
  8. ncbi request reprint Significant upgrading affects a third of men diagnosed with prostate cancer: predictive nomogram and internal validation
    Felix K H Chun
    Department of Urology, University of Hamburg, Hamburg, Germany
    BJU Int 98:329-34. 2006
  9. ncbi request reprint Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients
    Martin G Friedrich
    Departments of Urology, Clinical Pathology, and Preventive Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089 9176, USA
    Clin Cancer Res 10:7457-65. 2004
  10. ncbi request reprint Detection of human telomerase RNA in the tumour-surrounding mucosa of bladder carcinomas as a marker for premalignant transformation
    Sven Leuenroth
    Institute of Pathology, University Hospital Hamburg Eppendorf, University of Hamburg, Germany
    BJU Int 96:553-7. 2005

Detail Information

Publications26

  1. ncbi request reprint Long-term intravesical adjuvant chemotherapy further reduces recurrence rate compared with short-term intravesical chemotherapy and short-term therapy with Bacillus Calmette-Guérin (BCG) in patients with non-muscle-invasive bladder carcinoma
    Martin G Friedrich
    Department of Urology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 52:1123-29. 2007
    ....
  2. ncbi request reprint Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma
    Martin G Friedrich
    Department of Urology, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089 9176, USA
    Eur J Cancer 41:2769-78. 2005
    ..We identified one gene (TIMP-3) where methylation was associated with a more favourable outcome. Our data strongly support the usefulness of gene methylation as a prognostic marker in patients with non-muscle invasive bladder cancer...
  3. ncbi request reprint Expression of Maspin in non-muscle invasive bladder carcinoma: correlation with tumor angiogenesis and prognosis
    Martin G Friedrich
    Department of Urology, University of Hamburg, University Hospital Hamburg Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Eur Urol 45:737-43. 2004
    ..We studied expression patterns of Maspin in pTa/pT1 urothelial carcinoma of the bladder and compared them with microvessel density (MVD) for two vascular markers (CD34 and CD105) and correlated the findings with clinical outcome...
  4. ncbi request reprint Are false-positive urine markers for the detection of bladder carcinoma really wrong or do they predict tumor recurrence?
    Martin G Friedrich
    University Hospital Eppendorf, Department of Urology, University of Hamburg, Martinistrasse 52, D 20246, Hamburg, Germany
    Eur Urol 43:146-50; discussion 150-1. 2003
    ..We studied whether patients with false-positive results of various urine test had a higher recurrence rate than patients with true-negative results...
  5. ncbi request reprint Variability in the performance of nuclear matrix protein 22 for the detection of bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:919-26; discussion 926. 2006
    ..We assessed variability in the diagnostic performance of NMP22 for detecting recurrence and progression in patients with Ta, T1, and/or CIS transitional cell carcinoma of the bladder in a large international cohort...
  6. ncbi request reprint Contemporary prostate cancer prevalence among T1c biopsy-referred men with a prostate-specific antigen level < or = 4.0 ng per milliliter
    Sascha A Ahyai
    Department of Urology, University of Hamburg, Hamburg, Germany
    Eur Urol 53:750-7. 2008
    ..To investigate the prostate cancer (PCa) prevalence and risk factors of men with prostate-specific antigen (PSA) level< or =4.0 ng/ml and an unsuspicious digital rectal examination (DRE) in a large biopsy referral cohort...
  7. ncbi request reprint Circulating tumour-associated plasma DNA represents an independent and informative predictor of prostate cancer
    Felix K H Chun
    Department of Urology, University Hospital Hamburg Epppendorf, Hamburg, Germany
    BJU Int 98:544-8. 2006
    ..To investigate whether preoperative plasma levels of free DNA can discriminate between men with localized prostate cancer and benign prostatic hyperplasia (BPH)...
  8. ncbi request reprint Significant upgrading affects a third of men diagnosed with prostate cancer: predictive nomogram and internal validation
    Felix K H Chun
    Department of Urology, University of Hamburg, Hamburg, Germany
    BJU Int 98:329-34. 2006
    ....
  9. ncbi request reprint Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients
    Martin G Friedrich
    Departments of Urology, Clinical Pathology, and Preventive Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089 9176, USA
    Clin Cancer Res 10:7457-65. 2004
    ....
  10. ncbi request reprint Detection of human telomerase RNA in the tumour-surrounding mucosa of bladder carcinomas as a marker for premalignant transformation
    Sven Leuenroth
    Institute of Pathology, University Hospital Hamburg Eppendorf, University of Hamburg, Germany
    BJU Int 96:553-7. 2005
    ..To investigate tumour tissue and non-malignant tumour-surrounding bladder mucosa (NTSBM) for expression of human telomerase RNA (hTR) as a possible marker for premalignant transformation of urothelial cells...
  11. ncbi request reprint Comparison of the ImmunoCyt test and urinary cytology with other urine tests in the detection and surveillance of bladder cancer
    Marieta I Toma
    Department of Urology, University of Hamburg, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    World J Urol 22:145-9. 2004
    ..The combination of ImmunoCyt with conventional cytology offers a superior sensitivity to other commercial tests. The ImmunoCyt test provides a useful supplement to urinary cytology in the diagnosis of bladder cancer...
  12. ncbi request reprint Immunocyt and the HA-HAase urine tests for the detection of bladder cancer: a side-by-side comparison
    Stefan Hautmann
    Department of Urology, University Hospital, University of Kiel, Arnold Heller Str 7, 24105 Kiel, Germany
    Eur Urol 46:466-71. 2004
    ..With the HA-HAase urine test the level of hyaluronic acid (HA) and its degrading enzyme hyaluronidase (HAase) are measured in an ELISA-like test...
  13. ncbi request reprint Nomograms including nuclear matrix protein 22 for prediction of disease recurrence and progression in patients with Ta, T1 or CIS transitional cell carcinoma of the bladder
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 173:1518-25. 2005
    ..We developed and validated nomograms that accurately predict disease recurrence and progression in patients with Ta, T1, or CIS transitional cell carcinoma (TCC) of the bladder using a large international cohort...
  14. ncbi request reprint Clinical use of urinary markers for the detection and prognosis of bladder carcinoma: a comparison of immunocytology with monoclonal antibodies against Lewis X and 486p3/12 with the BTA STAT and NMP22 tests
    Martin G Friedrich
    Department of Urology, University Hospital, University of Hamburg, Hamburg, Germany
    J Urol 168:470-4. 2002
    ..We compared the NMP22 (Matritech, Cambridge, Massachusetts) and BTA Stat (Bard Diagnostics, Redmond, Washington) tests with immunocytology using mAbs 486p3/12 and BG7 against Lewis X antigen...
  15. doi request reprint Microsatellite analysis of allelic imbalance in tumour and blood from patients with prostate cancer
    Heidi Schwarzenbach
    Institute of Tumour Biology, University Medical Centre, Hamburg Eppendorf, Germany
    BJU Int 102:253-8. 2008
    ..To investigate whether a high frequency of allelic imbalance (AI) is associated with clinicopathological variables of patients with prostate cancer...
  16. ncbi request reprint Methylation of the TPEF- and PAX6-promoters is increased in early bladder cancer and in normal mucosa adjacent to pTa tumours
    Olaf J C Hellwinkel
    Martini Prostate Cancer Center, Department of Urology, University Hospital Eppendorf, Hamburg, Germany
    BJU Int 101:753-7. 2008
    ..To evaluate CpG island methylation patterns of cancer-associated genes for their applicability as molecular biomarkers for the detection of superficial bladder cancer and for the discrimination of invasive from noninvasive tumours...
  17. ncbi request reprint Extracorporeal shockwave lithotripsy compared with ureteroscopy for the removal of small distal ureteral stones
    Stefan Hautmann
    Department of Urology, University Hospital Hamburg, Eppendorf, Hamburg, Germany
    Urol Int 73:238-43. 2004
    ..The objective was to analyze the stone-free rate after treatment of distal ureteral stones with in situ SWL or URS...
  18. ncbi request reprint A side by side comparison of cytology and biomarkers for bladder cancer detection
    Grethchen L Schroeder
    Department of Urology, University of Miami School of Medicine, Miami, FL 33101, USA
    J Urol 172:1123-6. 2004
    ....
  19. doi request reprint Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective study
    Michael Rink
    Department of Urology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 61:810-7. 2012
    ..Preliminary research has suggested the potential prognostic value of circulating tumor cells (CTC) in patients with advanced nonmetastatic urothelial carcinoma of the bladder (UCB)...
  20. ncbi request reprint Prediction of postoperative sexual function after nerve sparing radical retropubic prostatectomy
    Uwe H G Michl
    Department of Urology, University of Hamburg, University Hospital Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    J Urol 176:227-31. 2006
    ....
  21. ncbi request reprint Surgical volume is related to the rate of positive surgical margins at radical prostatectomy in European patients
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    BJU Int 98:1204-9. 2006
    ..To assess the association between surgical volume (SV) and the rate of positive surgical margins (PSM) after radical prostatectomy (RP) in a large single-institution European cohort of patients...
  22. ncbi request reprint Detection of tumor-specific DNA in blood and bone marrow plasma from patients with prostate cancer
    Heidi Schwarzenbach
    Institute of Tumor Biology, University Medical Center Hamburg Eppendorf, Germany
    Int J Cancer 120:1465-71. 2007
    ..These data demonstrate, for the first time, the presence of free tumor-specific DNA in blood and BM of PCa patients and suggest a possible relationship to BM micrometastasis...
  23. ncbi request reprint Institutional variability in the accuracy of urinary cytology for predicting recurrence of transitional cell carcinoma of the bladder
    Pierre I Karakiewicz
    Department of Urology, University of Montreal, Montreal, Quebec, Canada
    BJU Int 97:997-1001. 2006
    ....
  24. doi request reprint Urinary cytology and nuclear matrix protein 22 in the detection of bladder cancer recurrence other than transitional cell carcinoma
    Georg C Hutterer
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    BJU Int 101:561-5. 2008
    ..To assess the value of nuclear matrix protein-22 (NMP22), compared with urinary cytology, in predicting the recurrence of bladder cancer that is not transitional cell carcinoma (non-TCC)...
  25. ncbi request reprint [Prostate carcinoma: higher COX-2 contents in advanced tumors]
    Johannes Weiss
    Aktuelle Urol 35:359-61. 2004
  26. ncbi request reprint [Superficial bladder carcinoma -- trend of less aggressive therapies]
    Martin G Friedrich
    Aktuelle Urol 37:254-6. 2006