Martin G Friedrich
Affiliation: University of Hamburg
- Long-term intravesical adjuvant chemotherapy further reduces recurrence rate compared with short-term intravesical chemotherapy and short-term therapy with Bacillus Calmette-Guérin (BCG) in patients with non-muscle-invasive bladder carcinomaMartin G Friedrich
Department of Urology, University Hospital Hamburg Eppendorf, Hamburg, Germany
Eur Urol 52:1123-29. 2007....
- Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinomaMartin G Friedrich
Department of Urology, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089 9176, USA
Eur J Cancer 41:2769-78. 2005..We identified one gene (TIMP-3) where methylation was associated with a more favourable outcome. Our data strongly support the usefulness of gene methylation as a prognostic marker in patients with non-muscle invasive bladder cancer...
- Expression of Maspin in non-muscle invasive bladder carcinoma: correlation with tumor angiogenesis and prognosisMartin G Friedrich
Department of Urology, University of Hamburg, University Hospital Hamburg Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
Eur Urol 45:737-43. 2004..We studied expression patterns of Maspin in pTa/pT1 urothelial carcinoma of the bladder and compared them with microvessel density (MVD) for two vascular markers (CD34 and CD105) and correlated the findings with clinical outcome...
- Are false-positive urine markers for the detection of bladder carcinoma really wrong or do they predict tumor recurrence?Martin G Friedrich
University Hospital Eppendorf, Department of Urology, University of Hamburg, Martinistrasse 52, D 20246, Hamburg, Germany
Eur Urol 43:146-50; discussion 150-1. 2003..We studied whether patients with false-positive results of various urine test had a higher recurrence rate than patients with true-negative results...
- Variability in the performance of nuclear matrix protein 22 for the detection of bladder cancerShahrokh F Shariat
Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
J Urol 176:919-26; discussion 926. 2006..We assessed variability in the diagnostic performance of NMP22 for detecting recurrence and progression in patients with Ta, T1, and/or CIS transitional cell carcinoma of the bladder in a large international cohort...
- Contemporary prostate cancer prevalence among T1c biopsy-referred men with a prostate-specific antigen level < or = 4.0 ng per milliliterSascha A Ahyai
Department of Urology, University of Hamburg, Hamburg, Germany
Eur Urol 53:750-7. 2008..To investigate the prostate cancer (PCa) prevalence and risk factors of men with prostate-specific antigen (PSA) level< or =4.0 ng/ml and an unsuspicious digital rectal examination (DRE) in a large biopsy referral cohort...
- Circulating tumour-associated plasma DNA represents an independent and informative predictor of prostate cancerFelix K H Chun
Department of Urology, University Hospital Hamburg Epppendorf, Hamburg, Germany
BJU Int 98:544-8. 2006..To investigate whether preoperative plasma levels of free DNA can discriminate between men with localized prostate cancer and benign prostatic hyperplasia (BPH)...
- Significant upgrading affects a third of men diagnosed with prostate cancer: predictive nomogram and internal validationFelix K H Chun
Department of Urology, University of Hamburg, Hamburg, Germany
BJU Int 98:329-34. 2006....
- Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patientsMartin G Friedrich
Departments of Urology, Clinical Pathology, and Preventive Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089 9176, USA
Clin Cancer Res 10:7457-65. 2004....
- Detection of human telomerase RNA in the tumour-surrounding mucosa of bladder carcinomas as a marker for premalignant transformationSven Leuenroth
Institute of Pathology, University Hospital Hamburg Eppendorf, University of Hamburg, Germany
BJU Int 96:553-7. 2005..To investigate tumour tissue and non-malignant tumour-surrounding bladder mucosa (NTSBM) for expression of human telomerase RNA (hTR) as a possible marker for premalignant transformation of urothelial cells...
- Comparison of the ImmunoCyt test and urinary cytology with other urine tests in the detection and surveillance of bladder cancerMarieta I Toma
Department of Urology, University of Hamburg, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
World J Urol 22:145-9. 2004..The combination of ImmunoCyt with conventional cytology offers a superior sensitivity to other commercial tests. The ImmunoCyt test provides a useful supplement to urinary cytology in the diagnosis of bladder cancer...
- Immunocyt and the HA-HAase urine tests for the detection of bladder cancer: a side-by-side comparisonStefan Hautmann
Department of Urology, University Hospital, University of Kiel, Arnold Heller Str 7, 24105 Kiel, Germany
Eur Urol 46:466-71. 2004..With the HA-HAase urine test the level of hyaluronic acid (HA) and its degrading enzyme hyaluronidase (HAase) are measured in an ELISA-like test...
- Nomograms including nuclear matrix protein 22 for prediction of disease recurrence and progression in patients with Ta, T1 or CIS transitional cell carcinoma of the bladderShahrokh F Shariat
Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
J Urol 173:1518-25. 2005..We developed and validated nomograms that accurately predict disease recurrence and progression in patients with Ta, T1, or CIS transitional cell carcinoma (TCC) of the bladder using a large international cohort...
- Clinical use of urinary markers for the detection and prognosis of bladder carcinoma: a comparison of immunocytology with monoclonal antibodies against Lewis X and 486p3/12 with the BTA STAT and NMP22 testsMartin G Friedrich
Department of Urology, University Hospital, University of Hamburg, Hamburg, Germany
J Urol 168:470-4. 2002..We compared the NMP22 (Matritech, Cambridge, Massachusetts) and BTA Stat (Bard Diagnostics, Redmond, Washington) tests with immunocytology using mAbs 486p3/12 and BG7 against Lewis X antigen...
- Microsatellite analysis of allelic imbalance in tumour and blood from patients with prostate cancerHeidi Schwarzenbach
Institute of Tumour Biology, University Medical Centre, Hamburg Eppendorf, Germany
BJU Int 102:253-8. 2008..To investigate whether a high frequency of allelic imbalance (AI) is associated with clinicopathological variables of patients with prostate cancer...
- Methylation of the TPEF- and PAX6-promoters is increased in early bladder cancer and in normal mucosa adjacent to pTa tumoursOlaf J C Hellwinkel
Martini Prostate Cancer Center, Department of Urology, University Hospital Eppendorf, Hamburg, Germany
BJU Int 101:753-7. 2008..To evaluate CpG island methylation patterns of cancer-associated genes for their applicability as molecular biomarkers for the detection of superficial bladder cancer and for the discrimination of invasive from noninvasive tumours...
- Extracorporeal shockwave lithotripsy compared with ureteroscopy for the removal of small distal ureteral stonesStefan Hautmann
Department of Urology, University Hospital Hamburg, Eppendorf, Hamburg, Germany
Urol Int 73:238-43. 2004..The objective was to analyze the stone-free rate after treatment of distal ureteral stones with in situ SWL or URS...
- A side by side comparison of cytology and biomarkers for bladder cancer detectionGrethchen L Schroeder
Department of Urology, University of Miami School of Medicine, Miami, FL 33101, USA
J Urol 172:1123-6. 2004....
- Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective studyMichael Rink
Department of Urology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
Eur Urol 61:810-7. 2012..Preliminary research has suggested the potential prognostic value of circulating tumor cells (CTC) in patients with advanced nonmetastatic urothelial carcinoma of the bladder (UCB)...
- Prediction of postoperative sexual function after nerve sparing radical retropubic prostatectomyUwe H G Michl
Department of Urology, University of Hamburg, University Hospital Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
J Urol 176:227-31. 2006....
- Surgical volume is related to the rate of positive surgical margins at radical prostatectomy in European patientsFelix K H Chun
Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
BJU Int 98:1204-9. 2006..To assess the association between surgical volume (SV) and the rate of positive surgical margins (PSM) after radical prostatectomy (RP) in a large single-institution European cohort of patients...
- Detection of tumor-specific DNA in blood and bone marrow plasma from patients with prostate cancerHeidi Schwarzenbach
Institute of Tumor Biology, University Medical Center Hamburg Eppendorf, Germany
Int J Cancer 120:1465-71. 2007..These data demonstrate, for the first time, the presence of free tumor-specific DNA in blood and BM of PCa patients and suggest a possible relationship to BM micrometastasis...
- Institutional variability in the accuracy of urinary cytology for predicting recurrence of transitional cell carcinoma of the bladderPierre I Karakiewicz
Department of Urology, University of Montreal, Montreal, Quebec, Canada
BJU Int 97:997-1001. 2006....
- Urinary cytology and nuclear matrix protein 22 in the detection of bladder cancer recurrence other than transitional cell carcinomaGeorg C Hutterer
Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
BJU Int 101:561-5. 2008..To assess the value of nuclear matrix protein-22 (NMP22), compared with urinary cytology, in predicting the recurrence of bladder cancer that is not transitional cell carcinoma (non-TCC)...
- [Prostate carcinoma: higher COX-2 contents in advanced tumors]Johannes Weiss
Aktuelle Urol 35:359-61. 2004
- [Superficial bladder carcinoma -- trend of less aggressive therapies]Martin G Friedrich
Aktuelle Urol 37:254-6. 2006