U Frank

Summary

Affiliation: University of Freiburg
Country: Germany

Publications

  1. ncbi request reprint Comparative in vitro activity of piperacillin, piperacillin-sulbactam and piperacillin-tazobactam against nosocomial pathogens isolated from intensive care patients
    U Frank
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetter Strasse 55, D 79106 Freiburg i Br, Germany
    Clin Microbiol Infect 9:1128-32. 2003
  2. ncbi request reprint The organization of infection control in Germany
    U Frank
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Freiburg, Germany
    J Hosp Infect 49:9-13. 2001
  3. ncbi request reprint Influence of mistletoe ( Viscum album) extracts on phagocytosis/burst activity of human phagocytes
    U Frank
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetterstrasse 55, 79106, Freiburg, Germany
    Eur J Clin Microbiol Infect Dis 22:501-3. 2003
  4. ncbi request reprint The effect of azithromycin on intracellular Legionella pneumophila in the Mono Mac 6 cell line at serum concentrations attainable in vivo
    D Jonas
    National Reference Centre of Hygiene and Institute of Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Hugstetter Strasse 55, D 79106 Freiburg, Germany
    J Antimicrob Chemother 46:385-90. 2000
  5. ncbi request reprint In vitro susceptibility to everninomycin of gram-positive nosocomial pathogens isolated from intensive care units in Germany
    A Kropec
    Institute of Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Freiburg, Germany
    Chemotherapy 47:15-8. 2001
  6. ncbi request reprint Surveillance of nosocomial infections in adult recipients of allogeneic and autologous bone marrow and peripheral blood stem-cell transplantation
    M Dettenkofer
    Institute of Environmental Medicine and Hospital Epidemiology, University Hospital of Freiburg, Germany
    Bone Marrow Transplant 31:795-801. 2003
  7. doi request reprint Epidemiology meets econometrics: using time-series analysis to observe the impact of bed occupancy rates on the spread of multidrug-resistant bacteria
    K Kaier
    Department of Environmental Health Sciences, University Medical Center Freiburg, Freiburg, Germany
    J Hosp Infect 76:108-13. 2010
  8. ncbi request reprint Effects of caspofungin (MK-0991) and anidulafungin (LY303366) on phagocytosis, oxidative burst and killing of Candida albicans by human phagocytes
    U Frank
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetterstrasse 55, 79106, Freiburg, Germany
    Eur J Clin Microbiol Infect Dis 23:729-31. 2004
  9. ncbi request reprint Efficacy of moxifloxacin, trovafloxacin, clinafloxacin and levofloxacin against intracellular Legionella pneumophila
    D Jonas
    National Reference Centre of Hygiene and Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetter Strasse 55, D 79106 Freiburg, Germany
    J Antimicrob Chemother 47:147-52. 2001
  10. doi request reprint Antimicrobial resistance in Escherichia coli strains isolated from food, animals and humans in Germany
    E Meyer
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Breisacher Str 115 b, 79106, Freiburg, Germany
    Infection 36:59-61. 2008

Detail Information

Publications22

  1. ncbi request reprint Comparative in vitro activity of piperacillin, piperacillin-sulbactam and piperacillin-tazobactam against nosocomial pathogens isolated from intensive care patients
    U Frank
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetter Strasse 55, D 79106 Freiburg i Br, Germany
    Clin Microbiol Infect 9:1128-32. 2003
    ..Piperacillin-sulbactam exhibited better antimicrobial activity against Acinetobacter baumannii. Our findings might prove important for the appropriate choice of antibiotic therapy with beta-lactam-beta-lactamase inhibitor combinations...
  2. ncbi request reprint The organization of infection control in Germany
    U Frank
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Freiburg, Germany
    J Hosp Infect 49:9-13. 2001
    ..The authors outline the organization of infection control in Germany, focusing on official regulations, the training of infection control staff, and functions of the infection control committee and the availability of guidelines...
  3. ncbi request reprint Influence of mistletoe ( Viscum album) extracts on phagocytosis/burst activity of human phagocytes
    U Frank
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetterstrasse 55, 79106, Freiburg, Germany
    Eur J Clin Microbiol Infect Dis 22:501-3. 2003
    ..025 to 20 ng/ml showed only marginal influence on phagocyte activity. Contrary to the opinion of numerous practitioners of complementary medicine, the mistletoe preparations tested do not enhance phagocytic function...
  4. ncbi request reprint The effect of azithromycin on intracellular Legionella pneumophila in the Mono Mac 6 cell line at serum concentrations attainable in vivo
    D Jonas
    National Reference Centre of Hygiene and Institute of Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Hugstetter Strasse 55, D 79106 Freiburg, Germany
    J Antimicrob Chemother 46:385-90. 2000
    ..pneumophila. In particular, azithromycin killed ingested legionellae in vitro at concentrations below the peak serum concentrations and below the MIC...
  5. ncbi request reprint In vitro susceptibility to everninomycin of gram-positive nosocomial pathogens isolated from intensive care units in Germany
    A Kropec
    Institute of Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Freiburg, Germany
    Chemotherapy 47:15-8. 2001
    ..However, avilamycin, a related compound, has been used in Europe as a growth promoter in animal food for years and concern has been raised that cross-resistance in clinical isolates may arise...
  6. ncbi request reprint Surveillance of nosocomial infections in adult recipients of allogeneic and autologous bone marrow and peripheral blood stem-cell transplantation
    M Dettenkofer
    Institute of Environmental Medicine and Hospital Epidemiology, University Hospital of Freiburg, Germany
    Bone Marrow Transplant 31:795-801. 2003
    ..9 vs 1.8 pneumonias, 3.0 vs 2.9 gastroenteritis, and 1.6 vs 0.3 urinary tract infections. The greatest number of NI in BMT and PBSCT recipients is acquired during neutropenia, and multicentre surveillance programmes should focus on this...
  7. doi request reprint Epidemiology meets econometrics: using time-series analysis to observe the impact of bed occupancy rates on the spread of multidrug-resistant bacteria
    K Kaier
    Department of Environmental Health Sciences, University Medical Center Freiburg, Freiburg, Germany
    J Hosp Infect 76:108-13. 2010
    ..Overcrowding in general wards and long periods of ICU stay were identified as factors influencing the spread of multidrug-resistant bacteria in hospital settings...
  8. ncbi request reprint Effects of caspofungin (MK-0991) and anidulafungin (LY303366) on phagocytosis, oxidative burst and killing of Candida albicans by human phagocytes
    U Frank
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetterstrasse 55, 79106, Freiburg, Germany
    Eur J Clin Microbiol Infect Dis 23:729-31. 2004
    ..4% and 43.2%, respectively, compared to 37.9% in controls; P<0.05). In conclusion, caspofungin significantly improves oxidative burst and intracellular killing, which may be advantageous for clinical therapy...
  9. ncbi request reprint Efficacy of moxifloxacin, trovafloxacin, clinafloxacin and levofloxacin against intracellular Legionella pneumophila
    D Jonas
    National Reference Centre of Hygiene and Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetter Strasse 55, D 79106 Freiburg, Germany
    J Antimicrob Chemother 47:147-52. 2001
    ..These data strongly support further clinical evaluation of new fluoroquinolones for empirical treatment of lower respiratory tract infection including atypical pneumonia caused by L. pneumophila...
  10. doi request reprint Antimicrobial resistance in Escherichia coli strains isolated from food, animals and humans in Germany
    E Meyer
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Breisacher Str 115 b, 79106, Freiburg, Germany
    Infection 36:59-61. 2008
    ..coli strains originating from animals showed a higher resistance proportion to tetracycline...
  11. ncbi request reprint [Development of the Borderline Symptom List]
    M Bohus
    Abteilung für Psychiatrie und Psychotherapie mit Poliklinik der Albert Ludwigs Universität Freiburg
    Psychother Psychosom Med Psychol 51:201-11. 2001
    ..Factor analyses revealed seven factors: self-image, affect regulation, autoaggression, dysthymia, social isolation, intrusions and hostility. Analyses of reliability and validity revealed promising results...
  12. doi request reprint Bed occupancy rates and hospital-acquired infections--should beds be kept empty?
    K Kaier
    Department of Environmental Health Sciences, University Medical Centre Freiburg, Freiburg, Germany
    Clin Microbiol Infect 18:941-5. 2012
    ..Because the evidence on this topic is limited, we conclude that further research is needed in order to analyse the rationale of a threshold BO rate, because keeping beds empty is comparatively costly...
  13. doi request reprint Implementing strategic bundles for infection prevention and management
    K Kaier
    Department of Environmental Health Sciences, University Medical Center Freiburg, Freiburg, Germany
    Infection 40:225-8. 2012
    ..The general goal of this project is to provide evidence on how to decrease the incidence of HAI and to improve antibiotic use under routine conditions...
  14. ncbi request reprint Multicentre study of antimicrobial resistance and antibiotic consumption among 6,780 patients with bloodstream infections
    U Frank
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Freiburg, Germany
    Eur J Clin Microbiol Infect Dis 25:815-7. 2006
  15. doi request reprint Broad spectrum antibacterial activity of a mixture of isothiocyanates from nasturtium (Tropaeoli majoris herba) and horseradish (Armoraciae rusticanae radix)
    A Conrad
    Department of Environmental Health Sciences, University Medical Center Freiburg, Freiburg, Germany
    Drug Res (Stuttg) 63:65-8. 2013
    ..Low susceptibilities were determined for viridans streptococci and enterococci. Interestingly, both resistant and non-resistant bacteria were similarly susceptible to the test preparation...
  16. ncbi request reprint Effect of skin disinfection with octenidine dihydrochloride on insertion site colonization of intravascular catheters
    M Dettenkofer
    Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetter Str 55, D 79106 Freiburg, Germany
    Infection 30:282-5. 2002
    ..We investigated the efficacy of two commercially available, alcohol-based antiseptic solutions in decontaminating the insertion site of central lines. One solution contained the bispyridine octenidine dihydrochloride...
  17. doi request reprint Postoperative nosocomial endophthalmitis: is perioperative antibiotic prophylaxis advisable? A single centre's experience
    T Ness
    University Eye Hospital of Freiburg, Freiburg, Germany
    J Hosp Infect 78:138-42. 2011
    ....
  18. ncbi request reprint The need for macrolides in hospitalised community-acquired pneumonia: propensity analysis
    M Paul
    Department of Medicine E, Rabin Medical Center, Beilinson Hospital, 49100 Petah Tiqva, Israel
    Eur Respir J 30:525-31. 2007
    ..69 (95% confidence interval 0.32-1.48). The benefit of combination therapy versus monotherapy cannot be reliably assessed in observational studies, since the propensity to prescribe these regimens differs markedly...
  19. ncbi request reprint Activities of various beta-lactams and beta-lactam/beta-lactamase inhibitor combinations against Acinetobacter baumannii and Acinetobacter DNA group 3 strains
    J Brauers
    Antiinfectives Intelligence GmbH, Bonn, Germany
    Clin Microbiol Infect 11:24-30. 2005
    ..Testing with the inhibitor added at a fixed ratio of inhibitor to beta-lactam appeared to give more reliable results than testing at a fixed concentration of the inhibitor. Resistance to carbapenems (0.3%) remains low in Germany...
  20. ncbi request reprint Persistent silver disinfectant for the environment: myth and reality
    Armin Schuster
    Am J Infect Control 32:309; author reply 309-11. 2004
  21. ncbi request reprint Influence of an infectious disease consulting service on quality and costs of antibiotic prescriptions in a university hospital
    S W Lemmen
    , University Hospital Aachen, Germany
    Scand J Infect Dis 33:219-21. 2001
    ..These data show that an infectious disease consulting service optimizes antibiotic usage, and is cost-effective as a result of a significant cost reduction in hospitals, while not interfering with the quality of medical care...
  22. ncbi request reprint Cost-effectiveness of an antiseptic-impregnated central venous catheter in the ICU
    U Frank
    Intensive Care Med 29:139. 2003