A Erbersdobler

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint Pathological and clinical characteristics of large prostate cancers predominantly located in the transition zone
    A Erbersdobler
    Institute of Pathology, University of Hamburg, Germany
    Prostate Cancer Prostatic Dis 5:279-84. 2002
  2. ncbi request reprint Russell body gastritis: an unusual, tumor-like lesion of the gastric mucosa
    Andreas Erbersdobler
    Department of Pathology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Arch Pathol Lab Med 128:915-7. 2004
  3. ncbi request reprint A validated strategy for side specific prediction of organ confined prostate cancer: a tool to select for nerve sparing radical prostatectomy
    M Graefen
    Department of Urology and Institutes of Mathematics and Computer Science in Medicine, and Pathology University Hospital Eppendorf, Hamburg, Germany
    J Urol 165:857-63. 2001
  4. ncbi request reprint Significance of high-grade prostatic intraepithelial neoplasia in needle biopsy specimens
    W Prange
    Institute of Pathology, University Hospital Eppendorf, University of Hamburg, Hamburg, Germany
    Urology 57:486-90. 2001
  5. ncbi request reprint Transition zone cancers undermine the predictive accuracy of Partin table stage predictions
    T Steuber
    Department of Urology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Urol 173:737-41. 2005
  6. ncbi request reprint Relevance of p53 gene alterations for tumor recurrence in patients with superficial transitional cell carcinoma of the bladder
    M G Friedrich
    Department of Urology, University of Hamburg, University Hospital Eppendorf, Germany
    Eur Urol 39:159-66. 2001
  7. ncbi request reprint Differences in biopsy features between prostate cancers located in the transition and peripheral zone
    H Augustin
    Department of Urology, University Hospital Hamburg Eppendorf, Germany
    BJU Int 91:477-81. 2003
  8. doi request reprint Prognostic relevance of Bcl-2 overexpression in surgically treated prostate cancer is not caused by increased copy number or translocation of the gene
    A Fleischmann
    Department of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Prostate 72:991-7. 2012
  9. ncbi request reprint [Primary squamous cell carcinoma of the liver. Surprising findings in dysontogenetic liver cysts]
    K Steffani
    Klinik und Poliklinik für Allgemein, Viszeral und Thoraxchirurgie, Universitatsklinikum Hamburg Eppendorf
    Dtsch Med Wochenschr 128:1947-50. 2003
  10. ncbi request reprint [Can nomograms derived in the U.S. applied to German patients? A study about the validation of preoperative nomograms predicting the risk of recurrence after radical prostatectomy]
    M Graefen
    Klinik und Poliklinik fur Urologie, Universitätsklinik Hamburg Eppendorf
    Urologe A 42:685-92. 2003

Collaborators

Detail Information

Publications75

  1. ncbi request reprint Pathological and clinical characteristics of large prostate cancers predominantly located in the transition zone
    A Erbersdobler
    Institute of Pathology, University of Hamburg, Germany
    Prostate Cancer Prostatic Dis 5:279-84. 2002
    ..8% of these patients suffered from postoperative PSA-recurrence. We conclude that the peculiar pathological and clinical characteristics of large prostate cancers in the transition zone might be important for prognostic considerations...
  2. ncbi request reprint Russell body gastritis: an unusual, tumor-like lesion of the gastric mucosa
    Andreas Erbersdobler
    Department of Pathology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Arch Pathol Lab Med 128:915-7. 2004
    ..However, immunohistochemistry confirmed a polyclonal pattern of the plasma cells. This unusual reactive lesion of the gastric mucosa has only rarely been described and has been termed Russell body gastritis...
  3. ncbi request reprint A validated strategy for side specific prediction of organ confined prostate cancer: a tool to select for nerve sparing radical prostatectomy
    M Graefen
    Department of Urology and Institutes of Mathematics and Computer Science in Medicine, and Pathology University Hospital Eppendorf, Hamburg, Germany
    J Urol 165:857-63. 2001
    ..Side specific analysis of these parameters is a flexible and reliable tool for selecting patients for nerve sparing radical prostatectomy...
  4. ncbi request reprint Significance of high-grade prostatic intraepithelial neoplasia in needle biopsy specimens
    W Prange
    Institute of Pathology, University Hospital Eppendorf, University of Hamburg, Hamburg, Germany
    Urology 57:486-90. 2001
    ..Its value in predicting a significantly increased risk of concurrent prostate cancer needs to be further investigated in larger case studies...
  5. ncbi request reprint Transition zone cancers undermine the predictive accuracy of Partin table stage predictions
    T Steuber
    Department of Urology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Urol 173:737-41. 2005
    ..We tested the predictive accuracy and performance of the Partin tables according to TZ vs PZ tumor predominance...
  6. ncbi request reprint Relevance of p53 gene alterations for tumor recurrence in patients with superficial transitional cell carcinoma of the bladder
    M G Friedrich
    Department of Urology, University of Hamburg, University Hospital Eppendorf, Germany
    Eur Urol 39:159-66. 2001
    ..The results of this molecular analysis were compared with accumulation of the p53 protein as shown by immunohistochemistry...
  7. ncbi request reprint Differences in biopsy features between prostate cancers located in the transition and peripheral zone
    H Augustin
    Department of Urology, University Hospital Hamburg Eppendorf, Germany
    BJU Int 91:477-81. 2003
    ....
  8. doi request reprint Prognostic relevance of Bcl-2 overexpression in surgically treated prostate cancer is not caused by increased copy number or translocation of the gene
    A Fleischmann
    Department of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Prostate 72:991-7. 2012
    ..The relation of Bcl-2 overexpression and copy number gains or translocation of the BCL-2 gene in prostate cancer under hormone-naïve conditions is unknown...
  9. ncbi request reprint [Primary squamous cell carcinoma of the liver. Surprising findings in dysontogenetic liver cysts]
    K Steffani
    Klinik und Poliklinik für Allgemein, Viszeral und Thoraxchirurgie, Universitatsklinikum Hamburg Eppendorf
    Dtsch Med Wochenschr 128:1947-50. 2003
    ..A 60-year-old woman presented with intermittent fever and pain in the right upper abdomen. The patient had spent the last 30 years in the Middle East and Africa...
  10. ncbi request reprint [Can nomograms derived in the U.S. applied to German patients? A study about the validation of preoperative nomograms predicting the risk of recurrence after radical prostatectomy]
    M Graefen
    Klinik und Poliklinik fur Urologie, Universitätsklinik Hamburg Eppendorf
    Urologe A 42:685-92. 2003
    ..0274). For that reason preoperative nomograms derived in the U.S. can be applied to german patients. However, we would recommend the utilization of the Kattan nomogram due to its higher predictive accuracy...
  11. ncbi request reprint [Dysfunction of a kidney allograft with life-threatening results]
    S Harendza
    Medizinische Klinik IV, Universitatsklinikum Hamburg Eppendorf
    Internist (Berl) 45:592-6. 2004
    ..Therapeutic options are reduction of the immunosuppression, chemotherapy or radiation, administration of lymphocyte-specific antibodies or removal of the kidney allograft...
  12. ncbi request reprint Multifocal distribution of pulmonary capillary haemangiomatosis
    A Erbersdobler
    Institute of Pathology, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Histopathology 40:88-91. 2002
    ..We investigated a case of pulmonary capillary haemangiomatosis, a rare condition, to determine the extent of the pathological changes within the lungs. Systematic histological sampling has not previously been performed in this condition...
  13. ncbi request reprint Simultaneous tumour-like, atypical basal cell hyperplasia and acinar adenocarcinoma of the prostate: a comparative morphological and genetic approach
    A M Luebke
    Department of Urology, University of Hamburg, Martinistrasse 52, 22081 Hamburg, Germany
    Virchows Arch 446:338-41. 2005
    ..The pathological findings favoured the diagnosis of an atypical basal cell hyperplasia...
  14. ncbi request reprint Frequent p16/MTS1 inactivation in early stages of urothelial carcinoma of the bladder is not associated with tumor recurrence
    M G Friedrich
    Department of Urology, University of Hamburg, University Hospital Eppendorf, Germany
    Eur Urol 40:518-24. 2001
    ..We investigated 40 patients with Ta, T1 TCC of the bladder for p16 alterations (mutations, homozygote deletions, allelic loss) or reduced p16 immunoreaction...
  15. ncbi request reprint Expression of 17-1A antigen and complement resistance factors CD55 and CD59 on liver metastasis in colorectal cancer
    S B Hosch
    Department of General Surgery, University of Hamburg, Hamburg, Germany
    J Gastrointest Surg 5:673-9. 2001
    ..Therefore patients with completely resected liver metastases might be suitable candidates for adjuvant therapy with and-17-1A antibody since only a few of these lesions showed coexpression of complement resistance factors...
  16. doi request reprint Microsatellite analysis of allelic imbalance in tumour and blood from patients with prostate cancer
    Heidi Schwarzenbach
    Institute of Tumour Biology, University Medical Centre, Hamburg Eppendorf, Germany
    BJU Int 102:253-8. 2008
    ..To investigate whether a high frequency of allelic imbalance (AI) is associated with clinicopathological variables of patients with prostate cancer...
  17. ncbi request reprint Development and external validation of an extended 10-core biopsy nomogram
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Eur Urol 52:436-44. 2007
    ..To test the accuracy of a previously externally validated sextant biopsy nomogram in referred men exposed to > or =10 or more biopsy cores. Moreover, we explored the hypothesis that a more accurate predictive tool could be developed...
  18. ncbi request reprint Body mass index does not improve the ability to predict biochemical recurrence after radical prostatectomy
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre CHUM, 1058, rue St Denis, Montreal, Quebec H2X 3J4, Canada
    Eur J Cancer 43:375-82. 2007
    ..To test whether body mass index (BMI) improves pre- or post-operative biochemical recurrence (BCR) predictions after radical prostatectomy...
  19. ncbi request reprint Surgical volume is related to the rate of positive surgical margins at radical prostatectomy in European patients
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    BJU Int 98:1204-9. 2006
    ..To assess the association between surgical volume (SV) and the rate of positive surgical margins (PSM) after radical prostatectomy (RP) in a large single-institution European cohort of patients...
  20. ncbi request reprint Strong prognostic value of nodal and bone marrow micro-involvement in patients with pancreatic ductal carcinoma receiving no adjuvant chemotherapy
    Emre F Yekebas
    Department of General, Visceral and Thoracic Surgery, University Medical Centre of Hamburg Eppendorf, Martinistrabe 52, 20246 Hamburg, Germany
    World J Gastroenterol 12:6515-21. 2006
    ..To study the prognostic value of adjuvant chemotherapy in patients with pancreatic, ductal adenocarcinoma...
  21. ncbi request reprint Circulating tumour-associated plasma DNA represents an independent and informative predictor of prostate cancer
    Felix K H Chun
    Department of Urology, University Hospital Hamburg Epppendorf, Hamburg, Germany
    BJU Int 98:544-8. 2006
    ..To investigate whether preoperative plasma levels of free DNA can discriminate between men with localized prostate cancer and benign prostatic hyperplasia (BPH)...
  22. ncbi request reprint Significant upgrading affects a third of men diagnosed with prostate cancer: predictive nomogram and internal validation
    Felix K H Chun
    Department of Urology, University of Hamburg, Hamburg, Germany
    BJU Int 98:329-34. 2006
    ....
  23. ncbi request reprint Nerve distribution along the prostatic capsule
    Christian Eichelberg
    Department of Urology, University Hospital Eppendorf, Hamburg, Germany
    Eur Urol 51:105-10; discussion 110-1. 2007
    ..The objective of this study therefore was to determine the typical pattern of nerve distribution along the prostatic capsule...
  24. pmc Ep-CAM expression in squamous cell carcinoma of the esophagus: a potential therapeutic target and prognostic marker
    Nikolas H Stoecklein
    Klinik für Allgemein und Viszeralchirurgie, Universitatsklinikum Dusseldorf, D 40225 Dusseldorf, Germany
    BMC Cancer 6:165. 2006
    ....
  25. ncbi request reprint High incidence of prostate cancer detected by saturation biopsy after previous negative biopsy series
    Jochen Walz
    Department of Urology, University Medical Centre Eppendorf, Hamburg, Germany
    Eur Urol 50:498-505. 2006
    ..We explored the yield of saturation biopsy and developed a nomogram predicting the probability of prostate cancer (PCa) on the basis of saturation biopsy...
  26. ncbi request reprint Frozen section for the management of intraoperatively detected palpable tumor lesions during nerve-sparing scheduled radical prostatectomy
    Christian Eichelberg
    Department of Urology, University Hospital Hamburg Eppendorf, Germany
    Eur Urol 49:1011-6; discussion 1016-8. 2006
    ..We investigated the use of frozen section (FS) analysis to monitor the safety and efficiency of NS during RP in patients with intraoperatively identified subcapsular tumor lesions...
  27. ncbi request reprint Validation of a nomogram for prediction of side specific extracapsular extension at radical prostatectomy
    Thomas Steuber
    Department of Urology, Hamburg, Germany
    J Urol 175:939-44; discussion 944. 2006
    ..We developed a nomogram and compared the performance and discriminant properties of the tree regression and the nomogram in a contemporary cohort of European patients treated with radical retropubic prostatectomy...
  28. doi request reprint Currently used criteria for active surveillance in men with low-risk prostate cancer: an analysis of pathologic features
    Nazareno Suardi
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Cancer 113:2068-72. 2008
    ..In this report, the authors addressed the rates of misclassification associated with the use of 5 different clinical criteria for AS. Misclassification was defined as the presence of either nonorgan-confined disease or high-grade PCa...
  29. ncbi request reprint Development and internal validation of preoperative transition zone prostate cancer nomogram
    Thomas Steuber
    Department of Urology, University of Hamburg, Hamburg, Germany
    Urology 68:1295-300. 2006
    ..TZ PCa may be associated with more favorable RP pathologic findings than peripheral zone (PZ) PCa. To identify these men, we developed a model capable of predicting the probability of TZ PCa at RP...
  30. ncbi request reprint Clinical significance of epidermal growth factor receptor protein overexpression and gene copy number gains in prostate cancer
    Thorsten Schlomm
    Martini Clinic, Prostate Cancer Center, Department of Pathology and Urology, University Medical Center Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
    Clin Cancer Res 13:6579-84. 2007
    ..To determine its role in prostate cancer, we analyzed 2,497 prostate cancers on the DNA and protein level...
  31. ncbi request reprint Effect of autologous blood transfusion on the rate of biochemical recurrence after radical prostatectomy
    Andrea Gallina
    Department of Urology, Vita Salute University San Raffaele, Milan, Italy
    BJU Int 100:1249-53. 2007
    ..To test the association between autologous blood transfusion (ABT) and biochemical recurrence (BCR) after radical prostatectomy (RP) in a large group of contemporary patients...
  32. ncbi request reprint Obesity does not predispose to more aggressive prostate cancer either at biopsy or radical prostatectomy in European men
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Int J Cancer 121:791-5. 2007
    ..7%, p = 0.6; InvBMI gain = 0.5, p = 0.7%). Obesity does not predispose to more aggressive prostate cancer at biopsy. Similarly, obesity does not change the ability to identify those who may harbor HGPCa at RP...
  33. doi request reprint Biopsies performed at tertiary care centers are superior to referral biopsies in predicting pathologic Gleason sum
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Endourol 22:533-8. 2008
    ..Biopsy grading at tertiary care centers may or may not be superior to biopsies performed at referral institutions...
  34. ncbi request reprint Marked gene transcript level alterations occur early during radical prostatectomy
    Thorsten Schlomm
    Martini Clinic, Prostate Cancer Center, University Medical Center, Hamburg Eppendorf, Germany
    Eur Urol 53:333-44. 2008
    ..However, transcript level patterns and RNA quality could rapidly change in response to ischemic and mechanical stress. Studies have shown that this occurs both perioperatively and after surgical removal of organs...
  35. ncbi request reprint Health-insurance status is a determinant of the stage at presentation and of cancer control in European men treated with radical prostatectomy for clinically localized prostate cancer
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    BJU Int 99:1404-8. 2007
    ....
  36. doi request reprint Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer
    Nikolas H Stoecklein
    Department of Pathology, Division of Oncogenomics, University of Regensburg, D 93053 Regensburg, Germany
    Cancer Cell 13:441-53. 2008
    ..Survival analysis demonstrated that HER2 gain in a single disseminated tumor cell but not in primary tumors conferred high risk for early death...
  37. ncbi request reprint Molecular staging of prostate cancer in the year 2007
    Thorsten Schlomm
    Martini Clinic, Prostate Cancer Center, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    World J Urol 25:19-30. 2007
    ..for optimal clinical decision making in prostate cancer patients: which patients will not require local therapy? If local therapy is needed, what is the treatment of choice? What medications should be given if metastases are present?..
  38. ncbi request reprint Development and split-sample validation of a nomogram predicting the probability of seminal vesicle invasion at radical prostatectomy
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Eur Urol 52:98-105. 2007
    ..We hypothesized that contemporary patients, at very low risk of seminal vesicle invasion (SVI), can be highly accurately identified with an equally contemporary SVI nomogram...
  39. doi request reprint Critical assessment of tools to predict clinically insignificant prostate cancer at radical prostatectomy in contemporary men
    Felix K H Chun
    Department of Urology, University of Hamburg, Hamburg, Germany
    Cancer 113:701-9. 2008
    ..Overtreatment of prostate cancer (PCa) is a concern, especially in patients who might qualify for the diagnosis of insignificant prostate cancer (IPCa). The ability to identify IPCa prior to definitive therapy was tested...
  40. ncbi request reprint Development and external validation of an extended repeat biopsy nomogram
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Urol 177:510-5. 2007
    ..We hypothesized that the outcome of repeat biopsy could be accurately predicted. We tested this hypothesis in a contemporary cohort from 3 centers...
  41. ncbi request reprint Tumour volume and high grade tumour volume are the best predictors of pathologic stage and biochemical recurrence after radical prostatectomy
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center CHUM, 1058, rue St Denis, Montreal, Que, Canada H2X 3J4
    Eur J Cancer 43:536-43. 2007
    ..Our goal was to examine to what extent tumour volume (TV) and percentage of high grade tumour volume (%HGTV) affect the rate of positive surgical margins and the rate of biochemical recurrence after radical prostatectomy...
  42. ncbi request reprint Detection of tumor-specific DNA in blood and bone marrow plasma from patients with prostate cancer
    Heidi Schwarzenbach
    Institute of Tumor Biology, University Medical Center Hamburg Eppendorf, Germany
    Int J Cancer 120:1465-71. 2007
    ..These data demonstrate, for the first time, the presence of free tumor-specific DNA in blood and BM of PCa patients and suggest a possible relationship to BM micrometastasis...
  43. ncbi request reprint Determination of microvessel density by quantitative real-time PCR in esophageal cancer: correlation with histologic methods, angiogenic growth factor expression, and lymph node metastasis
    Sonja Loges
    Department of Internal Medicine II, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Clin Cancer Res 13:76-80. 2007
    ..We compared MVD determination by immunohistology and quantitative real-time PCR and correlated the results with clinical variables...
  44. ncbi request reprint Development and internal validation of a nomogram predicting the probability of prostate cancer Gleason sum upgrading between biopsy and radical prostatectomy pathology
    Felix K H Chun
    Department of Urology, University of Hamburg, Hamburg, Germany
    Eur Urol 49:820-6. 2006
    ..We explored the rate of upgrading from biopsy to RP specimen in our contemporary cohort, and developed a model capable of predicting the probability of biopsy Gleason sum upgrading...
  45. ncbi request reprint The 2002 AJCC pT2 substages confer no prognostic information on the rate of biochemical recurrence after radical prostatectomy
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit and the Department of Urology, University of Montreal Health Center, Montreal, Canada
    Eur Urol 49:273-8; discussion 278-9. 2006
    ..We examined the prognostic value of AJCC pT2 substages in prediction of biochemical recurrence (BCR) after radical prostatectomy (RP), in European patients...
  46. ncbi request reprint Comparative assessment of the 1992 and 2002 pathologic T3 substages for the prediction of biochemical recurrence after radical prostatectomy
    Thomas Steuber
    Department of Urology, University Hospital Hamburg Eppendorf, Germany
    Cancer 106:775-82. 2006
    ....
  47. ncbi request reprint Characterisation of biomolecular profiles in primary high-grade prostate cancer treated by radical prostatectomy
    Herbert Augustin
    Department of Urology, Karl Franzens University Graz, Auenbruggerplatz 7, 8036 Graz, Austria
    J Cancer Res Clin Oncol 129:662-8. 2003
    ..The aim of this study was to compare the biomolecular profile of high-grade (HG) with low-grade (LG) prostate cancers matched by preoperative serum prostate-specific antigen (PSA) levels...
  48. ncbi request reprint Prognostic significance of visible lesions on transrectal ultrasound in impalpable prostate cancers: implications for staging
    Herbert Augustin
    Department of Urology, University of Hamburg, Hamburg, Germany
    J Clin Oncol 21:2860-8. 2003
    ..The aim of this article is to provide a differentiated view of the significance of TRUS findings for staging purposes in impalpable prostate cancers...
  49. ncbi request reprint Zonal location of prostate cancer: significance for disease-free survival after radical prostatectomy?
    Herbert Augustin
    Department of Urology, University Hospital Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
    Urology 62:79-85. 2003
    ..To analyze the zonal location of prostate cancer as a possible predictive feature of progression-free survival after radical prostatectomy...
  50. ncbi request reprint Insignificant prostate cancer in radical prostatectomy specimen: time trends and preoperative prediction
    Herbert Augustin
    Department of Urology, University Hospital Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
    Eur Urol 43:455-60. 2003
    ..5 cm(3) and Gleason pattern < or =6)...
  51. ncbi request reprint Biochemical recurrence following radical prostatectomy: a comparison between prostate cancers located in different anatomical zones
    Herbert Augustin
    Department of Urology, University Hospital Hamburg Eppendorf, University of Hamburg, Martinistrasse 52, D 20246 Hamburg, Germany
    Prostate 55:48-54. 2003
    ..To assess whether differences of biochemical recurrence after radical prostatectomy exist between prostate cancers located in the transition zone (TZ) and peripheral zone (PZ)...
  52. ncbi request reprint Can predictive models for prostate cancer patients derived in the United States of America be utilized in European patients? A validation study of the Partin tables
    Markus Graefen
    Department of Urology, University Hospital Hamburg Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Eur Urol 43:6-10; discussion 11. 2003
    ..Accuracy of predictive tools derived in the US might therefore suffer when applied to European patients. We tested the validity of the widely accepted Partin tables for their ability to predict pathologic stage in German patients...
  53. ncbi request reprint A validation of two preoperative nomograms predicting recurrence following radical prostatectomy in a cohort of European men
    Markus Graefen
    Departments of Urology and Pathology, University Hospital, Hamburg Eppendorf, Germany
    Urol Oncol 7:141-6. 2002
    ..The high predictive accuracy of both nomograms demonstrates that these predictive tools derived in the U.S. can be applied to non-U.S. patients...
  54. ncbi request reprint Impact of different modalities of continuous venovenous hemofiltration on sepsis-induced alterations in experimental pancreatitis
    Emre F Yekebas
    Department of Surgery, University Hospital Eppendorf, Hamburg, Germany
    Kidney Int 62:1806-18. 2002
    ..The impact of different treatment intensities of CVVH on immunologic and systemic alterations in experimental pancreatitis was evaluated...
  55. ncbi request reprint International validation of a preoperative nomogram for prostate cancer recurrence after radical prostatectomy
    Markus Graefen
    Department of Urology, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    J Clin Oncol 20:3206-12. 2002
    ..We applied this nomogram to patients from seven different institutions spanning three continents...
  56. ncbi request reprint Prediction of tumor heterogeneity in localized prostate cancer
    Hartwig Huland
    Department of Urology, University Clinics Hamburg Eppendorf, Martinistrasse 52, D 20246, Hamburg, Germany
    Urol Clin North Am 29:213-22. 2002
    ..Clinical T1 or T2 prostatic carcinoma is a heterogeneous but fairly predictable tumor...
  57. ncbi request reprint Assessment of clinical and pathologic characteristics predisposing to disease recurrence following radical prostatectomy in men with pathologically organ-confined prostate cancer
    R Jüri Palisaar
    Department of Urology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 41:155-61. 2002
    ..To identify risk factors for biochemical failure after radical prostatectomy (RP) in men with pathologically organ-confined (OC) prostate cancer (PCa)...
  58. ncbi request reprint Tumour grade, proliferation, apoptosis, microvessel density, p53, and bcl-2 in prostate cancers: differences between tumours located in the transition zone and in the peripheral zone
    Andreas Erbersdobler
    Institute of Pathology, University of Hamburg, Germany
    Eur Urol 41:40-6. 2002
    ..It is unclear, however, whether this can be put down to anatomical reasons alone, or if there are further differences between tumours of both zones...
  59. ncbi request reprint Analysis of clinical stage T2 prostate cancer: do current subclassifications represent an improvement?
    Ilias Cagiannos
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, NY 11021, USA
    J Clin Oncol 20:2025-30. 2002
    ..The purpose of this study was to determine whether the extent of palpable cancer within the prostate predicts outcome after radical prostatectomy...
  60. ncbi request reprint Counseling men with prostate cancer: a nomogram for predicting the presence of small, moderately differentiated, confined tumors
    Michael W Kattan
    Department of Urology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    J Urol 170:1792-7. 2003
    ....
  61. ncbi request reprint A preoperative nomogram identifying decreased risk of positive pelvic lymph nodes in patients with prostate cancer
    Ilias Cagiannos
    Department of Urology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    J Urol 170:1798-803. 2003
    ..We developed a preoperative nomogram for prediction of lymph node metastases in patients with clinically localized prostate cancer...
  62. ncbi request reprint Detection of human telomerase RNA in the tumour-surrounding mucosa of bladder carcinomas as a marker for premalignant transformation
    Sven Leuenroth
    Institute of Pathology, University Hospital Hamburg Eppendorf, University of Hamburg, Germany
    BJU Int 96:553-7. 2005
    ..To investigate tumour tissue and non-malignant tumour-surrounding bladder mucosa (NTSBM) for expression of human telomerase RNA (hTR) as a possible marker for premalignant transformation of urothelial cells...
  63. ncbi request reprint Extraction and processing of high quality RNA from impalpable and macroscopically invisible prostate cancer for microarray gene expression analysis
    Thorsten Schlomm
    Department of Urology, University Clinic Hamburg Eppendorf, D 20246 Hamburg, Germany
    Int J Oncol 27:713-20. 2005
    ..Among these were several known prostate cancer relevant genes, such as AMACR, TARP, LIM, GPR160 (all up-regulated), CAV1, NTN1, MT1X; CLU, TRIM29, SPARCL1 and HSPB8 (all down-regulated)...
  64. ncbi request reprint Influence of nerve-sparing (NS) procedure during radical prostatectomy (RP) on margin status and biochemical failure
    Rein Jüri Palisaar
    Department of Urology, University Clinics of Bochum, Marienhospital Herne, 44627 Herne, Germany
    Eur Urol 47:176-84. 2005
    ..To evaluate whether nerve-sparing procedure itself is a risk factor for biochemical recurrence in carefully selected patients...
  65. ncbi request reprint Prostate cancers in the transition zone: Part 2; clinical aspects
    Herbert Augustin
    Department of Urology, University of Graz, Austria
    BJU Int 94:1226-9. 2004
  66. ncbi request reprint Prostate cancers in the transition zone: Part 1; pathological aspects
    Andreas Erbersdobler
    Institute of Pathology, University of Hamburg, Hamburg, Germany
    BJU Int 94:1221-5. 2004
  67. pmc Mode of spread in the early phase of lymphatic metastasis in pancreatic ductal adenocarcinoma: prognostic significance of nodal microinvolvement
    Dean Bogoevski
    Department of General, Visceral and Thoracic Surgery, University Medical Centre of Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Ann Surg 240:993-1000; discussion 1000-1. 2004
    ..The aim of this study was to assess the prognostic significance of nodal microinvolvement as well as the mode of spread in the early phase of lymphatic metastasis in patients with node-negative pancreatic ductal adenocarcinoma...
  68. ncbi request reprint Copy number of chromosome 17 but not HER2 amplification predicts clinical outcome of patients with pancreatic ductal adenocarcinoma
    Nikolas H Stoecklein
    Chirurgische Klinik, and Institut für Pathologie, Universitatsklinikum Hamburg Eppendorf, Hamburg, Germany
    J Clin Oncol 22:4737-45. 2004
    ..To determine the frequency and the potential clinical use of HER2 (17q21) gene amplification and chromosome 17 aneuploidy in pancreatic ductal adenocarcinoma (PDAC)...
  69. ncbi request reprint Association of free-prostate specific antigen subfractions and human glandular kallikrein 2 with volume of benign and malignant prostatic tissue
    Thomas Steuber
    Department of Urology, University of Hamburg Eppendorf, Hamburg, Germany
    Prostate 63:13-8. 2005
    ....
  70. ncbi request reprint Expression of Maspin in non-muscle invasive bladder carcinoma: correlation with tumor angiogenesis and prognosis
    Martin G Friedrich
    Department of Urology, University of Hamburg, University Hospital Hamburg Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Eur Urol 45:737-43. 2004
    ..We studied expression patterns of Maspin in pTa/pT1 urothelial carcinoma of the bladder and compared them with microvessel density (MVD) for two vascular markers (CD34 and CD105) and correlated the findings with clinical outcome...
  71. ncbi request reprint Gain of androgen receptor gene copies in primary prostate cancer due to X chromosome polysomy
    Albrecht Röpke
    Institute of Human Genetics, Otto von Guericke University Magdeburg, Germany
    Prostate 59:59-68. 2004
    ..In this study prostatectomy specimens from patients without preoperative therapy were analyzed to determine the possible mechanism of primary antiandrogen resistance...
  72. ncbi request reprint Assessment of the enhancement in predictive accuracy provided by systematic biopsy in predicting outcome for clinically localized prostate cancer
    Markus Graefen
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    J Urol 171:200-3. 2004
    ..We investigated whether the addition of prostate biopsy features may enhance the accuracy of a nomogram predicting recurrence after radical prostatectomy (RP)...
  73. ncbi request reprint Extensive cerebral metastases from neuroendocrine carcinoma of the prostate
    Jakob Matschke
    Virchows Arch 444:202-3. 2004
  74. ncbi request reprint Total and Gleason grade 4/5 cancer volumes are major contributors of human kallikrein 2, whereas free prostate specific antigen is largely contributed by benign gland volume in serum from patients with prostate cancer or benign prostatic biopsies
    Alexander Haese
    Department of Urology, University Clinic Eppendorf, Hamburg, Germany
    J Urol 170:2269-73. 2003
    ....
  75. ncbi request reprint Prospective validation of an algorithm with systematic sextant biopsy to predict pelvic lymph node metastasis in patients with clinically localized prostatic carcinoma
    Stefan Conrad
    Department of Urology, Institute of Mathematics and Computer Science in Medicine, University of Hamburg, Eppendorf University Hospital, Hamburg, Germany
    J Urol 167:521-5. 2002
    ..We prospectively validate an algorithm to predict pelvic lymph node metastasis in patients with clinically localized prostatic carcinoma...