Sebastian J Buss

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. doi request reprint Classification of diastolic function with phase-contrast cardiac magnetic resonance imaging: validation with echocardiography and age-related reference values
    Sebastian J Buss
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, 69120, Germany
    Clin Res Cardiol 103:441-50. 2014
  2. doi request reprint Quantitative analysis of left ventricular strain using cardiac computed tomography
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, 69120 Heidelberg, Germany Electronic address
    Eur J Radiol 83:e123-30. 2014
  3. doi request reprint Rapid assessment of longitudinal systolic left ventricular function using speckle tracking of the mitral annulus
    Sebastian J Buss
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany
    Clin Res Cardiol 101:273-80. 2012
  4. doi request reprint Myocardial left ventricular dysfunction in patients with systemic lupus erythematosus: new insights from tissue Doppler and strain imaging
    Sebastian J Buss
    Department of Cardiology, Angiology and Pulmology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Rheumatol 37:79-86. 2010
  5. doi request reprint Echocardiographic phase imaging to predict reverse remodeling after cardiac resynchronization therapy
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    JACC Cardiovasc Imaging 2:535-43. 2009
  6. doi request reprint Longitudinal left ventricular function for prediction of survival in systemic light-chain amyloidosis: incremental value compared with clinical and biochemical markers
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 60:1067-76. 2012
  7. doi request reprint Autoimmunity against cardiac troponin I in ischaemia reperfusion injury
    H Christian Volz
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    Eur J Heart Fail 13:1052-9. 2011
  8. ncbi request reprint Augmentation of autophagy by mTOR-inhibition in myocardial infarction: When size matters
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Autophagy 6:304-6. 2010
  9. doi request reprint Galectin-3 binding protein plasma levels are associated with long-term mortality in coronary artery disease independent of plaque morphology
    Christian A Gleissner
    Department of Cardiology, University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany DZHK German Centre for Cardiovascular Research, partner site Heidelberg, Germany Electronic address
    Atherosclerosis 251:94-100. 2016
  10. doi request reprint Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 54:2435-46. 2009

Collaborators

Detail Information

Publications53

  1. doi request reprint Classification of diastolic function with phase-contrast cardiac magnetic resonance imaging: validation with echocardiography and age-related reference values
    Sebastian J Buss
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, 69120, Germany
    Clin Res Cardiol 103:441-50. 2014
    ..To investigate whether cardiac magnetic resonance phase-contrast imaging (PC-CMR) can determine left ventricular (LV) diastolic function in comparison to echocardiography (EC)...
  2. doi request reprint Quantitative analysis of left ventricular strain using cardiac computed tomography
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, 69120 Heidelberg, Germany Electronic address
    Eur J Radiol 83:e123-30. 2014
    ....
  3. doi request reprint Rapid assessment of longitudinal systolic left ventricular function using speckle tracking of the mitral annulus
    Sebastian J Buss
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany
    Clin Res Cardiol 101:273-80. 2012
    ..Left ventricular longitudinal function has been recognized to differentiate myocardial disorders better than ejection fraction (EF) alone. But recent parameters are still dependent on image quality and time consuming...
  4. doi request reprint Myocardial left ventricular dysfunction in patients with systemic lupus erythematosus: new insights from tissue Doppler and strain imaging
    Sebastian J Buss
    Department of Cardiology, Angiology and Pulmology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Rheumatol 37:79-86. 2010
    ..Our aim was to determine if new echocardiographic imaging modalities like tissue Doppler (TDI), strain rate (SRR), and strain (SRI) imaging detect abnormalities in left ventricular (LV) function in asymptomatic patients with SLE...
  5. doi request reprint Echocardiographic phase imaging to predict reverse remodeling after cardiac resynchronization therapy
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    JACC Cardiovasc Imaging 2:535-43. 2009
    ..The aim of our study was to investigate whether echocardiographic phase imaging (EPI) can predict response in patients who are considered for cardiac resynchronization therapy (CRT)...
  6. doi request reprint Longitudinal left ventricular function for prediction of survival in systemic light-chain amyloidosis: incremental value compared with clinical and biochemical markers
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 60:1067-76. 2012
    ..The aim of the study was to determine whether longitudinal left ventricular (LV) function provides prognostic information in a large cohort of patients with systemic light-chain (AL) amyloidosis...
  7. doi request reprint Autoimmunity against cardiac troponin I in ischaemia reperfusion injury
    H Christian Volz
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    Eur J Heart Fail 13:1052-9. 2011
    ..Furthermore, we studied the effects of cTnI-autoimmunity on the infarcted myocardium following revascularization measures in terms of ischaemia reperfusion injury (IRI), which resembles clinical reality more closely...
  8. ncbi request reprint Augmentation of autophagy by mTOR-inhibition in myocardial infarction: When size matters
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Autophagy 6:304-6. 2010
    ..The induction of autophagy via mTOR inhibition is a novel potential therapeutic approach to limit infarct size and to attenuate adverse left ventricular remodeling following MI...
  9. doi request reprint Galectin-3 binding protein plasma levels are associated with long-term mortality in coronary artery disease independent of plaque morphology
    Christian A Gleissner
    Department of Cardiology, University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany DZHK German Centre for Cardiovascular Research, partner site Heidelberg, Germany Electronic address
    Atherosclerosis 251:94-100. 2016
    ..We hypothesized that high Gal-3BP levels may indicate unfavorable plaque morphology and outcome in coronary artery disease (CAD)...
  10. doi request reprint Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    J Am Coll Cardiol 54:2435-46. 2009
    ..In this study we investigated whether inhibition of "mammalian target of rapamycin" (mTOR) attenuates left ventricular (LV) remodeling after MI...
  11. doi request reprint Depletion of mammalian target of rapamycin (mTOR) via siRNA mediated knockdown leads to stabilization of beta-catenin and elicits distinct features of cardiomyocyte hypertrophy
    Marco Hagenmueller
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    FEBS Lett 584:74-80. 2010
    ..Our findings suggest a new type of convergence of mTOR and GSK3beta activities, indicating that GSK3beta-dependent stabilization of beta-catenin in cardiac myocytes is influenced by mTOR...
  12. doi request reprint Activation of PPARgamma by pioglitazone does not attenuate left ventricular hypertrophy following aortic banding in rats
    Celine S Weiss
    Department of Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg Germany
    Naunyn Schmiedebergs Arch Pharmacol 381:285-95. 2010
    ..The findings rather indicate a pro-hypertrophic effect of pioglitazone treatment after aortic banding...
  13. ncbi request reprint Differential expression of cardiac neurotrophic factors and sympathetic nerve ending abnormalities within the failing heart
    Michael M Kreusser
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Mol Cell Cardiol 44:380-7. 2008
    ..In conclusion, during the development of CHF, a dysregulated NE storage/release/uptake apparatus within the sympathetic nerve endings might be triggered by differential expression of cardiac neurotrophic factors...
  14. ncbi request reprint Left ventricular mechanics assessed by two-dimensional echocardiography and cardiac magnetic resonance imaging: comparison of high-resolution speckle tracking and feature tracking
    Matthias Aurich
    Department of Internal Medicine III, Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany
    Eur Heart J Cardiovasc Imaging . 2016
    ..We aimed to evaluate different methods for quantification of LV strain on global and regional levels with a focus on the new non-proprietary feature tracking (FT) algorithm...
  15. pmc Left ventricular long axis strain: a new prognosticator in non-ischemic dilated cardiomyopathy?
    Johannes H Riffel
    Department of Cardiology, University of Heidelberg, INF 410, 69120, Heidelberg, Germany
    J Cardiovasc Magn Reson 18:36. 2016
    ..However, the prognostic value of LAS in cardiomyopathies with reduced left ventricular ejection fraction (LVEF) has not been evaluated yet...
  16. doi request reprint Assessment of global longitudinal strain using standardized myocardial deformation imaging: a modality independent software approach
    Johannes H Riffel
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Clin Res Cardiol 104:591-602. 2015
    ....
  17. pmc CXCL4 Plasma Levels Are Not Associated with the Extent of Coronary Artery Disease or with Coronary Plaque Morphology
    Christian Erbel
    Department of Cardiology, University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany DZHK German Centre for Cardiovascular Research, partner site Heidelberg, Germany
    PLoS ONE 10:e0141693. 2015
    ..Specifically, we sought to determine whether CXCL4 levels are correlated with specific features of coronary artery disease including (1) plaque volume, (2) calcium score, (3) degree of stenosis, or (4) vascular remodeling...
  18. doi request reprint Quantitative analysis of left ventricular dyssynchrony using cardiac computed tomography versus three-dimensional echocardiography
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Eur Radiol 22:1303-9. 2012
    ....
  19. pmc Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis
    Ziya Kaya
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Circulation 118:2063-72. 2008
    ..Recently, we showed that an autoimmune response to cardiac troponin I (cTnI) induces severe inflammation and subsequent fibrosis in the myocardium. This autoimmune disorder predisposes to heart failure and cardiac death in mice...
  20. ncbi request reprint Evidence of left ventricular contractile asynchrony by echocardiographic phase imaging in patients with type 2 diabetes mellitus and without clinically evident heart disease
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am J Cardiol 98:1525-30. 2006
    ..05) and showed higher intraobserver variability (5.6% vs 3.2%, p <0.05). In conclusion, this is the first study showing increased left ventricular asynchrony in patients with DM and no clinical evidence of heart disease...
  21. doi request reprint Anterior Aortic Plane Systolic Excursion: A Novel Indicator of Transplant-Free Survival in Systemic Light-Chain Amyloidosis
    Marco M Ochs
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany Electronic address
    J Am Soc Echocardiogr 29:1188-1196. 2016
    ..Anterior aortic plane systolic excursion (AAPSE) was evaluated in the present pilot study as a novel echocardiographic indicator of transplant-free survival in patients with systemic light-chain amyloidosis...
  22. pmc Cardiac Effects of Attenuating Gsα - Dependent Signaling
    Marcus R Streit
    Department of Cardiology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    PLoS ONE 11:e0146988. 2016
    ..Gsα is essential for β-adrenergic signal transduction. In order to reduce side-effects of beta-adrenergic inhibition diminishing β-adrenergic signalling in the heart at the level of Gsα is a promising option...
  23. doi request reprint Extracellular remodeling in patients with wild-type amyloidosis consuming epigallocatechin-3-gallate: preliminary results of T1 mapping by cardiac magnetic resonance imaging in a small single center study
    Fabian Aus dem Siepen
    Department of Cardiology, Angiology, Pneumology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Clin Res Cardiol 104:640-7. 2015
    ..It remained unclear, whether reduction of LV myocardial mass reflects decrease of amyloid load or progressive atrophy of cardiomyocytes...
  24. doi request reprint Left ventricular diastolic function in type 2 diabetes mellitus is associated with myocardial triglyceride content but not with impaired myocardial perfusion reserve
    Grigorios Korosoglou
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    J Magn Reson Imaging 35:804-11. 2012
    ....
  25. pmc DYRK2 negatively regulates cardiomyocyte growth by mediating repressor function of GSK-3β on eIF2Bε
    Celine S Weiss
    Internal Medicine III, University Hospital Heidelberg and DZHK German Center for Cardiovascular Research, Heidelberg, Germany
    PLoS ONE 8:e70848. 2013
    ..A central regulator of translation initiation is Eukaryotic initiation factor 2B (eIF2B). Here we assessed the hypothesis that regulation of protein synthesis via eIF2Bε is essential to cardiac hypertrophic response in vivo...
  26. doi request reprint Chronic Akt blockade aggravates pathological hypertrophy and inhibits physiological hypertrophy
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    Am J Physiol Heart Circ Physiol 302:H420-30. 2012
    ..In conclusion, chronic Akt blockade with deguelin aggravates adverse myocardial remodeling and antagonizes physiological hypertrophy...
  27. pmc Fast assessment of long axis strain with standard cardiovascular magnetic resonance: a validation study of a novel parameter with reference values
    Johannes H Riffel
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, INF 410, 69120, Heidelberg, Germany
    J Cardiovasc Magn Reson 17:69. 2015
    ..The aim of this study was to develop a fast assessable parameter for the measurement of long axis strain (LAS) with CMR...
  28. pmc Age- and gender-related normal left ventricular deformation assessed by cardiovascular magnetic resonance feature tracking
    Florian André
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, 69120, Germany
    J Cardiovasc Magn Reson 17:25. 2015
    ..The aim of the study was to provide reference values for myocardial deformation derived from the CMR feature tracking imaging (FTI) algorithm in a reference population of healthy volunteers...
  29. doi request reprint Combined Assessment of High-Sensitivity Troponin T and Noninvasive Coronary Plaque Composition for the Prediction of Cardiac Outcomes
    Gitsios Gitsioudis
    From the Department of Cardiology G G, A s, E N, S J B, N H, E G, H A K, G K, Institute of Psychology A V, and Department of Diagnostic and Interventional Radiology W H, H U K, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, 69120, Germany and MTA SE Lendület Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, Budapest, Hungary E N, P M H
    Radiology 276:73-81. 2015
    ....
  30. doi request reprint Aldosterone augments Na+-induced reduction of cardiac norepinephrine reuptake
    Michael M Kreusser
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany German Centre for Cardiovascular Research, Heidelberg Mannheim, Germany
    Am J Physiol Heart Circ Physiol 307:H1169-77. 2014
    ..We conclude that exogenous or endogenous AL elevations alone do not reduce cardiac NE reuptake, but AL serves as an additional factor that negatively regulates cardiac NE reuptake in concert with HS intake. ..
  31. pmc When do we really need coronary calcium scoring prior to contrast-enhanced coronary computed tomography angiography? Analysis by age, gender and coronary risk factors
    Gitsios Gitsioudis
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    PLoS ONE 9:e92396. 2014
    ..To investigate the value of coronary calcium scoring (CCS) as a filter scan prior to coronary computed tomography angiography (CCTA)...
  32. doi request reprint Reduction of radiation exposure and improvement of image quality with BMI-adapted prospective cardiac computed tomography and iterative reconstruction
    Waldemar Hosch
    University of Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg, Germany
    Eur J Radiol 81:3568-76. 2012
    ....
  33. doi request reprint Right ventricular long axis strain-validation of a novel parameter in non-ischemic dilated cardiomyopathy using standard cardiac magnetic resonance imaging
    Nisha Arenja
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Eur J Radiol 85:1322-8. 2016
    ..The purpose of this study was the evaluation of its diagnostic performance in non-ischemic dilated cardiomyopathy (NIDCM) and the determination of reference values in controls...
  34. doi request reprint A comprehensive analysis of cardiac valve plane displacement in healthy adults: age-stratified normal values by cardiac magnetic resonance
    Marco M Ochs
    Department of Cardiology, University of Heidelberg, INF 410, 69120, Heidelberg, Germany
    Int J Cardiovasc Imaging . 2017
    ..Age-stratified normal values of regional CVPD are provided. AAPSE revealed the most pronounced age-related decrease and provided favorable reproducibility compared to other regions of cardiac valve plane...
  35. doi request reprint Incremental value of cardiac deformation analysis in acute myocarditis: a cardiovascular magnetic resonance imaging study
    Florian André
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Int J Cardiovasc Imaging 32:1093-101. 2016
    ..Cardiac strains measured by CMR-FTI are significantly impaired in patients with acute myocarditis even in those with pEF. Therefore, strain assessment may improve the diagnostic accuracy of CMR for myocarditis. ..
  36. pmc Epicardial Adipose Tissue Is Associated with Plaque Burden and Composition and Provides Incremental Value for the Prediction of Cardiac Outcome. A Clinical Cardiac Computed Tomography Angiography Study
    Gitsios Gitsioudis
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    PLoS ONE 11:e0155120. 2016
    ..We sought to investigate the association of epicardial adipose tissue (eCAT) volume with plaque burden, circulating biomarkers and cardiac outcomes in patients with intermediate risk for coronary artery disease (CAD)...
  37. doi request reprint Myocardial Perfusion Reserve and Strain-Encoded CMR for Evaluation of Cardiac Allograft Microvasculopathy
    Christian Erbel
    Department of Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    JACC Cardiovasc Imaging 9:255-66. 2016
    ..This study sought to evaluate myocardial perfusion reserve index (MPRI) and diastolic strain rate, both assessed by cardiac magnetic resonance (CMR) as a noninvasive tool for the detection of microvasculopathy...
  38. pmc Green tea extract as a treatment for patients with wild-type transthyretin amyloidosis: an observational study
    Fabian Aus dem Siepen
    Department of Cardiology, Angiology, and Respiratory Medicine, University Hospital Heidelberg, Heidelberg, Germany
    Drug Des Devel Ther 9:6319-25. 2015
    ..We sought to investigate changes of cardiac function and morphology in patients with wtATTR-CM after consumption of green tea extract (GTE)...
  39. doi request reprint Assessment of myocardial deformation with cardiac magnetic resonance strain imaging improves risk stratification in patients with dilated cardiomyopathy
    Sebastian J Buss
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, INF 410, Heidelberg 69120, Germany
    Eur Heart J Cardiovasc Imaging 16:307-15. 2015
    ....
  40. doi request reprint Prediction of functional recovery by cardiac magnetic resonance feature tracking imaging in first time ST-elevation myocardial infarction. Comparison to infarct size and transmurality by late gadolinium enhancement
    Sebastian J Buss
    Department of Cardiology, University of Heidelberg, INF 410, 69120 Heidelberg, Germany
    Int J Cardiol 183:162-70. 2015
    ....
  41. doi request reprint Assessment of left ventricular volumes with echocardiography and cardiac magnetic resonance imaging: real-life evaluation of standard versus new semiautomatic methods
    Matthias Aurich
    Department of Internal Medicine III, Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany Electronic address
    J Am Soc Echocardiogr 27:1017-24. 2014
    ..Thus, the aim of this study was to evaluate faster new semiautomatic echocardiographic methods that could represent a feasible alternative for the assessment of LV volumes and ejection fraction (EF) in clinical practice...
  42. doi request reprint Dobutamine stress cardiac magnetic resonance versus echocardiography for the assessment of outcome in patients with suspected or known coronary artery disease. Are the two imaging modalities comparable?
    Eleni Bikiri
    University of Heidelberg, Department of Cardiology, Heidelberg, Germany
    Int J Cardiol 171:153-60. 2014
    ..To compare the value of Dobutamine stress echocardiography (DSE) with that provided by Dobutamine Cardiac Magnetic Resonance (DCMR) for the non-invasive risk stratification of patients with suspected or known coronary artery disease (CAD)...
  43. doi request reprint T1 mapping in dilated cardiomyopathy with cardiac magnetic resonance: quantification of diffuse myocardial fibrosis and comparison with endomyocardial biopsy
    Fabian Aus dem Siepen
    Department of Cardiology, Angiology and Pneumology, University Hospital Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany
    Eur Heart J Cardiovasc Imaging 16:210-6. 2015
    ....
  44. doi request reprint Reference values for left and right ventricular trabeculation and non-compacted myocardium
    Florian André
    University of Heidelberg, Department of Cardiology, Angiology and Pneumology, Im Neuenheimer Feld 410, Heidelberg 69120, Germany Electronic address
    Int J Cardiol 185:240-7. 2015
    ..Since the differentiation between physiological and pathological trabeculation is challenging, we assessed its distribution in a reference population of selected healthy volunteers...
  45. doi request reprint Strain-encoded cardiac magnetic resonance during high-dose dobutamine stress testing for the estimation of cardiac outcomes: comparison to clinical parameters and conventional wall motion readings
    Grigorios Korosoglou
    Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany
    J Am Coll Cardiol 58:1140-9. 2011
    ....
  46. ncbi request reprint Electrophysiological findings in Fabry cardiomyopathy: mapping the maze of risk stratification
    Jin Li
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Acta Cardiol 67:481-5. 2012
    ..Review of the literature indicates limited knowledge on the electrophysiology of Fabry cardiomyopathy and highlights the need for optimized risk stratification strategies...
  47. doi request reprint Effects of the main green tea polyphenol epigallocatechin-3-gallate on cardiac involvement in patients with AL amyloidosis
    Derliz Mereles
    Department of Internal Medicine III, University of Heidelberg, Germany
    Clin Res Cardiol 99:483-90. 2010
    ..This is a report of the cardiac effects of green tea consumption in these patients...
  48. ncbi request reprint Injection of nerve growth factor into stellate ganglia improves norepinephrine reuptake into failing hearts
    Michael M Kreusser
    Department of Cardiology, University of Heidelberg, Germany
    Hypertension 47:209-15. 2006
    ..In conclusion, nerve growth factor attenuates local cardiac sympathetic overdrive of hypertrophic hearts by improving cardiac norepinephrine reuptake and might represent a novel therapeutic principle in the treatment of heart failure...
  49. pmc Quantification of myocardial deformation in children by cardiovascular magnetic resonance feature tracking: determination of reference values for left ventricular strain and strain rate
    Florian André
    Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany
    J Cardiovasc Magn Reson 19:8. 2016
    ..Thus, the aim of this study was to provide reference values for cardiac strain and strain rate in children and adolescents derived from CMR feature tracking (FT) measurements...
  50. doi request reprint The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel
    Patrick A Schweizer
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany DZHK German Centre for Cardiovascular Research, partner site Heidelberg Mannheim, University of Heidelberg, Heidelberg, Germany Electronic address
    J Am Coll Cardiol 64:757-67. 2014
    ..There is growing evidence that ion channel dysfunction also contributes to myocardial disorders, but genetic overlap has not been reported for sinus node dysfunction (SND) and noncompaction cardiomyopathy (NCCM)...
  51. pmc Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling
    Lorenz H Lehmann
    Research Unit Cardiac Epigenetics, Department of Cardiology, University of Heidelberg, D 69120 Heidelberg, Germany DZHK German Centre for Cardiovascular Research, partner site Heidelberg Mannheim, D 69120 Heidelberg, Germany
    Proc Natl Acad Sci U S A 111:13499-504. 2014
    ..Taken together, this may indicate that patients with β blocker intolerance or disturbed sympathetic nerve function could be evaluated for a potential benefit from ETAi. ..
  52. ncbi request reprint Cardiac troponin I but not cardiac troponin T induces severe autoimmune inflammation in the myocardium
    Stefan Göser
    Department of Internal Medicine III, University of Heidelberg, 69120 Heidelberg, Germany
    Circulation 114:1693-702. 2006
    ..Thus, the cardiac troponins are paramount for disease classification and risk stratification. However, little is known about the long-term effects of the released troponins on cardiac function...
  53. doi request reprint Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease
    Christian A Gleissner
    Department of Cardiology, University Hospital, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Clin Res Cardiol 104:13-22. 2015
    ..These findings may represent the link between in vitro studies demonstrating atheroprotective effects of anti-PC IgM and clinical data demonstrating that low anti-PC IgM levels are associated with adverse outcome in CAD patients...