Wolfgang Bäumler

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. ncbi request reprint Phototherapy of psoriasis: comparative experience of different phototherapeutic approaches
    S Karrer
    Department of Dermatology, University of Regensburg, Germany
    Dermatology 202:108-15. 2001
  2. doi request reprint Tattoo inks contain polycyclic aromatic hydrocarbons that additionally generate deleterious singlet oxygen
    Johannes Regensburger
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Exp Dermatol 19:e275-81. 2010
  3. doi request reprint Exposure of vitamins to UVB and UVA radiation generates singlet oxygen
    Alena Knak
    Department of Dermatology, University of Regensburg, Germany
    Photochem Photobiol Sci 13:820-9. 2014
  4. doi request reprint Intravenous injection of indocyanine green to enhance laser-assisted coagulation of blood vessels in skin - an animal study
    W Baumler
    Departments of Dermatology, Universities of Regensburg, Regensburg, Germany
    J Eur Acad Dermatol Venereol 27:e206-11. 2013
  5. doi request reprint UVA and endogenous photosensitizers--the detection of singlet oxygen by its luminescence
    Wolfgang Bäumler
    Department of Dermatology, University of Regensburg, 93042, Regensburg, Germany
    Photochem Photobiol Sci 11:107-17. 2012
  6. ncbi request reprint Q-switch laser and tattoo pigments: first results of the chemical and photophysical analysis of 41 compounds
    W Baumler
    Department of Dermatology University of Regensburg, Germany
    Lasers Surg Med 26:13-21. 2000
  7. ncbi request reprint The effects of intense pulsed light (IPL) on blood vessels investigated by mathematical modeling
    Wolfgang Bäumler
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Lasers Surg Med 39:132-9. 2007
  8. ncbi request reprint [Laser therapy for tattoos]
    W Baumler
    Poliklinik für Dermatologie, Universitat Regensburg
    MMW Fortschr Med 148:37, 39-40. 2006
  9. ncbi request reprint The effect of different spot sizes on the efficacy of hair removal using a long-pulsed diode laser
    Wolfgang Bäumler
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Dermatol Surg 28:118-21. 2002
  10. ncbi request reprint Optimal parameters for the treatment of leg veins using Nd:YAG lasers at 1064 nm
    W Baumler
    Department of Dermatology, University of Regensburg, 93042 Regensburg, Germany Vascular Anomalies Centre, Arkansas Children s Hospital, Little Rock, AR 72202, USA
    Br J Dermatol 155:364-71. 2006

Detail Information

Publications145 found, 100 shown here

  1. ncbi request reprint Phototherapy of psoriasis: comparative experience of different phototherapeutic approaches
    S Karrer
    Department of Dermatology, University of Regensburg, Germany
    Dermatology 202:108-15. 2001
    ....
  2. doi request reprint Tattoo inks contain polycyclic aromatic hydrocarbons that additionally generate deleterious singlet oxygen
    Johannes Regensburger
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Exp Dermatol 19:e275-81. 2010
    ..Most of these PAHs are carcinogenic and may additionally generate deleterious singlet oxygen inside the dermis when skin is exposed to UVA (e.g. solar radiation)...
  3. doi request reprint Exposure of vitamins to UVB and UVA radiation generates singlet oxygen
    Alena Knak
    Department of Dermatology, University of Regensburg, Germany
    Photochem Photobiol Sci 13:820-9. 2014
    ..These results should be of particular importance for parallel irradiation with UVA and UVB in vivo, e.g. when exposing the skin to solar radiation. ..
  4. doi request reprint Intravenous injection of indocyanine green to enhance laser-assisted coagulation of blood vessels in skin - an animal study
    W Baumler
    Departments of Dermatology, Universities of Regensburg, Regensburg, Germany
    J Eur Acad Dermatol Venereol 27:e206-11. 2013
    ..We propose to improve blood vessel coagulation by intravenous introduction of an exogenous chromophore (indocyanine green, ICG) that effectively converts near-infrared (NIR) laser light into heat...
  5. doi request reprint UVA and endogenous photosensitizers--the detection of singlet oxygen by its luminescence
    Wolfgang Bäumler
    Department of Dermatology, University of Regensburg, 93042, Regensburg, Germany
    Photochem Photobiol Sci 11:107-17. 2012
    ..This article describes the endogenous photosensitizers, their ability to generate (1)O(2) under UVA irradiation, and the detection technology to visualize the action of (1)O(2)...
  6. ncbi request reprint Q-switch laser and tattoo pigments: first results of the chemical and photophysical analysis of 41 compounds
    W Baumler
    Department of Dermatology University of Regensburg, Germany
    Lasers Surg Med 26:13-21. 2000
    ....
  7. ncbi request reprint The effects of intense pulsed light (IPL) on blood vessels investigated by mathematical modeling
    Wolfgang Bäumler
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Lasers Surg Med 39:132-9. 2007
    ..However, the broadband emission of IPL hampers the clinical evaluation of optimal light parameters. We describe a mathematical model in order to visualize the thermal effects of IPL on skin vessels, which was not available, so far...
  8. ncbi request reprint [Laser therapy for tattoos]
    W Baumler
    Poliklinik für Dermatologie, Universitat Regensburg
    MMW Fortschr Med 148:37, 39-40. 2006
    ..The success of the laser treatment essentially depends on the pigments used in the tattoo and on how deeply the pigments are embedded in the skin. The laser treatment is slightly painful and has a low rate of permanent side effects...
  9. ncbi request reprint The effect of different spot sizes on the efficacy of hair removal using a long-pulsed diode laser
    Wolfgang Bäumler
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Dermatol Surg 28:118-21. 2002
    ..In the last years several lasers have proven their efficacy for hair removal. However, little is known about the efficacy of varying the spot size with those lasers...
  10. ncbi request reprint Optimal parameters for the treatment of leg veins using Nd:YAG lasers at 1064 nm
    W Baumler
    Department of Dermatology, University of Regensburg, 93042 Regensburg, Germany Vascular Anomalies Centre, Arkansas Children s Hospital, Little Rock, AR 72202, USA
    Br J Dermatol 155:364-71. 2006
    ..However, it is still unclear how laser parameters such as wavelength, fluence and pulse duration influence vessel destruction in leg veins...
  11. ncbi request reprint Establishment of an extraction method for the recovery of tattoo pigments from human skin using HPLC diode array detector technology
    Eva Engel
    Department of Organic Chemistry, University of Regensburg, Germany
    Anal Chem 78:6440-7. 2006
    ..The decomposition products were extracted from aqueous suspension or skin showing a recovery of up to 100%, except for the very volatile 1,4-DCB...
  12. doi request reprint Light-induced decomposition of indocyanine green
    Eva Engel
    Departments of Organic Chemistry, University of Regensburg, Regensburg, Germany
    Invest Ophthalmol Vis Sci 49:1777-83. 2008
    ..To investigate the light-induced decomposition of indocyanine green (ICG) and to test the cytotoxicity of light-induced ICG decomposition products...
  13. doi request reprint A helpful technology--the luminescence detection of singlet oxygen to investigate photodynamic inactivation of bacteria (PDIB)
    Johannes Regensburger
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    J Biophotonics 3:319-27. 2010
    ..The decay times should provide an indication of localization of singlet oxygen and hence of the photosensitizer even in small bacteria...
  14. doi request reprint Modern tattoos cause high concentrations of hazardous pigments in skin
    Eva Engel
    Department of Organic Chemistry, University of Regensburg, 93042 Regensburg, Germany
    Contact Dermatitis 58:228-33. 2008
    ..Modern tattoo colourants frequently consist of azo pigments that not only contain multiple impurities but also are originally produced for car paint and the dyeing of consumer goods...
  15. ncbi request reprint Tattoo pigments are cleaved by laser light-the chemical analysis in vitro provide evidence for hazardous compounds
    Rudolf Vasold
    Department of Organic Chemistry, University of Regensburg, 93042 Regensburg, Germany
    Photochem Photobiol 80:185-90. 2004
    ..Because of a high number of patients undergoing laser treatment of tattoos and based on the results of our findings in vitro, it is an important goal to perform a risk assessment in humans regarding laser-induced decomposition products...
  16. ncbi request reprint Time-resolved investigations of singlet oxygen luminescence in water, in phosphatidylcholine, and in aqueous suspensions of phosphatidylcholine or HT29 cells
    Jürgen Baier
    Department of Dermatology, University of Regensburg, Germany, and Institute of Experimental and Applied Physics, University of Regensburg, Germany
    J Phys Chem B 109:3041-6. 2005
    ..In contrast to experiments with Photofrin, the decay time in aqueous suspension of HT29 cells was 6 +/- 2 micros when using ATMPn...
  17. doi request reprint Dirty hands: photodynamic killing of human pathogens like EHEC, MRSA and Candida within seconds
    Anja Eichner
    Department of Dermatology, Regensburg University Hospital, 93053 Regensburg, Germany
    Photochem Photobiol Sci 12:135-47. 2013
    ..Being fast and effective, antimicrobial photodynamic applications might become acceptable as a tool for hand hygiene procedures and also in other skin areas...
  18. doi request reprint Fatty acids and vitamins generate singlet oxygen under UVB irradiation
    Johannes Regensburger
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Exp Dermatol 21:135-9. 2012
    ..An increase in singlet oxygen generation may initiate a vicious cycle that has the potential to amplify UVB- or UVA-mediated effects in skin cells...
  19. doi request reprint Luminescence spectroscopy of singlet oxygen enables monitoring of oxygen consumption in biological systems consisting of fatty acids
    Anita Gollmer
    Department of Dermatology, University Hospital Regensburg, 93042 Regensburg, Germany
    Phys Chem Chem Phys 15:11386-93. 2013
    ..In conclusion, luminescence detection might be a helpful tool to monitor precisely and promptly changes in oxygen concentration in a complex environment...
  20. ncbi request reprint Photothermolysis of blood vessels using indocyanine green and pulsed diode laser irradiation in the dorsal skinfold chamber model
    Philipp Babilas
    Department of Dermatology, Regensburg University Medical Center, 93042 Regensburg, Germany
    Lasers Surg Med 39:341-52. 2007
    ..For the treatment of vascular lesions, the use of laser light absorbed by the endogenous chromophore hemoglobin may still be improved...
  21. pmc Singlet oxygen generation by UVA light exposure of endogenous photosensitizers
    Jürgen Baier
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Biophys J 91:1452-9. 2006
    ..With decreasing oxygen concentration, the quantum yield of singlet oxygen generation decreased, which must be considered when assessing the role of singlet oxygen at low oxygen concentrations (inside tissue)...
  22. doi request reprint Fungicidal photodynamic effect of a twofold positively charged porphyrin against Candida albicans planktonic cells and biofilms
    Fernanda Pereira Gonzales
    Department of Dermatology, University Hospital Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Future Microbiol 8:785-97. 2013
    ..Candida albicans biofilms frequently cause such infections that can even evolve to deep-seated mycoses...
  23. pmc The role of singlet oxygen and oxygen concentration in photodynamic inactivation of bacteria
    Tim Maisch
    Department of Dermatology, University of Regensburg, 93042 Regensburg, Germany
    Proc Natl Acad Sci U S A 104:7223-8. 2007
    ....
  24. doi request reprint Fast and effective: intense pulse light photodynamic inactivation of bacteria
    Tim Maisch
    Department of Dermatology, Regensburg University Hospital, Franz Josef Strauss Allee 11, 93053, Regensburg, Germany
    J Ind Microbiol Biotechnol 39:1013-21. 2012
    ....
  25. doi request reprint Indocyanine green-augmented diode laser therapy of telangiectatic leg veins: a randomized controlled proof-of-concept trial
    Annette Klein
    Department of Dermatology, University Hospital Regensburg, 93042 Regensburg, Germany
    Lasers Surg Med 44:369-76. 2012
    ..Besides sclerotherapy, various laser devices are common treatment options. However, complete clearance rates can only be achieved in a small number of patients...
  26. doi request reprint Tattooing of skin results in transportation and light-induced decomposition of tattoo pigments--a first quantification in vivo using a mouse model
    Eva Engel
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Exp Dermatol 19:54-60. 2010
    ..This study is the first quantitative estimate of the amount of tattoo pigments transported from the skin into the body or decomposed by solar or laser radiation...
  27. ncbi request reprint Safety testing of indocyanine green in an ex vivo porcine retina model
    Parykshit Saikia
    Department of Ophthalmology, University of Regensburg, Franz Josef Strauss Allee 11, D 93042 Regensburg, Germany
    Invest Ophthalmol Vis Sci 47:4998-5003. 2006
    ..To assess retinal toxicity of indocyanine green (ICG) in a porcine ex vivo perfusion organ culture model, and to measure intraretinal penetration of ICG applied to the retinal surface...
  28. ncbi request reprint Selective photothermolysis of blood vessels following flashlamp-pumped pulsed dye laser irradiation: in vivo results and mathematical modelling are in agreement
    Philipp Babilas
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    J Invest Dermatol 125:343-52. 2005
    ..Because of incomplete photocoagulation of smaller blood vessels (diameter 2-16 microm) a complete bleaching of PWS seems to be unlikely...
  29. doi request reprint Intense pulse light and 5-ALA PDT: phototoxic effects in vitro depend on the spectral overlap with protoporphyrine IX but do not match cut-off filter notations
    Tim Maisch
    Department of Dermatology, Regensburg University Hospital, 93053 Regensburg, Germany
    Lasers Surg Med 43:176-82. 2011
    ..Five different IPLs were chosen to evaluate their efficacy for PDT in vitro and the possibility for developing a standard protocol for PDT...
  30. ncbi request reprint Time dependence of singlet oxygen luminescence provides an indication of oxygen concentration during oxygen consumption
    Jürgen Baier
    University of Regensburg, Department of Dermatology, 93042 Regensburg, Germany
    J Biomed Opt 12:064008. 2007
    ..Thus, local oxygen consumption could be monitored during photodynamic action by evaluating the course of singlet oxygen luminescence...
  31. doi request reprint A randomized controlled trial to optimize indocyanine green-augmented diode laser therapy of capillary malformations
    Annette Klein
    Department of Dermatology, University Hospital Regensburg, Regensburg, 93042, Germany
    Lasers Surg Med 45:216-24. 2013
    ..However, an increase of the ICG-concentration or the use of an intense pulsed light (IPL) device as light source may further optimize treatment outcomes in CM...
  32. doi request reprint Ion-induced stacking of photosensitizer molecules can remarkably affect the luminescence detection of singlet oxygen in Candida albicans cells
    Ariane Felgenträger
    Regensburg University Hospital, Department of Dermatology, 93053 Regensburg, Germany
    J Biomed Opt 18:045002. 2013
    ..These effects should be considered for any other photosensitizer used in photodynamic processes...
  33. ncbi request reprint Mathematical modeling of selective photothermolysis to aid the treatment of vascular malformations and hemangioma with pulsed dye laser
    Gal Shafirstein
    Department of Otolaryngology, Vascular Anomalies Center, Arkansas Children s Hospital and University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Lasers Med Sci 22:111-8. 2007
    ..The table cannot replace a clinician's experience with respect to which and how parameters should be changed, but provides a defined window of parameters that should be tried to improve clinical response...
  34. ncbi request reprint Azo pigments and a basal cell carcinoma at the thumb
    Eva Engel
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Dermatology 216:76-80. 2008
    ..As a result of the frequent skin contact to this azo pigment, this hazard compound might have induced the basal cell carcinoma in our patient...
  35. doi request reprint Black tattoo inks are a source of problematic substances such as dibutyl phthalate
    Karin Lehner
    Department of Dermatology, University of Regensburg, 93042 Regensburg, Germany
    Contact Dermatitis 65:231-8. 2011
    ..Most tattoos consist of black inks, which are predominantly composed of soot products (carbon black with polycyclic aromatic hydrocarbons)...
  36. pmc Fast and effective photodynamic inactivation of multiresistant bacteria by cationic riboflavin derivatives
    Tim Maisch
    Department of Dermatology, University Hospital Regensburg, Regensburg, Germany
    PLoS ONE 9:e111792. 2014
    ..Further work will include these new photosensitizers for topical application to decolonize bacteria from skin and mucosa. ..
  37. doi request reprint Fast and effective inactivation of Bacillus atrophaeus endospores using light-activated derivatives of vitamin B2
    Anja Eichner
    Department of Dermatology, Regensburg University Hospital, 93053 Regensburg, Germany
    Photochem Photobiol Sci 14:387-96. 2015
    ..The results of this study show evidence that endospores can be fastly and effectively inactivated with new generations of flavin photosensitizers that may be useful for industrial or medical applications in the future. ..
  38. doi request reprint Health risks of tattoo colors
    Rudolf Vasold
    University of Regensburg, Universitätsstr 31, 93053, Regensburg, Germany
    Anal Bioanal Chem 391:9-13. 2008
  39. ncbi request reprint Direct detection of singlet oxygen generated by UVA irradiation in human cells and skin
    Jürgen Baier
    Department of Dermatology, Regensburg University Medical Center, Regensburg, Germany
    J Invest Dermatol 127:1498-506. 2007
    ..Additionally, the monochromatic UVA irradiation at 355 nm leads to upregulation of the key cytokine IL-12. This affects the balance of UV radiation on the immune system, which is comparable to effects of broadband UVA irradiation...
  40. doi request reprint Optical detection of singlet oxygen produced by fatty acids and phospholipids under ultraviolet A irradiation
    Jürgen Baier
    University of Regensburg, Department of Dermatology, 93042 Regensburg, Germany
    J Biomed Opt 13:044029. 2008
    ..This leads to an enhancement of UVA-induced damage of fatty acids and lipids, which must enhance the oxidative damages in cells...
  41. doi request reprint Photodynamic inactivation of multi-resistant bacteria (PIB) - a new approach to treat superficial infections in the 21st century
    Tim Maisch
    Department of Dermatology, University of Regensburg, Germany
    J Dtsch Dermatol Ges 9:360-6. 2011
    ..In this review the physical-chemical and biological basics of photo-dynamic inactivation of bacteria (PIB) will be discussed as well as the possible dermatological indications...
  42. ncbi request reprint Identification of differentially expressed genes in models of melanoma progression by cDNA array analysis: SPARC, MIF and a novel cathepsin protease characterize aggressive phenotypes
    G Rumpler
    Department of Dermatology, University of Regensburg, Germany
    Exp Dermatol 12:761-71. 2003
    ....
  43. ncbi request reprint Exacerbation of pityriasis rubra pilaris under efalizumab therapy
    A Klein
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Dermatology 215:72-5. 2007
    ..Efalizumab has been approved for the treatment of moderate to severe psoriasis, but there are no reports in the literature on the use of efalizumab for pityriasis rubra pilaris...
  44. pmc Black tattoos entail substantial uptake of genotoxicpolycyclic aromatic hydrocarbons (PAH) in human skin and regional lymph nodes
    Karin Lehner
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    PLoS ONE 9:e92787. 2014
    ..Thus, beside inhalation and ingestion, tattooing has proven to be an additional, direct and effective route of PAH uptake into the human body...
  45. doi request reprint Using 5-aminolevulinic acid and pulsed dye laser for photodynamic treatment of oral leukoplakia
    Gal Shafirstein
    Department of Otolaryngology, Jackson T Stephens Spine Center, University of Arkansas for Medical Sciences, 501 Jack Stephens Drive, Little Rock, AR 72205, USA
    Arch Otolaryngol Head Neck Surg 137:1117-23. 2011
    ..To determine the safety and efficacy of photodynamic therapy in the treatment of oral leukoplakia with 5-aminolevulinic acid and pulsed dye laser...
  46. doi request reprint Laser thermal therapy of benign skin tumours: review and update
    Annette Klein
    Department of Dermatology, University Hospital Regensburg, Germany
    Int J Hyperthermia 27:762-70. 2011
    ..Recently, fractional laser devices or combination of laser therapy with photodynamic therapy has gained attention in this field. However, there is a lack of randomised, controlled trials for laser treatment of benign skin tumours...
  47. ncbi request reprint Theoretical and experimental analysis of the luminescence signal of singlet oxygen for different photosensitizers
    Jürgen Baier
    Universitat Regensburg, Dermatologie, 93042 Regensburg, Germany
    J Photochem Photobiol B 87:163-73. 2007
    ..Since cells show low oxygen concentrations, this must have an impact when looking at singlet oxygen detection in vitro or in vivo...
  48. ncbi request reprint Disappointing results and low tolerability of photodynamic therapy with topical 5-aminolaevulinic acid in psoriasis. A randomized, double-blind phase I/II study
    V Schleyer
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    J Eur Acad Dermatol Venereol 20:823-8. 2006
    ..However, there is still a lack of well-documented trials...
  49. ncbi request reprint Teledermatoscopy in daily routine--results of the first 100 cases
    B Coras
    Department of Dermatology, University of Regensburg, Germany
    Curr Probl Dermatol 32:207-12. 2003
  50. doi request reprint A novel set of symmetric methylene blue derivatives exhibits effective bacteria photokilling - a structure-response study
    Anita Gollmer
    Department of Dermatology, University Medical Center Regensburg, Germany
    Photochem Photobiol Sci 14:335-51. 2015
    ..99%)) and no antimicrobial effect on Staphylococcus aureus. This might allow the development of a new generation of photosensitizers with higher antimicrobial efficacy and selectivity for future applications. ..
  51. doi request reprint Improving photodynamic inactivation of bacteria in dentistry: highly effective and fast killing of oral key pathogens with novel tooth-colored type-II photosensitizers
    Andreas Späth
    Department of Organic Chemistry, University of Regensburg, Regensburg, Germany
    J Med Chem 57:5157-68. 2014
    ..9999%) of bacteria killing is reached in less than 1 min (light dose 50 J/cm(2)) after one single treatment. The pyridinium substituent as positively charged moiety is especially advantageous for antimicrobial action...
  52. doi request reprint An Internet-based survey on characteristics of laser tattoo removal and associated side effects
    Annette Klein
    Department of Dermatology, University Hospital Regensburg, Franz Josef Strauss Allee 11, 93042, Regensburg, Germany
    Lasers Med Sci 29:729-38. 2014
    ..Laser treatment should be performed by appropriately trained personnel only...
  53. doi request reprint Permanent make-up colorants may cause severe skin reactions
    Sabrina M Wenzel
    Department of Dermatology, Regensburg University Medical Centre, Regensburg 93053, Germany
    Contact Dermatitis 63:223-7. 2010
    ..However, most colorants are manufactured for non-medical purposes, without any established history of safe use in humans...
  54. doi request reprint [Skin and teeth]
    J Heinlin
    Klinik und Poliklinik fur Dermatologie, Universitätsklinik Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg
    Hautarzt 60:583-97; quiz 598. 2009
    ..The understanding and appreciation of dental abnormalities guides dermatologists in the diagnosis and identification of syndromes as well as in finding an optimal therapy...
  55. ncbi request reprint Laser surgical planning with magnetic resonance imaging-based 3-dimensional reconstructions for intralesional Nd:YAG laser therapy of a venous malformation of the neck
    A Glaessl
    Department of Dermatology, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Arch Dermatol 137:1331-5. 2001
    ..The therapeutic problem is to localize the venous malformation exactly before treatment on sectional 2-dimensional images...
  56. doi request reprint [Skin and eyes]
    E Kohl
    Klinik und Poliklinik fur Dermatologie, Universitatsklinikum Regensburg, Franz Josef Strauss Allee 11, 93053, Regensburg
    Hautarzt 60:63-74; quiz 75. 2009
    ..Various immunobullous disorders involve the conjunctiva with varying severity. Side effects of dermatologic treatments with glucocorticoids, antimalarials, psoralens, retinoids, or tetracyclines may involve the eye...
  57. doi request reprint FGFR3 and PIK3CA mutations are involved in the molecular pathogenesis of solar lentigo
    C Hafner
    Department of Dermatology, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Br J Dermatol 160:546-51. 2009
    ..It has been proposed that SL may subsequently evolve into adenoid seborrhoeic keratosis (SK). However, little is known about the genetic basis of SL. In human SK, FGFR3 and PIK3CA mutations have recently been identified...
  58. doi request reprint [Linear IgA disease with ocular involvement associated with ulcerative colitis]
    A Klein
    Klinik und Poliklinik fur Dermatologie, Klinikum der Universitat Regensburg, Regensburg, Deutschland
    Hautarzt 61:55-7. 2010
    ..After the diagnosis of LAD was established, dapsone was added. With this therapy, the ocular inflammation decreased significantly and the methylprednisolone dose could be successfully tapered slowly without reappearance of vesicles...
  59. ncbi request reprint Role of lasers and photodynamic therapy in the treatment of cutaneous malignancy
    S Karrer
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Am J Clin Dermatol 2:229-37. 2001
    ..However, when treating invasive tumors with curative intention, one has to bear in mind the lack of histologic control and the limited depth of tissue penetration of most laser and PDT therapies...
  60. doi request reprint Somatic FGFR3 and PIK3CA mutations are present in familial seborrhoeic keratoses
    C Hafner
    Department of Dermatology, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Br J Dermatol 159:214-7. 2008
    ..We present a German family with at least seven affected members in two generations and occurrence of high numbers of SKs at an unusually young age, suggesting a hereditary background...
  61. ncbi request reprint [Truss-induced macular amyloidosis]
    C Abels
    Klinik und Poliklinik fur Dermatologie, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg
    Hautarzt 52:970-3. 2001
    ..The classification of localized cutaneous amyloidoses should include local trauma as a cause to avoid unnecessary and exhausting internal checkups to exclude systemic involvement...
  62. ncbi request reprint Microsatellite instability in malignant melanomas
    M M Kroiss
    Department of Dermatology, University of Regensburg, Germany
    Acta Derm Venereol 81:242-5. 2001
    ..We conclude that MSI occurs in a considerable subset of malignant melanomas and that there is a pattern consistent with increasing frequency of MSI with progression of melanocytic tumours...
  63. ncbi request reprint Progression and NSAID-induced apoptosis in malignant melanomas are independent of cyclooxygenase II
    T Vogt
    Department of Dermatology, University of Regensburg, D 93042 Regensburg, Germany
    Melanoma Res 11:587-99. 2001
    ..Nevertheless, Cox-II inhibitors are still candidates for therapy, though they act via an unknown mechanism...
  64. ncbi request reprint Are dermatologists in private practice interested in teledermatological services?
    A Glaessl
    Department of Dermatology, University of Regensburg, Germany
    Stud Health Technol Inform 64:185-91. 1999
    ..In our experience, for the excellence of this service an image documentation system is essential to provide the tele-dermatological expert with standardized images with constant illumination...
  65. ncbi request reprint Hereditary haemorrhagic telangiectasia treated by pulsed neodymium:yttrium-aluminium-garnet (Nd:YAG) laser (1,064 nm)
    A Werner
    Department of Dermatology, University Hospital of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Lasers Med Sci 23:385-91. 2008
    ..Pulsed Nd:YAG laser therapy (1,064 nm) appears to be an effective and safe treatment option for hereditary haemorrhagic telangiectasia on the skin of face and extremities...
  66. ncbi request reprint Keratinocyte-derived cytokines after photodynamic therapy and their paracrine induction of matrix metalloproteinases in fibroblasts
    S Karrer
    Department of Dermatology and Institute of Pathology, Molecular Pathology, University of Regensburg, 93042 Regensburg, Germany
    Br J Dermatol 151:776-83. 2004
    ....
  67. doi request reprint [Skin aging]
    E Kohl
    Klinik und Poliklinik fur Dermatologie, Universitatsklinikum Regensburg, 93053 Regensburg
    Hautarzt 60:917-33; quiz 934. 2009
    ..The importance of extrinsic factors in skin aging and the detection of its mechanisms has given rise to development of various therapeutic and preventive strategies...
  68. doi request reprint [Incoherent light in dermatology]
    P Babilas
    Klinik und Poliklinik fur Dermatologie, Universitatsklinikum Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg
    Hautarzt 61:153-65; quiz 166. 2010
    ..Both sources of light have only recently been employed in dermatology and in addition to broadband ultraviolet (UV) light sources, high-pressure gas discharge lamps, and halogen lamps enrich the armamentarium of incoherent light sources...
  69. ncbi request reprint Treatment of digital mucous cysts with a carbon dioxide laser
    S Karrer
    Department of Dermatology, University of Regensburg, Germany
    Acta Derm Venereol 79:224-5. 1999
    ..For this reason, more aggressive treatments, such as radical excision of the cyst, could be restricted to cases in which carbon dioxide laser therapy fails...
  70. ncbi request reprint Deficiency of a novel retinoblastoma binding protein 2-homolog is a consistent feature of sporadic human melanoma skin cancer
    T Vogt
    Department of Dermatology, University of Regensburg, Germany
    Lab Invest 79:1615-27. 1999
    ..The authors concluded that the loss or down-regulation of RBP2-H1 expression could be a useful molecular marker for a transformed phenotype in the human melanocytic system...
  71. ncbi request reprint Sporadic Bazex-Dupré-Christol-like syndrome: early onset basal cell carcinoma, hypohidrosis, hypotrichosis, and prominent milia
    A Glaessl
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Dermatol Surg 26:152-4. 2000
    ..The sparse hair of the scalp showed further abnormalities such as pili torti, as well as flattened, irregularly curly hairs...
  72. ncbi request reprint Mixed capillary/lymphatic malformation with coexisting port-wine stain: treatment utilizing 3D MRI and CT-guided sclerotherapy
    M B Wimmershoff
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Dermatol Surg 26:584-7. 2000
    ..Communicating via dermal lymphatic channels with superficial pseudovesicles, they can vary in size depending on the pressure transmitted by the cisterns beneath...
  73. ncbi request reprint Rapid response of IgA pemphigus of subcorneal pustular dermatosis type to treatment with isotretinoin
    C Gruss
    Department of Dermatology, University of Regensburg, Franz Josef Strauss Allee 11, D 93042 Regensburg, Germany
    J Am Acad Dermatol 43:923-6. 2000
    ..Isotretinoin was an effective drug in the treatment of subcorneal pustular dermatosis type of IgA pemphigus in this patient...
  74. ncbi request reprint Intradermal buried vertical mattress suture as sole skin closure: evaluation of 149 cases
    U Hohenleutner
    Department of Dermatology, University of Regensburg, Germany
    Acta Derm Venereol 80:344-7. 2000
    ..This suture technique is safe, easy and fast to perform, and achieves good cosmetic results without leaving suture marks...
  75. ncbi request reprint [Paraneoplastic Bazex acrokeratosis in adenocarcinoma of the stomach]
    K E Douwes
    Dermatologische Klinik und Poliklinik, Klinikum der Universitat Regensburg
    Dtsch Med Wochenschr 126:203-6. 2001
    ..Similar but less severe hyperkeratoses were found on the palms...
  76. ncbi request reprint Long-term results in the treatment of childhood hemangioma with the flashlamp-pumped pulsed dye laser: an evaluation of 617 cases
    S Hohenleutner
    Department of Dermatology, University of Regensburg, Germany
    Lasers Surg Med 28:273-7. 2001
    ..Because the treatment is fast, effective, and nearly without side effects, we recommend early laser treatment especially in superficial and small childhood hemangiomas...
  77. doi request reprint FGFR3 and PIK3CA mutations in stucco keratosis and dermatosis papulosa nigra
    C Hafner
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Br J Dermatol 162:508-12. 2010
    ..Stucco keratosis (STK) and dermatosis papulosa nigra (DPN) are referred to as variants of seborrhoeic keratosis. However, the genetic alterations involved in the pathogenesis of these benign tumours are unknown...
  78. doi request reprint Skin ageing
    E Kohl
    Department of Dermatology, Regensburg University Hospital, Regensburg, Germany
    J Eur Acad Dermatol Venereol 25:873-84. 2011
    ..The importance of extrinsic factors in skin ageing and the detection of its mechanisms have furthered the development of various therapeutic and preventive strategies...
  79. doi request reprint [Cutaneous amyloidosis]
    S Schreml
    Klinik und Poliklinik fur Dermatologie, Universitatsklinikum Regensburg, Franz Josef Strauss Allee 11, 93053, Regensburg
    Hautarzt 62:55-61; quiz 62. 2011
    ..Furthermore, the discrimination between functional and disease-causing amyloid is briefly presented...
  80. ncbi request reprint Differences in efficacy between intention-to-treat and per-protocol analyses for patients with psoriasis vulgaris and atopic dermatitis: clinical and pharmacoeconomic implications
    R Schiffner
    Department of Dermatology, University of Regensburg, 93042 Regensburg, Germany
    Br J Dermatol 144:1154-60. 2001
    ..In most studies, only results for a treatment-optimized subpopulation (patients treated according to the protocol) are presented in publications. The relevance of such data for daily routine therapy is doubtful...
  81. doi request reprint A randomized clinical trial in psoriasis: synchronous balneophototherapy with bathing in Dead Sea salt solution plus narrowband UVB vs. narrowband UVB alone (TOMESA-study group)
    A Klein
    Department of Dermatology, University Hospital Regensburg, Regensburg, Germany
    J Eur Acad Dermatol Venereol 25:570-8. 2011
    ..However, there is a lack of sufficiently large randomized controlled clinical trials evaluating the additional benefit of sBPT compared with ultraviolet B (UVB) monotherapy...
  82. ncbi request reprint [Treatment of therapy refractory verrucae vulgares with a ciclopirox-containing lacquer]
    R M Szeimies
    Klinik und Poliklinik fur Dermatologie, Klinikum der Universitat Regensburg, 93042 Regensburg
    Hautarzt 52:489-91. 2001
    ..Anti-inflammatory actions of ciclopirox, an antifungal agent, have been described previously. We assessed the effectiveness of ciclopirox in the treatment of viral warts...
  83. doi request reprint [Skin and eyes]
    E Kohl
    Klinik und Poliklinik fur Dermatologie, Universitatsklinikum Regensburg, Regensburg
    Ophthalmologe 107:281-92; quiz 293. 2010
    ..Various immunobullous disorders involve the conjunctiva with varying severity. Side effects of dermatologic treatments with glucocorticoids, antimalarials, psoralens, retinoids, or tetracyclines may involve the eye...
  84. ncbi request reprint A survey among dermatologists in practice about teledermatology
    A Glaessl
    Department of Dermatology, University of Regensburg, Germany
    Curr Probl Dermatol 32:172-5. 2003
  85. ncbi request reprint [Skin changes and anorexia nervosa]
    H Backer
    Klinik und Poliklinik fur Dermatologie, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Deutschland
    Hautarzt 58:265-72; quiz 273. 2007
    ..The diagnosis of AN can thus be facilitated by knowledge of the cutaneous manifestations, which are generally plain to see. If AN is strongly suspected, the patient should be encouraged to consult a psychiatrist/psychotherapist...
  86. ncbi request reprint Mysterious disappearance of an allogenic anterior cruciate ligament graft--a case of allergy against altered collagen
    S Karrer
    Department of Dermatology, University of Regensburg, Franz Josef Strauss Allee 11 93053, Regensburg, Germany
    Allergy 61:1148-9. 2006
  87. ncbi request reprint Role of laser therapy in dermatology -- clinical aspects
    M Landthaler
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Dermatology 208:129-34. 2004
    ..Laser therapy has become an integral part of therapeutic alternatives in dermatology. Nevertheless, there are only few statistical data on the role of lasers in everyday practice of dermatological clinics...
  88. ncbi request reprint [Correct indications for laser treatment of skin diseases]
    M Landthaler
    Dermatologische Klinik der Universität Regensburg
    Dtsch Med Wochenschr 131:1605-8. 2006
  89. ncbi request reprint Discoid lupus erythematosus and lupus profundus in childhood: a report of two cases
    M B Wimmershoff
    Department of Dermatology, University of Regensburg, Germany
    Pediatr Dermatol 20:140-5. 2003
    ..Therapy with antimalarials resulted in reduction of the skin lesions, but in one patient severe lipoatrophy occurred...
  90. ncbi request reprint [Nocardia farcinica infection of a vascular prosthesis]
    P Babilas
    Klinik und Poliklinik fur Dermatologie, Universitätsklinik Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg
    Hautarzt 58:335-7. 2007
    ..Hereupon the patient was treated purposefully with Meropenem over six months. This treatment resulted in complete recovery...
  91. ncbi request reprint [Hemorrhagic dengue fever after trip to Malaysia]
    C Hafner
    Klinik und Poliklinik für Dermatologie der Universität Regensburg
    Hautarzt 57:705-7. 2006
    ..Patients who have previously had dengue fever and retained non-neutralizing heterotypic antibodies are more likely to develop this complication via the phenomenon of antibody-dependent enhancement...
  92. ncbi request reprint [Dialysis associated skin changes]
    H Ulrich
    Klinik und Poliklinik für Dermatologie der Universitätsklinikum Regensburg, Regensburg
    Hautarzt 55:485-95; quiz 496. 2004
    ..The persisting chronic uremia is responsible for a variety of structural and functional skin changes. Dialysis or even renal transplantation leads to an improvement of some uremia associated skin disorders, others however can persist...
  93. ncbi request reprint ["Smoldering systemic mastocytosis. "Successful therapy with cladribine]
    V Schleyer
    Klinik und Poliklinik für Dermatologie der Universität Regensburg, Regensburg
    Hautarzt 55:658-62. 2004
    ..Treatment with cladribine led to an impressive improvement of skin lesions, a significant decrease in tryptase serum levels and stabilization of bone marrow infiltrates...
  94. ncbi request reprint Comparison of the 308-nm excimer laser and a 308-nm excimer lamp with 311-nm narrowband ultraviolet B in the treatment of psoriasis
    K Köllner
    Department of Dermatology, University of Regensburg, Franz Josef Strauss Allee 11, 93043 Regensburg, Germany
    Br J Dermatol 152:750-4. 2005
    ..Narrowband UVB (311 nm) phototherapy is a well-established, widely used and highly efficient treatment for psoriasis, but a big disadvantage is that large areas of unaffected skin are irradiated along with the psoriatic lesions...
  95. ncbi request reprint [Use of phytopharmaceutical agents in dermatology. Indications, therapeutic approaches and side effects]
    S Meyer
    Klinik und Poliklinik für Dermatologie der Universität Regensburg
    Hautarzt 56:483-99; quiz 500-1. 2005
    ....
  96. ncbi request reprint Primary cutaneous cryptococcosis and secondary antigenemia in a patient with long-term corticosteroid therapy
    C Hafner
    Dept of Dermatology, University of Regensburg, Franz Josef Strauss Allee 11, 93042, Regensburg, Germany
    Infection 33:86-9. 2005
    ..The clinical and microbiological characteristics of this patient as well as therapeutical and epidemiological aspects of primary cutaneous cryptococcosis (PCC) are discussed...
  97. ncbi request reprint [Anaphylactic reaction following hair bleaching]
    P Babilas
    Klinik und Poliklinik fur Dermatologie, Klinikum der Universitat Regensburg
    Hautarzt 56:1152-5. 2005
    ..The patient also developed an anaphylactic reaction three hours following patch testing with the hairdresser battery. The rub test with ammonium persulphate (2.5%) in a 1:100 solution was positive...
  98. ncbi request reprint Optimizing treatment parameters for hair removal using long-pulsed Nd:YAG-lasers
    K Raff
    Department of Dermatology, University of Regensburg, Franz Josef Strauss Allee 11, 93053, Regensburg, Germany
    Lasers Med Sci 18:219-22. 2004
    ..Although the different treatment parameters did not lead to a lot of differing hair reduction 12 months after the last treatment, the laser with the largest spot size and the longest pulse time showed the best results...
  99. ncbi request reprint [Long-term course of necrobiotic xanthogranuloma with ocular involvement]
    S Meyer
    Klinik und Poliklinik fur Dermatologie, Universitat, 93042 Regensburg
    Hautarzt 57:144-9. 2006
    ..None of these therapeutic approaches, however, showed a satisfying long-term effect. At present the patient is undergoing cyclophosphamide-dexamethasone pulse therapy...
  100. doi request reprint The impact of the pH value on skin integrity and cutaneous wound healing
    S Schreml
    Department of Dermatology, Regensburg University Hospital, Regensburg, Germany
    J Eur Acad Dermatol Venereol 24:373-8. 2010
    ..However, wound pH is rarely taken into account in current wound therapy strategies. A routinely performed monitoring of the wound pH and a subsequently adapted wound therapy would most possibly improve chronic wound therapy...
  101. ncbi request reprint Laser therapy of vascular lesions
    M Landthaler
    Department of Dermatology, University Clinic Regensburg, Regensburg, Germany
    Photodermatol Photoimmunol Photomed 22:324-32. 2006
    ..Various lasers can be used for the treatment of different vascular and non-vascular lesions. According to our results, vascular lesions constitute the most important indication for laser therapy in dermatology...