D Buchheidt

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi request reprint Systemic infections with Candida sp. and Aspergillus sp. in immunocompromised patients with hematological malignancies: current serological and molecular diagnostic methods
    D Buchheidt
    Medizinische Universitatsklinik, Klinikum Mannheim der Universität Heidelberg, Mannheim, Deutschland
    Chemotherapy 46:219-28. 2000
  2. pmc Development of a LightCycler PCR assay for detection and quantification of Aspergillus fumigatus DNA in clinical samples from neutropenic patients
    Birgit Spiess
    III Medizinische Klinik, Universitatsklinikum Mannheim, University of Heidelberg, D 68305 Mannheim, Germany
    J Clin Microbiol 41:1811-8. 2003
  3. doi request reprint Molecular diagnosis of invasive aspergillosis in patients with hematologic malignancies - new answers to a diagnostic challenge?
    Dieter Buchheidt
    Professor University of Heidelberg, Mannheim University Hospital, 3 Medizinische Klinik 3rd Department of Internal Medicine, Theodor Kutzer Ufer 1 3, D 68167 Mannheim, Germany 49 621 383 4115 49 621 383 4201
    Expert Opin Med Diagn 2:753-61. 2008
  4. ncbi request reprint Current molecular diagnostic approaches to systemic infections with aspergillus species in patients with hematological malignancies
    Dieter Buchheidt
    3 Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Germany
    Leuk Lymphoma 45:463-8. 2004
  5. ncbi request reprint Management of infections in critically ill neutropenic cancer patients
    Dieter Buchheidt
    Intensive Care Unit, III Medizinische Klinik, Universitatsklinikum Mannheim, University of Heidelberg, Germany
    J Crit Care 19:165-73. 2004
  6. ncbi request reprint Diagnosis and treatment of documented infections in neutropenic patients--recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
    Dieter Buchheidt
    III Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Wiesbadener Strasse 7 11, 68305, Mannheim, Germany
    Ann Hematol 82:S127-32. 2003
  7. ncbi request reprint Aspergillus polymerase chain reaction (PCR) diagnosis
    D Buchheidt
    3 Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Germany
    Med Mycol 43:S139-45. 2005
  8. ncbi request reprint Prospective clinical evaluation of a LightCycler-mediated polymerase chain reaction assay, a nested-PCR assay and a galactomannan enzyme-linked immunosorbent assay for detection of invasive aspergillosis in neutropenic cancer patients and haematological s
    Dieter Buchheidt
    III Medizinische Klinik, Universitaetsklinikum Mannheim, Universitaet Heidelberg, Wiesbadenerstrasse 7 11, D 68305 Mannheim, Germany
    Br J Haematol 125:196-202. 2004
  9. ncbi request reprint Pseudomembranous tracheobronchial aspergillosis: a rare manifestation of invasive aspergillosis in a non-neutropenic patient with Hodgkin's disease
    D Buchheidt
    III Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Germany
    Mycoses 46:51-5. 2003
  10. ncbi request reprint Clinical evaluation of a polymerase chain reaction assay to detect Aspergillus species in bronchoalveolar lavage samples of neutropenic patients
    Dieter Buchheidt
    III Medizinische Universitätsklinik, Klinikum Mannheim, Mannheim, Germany
    Br J Haematol 116:803-11. 2002

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Systemic infections with Candida sp. and Aspergillus sp. in immunocompromised patients with hematological malignancies: current serological and molecular diagnostic methods
    D Buchheidt
    Medizinische Universitatsklinik, Klinikum Mannheim der Universität Heidelberg, Mannheim, Deutschland
    Chemotherapy 46:219-28. 2000
    ..The clinical value, the advantages and remaining problems of recently developed, more sensitive and specific serological assays and molecular methods are reviewed...
  2. pmc Development of a LightCycler PCR assay for detection and quantification of Aspergillus fumigatus DNA in clinical samples from neutropenic patients
    Birgit Spiess
    III Medizinische Klinik, Universitatsklinikum Mannheim, University of Heidelberg, D 68305 Mannheim, Germany
    J Clin Microbiol 41:1811-8. 2003
    ....
  3. doi request reprint Molecular diagnosis of invasive aspergillosis in patients with hematologic malignancies - new answers to a diagnostic challenge?
    Dieter Buchheidt
    Professor University of Heidelberg, Mannheim University Hospital, 3 Medizinische Klinik 3rd Department of Internal Medicine, Theodor Kutzer Ufer 1 3, D 68167 Mannheim, Germany 49 621 383 4115 49 621 383 4201
    Expert Opin Med Diagn 2:753-61. 2008
    ....
  4. ncbi request reprint Current molecular diagnostic approaches to systemic infections with aspergillus species in patients with hematological malignancies
    Dieter Buchheidt
    3 Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Germany
    Leuk Lymphoma 45:463-8. 2004
    ..The clinical value, advantages and remaining problems of recently developed molecular approaches to detect the emerging fungal pathogen are reviewed...
  5. ncbi request reprint Management of infections in critically ill neutropenic cancer patients
    Dieter Buchheidt
    Intensive Care Unit, III Medizinische Klinik, Universitatsklinikum Mannheim, University of Heidelberg, Germany
    J Crit Care 19:165-73. 2004
    ..A multidisciplinary practical approach to evaluation and treatment is needed to optimize treatment results and to meet the various diagnostic and therapeutic challenges in this subset of patients on an intensive care unit...
  6. ncbi request reprint Diagnosis and treatment of documented infections in neutropenic patients--recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
    Dieter Buchheidt
    III Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Wiesbadener Strasse 7 11, 68305, Mannheim, Germany
    Ann Hematol 82:S127-32. 2003
    ..The response rate is significantly lower in documented infections than in fever of unknown origin (FUO). Evidence-based recommendations for diagnosis and treatment procedures are presented, reflecting study results and expert opinions...
  7. ncbi request reprint Aspergillus polymerase chain reaction (PCR) diagnosis
    D Buchheidt
    3 Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Germany
    Med Mycol 43:S139-45. 2005
    ..The clinical value, advantages and remaining problems of PCR approaches to detect the emerging fungal pathogen are reviewed...
  8. ncbi request reprint Prospective clinical evaluation of a LightCycler-mediated polymerase chain reaction assay, a nested-PCR assay and a galactomannan enzyme-linked immunosorbent assay for detection of invasive aspergillosis in neutropenic cancer patients and haematological s
    Dieter Buchheidt
    III Medizinische Klinik, Universitaetsklinikum Mannheim, Universitaet Heidelberg, Wiesbadenerstrasse 7 11, D 68305 Mannheim, Germany
    Br J Haematol 125:196-202. 2004
    ..In patients at high risk for IA, positive results for Aspergillus by PCR of blood samples are highly suggestive for IA and contribute to the diagnosis...
  9. ncbi request reprint Pseudomembranous tracheobronchial aspergillosis: a rare manifestation of invasive aspergillosis in a non-neutropenic patient with Hodgkin's disease
    D Buchheidt
    III Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Germany
    Mycoses 46:51-5. 2003
    ..What is crucial for the clinical management is an early diagnosis by bronchoscopy and cultural proof of the pathogen followed by an adequate antifungal treatment...
  10. ncbi request reprint Clinical evaluation of a polymerase chain reaction assay to detect Aspergillus species in bronchoalveolar lavage samples of neutropenic patients
    Dieter Buchheidt
    III Medizinische Universitätsklinik, Klinikum Mannheim, Mannheim, Germany
    Br J Haematol 116:803-11. 2002
    ..4%, the positive predictive value 83.8%, the negative predictive value 98.1%. Our data support the considerable clinical value of this PCR assay for confirming and improving diagnosis of pulmonary aspergillosis in high-risk patients...
  11. ncbi request reprint Systemic infections with Aspergillus species in patients with hematological malignancies: current serological and molecular diagnostic approaches
    D Buchheidt
    3 Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Germany
    Onkologie 24:531-6. 2001
    ..The clinical value, advantages and remaining problems of recently developed serological assays and molecular approaches to detect this emerging pathogen are reviewed...
  12. ncbi request reprint Detection of Aspergillus species in blood and bronchoalveolar lavage samples from immunocompromised patients by means of 2-step polymerase chain reaction: clinical results
    D Buchheidt
    III Medizinische Universitaetsklinik, Klinikum Mannheim, Fakultaet fuer Klinische Medizin Mannheim, Ruprecht Karls Universitaet Heidelberg, Mannheim, Germany
    Clin Infect Dis 33:428-35. 2001
    ..Our data suggest that this PCR method has possible clinical value for confirming and improving the diagnosis of invasive aspergillosis in high-risk patients...
  13. pmc Aspergillus PCR-based investigation of fresh tissue and effusion samples in patients with suspected invasive Aspergillosis enhances diagnostic capabilities
    M Reinwald
    Mannheim University Hospital, University of Heidelberg, Heidelberg, Germany
    J Clin Microbiol 51:4178-85. 2013
    ..Thus, PCR testing of these specimens enhances the diagnostic capabilities. ..
  14. pmc Detection of Aspergillus DNA in cerebrospinal fluid from patients with cerebral aspergillosis by a nested PCR assay
    M Hummel
    III Medizinische Universitätsklinik, Fakultät für Klinische Medizin Mannheim, Universitat Heidelberg, Germany
    J Clin Microbiol 44:3989-93. 2006
    ..Further prospective studies with larger numbers of patients must be performed to evaluate the clinical significance of Aspergillus PCR with CSF samples...
  15. ncbi request reprint Galactomannan enzyme immunoassay for monitoring systemic infection with Aspergillus fumigatus in mice
    M Kretschmar
    , Klinikum Mannheim, D-68135, Mannheim, Germany
    Diagn Microbiol Infect Dis 41:107-12. 2001
    ..Therefore, the test was excellent for detection of early i.v. infection with Aspergillus fumigatus but not suited for detection of limited organ infection in immunocompetent mice...
  16. doi request reprint Diagnosis of invasive fungal infections in haematological patients by combined use of galactomannan, 1,3-β-D-glucan, Aspergillus PCR, multifungal DNA-microarray, and Aspergillus azole resistance PCRs in blood and bronchoalveolar lavage samples: results of
    T Boch
    Department of Hematology and Oncology, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany Electronic address
    Clin Microbiol Infect 22:862-868. 2016
    ..Combination of biomarkers is superior to their sole use in diagnosing IFD, particularly IA. Integrating blood and BAL samples into a diagnostic algorithm is an advantageous approach...
  17. doi request reprint Detection of Aspergillus DNA by a nested PCR assay is able to improve the diagnosis of invasive aspergillosis in paediatric patients
    Margit Hummel
    III Medizinische Universitätsklinik, Medizinische Fakultat Mannheim, Universitat Heidelberg, D 68167 Mannheim, Germany
    J Med Microbiol 58:1291-7. 2009
    ..Our nested PCR assay was able to detect Aspergillus DNA in blood, cerebrospinal fluid and bronchoalveolar lavage samples from paediatric and adolescent patients with IA with high sensitivity and specificity rates...
  18. doi request reprint Assessment of Aspergillus-specific PCR as a screening method for invasive aspergillosis in paediatric cancer patients and allogeneic haematopoietic stem cell recipients with suspected infections
    M Reinwald
    Department of Hematology and Oncology, Mannheim University Hospital, Mannheim, Germany
    Mycoses 57:537-43. 2014
    ..Harnessing PCR for diagnosis of IA should thus be focused on blood analyses of more homogenous high-risk patients and/or analyses of bronchoalveolar lavage, tissue or cerebrospinal fluid specimens...
  19. ncbi request reprint Impact of chemoradiotherapy-induced anemia on survival in uniformly staged patients with locally advanced squamous cell carcinoma of the esophagus
    R D Hofheinz
    Okologisches Zentrum, III, Medizinische Klinik, Fakultät für Klinische Medizin Mannheim der Universität Heidelberg, Germany
    Onkologie 27:462-6. 2004
    ....
  20. ncbi request reprint Diagnostic yield of bronchoscopy with bronchoalveolar lavage in febrile patients with hematologic malignancies and pulmonary infiltrates
    Margit Hummel
    3 Medizinische Klinik, Universitatsklinikum Mannheim, University of Heidelberg, Mannheim, Germany
    Ann Hematol 87:291-7. 2008
    ....
  21. doi request reprint Aspergillus PCR testing: results from a prospective PCR study within the AmBiLoad trial
    Margit Hummel
    III Medizinische Klinik, Klinikum Mannheim, University of Heidelberg, Mannheim, Germany
    Eur J Haematol 85:164-9. 2010
    ..In a subset of patients treated within the AmBiLoad Trial, samples were investigated prospectively by a nested Aspergillus PCR assay to re-evaluate the significance of PCR in this setting...
  22. ncbi request reprint Comparison of glucan detection and galactomannan enzyme immunoassay in gastrointestinal and systemic murine candidiasis
    Thomas Nichterlein
    Institut fur Medizinische Mikrobiologie und Hygiene, Klinikum Mannheim, D 68167 Mannheim, Germany
    Diagn Microbiol Infect Dis 46:103-8. 2003
    ..Therefore, in the mouse model used, glucan detection appeared to be superior for differentiation between colonization and dissemination...
  23. ncbi request reprint Recurrent chemotherapy-induced tumor lysis syndrome (TLS) with renal failure in a patient with chronic lymphocytic leukemia - successful treatment and prevention of TLS with low-dose rasburicase
    Margit Hummel
    III Medizinische Klinik, Klinikum Mannheim, University of Heidelberg, Mannheim, Germany
    Eur J Haematol 75:518-21. 2005
    ..In several studies, rasburicase, given at a dose of 0.15-0.2 mg/kg for up to 7 d, proved to be highly effective in lowering urate levels...
  24. ncbi request reprint Effective treatment and prophylaxis of hyperuricemia and impaired renal function in tumor lysis syndrome with low doses of rasburicase
    Margit Hummel
    III Medizinische Klinik, Klinikum Mannheim, University of Heidelberg, Mannheim, Germany
    Eur J Haematol 80:331-6. 2008
    ..Rasburicase proved to be effective in rapidly reducing UA levels. Costs of rasburicase average up to 4500 euros. To assess if lower doses of rasburicase are effective, we treated patients with lower doses than recommended...
  25. ncbi request reprint Two potential mechanisms of oxaliplatin-induced haemolytic anaemia in a single patient
    Ralf Dieter Hofheinz
    III Medical Clinic, University Hospital Mannheim, University of Heidelberg, Wiesbadener Strasse 7 11, 68167 Mannheim, Germany
    Cancer Chemother Pharmacol 53:276-7. 2004
    ..We report here a third patient with an immune-haematological finding favouring a bispecific mechanism (immune-complex and penicillin type) of oxaliplatin-induced haemolysis...
  26. ncbi request reprint Severe Chlamydia pneumoniae infection in a patient with mild neutropenia during treatment of Hodgkin's disease
    Margit Hummel
    III Medizinische Klinik, Department of Hematology Oncology, Klinikum Mannheim, University of Heidelberg, Germany
    Ann Hematol 83:441-3. 2004
    ..We report the case of a patient with Hodgkin's disease who developed C. pneumoniae pneumonia during mild neutropenia. C. pneumoniae should be considered as a causative agent of pneumonia in neutropenic patients...
  27. ncbi request reprint Detection of Aspergillus DNA by a nested PCR assay is superior to blood culture in an experimental murine model of invasive aspergillosis
    Margit Hummel
    III Medizinische Klinik, Universitäts klinikum Mannheim, Universitat Heidelberg, D 68305 Mannheim, Germany
    J Med Microbiol 53:803-6. 2004
    ..6 and 87.5 % depending on the fungal burden. In conclusion, the nested PCR assay is superior to cultural methods in detecting Aspergillus spp. in murine blood samples...
  28. doi request reprint Identification of invasive fungal diseases in immunocompromised patients by combining an Aspergillus specific PCR with a multifungal DNA-microarray from primary clinical samples
    T Boch
    Department of Hematology and Oncology, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany
    Mycoses 58:735-45. 2015
    ....
  29. ncbi request reprint Spontaneous remission in adult acute myeloid leukemia in association with systemic bacterial infection-case report and review of the literature
    O Maywald
    III Medizinische Universitätsklinik, Fakultät für Klinische Medizin Mannheim der Universität Heidelberg, Wiesbadener Strasse 7 11, 68305, Mannheim, Germany
    Ann Hematol 83:189-94. 2004
    ..Possible mechanisms of this phenomenon are discussed with a review of the literature...
  30. doi request reprint Diagnostic yield of blood cultures from antibiotic-naïve and antibiotically treated patients with haematological malignancies and high-risk neutropenia
    Margit Hummel
    III Medizinische Universitätsklinik, Medizinische Fakultat Mannheim, Universitat Heidelberg, Mannheim, Germany
    Scand J Infect Dis 41:650-5. 2009
    ..The epidemiological data obtained are helpful for selecting empirical antibiotic treatment regimens...
  31. ncbi request reprint Molecular and serological diagnosis of invasive aspergillosis: new answers to old questions?
    Margit Hummel
    3, Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Mannheim, Germany
    Mycoses 50:18-23. 2007
    ..The clinical value, advantages and problems of current molecular and serological approaches to diagnose IA are reviewed...
  32. doi request reprint Patients with malignant hematological disorders treated on a palliative care unit: prognostic impact of clinical factors
    M Kripp
    III Medizinische Klinik, Universitatsmedizin Mannheim, Universitat Heidelberg, Theodor Kutzer Ufer 1 3, 68167, Mannheim, Germany
    Ann Hematol 93:317-25. 2014
    ..These parameters might help clinicians to estimate prognosis of remaining life span and individualize treatment and/or end-of-life care options for patients. ..
  33. pmc DNA microarray-based detection and identification of fungal pathogens in clinical samples from neutropenic patients
    Birgit Spiess
    III Medizinische Universitätsklinik, Medizinische Fakultät Mannheim der Universität Heidelberg, Theodor Kutzer Ufer 1 3, D 68167, Mannheim, Germany
    J Clin Microbiol 45:3743-53. 2007
    ..The assay detected genomic DNA from 14 fungal pathogens from the clinical samples, pointing to a high significance for improving the diagnosis of IFI...
  34. ncbi request reprint [Echocardiographic detection of tricuspid valve endocarditis and right atrial and ventricular masses in a patient with acute myeloid leukaemia]
    D Buchheidt
    Medizinische Klinik, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Germany
    Ultraschall Med 23:341-4. 2002
    ..This case report confirms the great importance of sonography in the management of fever of unknown origin in immunocompromised patients...
  35. ncbi request reprint Surgical interventions in patients with hematologic malignancies
    Peter Hohenberger
    Division of Surgical Oncology and Thoracic Surgery, University Hospital Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1 3, D 68167 Mannheim, Germany
    Crit Rev Oncol Hematol 55:83-91. 2005
    ....
  36. ncbi request reprint IgA nephropathy and hodgkin's disease: a rare coincidence. Case report and literature review
    Jörg Bergmann
    Third Department of Internal Medicine Hematology Oncology, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany
    Am J Kidney Dis 45:e16-9. 2005
    ..Treatment with the bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone regimen resulted in complete hematologic and renal remission for more than 1 year after diagnosis...
  37. ncbi request reprint Phase II study of plitidepsin in pretreated patients with locally advanced or metastatic non-small cell lung cancer
    Christian Peschel
    Technische Universitat, III Medizinische Klinik, Munchen, Germany
    Lung Cancer 60:374-80. 2008
    ..v. infusion at a dose of 5mg/m(2), every 2 weeks, to patients with chemotherapy pretreated advanced non-small cell lung cancer (NSCLC)...
  38. ncbi request reprint Fatal cerebral involvement in systemic aspergillosis: a rare complication of steroid-treated autoimmune bicytopenia
    Dieter Buchheidt
    Eur J Haematol 72:375-6. 2004
  39. doi request reprint Central venous catheter-related infections in hematology and oncology : guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
    Hans Heinrich Wolf
    Klinik für Innere Medizin IV, Onkologie, Hämatologie und Hämostaseologie, Martin Luther Universität Halle, Ernst Grube Str 40, 06120 Halle, Germany
    Ann Hematol 87:863-76. 2008
    ..aureus and Candida infections, as well as in case of tunnel or pocket infections. Future studies will elucidate whether the rate of CRI in neutropenic patients may be reduced by catheters impregnated with antimicrobial agents...
  40. ncbi request reprint Diagnosis and antimicrobial therapy of pulmonary infiltrates in febrile neutropenic patients--guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
    Georg Maschmeyer
    Dept of Hematology and Oncology, Charite University Hospital, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany
    Ann Hematol 82:S118-26. 2003
    ....
  41. ncbi request reprint Central venous catheter (CVC)-related infections in neutropenic patients--guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
    Gerd Fatkenheuer
    Klinik 1 für Innere Medizin, Klinikum der Universität zu Köln, 50924, Koln, Germany
    Ann Hematol 82:S149-57. 2003
    ..In the future, the rate of catheter-related infections in neutropenic patients may be reduced by the use of catheters coated with antimicrobial agents...
  42. ncbi request reprint IgMA-enriched immunoglobulin in neutropenic patients with sepsis syndrome and septic shock: a randomized, controlled, multiple-center trial
    Marcus Hentrich
    Department of Internal Medicine III, University Hospital Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
    Crit Care Med 34:1319-25. 2006
    ..To evaluate the effect of intravenous IgMA-enriched immunoglobulin (ivIGMA) therapy on mortality in neutropenic patients with hematologic malignancies and sepsis syndrome or septic shock...
  43. ncbi request reprint Management of sepsis in neutropenia: guidelines of the infectious diseases working party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
    Olaf Penack
    Klinik für Hämatologie, Onkologie and Transfusionsmedizin, Charite Campus Benjamin Franklin, Berlin, Germany German Society ofHematology and Oncology
    Ann Hematol 85:424-33. 2006
    ..The guidelines are written for clinicians and focus on pathophysiology, diagnosis, and treatment of sepsis. The manuscript contains evidence-based recommendations for the assessment of the quality and strength of the data...
  44. ncbi request reprint Long-term survival in patients with acute leukemia and chronic disseminated candidiasis despite minimal antileukemic therapy
    Meinholf Karthaus
    Haematologica 91:1422-3. 2006
    ..However, despite minimal antileukemic treatment, all patients remained in complete remission. Immunologic mechanisms associated with CDC might have had an antileukemic effect...
  45. ncbi request reprint A double-blind trial on prophylactic voriconazole (VRC) or placebo during induction chemotherapy for acute myelogenous leukaemia (AML)
    Jörg J Vehreschild
    Klinikum der Universität zu Köln, Klinik I fur Innere Medizin, Studienzentrum Infektiologie II, 50937 Koln, Germany
    J Infect 55:445-9. 2007
    ..We conducted a trial to analyze the efficacy and safety of voriconazole in the prevention of lung infiltrates during induction chemotherapy for acute myelogenous leukaemia (AML)...
  46. ncbi request reprint Prophylaxis of invasive fungal infections in patients with hematological malignancies and solid tumors--guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
    Oliver A Cornely
    Klinik I fur Innere Medizin, Klinikum der Universität zu Köln, 50931, Koln, Germany
    Ann Hematol 82:S186-200. 2003
    ..The objective of this review accumulating information on about 10.000 patients is to assess evidence based criteria primarily regarding the efficacy of antifungal prophylaxis in neutropenic cancer patients...
  47. ncbi request reprint Systematic identification of substrates for profiling of secreted proteases from Aspergillus species
    René Schaal
    Institute for Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Theodor Kutzer Ufer 1 3, D 68167 Mannheim, Germany
    J Microbiol Methods 71:93-100. 2007
    ..These reporter peptides might be feasible for future protease profiling of serum specimens to improve diagnosis and monitoring of invasive aspergillosis...