Julian Bösel

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. doi [News and perspectives in neurocritical care]
    J Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland
    Nervenarzt 85:928-38. 2014
  2. doi Management of the Interventional Stroke Patient
    Julian Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Curr Treat Options Neurol 17:45. 2015
  3. doi Tracheostomy in stroke patients
    Julian Bösel
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Curr Treat Options Neurol 16:274. 2014
  4. doi [Intensive care therapy of space-occupying large hemispheric infarction. Summary of the NCS/DGNI guidelines]
    J Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland
    Nervenarzt 86:1018-29. 2015
  5. doi [Sedation and weaning in neurocritical care: can concepts from general critical care be applied?]
    J Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Deutschland
    Nervenarzt 83:1533-41. 2012
  6. doi Stroke-related Early Tracheostomy versus Prolonged Orotracheal Intubation in Neurocritical Care Trial (SETPOINT): a randomized pilot trial
    Julian Bösel
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg D 69121, Germany
    Stroke 44:21-8. 2013
  7. doi [Survey study: update on neurological intensive care in Germany 2012: structure, standards and scores in neurological intensive care units]
    J Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Deutschland
    Nervenarzt 83:1609-18. 2012
  8. doi Volatile isoflurane sedation in cerebrovascular intensive care patients using AnaConDa(®): effects on cerebral oxygenation, circulation, and pressure
    Julian Bösel
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Intensive Care Med 38:1955-64. 2012
  9. doi Treatment of acute ischemic stroke with clot retrieval devices
    Julian Bösel
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, D 69120, Heidelberg, Germany
    Curr Treat Options Cardiovasc Med 14:260-72. 2012
  10. doi Benefits of early tracheostomy in ventilated stroke patients? Current evidence and study protocol of the randomized pilot trial SETPOINT (Stroke-related Early Tracheostomy vs. Prolonged Orotracheal Intubation in Neurocritical care Trial)
    Julian Bösel
    Department of Neurology, University of Heidelberg, Germany
    Int J Stroke 7:173-82. 2012

Collaborators

Detail Information

Publications36

  1. doi [News and perspectives in neurocritical care]
    J Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland
    Nervenarzt 85:928-38. 2014
    ..The application of these measures to brain diseases and injuries frequently treated in neurointensive care units will be addressed in the context of current studies...
  2. doi Management of the Interventional Stroke Patient
    Julian Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Curr Treat Options Neurol 17:45. 2015
    ..Periinterventional management will significantly affect the success of recanalization...
  3. doi Tracheostomy in stroke patients
    Julian Bösel
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Curr Treat Options Neurol 16:274. 2014
    ..Decannulation of stroke patients after discontinued ventilation has to follow reliable confirmation of swallowing ability, as by endoscopy...
  4. doi [Intensive care therapy of space-occupying large hemispheric infarction. Summary of the NCS/DGNI guidelines]
    J Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland
    Nervenarzt 86:1018-29. 2015
    ..Subsequently, evidence-based recommendations were compiled after weighing the advantages against the disadvantages of certain management options. This is a commented abridged version of the results of the consensus conference. ..
  5. doi [Sedation and weaning in neurocritical care: can concepts from general critical care be applied?]
    J Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Deutschland
    Nervenarzt 83:1533-41. 2012
    ....
  6. doi Stroke-related Early Tracheostomy versus Prolonged Orotracheal Intubation in Neurocritical Care Trial (SETPOINT): a randomized pilot trial
    Julian Bösel
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg D 69121, Germany
    Stroke 44:21-8. 2013
    ..Optimal timing of tracheostomy in ventilated patients with severe stroke is unclear. We aimed to investigate feasibility, safety, and potential advantages of early tracheostomy in these intensive care unit (ICU) patients...
  7. doi [Survey study: update on neurological intensive care in Germany 2012: structure, standards and scores in neurological intensive care units]
    J Bösel
    Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Deutschland
    Nervenarzt 83:1609-18. 2012
    ..Furthermore, it is presently rather unclear as to what extent German neurological intensivists adhere to guidelines, employ standard operating procedures or use scoring tools...
  8. doi Volatile isoflurane sedation in cerebrovascular intensive care patients using AnaConDa(®): effects on cerebral oxygenation, circulation, and pressure
    Julian Bösel
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Intensive Care Med 38:1955-64. 2012
    ..We investigated the effects of isoflurane sedation on cerebral and systemic physiology parameters in neuromonitored ICU stroke patients...
  9. doi Treatment of acute ischemic stroke with clot retrieval devices
    Julian Bösel
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, D 69120, Heidelberg, Germany
    Curr Treat Options Cardiovasc Med 14:260-72. 2012
    ..This problem urgently needs to be addressed in a prospective randomized fashion and improvements of treatment be recognized and implemented before clot retrieval can be considered an established form of acute stroke treatment...
  10. doi Benefits of early tracheostomy in ventilated stroke patients? Current evidence and study protocol of the randomized pilot trial SETPOINT (Stroke-related Early Tracheostomy vs. Prolonged Orotracheal Intubation in Neurocritical care Trial)
    Julian Bösel
    Department of Neurology, University of Heidelberg, Germany
    Int J Stroke 7:173-82. 2012
    ..It is completely unclear whether ventilated stroke patients might benefit from early tracheostomy, too...
  11. ncbi The utility of cardiovascular drugs in the treatment of cerebrovascular disease
    Julian Bösel
    University Hospital Heidelberg, Department of Neurology, Im Neuenheimer Feld 400, D 69120 Heidelberg, Germany
    Curr Opin Investig Drugs 11:1015-24. 2010
    ..Ongoing trials and preclinical research of promising agents and treatment strategies are also discussed...
  12. doi DESTINY II: DEcompressive Surgery for the Treatment of malignant INfarction of the middle cerebral arterY II
    Eric Juttler
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Int J Stroke 6:79-86. 2011
    ..This leads to great uncertainty in everyday clinical practice...
  13. doi Effect of Conscious Sedation vs General Anesthesia on Early Neurological Improvement Among Patients With Ischemic Stroke Undergoing Endovascular Thrombectomy: A Randomized Clinical Trial
    Silvia Schönenberger
    Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany
    JAMA 316:1986-1996. 2016
    ..Optimal management of sedation and airway during thrombectomy for acute ischemic stroke is controversial due to lack of evidence from randomized trials...
  14. pmc Mechanical thrombectomy using a combined CT/C-arm X-ray system
    Johannes Pfaff
    Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany
    J Neurointerv Surg 8:621-5. 2016
    ..MT is usually performed in a dedicated angiography suite using a floor- and/or ceiling-mounted biplane angiographic system. Here we report our first experience of MT with a new combined CT and mobile C-arm X-ray device setup...
  15. doi Hemicraniectomy in older patients with extensive middle-cerebral-artery stroke
    Eric Juttler
    From the Departments of Neurology E J, J B, H A, W H and Neurosurgery A U, O W S, the Institute of Medical Biometry and Informatics M G, P S, R L, and the Coordination Center for Clinical Trials S L, University of Heidelberg, Heidelberg, The Department of Neurology, University of Ulm, University and Rehabilitation Hospitals, Ulm E J, the Center for Stroke Research Berlin E J and the Department of Neurosurgery J W, Charite Universitatsmedizin Berlin, Berlin, the Departments of Neurology H S and Neurosurgery T P, University of Dresden, Dresden, and the Departments of Neurology C H and Neurosurgery J M, University of Leipzig, Leipzig all in Germany
    N Engl J Med 370:1091-100. 2014
    ..Its benefit in older patients is uncertain...
  16. doi Induction of cooling with a passive head and neck cooling device: effects on brain temperature after stroke
    Sven Poli
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 44:708-13. 2013
    ..We conducted this study to investigate the relationship between surface head/neck cooling and brain temperature...
  17. doi One-pass endovascular treatment of intracranial atherosclerotic stenosis with a novel PTA balloon and self-expanding microstent
    Markus A Möhlenbruch
    Department of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany
    Neuroradiology 58:893-9. 2016
    ....
  18. doi Sedation vs. Intubation for Endovascular Stroke TreAtment (SIESTA) - a randomized monocentric trial
    Silvia Schönenberger
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Int J Stroke 10:969-78. 2015
    ..According to retrospective studies, the widely favored general anesthesia with intubation seems to be associated with poor functional outcome compared to a slightly sedated non-intubated condition (conscious sedation)...
  19. doi Fast-track intubation for accelerated interventional stroke treatment
    Oliver Herrmann
    Department of Neurology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Neurocrit Care 17:354-60. 2012
    ..The aim of this study was to identify factors delaying door-to-treatment times, and to evaluate the effect of a fast-track intubation standard operating procedure (I-SOP) on door-to-angiography time...
  20. doi Cerebral oxygen transport failure?: decreasing hemoglobin and hematocrit levels after ischemic stroke predict poor outcome and mortality: STroke: RelevAnt Impact of hemoGlobin, Hematocrit and Transfusion (STRAIGHT)--an observational study
    Lars Kellert
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Stroke 42:2832-7. 2011
    ..Although conceivably relevant for penumbra oxygenation, the optimal levels of hemoglobin (Hb) and hematocrit (Hct) in patients with acute ischemic stroke are unknown...
  21. pmc Low hemoglobin is associated with poor functional outcome after non-traumatic, supratentorial intracerebral hemorrhage
    Jennifer Diedler
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg, Germany
    Crit Care 14:R63. 2010
    ..Here, we assessed the relationship between hemoglobin (HB) levels and clinical outcome after ICH...
  22. ncbi Development and Validation of an Automatic Segmentation Algorithm for Quantification of Intracerebral Hemorrhage
    Moritz Scherer
    From the Department of Neurosurgery M S, A Y, Y A S, A Ü, B O, Institute of Medical Biometry and Informatics IMBI C S, and Department of Neurology J B, University Hospital Heidelberg, Germany Junior Group Medical Image Computing, German Cancer Research Center DKFZ, Heidelberg, Germany J C, M G, K M H and Division of Neuroradiology, Heidelberg University Hospital, Germany M M
    Stroke 47:2776-2782. 2016
    ..The aim of this study was to establish and validate an automatic segmentation algorithm, allowing for quick and accurate quantification of ICH...
  23. doi Fresh frozen plasma versus prothrombin complex concentrate in patients with intracranial haemorrhage related to vitamin K antagonists (INCH): a randomised trial
    Thorsten Steiner
    Department of Neurology, Klinikum Frankfurt Höchst, Frankfurt, Germany Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany Electronic address
    Lancet Neurol 15:566-73. 2016
    ..We assessed the safety and efficacy of fresh frozen plasma (FFP) versus prothrombin complex concentrate (PCC) in patients with VKA-ICH...
  24. doi The SETscore to Predict Tracheostomy Need in Cerebrovascular Neurocritical Care Patients
    Silvia Schönenberger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Neurocrit Care 25:94-104. 2016
    ..The optimal time point for TT remains unclear and a controversy in everyday NICU life. Here, we prospectively evaluated a score for prediction of TT need in NICU patients with cerebrovascular disease...
  25. doi Early tracheostomy in ventilated stroke patients: Study protocol of the international multicentre randomized trial SETPOINT2 (Stroke-related Early Tracheostomy vs. Prolonged Orotracheal Intubation in Neurocritical care Trial 2)
    Silvia Schönenberger
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Int J Stroke 11:368-79. 2016
    ..The optimal timing for tracheostomy is still unknown, and it is controversial whether early tracheostomy impacts upon functional outcome...
  26. doi Minimally invasive endoscopic surgery for treatment of spontaneous intracerebral haematomas
    Christopher Beynon
    Department of Neurosurgery, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Neurosurg Rev 38:421-8; discussion 428. 2015
    ..In addition, the modalities of the surgical procedure at the authors' institution are described. Controlled clinical trials are needed to evaluate the full potential and limitations of this promising technique...
  27. doi Circulatory and Respiratory Parameters during Acute Endovascular Stroke Therapy in Conscious Sedation or General Anesthesia
    Sibu Mundiyanapurath
    Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany Electronic address
    J Stroke Cerebrovasc Dis 24:1244-9. 2015
    ..The underlying mechanisms are unknown, but hypotension and hypocapnia during GA have been suggested. There are no prospective data on this question...
  28. pmc Noninvasive cerebral oximetry during endovascular therapy for acute ischemic stroke: an observational study
    Christian Hametner
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    J Cereb Blood Flow Metab 35:1722-8. 2015
    ..032). Our findings suggest that bi-channel rSO2-NIRS has potential for guiding neuroanesthesia and predicting outcome. To better monitor local revascularization, an improved stroke-specific set-up in future studies is necessary. ..
  29. doi Options to restrict hematoma expansion after spontaneous intracerebral hemorrhage
    Thorsten Steiner
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 41:402-9. 2010
    ..The aim of this topical review is to give a summary of current evidence- and experience-based options to avoid or attenuate hematoma expansion...
  30. ncbi Severe Cerebral Venous and Sinus Thrombosis: Clinical Course, Imaging Correlates, and Prognosis
    Christina M Kowoll
    Department of Neurology, University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany
    Neurocrit Care 25:392-399. 2016
    ..Severe cerebral venous-sinus thrombosis (CVT) is a rare disease, and its clinical course, imaging correlates, as well as long-term prognosis have not yet been investigated systematically...
  31. doi Minimally invasive endoscopic surgery for treatment of spontaneous intracerebral hematomas: a single-center analysis
    Berk Orakcioglu
    Department of Neurosurgery, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Neurocrit Care 21:407-16. 2014
    ..However, most of these reports are based on Asian populations, while European reports do not exist. Here, we, therefore, report our experience from a European neurosurgical stroke center...
  32. ncbi Stereotactic biopsy and drainage of a brainstem abscess caused by Listeria monocytogenes
    Christopher Beynon
    Department of Neurosurgery, Heidelberg University Hospital, 69120 Heidelberg, Germany
    Neurol Med Chir (Tokyo) 53:263-5. 2013
    ..We successfully performed stereotactic biopsy and drainage of a listerial brainstem abscess in a 42-year-old male patient who deteriorated despite antibiotic treatment, demonstrating that this approach is suitable in such patients...
  33. doi Haemorrhage and hemicraniectomy: refining surgery for stroke
    Julian Bösel
    aDepartment of Neurology bDepartment of Neurosurgery, University of Heidelberg, Heidelberg, Germany
    Curr Opin Neurol 28:16-22. 2015
    ..Decompressive hemicraniectomy is effective in the treatment of space-occupying hemispheric ischaemic stroke. The purpose of this review is to assess the role of decompressive hemicraniectomy in intracerebral haemorrhage...
  34. doi Surgical aspects of decompression craniectomy in malignant stroke: review
    Klaus Zweckberger
    Department of Neurosurgery, University Heidelberg, Heidelberg, Germany
    Cerebrovasc Dis 38:313-23. 2014
    ....
  35. doi Administration of isoflurane-controlled dyskinetic movements caused by anti-NMDAR encephalitis
    Christoph Gumbinger
    From the Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Neurology 80:1997-8. 2013
    ..The present case report addresses the challenging management of these movement abnormalities with a volatile anesthetic in the prolonged period of intensive care treatment.(1,2.)..
  36. ncbi Delayed neurological deterioration in a stroke patient with postoperative acute anemia
    Julian Bösel
    Department of Neurology, Charite Campus Mitte, Humboldt University Berlin, Berlin, Germany
    Eur Neurol 53:36-8. 2005