G Anastassiou

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. pmc Prognostic value of clinical and histopathological parameters in conjunctival melanomas: a retrospective study
    Gerasimos Anastassiou
    Department of Ophthalmology, University Hospital Essen, University of Essen, Germany
    Br J Ophthalmol 86:163-7. 2002
  2. doi request reprint Transpalpebral electrotherapy for dry age-related macular degeneration (AMD): an exploratory trial
    Gerasimos Anastassiou
    Eye Hospital, D 45879 Gelsenkirchen, Germany
    Restor Neurol Neurosci 31:571-8. 2013
  3. pmc Ruthenium-106 plaque brachytherapy for symptomatic vasoproliferative tumours of the retina
    G Anastassiou
    Augenklinik, Universitatsklinikum Essen, 45122 Essen, Germany
    Br J Ophthalmol 90:447-50. 2006
  4. ncbi request reprint Expression of cell adhesion molecules and tumour infiltrating leucocytes in conjunctival melanoma
    Gerasimos Anastassiou
    Department of Ophthalmology, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Melanoma Res 14:381-5. 2004
  5. ncbi request reprint Expression of the cell adhesion molecules ICAM-1, VCAM-1 and NCAM in uveal melanoma: a clinicopathological study
    G Anastassiou
    Department of Ophthalmology, Biometry and Epidemiology, Medical Faculty, University of Essen, Germany
    Oncology 58:83-8. 2000
  6. ncbi request reprint Expression of classic and nonclassic HLA class I antigens in uveal melanoma
    Gerasimos Anastassiou
    Eye Clinic, University Clinic, Essen, Germany
    Invest Ophthalmol Vis Sci 44:2016-9. 2003
  7. ncbi request reprint [Prognostically relevant markers of malignant melanoma of the uvea]
    G Anastassiou
    Augenklinik, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen
    Ophthalmologe 99:327-32. 2002
  8. pmc Expression of VLA-2, VLA-3, and alpha(v) integrin receptors in uveal melanoma: association with microvascular architecture of the tumour and prognostic value
    G Anastassiou
    Department of Ophthalmology, Medical Faculty, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Br J Ophthalmol 84:899-902. 2000
  9. ncbi request reprint Expression of Fas and Fas ligand in uveal melanoma: biological implication and prognostic value
    G Anastassiou
    Department of Ophthalmology, University Hospital, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    J Pathol 194:466-72. 2001
  10. pmc Photodynamic therapy using verteporfin in circumscribed choroidal haemangioma
    B Jurklies
    Department of Ophthalmology, Univ Hospital Essen, Germany Department of Ophthalmology, Univ Hospital Lübeck, Germany
    Br J Ophthalmol 87:84-9. 2003

Collaborators

Detail Information

Publications32

  1. pmc Prognostic value of clinical and histopathological parameters in conjunctival melanomas: a retrospective study
    Gerasimos Anastassiou
    Department of Ophthalmology, University Hospital Essen, University of Essen, Germany
    Br J Ophthalmol 86:163-7. 2002
    ..To determine prognostic factors for recurrence of disease and tumour related mortality in patients with conjunctival melanoma...
  2. doi request reprint Transpalpebral electrotherapy for dry age-related macular degeneration (AMD): an exploratory trial
    Gerasimos Anastassiou
    Eye Hospital, D 45879 Gelsenkirchen, Germany
    Restor Neurol Neurosci 31:571-8. 2013
    ..To evaluate the effect of transpalpebral electrotherapy on patients with dry age-related macular degeneration (AMD)...
  3. pmc Ruthenium-106 plaque brachytherapy for symptomatic vasoproliferative tumours of the retina
    G Anastassiou
    Augenklinik, Universitatsklinikum Essen, 45122 Essen, Germany
    Br J Ophthalmol 90:447-50. 2006
    ..To investigate the safety and efficacy of beta ray brachytherapy in treatment of vasoproliferative tumours of the retina (VTR)...
  4. ncbi request reprint Expression of cell adhesion molecules and tumour infiltrating leucocytes in conjunctival melanoma
    Gerasimos Anastassiou
    Department of Ophthalmology, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Melanoma Res 14:381-5. 2004
    ..We investigated the expression of cell adhesion molecules and the grade of tumour infiltration with lymphocytes and macrophages as important members for the communication between tumour cells and the immune system...
  5. ncbi request reprint Expression of the cell adhesion molecules ICAM-1, VCAM-1 and NCAM in uveal melanoma: a clinicopathological study
    G Anastassiou
    Department of Ophthalmology, Biometry and Epidemiology, Medical Faculty, University of Essen, Germany
    Oncology 58:83-8. 2000
    ..NCAM and VCAM-1 expression was not related to metastasis. Our results show that the loss of ICAM-1 expression is associated with an increased risk of metastasis within the first 5 years after diagnosis...
  6. ncbi request reprint Expression of classic and nonclassic HLA class I antigens in uveal melanoma
    Gerasimos Anastassiou
    Eye Clinic, University Clinic, Essen, Germany
    Invest Ophthalmol Vis Sci 44:2016-9. 2003
    ....
  7. ncbi request reprint [Prognostically relevant markers of malignant melanoma of the uvea]
    G Anastassiou
    Augenklinik, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen
    Ophthalmologe 99:327-32. 2002
    ..In particular, with the aid of new technologies such as microarray analysis, researchers around the globe hope that new and exciting discoveries will be made that can also modify therapy concepts...
  8. pmc Expression of VLA-2, VLA-3, and alpha(v) integrin receptors in uveal melanoma: association with microvascular architecture of the tumour and prognostic value
    G Anastassiou
    Department of Ophthalmology, Medical Faculty, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Br J Ophthalmol 84:899-902. 2000
    ..There is some evidence that interactions between the tumour cells and the extracellular matrix are responsible for the shape of these patterns...
  9. ncbi request reprint Expression of Fas and Fas ligand in uveal melanoma: biological implication and prognostic value
    G Anastassiou
    Department of Ophthalmology, University Hospital, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    J Pathol 194:466-72. 2001
    ..The clinical relevance of this observation is limited, as more predictive parameters have been described for uveal melanoma...
  10. pmc Photodynamic therapy using verteporfin in circumscribed choroidal haemangioma
    B Jurklies
    Department of Ophthalmology, Univ Hospital Essen, Germany Department of Ophthalmology, Univ Hospital Lübeck, Germany
    Br J Ophthalmol 87:84-9. 2003
    ..To investigate the safety and efficacy of photodynamic therapy with verteporfin in patients with choroidal haemangioma...
  11. ncbi request reprint [Analysis of ocular surface alterations following proton beam radiation in eyes with conjunctival malignant melanoma]
    H Westekemper
    Zentrum für Augenheilkunde, Universitatsklinikum, Hufelandstrasse 55, 45122 Essen
    Ophthalmologe 103:588-95. 2006
    ..In extended tumours, ocular surface problems can result after therapy. In this study we examined ocular surface integrity of ten patients who underwent proton beam radiation between 1996 and 2002...
  12. ncbi request reprint Partial deletions of the long and short arm of chromosome 3 point to two tumor suppressor genes in uveal melanoma
    F Tschentscher
    Institut fur Humangenetik, Universitatsklinikum Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Cancer Res 61:3439-42. 2001
    ..5 Mb in 3p25. This SRO does not overlap with the VHL gene. Our finding suggests a role for two tumor suppressor genes in metastasizing uveal melanoma and may explain the loss of an entire chromosome 3 in these tumors...
  13. ncbi request reprint The possible role of radiofrequency radiation in the development of uveal melanoma
    A Stang
    Institute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Essen, Germany
    Epidemiology 12:7-12. 2001
    ..This is the first study describing an association between radiofrequency radiation exposure and uveal melanoma. Several methodologic limitations prevent our results from providing clear evidence on the hypothesized association...
  14. ncbi request reprint [Endoscopic resection of malignant melanomas of the uvea after preoperative stereotactic single dose convergence irradiation with the Leksell gamma knife]
    N Bornfeld
    Universitatsklinikum Essen, Zentrum für Augenheilkunde, Abteilung für Erkrankungen des hinteren Augenabschnitts, Hufelandstrasse 55, 45122 Essen
    Ophthalmologe 99:338-44. 2002
    ..Tumor-destroying, single-dose convergence irradiation (radiosurgery) of such tumors applied shortly before endoresection can represent a possible therapeutic alternative in these types of cases...
  15. ncbi request reprint [Endoresection of large uveal melanomas after pretreatment by single-dose stereotactic convergence irradiation with the leksell gamma knife--first experience on 46 cases]
    H Schilling
    Universitäts Augenklinik Essen
    Klin Monbl Augenheilkd 223:513-20. 2006
    ..The aim of this non-comparative, consecutive case series is to evaluate the short-term results after endoresection of large uveal melanomas in combination with pretreatment with stereotactic gamma knife radiosurgery...
  16. ncbi request reprint Proton radiotherapy as an alternative to exenteration in the management of extended conjunctival melanoma
    Henrike Wuestemeyer
    Department of Ophthalmology, University of Essen, Hufelandstr 52, 45122, Essen, Germany
    Graefes Arch Clin Exp Ophthalmol 244:438-46. 2006
    ..Diffuse and multifocal patterns of conjunctival melanoma may not be treatable with standard eye-sparing methods. The purpose of this study was to evaluate the usefulness of proton beam radiation therapy as an alternative to exenteration...
  17. ncbi request reprint Loss of heterozygosity of 1p in uveal melanomas with monosomy 3
    Thomas Häusler
    Institut fur Humangenetik, Universitatsklinikum Essen, Essen, Germany
    Int J Cancer 116:909-13. 2005
    ..On the basis of our data and published cytogenetic data, we propose that 1p31 harbors genes involved in the progression of uveal melanoma with monosomy 3...
  18. ncbi request reprint De novo intraocular retinoblastoma development after chemotherapy in patients with hereditary retinoblastoma
    Andreas O Schueler
    Department of Ophthalmology, Universitatsklinikum Essen, Augenklinik, Hufelandstrasse 55, 45122 Essen, Germany
    Retina 26:425-31. 2006
    ..Identification of incidence and risk factors for recurrence of de novo retinoblastomas after chemotherapy treatment in patients with hereditary retinoblastoma...
  19. ncbi request reprint Differential expression of tissue inhibitor of matrix metalloproteinases 3 in uveal melanoma
    Gordon Nareyeck
    Department of Ophthalmology, Universitatsklinikum Essen, Essen, Germany
    Ophthalmic Res 37:23-8. 2005
    ..There was a trend between TIMP-3 protein expression and both cell type (p = 0.11) and presence of loops and/or networks (p = 0.06) in tumour which may indicate a role of TIMP-3 in the biology of uveal melanoma...
  20. ncbi request reprint The design and the dosimetry of bi-nuclide radioactive ophthalmic applicators
    Dirk Flühs
    University Hospital Essen, Department of Radiotherapy, Hufelandstr 55, D 45122 Essen, Germany
    Med Phys 31:1481-8. 2004
    ..The precondition was the availability, developed in recent years, of a more accurate determination of the absolute dose rate to water of beta- and low energy emitters...
  21. ncbi request reprint Evaluation of vitrectomy specimens and chorioretinal biopsies in the diagnosis of primary intraocular lymphoma in patients with Masquerade syndrome
    Sarah E Coupland
    Department of Pathology, University Hospital Benjamin Franklin, Free University, Hindenburgdamm 30, 12200 Berlin, Germany
    Graefes Arch Clin Exp Ophthalmol 241:860-70. 2003
    ....
  22. ncbi request reprint Phenotypical characteristics, lifestyle, social class and uveal melanoma
    Andreas Stang
    Institute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Essen, Germany
    Ophthalmic Epidemiol 10:293-302. 2003
    ..To investigate potential risk factors of uveal melanoma, including phenotypical characteristics, eye burns, social class, smoking and alcohol consumption...
  23. ncbi request reprint Tumor classification based on gene expression profiling shows that uveal melanomas with and without monosomy 3 represent two distinct entities
    Frank Tschentscher
    Institut fur Humangenetik, Universitatsklinikum Essen, 45122 Essen, Germany
    Cancer Res 63:2578-84. 2003
    ..Our findings suggest that there are two distinct entities of uveal melanoma that were previously unrecognized because they are not obviously distinguishable by clinicopathological features...
  24. ncbi request reprint Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3
    Gordon Nareyeck
    Department of Ophthalmology, University of Duisburg Essen, Augenklinik, Universitaetsklinikum Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Exp Eye Res 83:858-64. 2006
    ..Our data suggest that, UPMM-1 may serve as a model system to study the mechanisms underlying the metastatic potential of uveal melanomas with monosomy 3...
  25. ncbi request reprint Occupation as a risk factor for uveal melanoma in Germany
    Joel Monárrez-Espino
    Institute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Essen, Germany
    Scand J Work Environ Health 28:270-7. 2002
    ..This study explored occupational risks linked to uveal melanoma...
  26. ncbi request reprint Beta-ray brachytherapy of retinoblastoma: feasibility of a new small-sized ruthenium-106 plaque
    Andreas O Schueler
    Department of Ophthalmology, Universitatsklinikum Essen, Germany
    Ophthalmic Res 38:8-12. 2006
    ..A non-comparative case observation study estimated the feasibility of brachytherapy for retinoblastoma with a newly designed ruthenium-106 plaque (label: CXS) with an 8-mm diameter of the irradiation zone...
  27. ncbi request reprint Establishment of two cell lines derived from conjunctival melanomas
    Gordon Nareyeck
    Exp Eye Res 81:361-2. 2005
  28. ncbi request reprint Primary intraocular lymphoma of T-cell type: report of a case and review of the literature
    Sarah E Coupland
    Department of Pathology, Charite Medical Faculty Berlin, Campus Benjamin Franklin, Germany
    Graefes Arch Clin Exp Ophthalmol 243:189-97. 2005
    ..The aim of the current paper is to report the clinical, histopathological and molecular biological findings of a PIOL of T-cell type...
  29. ncbi request reprint Diagnosis of a primary uveal extranodal marginal zone B-cell lymphoma by chorioretinal biopsy: case report
    Sarah E Coupland
    Department of Pathology, Charite University Hospital, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Graefes Arch Clin Exp Ophthalmol 243:482-6. 2005
    ..To report the clinical, histopathological and molecular biological findings of a primary extranodal marginal zone B-cell lymphoma (EMZL) of the uvea...
  30. ncbi request reprint Quality of life in patients with malignant choroidal melanoma after radiotherapy
    Jens Reimer
    Department of Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany
    Graefes Arch Clin Exp Ophthalmol 241:371-7. 2003
    ....
  31. ncbi request reprint Cadherin expression in uveal melanoma
    Gerasimos Anastassiou
    Exp Eye Res 74:423-5. 2002
  32. ncbi request reprint Assessment of genomic instability in breast cancer and uveal melanoma by random amplified polymorphic DNA analysis
    Sarantos Papadopoulos
    Department of Obstetrics and Gynecology, Free University of Berlin, Berlin, Germany
    Int J Cancer 99:193-200. 2002
    ..Our study confirms other reports that the molecular karyotypes produced with random priming, called amplotypes, are very useful for assessing genomic damage in cancer...