Jens Titze

Summary

Country: Germany

Publications

  1. ncbi request reprint Bone mineral content and blood pressure: What is the pathophysiologic link?
    Jens Titze
    Department of Nephrology and Hypertension, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Am J Hypertens 19:877-8. 2006
  2. ncbi request reprint Long-term sodium balance in humans in a terrestrial space station simulation study
    Jens Titze
    Department of Physiology, Free University of Berlin, Germany
    Am J Kidney Dis 40:508-16. 2002
  3. ncbi request reprint Diarrhea, nephrotic syndrome and hidradenitis suppurativa: an unusual case
    Jens Titze
    Department of Nephrology, Friedrich Alexander University Erlangen Nurnberg, Nurnberg, Germany
    Nephrol Dial Transplant 18:192-4. 2003
  4. ncbi request reprint Osmotically inactive skin Na+ storage in rats
    Jens Titze
    Department of Nephrology, Friedrich Alexander University Erlangen Nuremberg, Loschgestrasse 8, D 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 285:F1108-17. 2003
  5. ncbi request reprint Glycosaminoglycan polymerization may enable osmotically inactive Na+ storage in the skin
    Jens Titze
    Department of Medicine IV, Friedrich Alexander University Erlangen Nurnberg, Germany
    Am J Physiol Heart Circ Physiol 287:H203-8. 2004
  6. ncbi request reprint Hypertension, sodium retention, calcium excretion and osteopenia in Dahl rats
    Jens Titze
    Department of Medicine IV, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    J Hypertens 22:803-10. 2004
  7. doi request reprint Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats
    Agnes Machnik
    Department of Nephrology and Hypertension, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Hypertension 55:755-61. 2010
  8. ncbi request reprint Mobilization of osmotically inactive Na+ by growth and by dietary salt restriction in rats
    Markus Schafflhuber
    Department of Nephrology and Hypertension, Friedrich Alexander University, Erlangen, Nurnberg, Germany
    Am J Physiol Renal Physiol 292:F1490-500. 2007
  9. doi request reprint Sodium-, potassium-, chloride-, and bicarbonate-related effects on blood pressure and electrolyte homeostasis in deoxycorticosterone acetate-treated rats
    Agata Ziomber
    Department of Nephrology and Hypertension, Nikolaus Fiebiger Center for Molecular Medicine, Glückstr 6, 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 295:F1752-63. 2008
  10. ncbi request reprint Reduced osmotically inactive Na storage capacity and hypertension in the Dahl model
    Jens Titze
    Department of Nephrology, Friedrich Alexander University Erlangen Nurnberg, D 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 283:F134-41. 2002

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Bone mineral content and blood pressure: What is the pathophysiologic link?
    Jens Titze
    Department of Nephrology and Hypertension, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Am J Hypertens 19:877-8. 2006
  2. ncbi request reprint Long-term sodium balance in humans in a terrestrial space station simulation study
    Jens Titze
    Department of Physiology, Free University of Berlin, Germany
    Am J Kidney Dis 40:508-16. 2002
    ..We investigated sodium balance and its impact on body weight (BW) during a long-term balance study...
  3. ncbi request reprint Diarrhea, nephrotic syndrome and hidradenitis suppurativa: an unusual case
    Jens Titze
    Department of Nephrology, Friedrich Alexander University Erlangen Nurnberg, Nurnberg, Germany
    Nephrol Dial Transplant 18:192-4. 2003
  4. ncbi request reprint Osmotically inactive skin Na+ storage in rats
    Jens Titze
    Department of Nephrology, Friedrich Alexander University Erlangen Nuremberg, Loschgestrasse 8, D 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 285:F1108-17. 2003
    ..OVX leads to an acquired reduction of osmotically inactive Na+ storage in SD rats that predisposes the rats to volume excess despite a reduced Na+ content relative to body weight...
  5. ncbi request reprint Glycosaminoglycan polymerization may enable osmotically inactive Na+ storage in the skin
    Jens Titze
    Department of Medicine IV, Friedrich Alexander University Erlangen Nurnberg, Germany
    Am J Physiol Heart Circ Physiol 287:H203-8. 2004
    ..Inhibition or disinhibition of GAG chain polymerization may regulate osmotically inactive Na(+) storage...
  6. ncbi request reprint Hypertension, sodium retention, calcium excretion and osteopenia in Dahl rats
    Jens Titze
    Department of Medicine IV, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    J Hypertens 22:803-10. 2004
    ..Salt-sensitive hypertension in the Dahl rat is associated with abnormalities in both calcium (Ca2+) and sodium (Na) homeostasis...
  7. doi request reprint Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats
    Agnes Machnik
    Department of Nephrology and Hypertension, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Hypertension 55:755-61. 2010
    ..Failure of this physiological extrarenal regulatory mechanism leads to a salt-sensitive blood pressure response...
  8. ncbi request reprint Mobilization of osmotically inactive Na+ by growth and by dietary salt restriction in rats
    Markus Schafflhuber
    Department of Nephrology and Hypertension, Friedrich Alexander University, Erlangen, Nurnberg, Germany
    Am J Physiol Renal Physiol 292:F1490-500. 2007
    ....
  9. doi request reprint Sodium-, potassium-, chloride-, and bicarbonate-related effects on blood pressure and electrolyte homeostasis in deoxycorticosterone acetate-treated rats
    Agata Ziomber
    Department of Nephrology and Hypertension, Nikolaus Fiebiger Center for Molecular Medicine, Glückstr 6, 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 295:F1752-63. 2008
    ..We conclude that excessive cellular electrolyte redistribution and/or intracellular Na(+) or Cl(-) accumulation may play an important role in the pathogenesis of salt-sensitive hypertension...
  10. ncbi request reprint Reduced osmotically inactive Na storage capacity and hypertension in the Dahl model
    Jens Titze
    Department of Nephrology, Friedrich Alexander University Erlangen Nurnberg, D 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 283:F134-41. 2002
    ..Additional factors, including impaired renal Na excretion, probably contribute to hypertension in SS rats. Our results draw attention to the role of osmotically inactive Na storage...
  11. ncbi request reprint Extrarenal Na+ balance, volume, and blood pressure homeostasis in intact and ovariectomized deoxycorticosterone-acetate salt rats
    Jens Titze
    Department of Nephrology and Hypertension, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Hypertension 47:1101-7. 2006
    ..Extrarenal Na+ and volume balance seem to play an important role in long-term volume and MAP control...
  12. pmc Quantitative assessment of muscle injury by (23)Na magnetic resonance imaging
    Anke Dahlmann
    Department of Nephrology and Hypertension, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Springerplus 5:661. 2016
    ..We now tested the utility of (23)Na-MRI technique in detecting and assessing sports-related acute muscular injury...
  13. doi request reprint Skin sodium measured with ²³Na MRI at 7.0 T
    Peter Linz
    Interdisciplinary Center for Clinical Research, Nikolaus Fiebiger Center for Molecular Medicine, Friedrich Alexander University Erlangen Nurnberg, Germany
    NMR Biomed 28:54-62. 2015
    ..0 T technology. The benefits of such improvements may have the potential to aid basic research and clinical applications designed to unlock questions regarding the Na(+) balance and Na(+) storage function of skin...
  14. doi request reprint Long-term space flight simulation reveals infradian rhythmicity in human Na(+) balance
    Natalia Rakova
    Interdisciplinary Center for Clinical Research, Friedrich Alexander University, Erlangen Nurnberg, Glückstrasse 6, D 91054 Erlangen, Germany
    Cell Metab 17:125-31. 2013
    ..Our findings define rhythmic Na(+) excretory and retention patterns independent of blood pressure or body water, which occur independent of salt intake...
  15. doi request reprint (23)Na magnetic resonance imaging of tissue sodium
    Christoph Kopp
    Department of Nephrology and Hypertension, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Hypertension 59:167-72. 2012
    ..We suggest that, after further refinements, this tool could facilitate understanding the relationships between Na(+) accumulation and hypertension. Furthermore, with additional technical advances, a future clinical use may be possible...
  16. doi request reprint Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism
    Agnes Machnik
    Department of Nephrology and Hypertension, and Nikolaus Fiebiger Centre for Molecular Medicine, University Clinic and Friedrich Alexander University of Erlangen Nuremberg, Germany
    Nat Med 15:545-52. 2009
    ....
  17. doi request reprint Water-free sodium accumulation
    Jens Titze
    Department of Nephrology and Hypertension, Friedrich Alexander University, Glückstrasse 6, Erlangen Nurnberg, Germany
    Semin Dial 22:253-5. 2009
    ..Besides the control of the body Na(+) content by the kidneys, redistribution of body electrolytes hence provides an extrarenal regulatory alternative in the maintenance of body fluid volume and blood pressure control...
  18. ncbi request reprint Salt and its effect on blood pressure and target organ damage: new pieces in an old puzzle
    Jens Titze
    Department of Nephrology and Hypertension, University of Erlangen, Erlangen, Germany
    J Nephrol 22:177-89. 2009
    ..Furthermore, salt promotes the secretion of cardiotonic steroids, i.e., mammalian "digitalis." Initial observations suggest a causal role for cardiotonic steroids in the genesis of cardiac abnormalities in advanced renal disease...
  19. pmc 23Na Magnetic Resonance Imaging of the Lower Leg of Acute Heart Failure Patients during Diuretic Treatment
    Matthias Hammon
    Department of Radiology, University Hospital Erlangen, Erlangen, Germany
    PLoS ONE 10:e0141336. 2015
    ..The aim of this study was to assess Na+ and H2O in muscle and skin with MRI in acute heart failure patients before and after diuretic treatment and in a healthy cohort...
  20. doi request reprint Interstitial fluid homeostasis and pressure: news from the black box
    Jens Titze
    1 Division of Clinical Pharmacology, Vanderbilt University, Nashville, Tennessee, USA 2 Junior Research Group 2, Interdisciplinary Center for Clinical Research and Department of Nephrology and Hypertension, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Kidney Int 84:869-71. 2013
    ..In this issue, Ebah and colleagues demonstrate a direct relationship between fluid overload and pressure in CKD patients. Surprise, instead of intravascular volume, interstitial fluids and pressures were measured. Finally! ..
  21. doi request reprint Cardiovascular and renal effects of high salt diet in GDNF+/- mice with low nephron number
    Julia Schlote
    Department of Pathology, IZKF Nachwuchsgruppe, Department of Nephrology and Hypertension, Department of Pediatrics, University of Erlangen Nurnberg, Germany
    Kidney Blood Press Res 37:379-91. 2013
    ..To test the suggested association of low nephron number and later development of renal and cardiovascular disease we investigated the effects of high sodium diet in heterozygous GDNF+/- mice...
  22. doi request reprint Water-free Na+ retention: interaction with hypertension and tissue hydration
    Jens Titze
    Department of Nephrology and Hypertension and Nikolaus Fiebiger Center for Molecular Medicine, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Blood Purif 26:95-9. 2008
    ..Besides the control of the body Na(+) content by the kidneys, redistribution of body electrolytes hence provides an extrarenal regulatory alternative in the maintenance of body fluid volume and blood pressure control...
  23. ncbi request reprint Internal sodium balance in DOCA-salt rats: a body composition study
    Jens Titze
    Forschungslabor der Medizinischen Klinik IV, Kreuzburger Strasse 2, 90471 Nürnberg, Germany
    Am J Physiol Renal Physiol 289:F793-802. 2005
    ..This "internal Na(+) escape" allows the maintenance of volume homeostasis despite increased total body Na(+)...
  24. ncbi request reprint Simultaneous detection of submicrogram quantities of hyaluronic acid and dermatan sulfate on agarose-gel by sequential staining with toluidine blue and Stains-All
    Nicola Volpi
    Department of Biologia Animale, University of Modena and Reggio Emilia, Via Campi 213 D, 41100 Modena, Italy
    J Chromatogr B Analyt Technol Biomed Life Sci 820:131-5. 2005
    ....
  25. doi request reprint Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension
    Petra Gratze
    Medical Faculty of the Charite, Experimental and Clinical Research Center, Franz Volhard Clinic, Berlin, Germany
    Circulation 117:2645-56. 2008
    ..We tested the hypothesis that an alteration in the number and quality of circulating blood cells caused by Id2 deletion would ameliorate Ang II-induced target-organ damage...