F Tergau

Summary

Country: Germany

Publications

  1. ncbi Can epilepsies be improved by repetitive transcranial magnetic stimulation?--interim analysis of a controlled study
    Frithjof Tergau
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Strasse 40, D 37075 Gottingen, Germany
    Suppl Clin Neurophysiol 56:400-5. 2003
  2. ncbi Motor cortex fatigue in sports measured by transcranial magnetic double stimulation
    F Tergau
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Med Sci Sports Exerc 32:1942-8. 2000
  3. ncbi Relationship between lamotrigine oral dose, serum level and its inhibitory effect on CNS: insights from transcranial magnetic stimulation
    Frithjof Tergau
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Strasse 40, D 37075 Goettingen, Germany
    Epilepsy Res 56:67-77. 2003
  4. ncbi Complete suppression of voluntary motor drive during the silent period after transcranial magnetic stimulation
    F Tergau
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Exp Brain Res 124:447-54. 1999
  5. pmc Demonstration of facilitatory I wave interaction in the human motor cortex by paired transcranial magnetic stimulation
    U Ziemann
    Department of Clinical Neurophysiology, University of Gottingen, Human Motor Control Section, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Physiol 511:181-90. 1998
  6. ncbi Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study
    U Ziemann
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Electroencephalogr Clin Neurophysiol 109:321-30. 1998
  7. ncbi Piracetam affects facilitatory I-wave interaction in the human motor cortex
    S Wischer
    Department of Clinical Neurophysiology, University of Goettingen, Robert-Koch-Strasse 40, D-37075, Goettingen, Germany
    Clin Neurophysiol 112:275-9. 2001
  8. ncbi Changes in human motor cortex excitability induced by dopaminergic and anti-dopaminergic drugs
    U Ziemann
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Electroencephalogr Clin Neurophysiol 105:430-7. 1997
  9. pmc Voluntary motor drive: possible reduction in Tourette syndrome
    C A Heise
    Child and Adolescent Psychiatry, University of Gottingen, Gottingen, Germany
    J Neural Transm (Vienna) 115:857-61. 2008
  10. ncbi Paired-pulse repetitive transcranial magnetic stimulation of the human motor cortex
    M Sommer
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Exp Brain Res 139:465-72. 2001

Detail Information

Publications41

  1. ncbi Can epilepsies be improved by repetitive transcranial magnetic stimulation?--interim analysis of a controlled study
    Frithjof Tergau
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Strasse 40, D 37075 Gottingen, Germany
    Suppl Clin Neurophysiol 56:400-5. 2003
  2. ncbi Motor cortex fatigue in sports measured by transcranial magnetic double stimulation
    F Tergau
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Med Sci Sports Exerc 32:1942-8. 2000
    ..The mechanisms responsible are still in discussion. Using noninvasive transcranial magnetic stimulation (TMS) in a double-pulse technique, we sought to assess fatigue of the motor cortex after exhaustive anaerobic strain...
  3. ncbi Relationship between lamotrigine oral dose, serum level and its inhibitory effect on CNS: insights from transcranial magnetic stimulation
    Frithjof Tergau
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Strasse 40, D 37075 Goettingen, Germany
    Epilepsy Res 56:67-77. 2003
    ....
  4. ncbi Complete suppression of voluntary motor drive during the silent period after transcranial magnetic stimulation
    F Tergau
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Exp Brain Res 124:447-54. 1999
    ..It is argued that the pathway of fast cortico-spinal fibers activated by TMS is partially different from the pathway involved in the maintenance of tonic voluntary muscle activation...
  5. pmc Demonstration of facilitatory I wave interaction in the human motor cortex by paired transcranial magnetic stimulation
    U Ziemann
    Department of Clinical Neurophysiology, University of Gottingen, Human Motor Control Section, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Physiol 511:181-90. 1998
    ..5. It is concluded that the MEP facilitation after paired TMS, at least for the first MEP peak, is due to facilitatory interaction between I waves, and takes place in the motor cortex at or upstream from the corticospinal neurone...
  6. ncbi Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study
    U Ziemann
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Electroencephalogr Clin Neurophysiol 109:321-30. 1998
    ..The potential relevance of this non-invasive paired TMS protocol for the investigation of I-waves in patients with neurological disease will be discussed...
  7. ncbi Piracetam affects facilitatory I-wave interaction in the human motor cortex
    S Wischer
    Department of Clinical Neurophysiology, University of Goettingen, Robert-Koch-Strasse 40, D-37075, Goettingen, Germany
    Clin Neurophysiol 112:275-9. 2001
    ..Shortening of the I-wave peak latencies is a new phenomenon. The results are discussed on the basis of the known therapeutic effects of piracetam in cortical myoclonus and as nootropic agent...
  8. ncbi Changes in human motor cortex excitability induced by dopaminergic and anti-dopaminergic drugs
    U Ziemann
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Electroencephalogr Clin Neurophysiol 105:430-7. 1997
    ..The relation of the present findings to current models of motor excitability abnormalities in movement disorders will be discussed...
  9. pmc Voluntary motor drive: possible reduction in Tourette syndrome
    C A Heise
    Child and Adolescent Psychiatry, University of Gottingen, Gottingen, Germany
    J Neural Transm (Vienna) 115:857-61. 2008
    ..The findings support the notion, that TS shows possible reduction of VMD and is associated with central motor threshold alterations confined to the very motor networks related to the tics observed...
  10. ncbi Paired-pulse repetitive transcranial magnetic stimulation of the human motor cortex
    M Sommer
    Department of Clinical Neurophysiology, University of Gottingen, Germany
    Exp Brain Res 139:465-72. 2001
    ..In addition, our data suggest that short trains of paired-pulse rTMS are not superior to single-pulse rTMS in inducing lasting inhibition or facilitation...
  11. pmc Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans
    M A Nitsche
    Department of Clinical Neurophysiology, Georg August University, Goettingen, Germany
    J Physiol 553:293-301. 2003
    ..The selective elimination of tDCS-driven excitability enhancements by carbamazepine proposes a role for this drug in focussing the effects of cathodal tDCS, which may have important future clinical applications...
  12. ncbi Delay in simple reaction time after focal transcranial magnetic stimulation of the human brain occurs at the final motor output stage
    U Ziemann
    Department of Clinical Neurophysiology, Georg August University of Gttingen, Germany
    Brain Res 744:32-40. 1997
    ....
  13. ncbi Intra- and interindividual variability of motor responses to repetitive transcranial magnetic stimulation
    M Sommer
    Department of Clinical Neurophysiology, University of Goettingen, P O Box 3742, D 37070, Goettingen, Germany
    Clin Neurophysiol 113:265-9. 2002
    ..We sought to determine the intra- and interindividual variability of its effects on motor cortex excitability, and whether repeated paired-pulses yield less variability than repeated single-pulses...
  14. ncbi GABAergic modulation of DC stimulation-induced motor cortex excitability shifts in humans
    Michael A Nitsche
    Department of Clinical Neurophysiology, University of Goettingen, Robert Koch Str 40, 37075 Goettingen, Germany
    Eur J Neurosci 19:2720-6. 2004
    ..Because intracortical inhibition and facilitation are not changed in this phase compared with pre-tDCS values, excitability changes originating from remote cortical or subcortical areas could be involved...
  15. ncbi Pregabalin exerts oppositional effects on different inhibitory circuits in human motor cortex: a double-blind, placebo-controlled transcranial magnetic stimulation study
    Nicolas Lang
    Department of Clinical Neurophysiology, Georg August University, Goettingen, Germany
    Epilepsia 47:813-9. 2006
    ..To explore acute effects of pregabalin (PGB) on human motor cortex excitability with transcranial magnetic stimulation (TMS)...
  16. ncbi Normal intracortical excitability in developmental stuttering
    Martin Sommer
    Department of Clinical Neurophysiology, University of Gottingen, Gottingen, Germany
    Mov Disord 18:826-30. 2003
    ..Normal intracortical excitability makes a pathophysiological analogy between focal dystonia and PDS less likely. The enhanced motor threshold suggests reduced motor cortical neuronal membrane excitability in PDS...
  17. doi H-coil: Induced electric field properties and input/output curves on healthy volunteers, comparison with a standard figure-of-eight coil
    Tommaso Fadini
    Department of Clinical Neurophysiology, University of Goettingen, Robert Koch Str 40, 37075 Goettingen, Germany
    Clin Neurophysiol 120:1174-82. 2009
    ..To acquire information about the physical properties and physiological effects of the H-coil...
  18. ncbi Level of action of cathodal DC polarisation induced inhibition of the human motor cortex
    Michael A Nitsche
    Department of Clinical Neurophysiology, University of Goettingen, Robert Koch Str 40, 37075, Goettingen, Germany
    Clin Neurophysiol 114:600-4. 2003
    ..To induce prolonged motor cortical excitability reductions by transcranial direct current stimulation in the human...
  19. ncbi Orientation-specific fast rTMS maximizes corticospinal inhibition and facilitation
    Tobias Tings
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Str 40, 37075, Gottingen, Germany
    Exp Brain Res 164:323-33. 2005
    ..In any case biphasic rTMS results can be explained by a mixture of monophasic opposite stimulations. We propose the use of monophasic pulses for maximizing effects during rTMS...
  20. doi Limited impact of homeostatic plasticity on motor learning in humans
    Min Fang Kuo
    Department of Clinical Neurophysiology, University of Goettingen, Robert Koch Str 40, 37099 Goettingen, Germany
    Neuropsychologia 46:2122-8. 2008
    ..We conclude that homeostatic plasticity, as tested here, has a limited influence on implicit sequential motor learning...
  21. ncbi Bilateral changes in cortical motor representation of the tongue after unilateral peripheral facial paralysis: evidence from transcranial magnetic stimulation
    Ralph M W Rödel
    Department of Otorhinolaryngology, University of Gottingen, Gottingen, Germany
    Ann Otol Rhinol Laryngol 113:951-5. 2004
    ..Thus, we provide strong evidence of bilateral changes in lingual cortical motor representation following facial paralysis with an invasion of the facial motor area by the tongue motor representation...
  22. ncbi Inverse correlation of intracortical inhibition and brain-stem inhibition in humans
    Martin Sommer
    Department of Clinical Neurology, University of Gottingen, Robert Koch Strasse 40, D 37075 Gottingen, Germany
    Clin Neurophysiol 113:120-3. 2002
    ..To determine whether intracortical inhibition and the conditioned blink reflex R2 inhibition correlate in healthy subjects...
  23. ncbi Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability
    David Liebetanz
    Department of Clinical Neurophysiology, Georg August University Goettingen, Robert Koch Strasse 40, 37075 Goettingen, Germany
    Brain 125:2238-47. 2002
    ....
  24. ncbi Modulation of motor consolidation by external DC stimulation
    Nicolas Lang
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Strasse 40, D 37075 Gottingen, Germany
    Suppl Clin Neurophysiol 56:277-81. 2003
  25. ncbi Treatment of restless legs syndrome with the dopamine agonist alpha-dihydroergocryptine
    F Tergau
    Department of Clinical Neurophysiology, Georg August University Gottingen, Germany
    Mov Disord 16:731-5. 2001
    ..Five patients needed domperidone for treatment of concomitant nausea. One patient stopped the study due to nausea. In conclusion, the results of this open study suggest a role for DHEC in the treatment of RLS...
  26. ncbi A case of cerebral Whipple's disease initially presenting with isolated focal myoclonus
    S Henning
    Department of Clinical Neurophysiology, Georg August University, Gottingen, Germany
    Eur J Neurol 13:659-61. 2006
    ..Additionally, we present - to our knowledge - a novel treatment by administration of immunomodulatory therapy (IVIg) in addition to established antibiotics...
  27. ncbi Catecholaminergic consolidation of motor cortical neuroplasticity in humans
    Michael A Nitsche
    Department of Clinical Neurophysiology, Georg August University, Robert Koch Str 40, 37075 Goettingen, Germany
    Cereb Cortex 14:1240-5. 2004
    ..This result may enable researchers to optimize neuroplastic processes in the human brain on the rational basis of purpose-designed pharmacological interventions...
  28. ncbi Anticonvulsant effects of transcranial direct-current stimulation (tDCS) in the rat cortical ramp model of focal epilepsy
    David Liebetanz
    Department of Clinical Neurophysiology, Georg August University, Gottingen, Germany
    Epilepsia 47:1216-24. 2006
    ..To evaluate its anticonvulsant potential, transcranial direct current stimulation (tDCS) was tested in a modified cortical ramp-stimulation model of focal epilepsy...
  29. ncbi Neuronal tissue polarization induced by repetitive transcranial magnetic stimulation?
    Martin Sommer
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Str 40, 37075 Gottingen, Germany
    Neuroreport 13:809-11. 2002
    ..d.). We propose that the current flow in the coil plays a significant role in optimising after effects, and asymmetric current flow may be particularly efficient in building up tissue polarization...
  30. ncbi Facilitation of implicit motor learning by weak transcranial direct current stimulation of the primary motor cortex in the human
    Michael A Nitsche
    Department of Clinical Neurophysiology, University of Goettingen, Goettingen, Germany
    J Cogn Neurosci 15:619-26. 2003
    ..We conclude that the primary motor cortex is involved in the acquisition and early consolidation phase of implicit motor learning...
  31. ncbi Repetitive paired-pulse transcranial magnetic stimulation affects corticospinal excitability and finger tapping in Parkinson's disease
    Martin Sommer
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Str 40, Gottingen, Germany
    Clin Neurophysiol 113:944-50. 2002
    ..To study the effect of long trains of a recently established conditioning-test paired-pulse repetitive transcranial magnetic stimulation (rTMS) paradigm on corticospinal excitability and finger tapping speed...
  32. pmc Modulating parameters of excitability during and after transcranial direct current stimulation of the human motor cortex
    Michael A Nitsche
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Str 40, 37075 Gottingen, Germany
    J Physiol 568:291-303. 2005
    ..In contrast, the after-effects of tDCS are due to shifts in intracortical inhibition and facilitation, and at least partly also to facilitatory I-wave interaction, which is controlled by synaptic activity...
  33. ncbi Modulation of cortical excitability by weak direct current stimulation--technical, safety and functional aspects
    Michael A Nitsche
    Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Strasse 40, D 37075 Gotingen, Germany
    Suppl Clin Neurophysiol 56:255-76. 2003
  34. ncbi Intracortical excitability in the hand motor representation in hand dystonia and blepharospasm
    Martin Sommer
    Department of Clinical Neurophysiology, University of Gottingen, Gottingen, Germany
    Mov Disord 17:1017-25. 2002
    ..In addition, our findings in both patient groups show a trend toward a relatively increased intracortical facilitation in surrounding motor areas...
  35. ncbi Levetiracetam influences human motor cortex excitability mainly by modulation of ion channel function--a TMS study
    Janine Reis
    Interdisciplinary Epilepsy Center, Department of Neurology, Philipps University, 35033 Marburg, Germany
    Epilepsy Res 62:41-51. 2004
    ..Levetiracetam (LEV) is a new compound with anticonvulsive efficacy in focal and generalized epilepsies. Recent in vitro studies suggest LEV to act as a selective N-type-calcium-channel blocker...
  36. ncbi Topiramate selectively decreases intracortical excitability in human motor cortex
    Janine Reis
    Interdisciplinary Epilepsy Center, Department of Neurology, Philipps University, Marburg, Germany
    Epilepsia 43:1149-56. 2002
    ..In vitro studies suggest activity as sodium-channel blocker, as gamma-aminobutyric acid type A (GABAA)-receptor agonist and as non-N-methyl-D-aspartate (NMDA)-glutamate receptor antagonist...
  37. ncbi Focal reduction of intracortical inhibition in the motor cortex by selective proprioceptive stimulation
    Karin Rosenkranz
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square 8 11, London, WC1N 3BG, UK
    Exp Brain Res 149:9-16. 2003
    ..We suggest that MV induces a focused motorcortical activation which relies on a reduced activity of intracortical inhibitory interneuronal circuits targeting selectively the motorcortical representation of the vibrated muscle...
  38. ncbi Consolidation of human motor cortical neuroplasticity by D-cycloserine
    Michael A Nitsche
    Department Clinical Neurophysiology, Georg August University, Goettingen, Germany
    Neuropsychopharmacology 29:1573-8. 2004
    ....
  39. ncbi Timing-dependent modulation of associative plasticity by general network excitability in the human motor cortex
    Michael A Nitsche
    Georg August University, Department for Clinical Neurophysiology, 37075 Goettingen, Germany
    J Neurosci 27:3807-12. 2007
    ..These findings might be of importance for the development of plasticity-inducing stimulation protocols supporting information processing in humans...
  40. ncbi Safety criteria for transcranial direct current stimulation (tDCS) in humans
    Michael A Nitsche
    Clin Neurophysiol 114:2220-2; author reply 2222-3. 2003
  41. ncbi Human cortical motor representation of the larynx as assessed by transcranial magnetic stimulation (TMS)
    Ralph M W Rödel
    University of Gottingen, Gottingen, Lower Saxonia, Germany
    Laryngoscope 114:918-22. 2004
    ....