H Reichmann

Summary

Affiliation: Technical University
Country: Germany

Publications

  1. ncbi request reprint Efficacy of combining levodopa with entacapone on quality of life and activities of daily living in patients experiencing wearing-off type fluctuations
    H Reichmann
    Department of Neurology, Medical Faculty of the Technical University, Dresden, Germany
    Acta Neurol Scand 111:21-8. 2005
  2. ncbi request reprint [Diagnosis and therapy of idiopathic Parkinson's disease]
    Heinz Reichmann
    Klinik und Poliklinik fur Neurologie, Technische Universitat Dresden
    MMW Fortschr Med . 2006
  3. ncbi request reprint Changing dopamine agonist treatment in Parkinson's disease: experiences with switching to pramipexole
    H Reichmann
    Department of Neurology, Technical University of Dresden, Dresden, Germany
    J Neural Transm Suppl . 2006
  4. doi request reprint Modern treatment in Parkinson's disease, a personal approach
    Heinz Reichmann
    Department of Neurology, Technische Universitaet Dresden, Fetscherstrasse 74, 01307, Dresden, Germany
    J Neural Transm (Vienna) 123:73-80. 2016
  5. doi request reprint Optimizing levodopa therapy to treat wearing-off symptoms in Parkinson's disease: focus on levodopa/carbidopa/entacapone
    Heinz Reichmann
    Department of Neurology, University of Dresden, Dresden, Germany
    Expert Rev Neurother 12:119-31. 2012
  6. ncbi request reprint Mitochondrial dysfunction--a pathogenetic factor in Parkinson's disease
    H Reichmann
    Department of Neurology, Technical University of Dresden, Germany
    J Neurol 247:II63-8. 2000
  7. ncbi request reprint [1st long-term double-blind study of effectiveness and dyskinesia prevention of ropinirol]
    H Reichmann
    Klinik und Poliklinik fur Neurologie, Carl Gustav Carus Fakultät, Technische Universitat Dresden, Fetscherstrasse 74, 01307 Dresden
    Nervenarzt 71:1012-4. 2000
  8. ncbi request reprint [New approaches to transplantation of dopamine-producing cells and stem cells]
    H Reichmann
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden
    Nervenarzt 74:S22-6. 2003
  9. ncbi request reprint [Practical experience on improving activities of daily living competence in Parkinson's patients treated with ropinirole. Results of a applied study]
    H Reichmann
    Neurologische Universitätsklinik Dresden
    Nervenarzt 76:1239-40, 1242-5. 2005
  10. ncbi request reprint Budipine in Parkinson's tremor
    Heinz Reichmann
    Department of Neurology, University of Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
    J Neurol Sci 248:53-5. 2006

Collaborators

Detail Information

Publications120 found, 100 shown here

  1. ncbi request reprint Efficacy of combining levodopa with entacapone on quality of life and activities of daily living in patients experiencing wearing-off type fluctuations
    H Reichmann
    Department of Neurology, Medical Faculty of the Technical University, Dresden, Germany
    Acta Neurol Scand 111:21-8. 2005
    ....
  2. ncbi request reprint [Diagnosis and therapy of idiopathic Parkinson's disease]
    Heinz Reichmann
    Klinik und Poliklinik fur Neurologie, Technische Universitat Dresden
    MMW Fortschr Med . 2006
    ..In advanced stages with motor fluctuations, apomorphine or Duodopa pumps or deep brain stimulation are employed...
  3. ncbi request reprint Changing dopamine agonist treatment in Parkinson's disease: experiences with switching to pramipexole
    H Reichmann
    Department of Neurology, Technical University of Dresden, Dresden, Germany
    J Neural Transm Suppl . 2006
    ..The switch to pramipexole mostly yielded further improvements irrespective of the mode of switching...
  4. doi request reprint Modern treatment in Parkinson's disease, a personal approach
    Heinz Reichmann
    Department of Neurology, Technische Universitaet Dresden, Fetscherstrasse 74, 01307, Dresden, Germany
    J Neural Transm (Vienna) 123:73-80. 2016
    ..The use of all oral and invasive treatment has to be individualized to gain a good motor and non-motor control and especially a good quality of life. ..
  5. doi request reprint Optimizing levodopa therapy to treat wearing-off symptoms in Parkinson's disease: focus on levodopa/carbidopa/entacapone
    Heinz Reichmann
    Department of Neurology, University of Dresden, Dresden, Germany
    Expert Rev Neurother 12:119-31. 2012
    ..Here, we review the limitations of conventional levodopa and the clinical data for levodopa/carbidopa/entacapone in treating patients with wearing-off...
  6. ncbi request reprint Mitochondrial dysfunction--a pathogenetic factor in Parkinson's disease
    H Reichmann
    Department of Neurology, Technical University of Dresden, Germany
    J Neurol 247:II63-8. 2000
    ..A decrease in complex I activity in postmitotic cells may be one of the crucial factors for cell death...
  7. ncbi request reprint [1st long-term double-blind study of effectiveness and dyskinesia prevention of ropinirol]
    H Reichmann
    Klinik und Poliklinik fur Neurologie, Carl Gustav Carus Fakultät, Technische Universitat Dresden, Fetscherstrasse 74, 01307 Dresden
    Nervenarzt 71:1012-4. 2000
    ..The long-term experience gained in this 5-year study support our recommendations to use dopamine agonists early and as the preferred drug of choice in the treatment of Parkinson's disease...
  8. ncbi request reprint [New approaches to transplantation of dopamine-producing cells and stem cells]
    H Reichmann
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden
    Nervenarzt 74:S22-6. 2003
  9. ncbi request reprint [Practical experience on improving activities of daily living competence in Parkinson's patients treated with ropinirole. Results of a applied study]
    H Reichmann
    Neurologische Universitätsklinik Dresden
    Nervenarzt 76:1239-40, 1242-5. 2005
    ..Side effects were reported in only 7.6%. The results of this postmarketing study corroborate the good clinical efficacy of ropinirole together with high safety under routine clinical conditions...
  10. ncbi request reprint Budipine in Parkinson's tremor
    Heinz Reichmann
    Department of Neurology, University of Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
    J Neurol Sci 248:53-5. 2006
    ..Nonetheless, budipine in our hands is a most useful and safe drug to treat tremor and other main symptoms of Parkinson's disease...
  11. doi request reprint Non-motor features of Parkinson's disease: depression and dementia
    Heinz Reichmann
    Department of Neurology, Dresden University of Technology, Germany
    Parkinsonism Relat Disord 15:S87-92. 2009
    ..These symptoms not only occur during the course of the disease but may even precede the onset of motor symptoms. Typical examples of non-motor features of PD are depression, constipation, REM sleep behaviour disorder, and hyposmia...
  12. doi request reprint [Future standards in diagnosing Parkinson syndrome]
    H Reichmann
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Dresden
    Fortschr Neurol Psychiatr 78:S5-7. 2010
    ..In my own view, each PD patient should receive once in his career a cranial CT or MRI...
  13. doi request reprint Clinical criteria for the diagnosis of Parkinson's disease
    Heinz Reichmann
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Carl Gustav Carus, Dresden, Germany
    Neurodegener Dis 7:284-90. 2010
    ..Using all of these methods, we may soon be able to make a premotor diagnosis of PD, which will raise the question whether early treatment is possible and ethically and clinically advisable...
  14. ncbi request reprint Pergolide protects dopaminergic neurons in primary culture under stress conditions
    G Gille
    Department of Neurology, Technical University of Dresden, Federal Republic of Germany
    J Neural Transm (Vienna) 109:633-43. 2002
    ..Furthermore, between 0.001-0.1 microM it also reduced lactate production thus promoting aerobic metabolism. The present findings suggest that pergolide protects dopaminergic neurons under conditions of elevated oxidative stress...
  15. ncbi request reprint Analysis of the polymorphic prion protein gene codon 129 in idiopathic Parkinson's disease
    G Gossrau
    Department of Neurology, University of Technology, Dresden, Germany
    J Neural Transm (Vienna) 113:331-7. 2006
    ..In conclusion, genotype distribution at codon 129 is obviously not essential in determining IPD. But our results may provide first evidence of an association between certain PRNP129 polymorphisms and the clinical presentation of IPD...
  16. doi request reprint Baroreflex sensitivity and power spectral analysis in different extrapyramidal syndromes
    C Friedrich
    Autonomic and Neuroendocrinological Laboratory, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology, Fetscherstrasse 74, 01307, Dresden, Germany
    J Neural Transm (Vienna) 115:1527-36. 2008
    ..This may have fundamental impact on the cardiovascular prognosis of patients with extrapyramidal disease...
  17. doi request reprint [Impulsive-compulsive behaviours in a German Parkinson's disease outpatient sample]
    K Rohde
    Division für Neurodegenerative Erkrankungen, Klinik fur Neurologie, Technische Universitat Dresden, Germany
    Fortschr Neurol Psychiatr 81:503-10. 2013
    ..These include impulse control disorders (ICDs), repetitive behaviour (RB) and the dopamine-dysregulation syndrome (DDS)...
  18. ncbi request reprint Synergistic effect of alpha-dihydroergocryptine and L-dopa or dopamine on dopaminergic neurons in primary culture
    G Gille
    Department of Neurology, Technical University, Dresden, Germany
    J Neural Transm (Vienna) 113:1107-18. 2006
    ..DA receptor stimulation plays a decisive role. The synergistic effect suggests that a combinatory therapy can be beneficial to slow the degeneration of dopaminergic neurons...
  19. doi request reprint Circadian cortisol, depressive symptoms and neurological impairment in early multiple sclerosis
    S Kern
    Neurology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany
    Psychoneuroendocrinology 36:1505-12. 2011
    ..At the same time, depressive symptoms are often associated with an elevated circadian cortisol secretion. So far, little is known about the interplay between depressive symptoms and circadian HPA axis abnormalities in MS...
  20. doi request reprint Depression and care-dependency in Parkinson's disease: results from a nationwide study of 1449 outpatients
    O Riedel
    Technische Universitaet Dresden, Institute of Clinical Psychology and Psychotherapy, Chemnitzer Strasse 46, 01187 Dresden, Germany
    Parkinsonism Relat Disord 18:598-601. 2012
    ..Older age, longer duration and increased severity of PD contribute to care-dependency in patients with untreated depression. Treatment of depression is associated with lower rates of care-dependency...
  21. ncbi request reprint High-dose therapy with ropinirole in patients with Parkinson's disease
    M Müngersdorf
    Department of Neurology, Technical University of Dresden, Federal Republic of Germany
    J Neural Transm (Vienna) 108:1309-17. 2001
    ..007). Side effects were mild. High-dose ropinirole (20-36 mg/day) was well tolerated and conferred significant clinical benefit on patients with motor fluctuations...
  22. doi request reprint Occurrence risk and structure of depression in Parkinson disease with and without dementia: results from the GEPAD Study
    Oliver Riedel
    Technische Universitaet Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
    J Geriatr Psychiatry Neurol 23:27-34. 2010
    ....
  23. ncbi request reprint [Pramipexole in Parkinson disease. Results of a treatment observation]
    H Reichmann
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Fetscherstrasse 74, 01307 Dresden
    Nervenarzt 73:745-50. 2002
    ..35-2.66 mg used in controlled trials. This signifies that the option to adjust dosage according to effectiveness and tolerability under routine conditions yields a considerably lower incidence of adverse effects...
  24. doi request reprint Regular lipoprotein apheresis maintains residual cardiovascular and microvascular function in patients with advanced atherosclerotic disease
    M Reimann
    Autonomic and Neuroendocrinological Laboratory, Dept of Neurology, University Hospital Carl Gustav Carus, Dresden Fetscherstr 74, 01307 Dresden, Germany
    Atheroscler Suppl 14:135-41. 2013
    ..To determine whether previously demonstrated beneficial short-term effects on cardiovascular function in regular users of lipoprotein apheresis would be sustainable over time...
  25. pmc Treatment of Parkinson's disease in the advanced stage
    C Ossig
    Department of Neurology, Dresden University of Technology, Dresden, Germany
    J Neural Transm (Vienna) 120:523-9. 2013
    ..The physician's responsibility is to choose the right therapeutic procedure for each timepoint of the patient's disease. In this review, we provide an up to date overview of the available strategies...
  26. ncbi request reprint [Entacapone for treatment of motor fluctuations in idiopathic Parkinson syndrome]
    U Sommer
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Carl Gustav Carus, Dresden
    Nervenarzt 73:761-4. 2002
    ..This prospective and open study shows that an add-on therapy with entacapone can significantly lower wearing-off and end-of-dose akinesia. This treatment is well tolerated and easy to perform...
  27. doi request reprint Education research: cognitive performance is preserved in sleep-deprived neurology residents
    M Reimann
    ANF Laboratory, Department of Neurology, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    Neurology 73:e99-e103. 2009
    ..To test the hypotheses that sleep deprivation in neurology residents is associated with performance deficits and that vigilance and cognitive performance is more compromised after overnight on-call duty compared to night shift...
  28. doi request reprint The cold hand sign in multiple system atrophy: skin perfusion revisited
    K Pietzarka
    Autonomic and Neuroendocrinological Laboratory, Department of Neurology, University of Technology Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
    J Neural Transm (Vienna) 117:475-9. 2010
    ..By measuring skin temperature and blood flow, the presence of CHS can be diagnosed in MSA patients. Further studies are necessary to understand regulation of skin perfusion in patients with extrapyramidal disease...
  29. doi request reprint [Treatment of autonomic dysfunction in patients with extrapyramidal disorders]
    C Friedrich
    Autonomes und neuroendokrinologisches Funktionslabor, Neurologische Klinik und Poliklinik, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden
    Fortschr Neurol Psychiatr 78:445-55. 2010
    ..This review presents a limited overview on the treatment of cardiovascular, gastrointestinal, urogenital and sudomotor autonomic dysfunctions in various extrapyramidal syndromes...
  30. doi request reprint Rapidly progressive course of very late onset multiple sclerosis presenting with Parkinsonism: case report
    T Schultheiss
    Department of Neurology, University Hospital Gustav Carus, Technische Universitat Dresden, Germany
    Mult Scler 17:245-9. 2011
    ..Future trials to elucidate potential benefit of immunosuppressive (and neuroprotective) therapies in these age groups are mandatory...
  31. ncbi request reprint Olfactory function in Parkinsonian syndromes
    A Muller
    Department of Neurology, University of Dresden Medical School, 01307 Dresden, Germany
    J Clin Neurosci 9:521-4. 2002
    ..These data suggest that olfactory probes improve the diagnostic armamentarium in IPD...
  32. ncbi request reprint Switching and combining dopamine agonists
    H Reichmann
    Department of Neurology, Technical University of Dresden, Dresden, Germany
    J Neural Transm (Vienna) 110:1393-400. 2003
    ..This paper describes some ideas on the most practical way to perform switching. In addition, it describes the possibilities of combining various dopamine agonists and discusses pros and cons for doing so...
  33. ncbi request reprint Olfactory function in patients with idiopathic Parkinson's disease: effects of deep brain stimulation in the subthalamic nucleus
    T Hummel
    Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden, Medical School, Dresden, Germany
    J Neural Transm (Vienna) 112:669-76. 2005
    ..This may indicate that deep brain stimulation has a positive effect on the cognitive processing of olfactory information in PD patients...
  34. doi request reprint Valsalva manoeuvre in patients with different Parkinsonian disorders
    C Schmidt
    Autonomic and Neuroendocrinological Laboratory, Department of Neurology, University Clinic Carl Gustav Carus, Dresden University of Technology, Fetscherstrasse 74, Dresden 01307, Germany
    J Neural Transm (Vienna) 116:875-80. 2009
    ..Metronomic breathing and tilt-table test seem more capable as parasympathetic resp. and sympathetic function tests to identify cardiovascular abnormalities in PS patients...
  35. doi request reprint Immunohistochemical, volumetric, and functional neuroimaging studies in patients with idiopathic Parkinson's disease
    T Hummel
    Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Dresden, Germany
    J Neurol Sci 289:119-22. 2010
    ..Thus, it seems that cerebral changes, and not changes at the level of the olfactory epithelium, are the basis of the olfactory loss observed in PD patients...
  36. doi request reprint Efficacy and tolerability of rasagiline in daily clinical use--a post-marketing observational study in patients with Parkinson's disease
    H Reichmann
    Department of Neurology, University of Dresden, Dresden, Germany
    Eur J Neurol 17:1164-71. 2010
    ..The post-marketing observational study presented here investigated the efficacy and tolerability of rasagiline treatment (monotherapy or combination therapy) in daily clinical practice...
  37. ncbi request reprint Noninvasive assessment of the circle of Willis in cerebral ischemia: the potential of CT angiography and contrast-enhanced transcranial color-coded duplexsonography
    G Gahn
    Department of Neurology, University of Dresden, Germany
    Cerebrovasc Dis 9:290-4. 1999
    ..CT angiography and contrast-enhanced TCCD are complementary noninvasive diagnostic tools. Disagreements between the diagnostic findings of these methods still need further evaluation by digital subtraction angiography...
  38. ncbi request reprint [Early detection of Parkinson syndrome]
    U Sommer
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Carl Gustav Carus, Dresden
    Orthopade 32:82-4. 2003
  39. ncbi request reprint HLA typing and Parkinson's disease
    J B Lampe
    Department of Neurology, University of Technology, Dresden, Germany
    Eur Neurol 50:64-8. 2003
    ..002) in IPD which may indicate an association between IPD and the immune system. Alternatively, HLA alleles might be in linkage disequilibrium with genes located next to the HLA locus...
  40. ncbi request reprint Olfactory bulb volumes in patients with idiopathic Parkinson's disease a pilot study
    A Mueller
    Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Dresden, Germany
    J Neural Transm 112:1363-70. 2005
    ....
  41. ncbi request reprint [Medication treatment for Parkinson's disease]
    H Reichmann
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden
    Nervenarzt 76:1547-57; quiz 1558. 2005
    ..It is important to sustain patient confidence. Although parkinsonism is an insidious disease of unknown cause resulting in destruction of important dopaminergic neurons, no other neurodegenerative disease can be treated as successfully...
  42. ncbi request reprint Kinetic tremor in Parkinson's disease--an underrated symptom
    P H Kraus
    Department of Neurology, St Josef Hospital, University of Bochum, Bochum, Germany
    J Neural Transm (Vienna) 113:845-53. 2006
    ..The results indicate that a combination of rest, postural and kinetic tremors constitute the most frequent tremor constellation in PD...
  43. ncbi request reprint Non-motor dysfunction in Parkinson's disease
    Tjalf Ziemssen
    Neurological University Clinic, Technische Universitat Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
    Parkinsonism Relat Disord 13:323-32. 2007
    ..The early recognition of these symptoms may well perhaps lead to an earlier diagnosis of PD, but in any case should lead to more prompt and effective treatment of the relatively unrecognized non-motor problems associated with PD...
  44. doi request reprint Cognitive impairment in 873 patients with idiopathic Parkinson's disease. Results from the German Study on Epidemiology of Parkinson's Disease with Dementia (GEPAD)
    Oliver Riedel
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Chemnitzer Strasse 46, Dresden, Germany
    J Neurol 255:255-64. 2008
    ..Prevalence estimates of these complications are quite variable and are lacking for the outpatient care sector...
  45. pmc Alzheimer's Disease: Differences of Transdermal versus Oral Treatment on Caregiving Time
    O Riedel
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
    Dement Geriatr Cogn Dis Extra 2:468-80. 2012
    ..We explored differences between patients with oral and transdermal application of acetylcholine esterase inhibitors regarding caregiver's time burden and psychopathology...
  46. ncbi request reprint [Proximal weakness and exercise-induced pain as initial symptom of oculopharyngeal muscular dystrophy]
    J B Lampe
    , , Fetscherstrasse 74, 01307 Dresden
    Nervenarzt 72:652-5. 2001
    ..Exercise-induced proximal muscle pain and weakness are rarely initial symptoms of OPMD. We discuss therapeutic options and present an overview of the relevant literature...
  47. ncbi request reprint Apolipoprotein E and alpha-1-antichymotrypsin polymorphisms in sporadic inclusion body myositis
    G Gossrau
    Department of Neurology, Medical Clinic II, Technical University Dresden, Dresden, Germany
    Eur Neurol 51:215-20. 2004
    ..A combination of different alpha1-ACT and ApoE genotypes appears not to enhance the risk of developing s-IBM. Therefore, allelic variations of alpha1-ACT and ApoE are unlikely to be genetic key factors in the aetiology of s-IBM...
  48. doi request reprint Neurological disability, psychological distress, and health-related quality of life in MS patients within the first three years after diagnosis
    S Kern
    Department of Neurology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Germany
    Mult Scler 15:752-8. 2009
    ..Psychological distress and psychiatric co-morbidity are common in multiple sclerosis (MS) and is often associated with neurological disability as well as reduced quality of life...
  49. ncbi request reprint Transcatheter closure of patent foramen ovale (PFO) in patients with paradoxical embolism. Periprocedural safety and mid-term follow-up results of three different device occluder systems
    M Braun
    Internal Medicine II, Department of Cardiology, Technical University of Dresden, Fetscherstr 76, 01307 Dresden, Germany
    Eur Heart J 25:424-30. 2004
    ..The aim of the present study was to evaluate three different occluder systems in respect to (a) the safety and practicability and (b) the mid-term risk of recurrent thromboembolic events...
  50. ncbi request reprint [Muscular atrophy as a symptom]
    J Schmiedel
    Klinik und Poliklinik fur Neurologie, Carl Gustav Carus Universität Dresden
    Internist (Berl) 45:1163-73; quiz 1174-5. 2004
    ..To achieve this it is necessary to be aware of the large number of diseases that can induce this in order to ensure timely referral to a specialist...
  51. ncbi request reprint [Thunderclap headache caused by cerebellar infarction]
    G Gossrau
    Universitätsschmerzzentrum, Universitätsklinikum der TU Dresden, Fetscherstr 74, 01309, Dresden, Deutschland
    Schmerz 22:82-6. 2008
    ....
  52. doi request reprint [Parainfectious polyneuropathy and miller-fisher-syndrome in combination with anemia in Mycoplasma pneumoniae infection]
    K F Loewenbrück
    Klinik und Poliklinik fur Neurologie, Universitätsklinik Carl Gustav Carus Dresden
    Fortschr Neurol Psychiatr 76:361-5. 2008
    ..With this report we would like to stress the importance to include M.p. in the diagnostic procedures in the case of inflammatory neurological syndromes, especially when combined with alterations of the blood count...
  53. ncbi request reprint Neuroprotection in idiopathic Parkinson's disease
    Heinz Reichmann
    Department of Neurology, University of Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
    J Neurol 249:III/21-3. 2002
    ..We certainly have to continue our search for even better tools to evaluate neuroprotection...
  54. ncbi request reprint Mitochondrial cytopathies
    Janet Schmiedel
    Department of Neurology, Carl Gustav Carus University Dresden, Fetscherstr 74, 01307 Dresden, Germany
    J Neurol 250:267-77. 2003
    ..To date, the treatment of these diseases remains supportive and should focus on typical complications such as cardiac dysrhythmia and endocrinopathy...
  55. ncbi request reprint Metabolic patterns in meningiomas
    Birgit Herting
    Department of Neurology, University Dresden, Germany
    J Neurooncol 65:119-23. 2003
    ..5-6 in the tumours. Further analysis of the histological subtypes showed that phosphofructokinase and lactate dehydrogenase were significantly increased in the anaplastic meningiomas compared to the benign subtypes...
  56. ncbi request reprint Switching and combining of dopamine agonists
    Susann Junghanns
    Department of Neurology, Carl Gustav Carus University Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
    J Neurol 251:VI/19-23. 2004
    ..This article explores some more motives for switching and combining of dopamine agonists in consideration of practical aspects and very recently published data...
  57. ncbi request reprint Prefrontal cortex dysfunction and depression in atypical parkinsonian syndromes
    Birgit Herting
    Department of Neurology, Technische Universitat Dresden, Germany
    Mov Disord 22:490-7. 2007
    ..The findings of this pilot study support the hypothesis that depressive symptoms in MSA and PSP are associated with prefrontal dysfunction...
  58. ncbi request reprint Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease
    Alexander Storch
    Department of Neurology, Technical University of Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
    Arch Neurol 64:938-44. 2007
    ..Coenzyme Q(10) (CoQ(10)) is an electron acceptor bridging mitochondrial complexes I and II/III and a potent antioxidant that consistently partially recovers the function of dopaminergic neurons...
  59. doi request reprint Potassium channel blocker 4-aminopyridine is effective in interictal cerebellar symptoms in episodic ataxia type 2--a video case report
    Matthias Lohle
    Department of Neurology, Technical University of Dresden, Dresden, Germany
    Mov Disord 23:1314-6. 2008
    ..i.d., there was pronounced improvement in gait and stance ataxia. Within 24 hours SARA score lowered from 8.5 to 4.5 points. We conclude that 4-AP may be beneficial for interictal cerebellar ataxia in late onset EA2...
  60. doi request reprint Chocolate consumption is increased in Parkinson's disease. Results from a self-questionnaire study
    Martin Wolz
    Dept of Neurology, Dresden University of Technology, Fetscherstrasse 74, 01307, Dresden, Germany
    J Neurol 256:488-92. 2009
    ..Although reasons for increased chocolate consumption in PD remain elusive, it may hypothetically be a consequence of the high content of various biogenic amines and/or caffeine analogues with potential antiparkinsonian effects...
  61. doi request reprint Beyond tremor and rigidity: non-motor features of Parkinson's disease
    Matthias Lohle
    Department of Neurology, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    J Neural Transm (Vienna) 116:1483-92. 2009
    ..This article aims to provide an overview of frequently observed non-motor features in PD and discusses prospects and limitations of currently available options for symptomatic treatment of these disturbances...
  62. doi request reprint Clinical neuroprotection in Parkinson's disease - still waiting for the breakthrough
    Matthias Lohle
    Department of Neurology, Dresden University of Technology, Germany
    J Neurol Sci 289:104-14. 2010
    ..Just as the pathogenesis of the disease is manifold, it may be this multilateral approach that eventually leads us to a breakthrough in finding neuroprotective agents for PD, if they exist...
  63. doi request reprint [Multiple sclerosis management system 3D. Moving from documentation towards management of patients]
    T Schultheiss
    Klinik fur Neurologie, Universitätsklinik Dresden, Fetscherstr 74, 01307, Dresden, Deutchland
    Nervenarzt 83:450-7. 2012
    ..To switch from pure MS documentation to MS management by implementing a new multiple sclerosis management and documentation tool may be of importance...
  64. ncbi request reprint Cabergoline protects dopaminergic neurons against rotenone-induced cell death in primary mesencephalic cell culture
    J Meinel
    Ass Prof Gabriele Gille, Department of Neurology, Technical University, Fetscherstr 74, 01307 Dresden, Germany, E mail
    Folia Neuropathol 53:29-40. 2015
    ..This effect was independent of dopamine receptor stimulation and was at least partially mediated by reducing ROS production and increasing the ATP/protein ratio. ..
  65. ncbi request reprint Subcutaneous microdialysis in mitochondrial cytopathy
    M S Damian
    Department of Neurology, Technical University of Dresden, Fetscherstrasse 74, Dresden 01307, Germany
    Muscle Nerve 24:648-53. 2001
    ..It has particular potential for use in the identification of metabolic risk factors and may help to assess the impact of therapeutic regimens...
  66. ncbi request reprint Protection of dopaminergic neurons in primary culture by lisuride
    G Gille
    Department of Neurology, Technical University of Dresden, Federal Republic of Germany
    J Neural Transm (Vienna) 109:157-69. 2002
    ..Lisuride also reduces anaerobic metabolism during incubation with L-DOPA. The present findings suggest that lisuride may have trophic/survival-promoting properties and potentially reduces oxidative stress...
  67. doi request reprint Prevalence of smell loss in Parkinson's disease--a multicenter study
    A Haehner
    Department of Otorhinolaryngology, University of Dresden Medical School, Dresden, Germany
    Parkinsonism Relat Disord 15:490-4. 2009
    ..This figure falls to 74.5%, however, when adjusted to age-related norms. Thus, olfactory dysfunction should be considered as a reliable marker of the disease...
  68. ncbi request reprint Detection of presymptomatic Parkinson's disease: combining smell tests, transcranial sonography, and SPECT
    Ulrike Sommer
    Department of Neurology, University of Dresden Medical School, Dresden, Germany
    Mov Disord 19:1196-202. 2004
    ..Longitudinal follow-up studies are necessary to estimate the ratio of patients with dopaminergic cell loss in the basal ganglia who will develop PD in the future...
  69. ncbi request reprint Extrapyramidal symptoms in Wilson's disease are associated with olfactory dysfunction
    Antje Mueller
    Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Dresden, Germany
    Mov Disord 21:1311-6. 2006
    ....
  70. ncbi request reprint Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic culture
    Juliane Hamann
    Department of Neurology, Technical University of Dresden, Dresden, Germany
    J Neurochem 98:1185-99. 2006
    ..These data underline the preferential susceptibility of dopaminergic neurones to 2,9-Me(2)NH(+) as a potent, oxidative stress generating neurotoxin...
  71. ncbi request reprint Valvular heart disease in Parkinson's disease patients treated with dopamine agonists: a reader-blinded monocenter echocardiography study
    Susann Junghanns
    Department of Neurology, Technical University of Dresden, Dresden, Germany
    Mov Disord 22:234-8. 2007
    ..Our data suggest that ergot DAs are associated with higher prevalence of VHD compared to non-ergot DAs and controls. Standard echocardiography seems sufficient to detect VHD in PD patients treated with DAs...
  72. doi request reprint Comprehensive autonomic assessment does not differentiate between Parkinson's disease, multiple system atrophy and progressive supranuclear palsy
    Manja Reimann
    Department of Neurology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Fetscherstr 74, 01307, Dresden, Germany
    J Neural Transm (Vienna) 117:69-76. 2010
    ..Thus, clinical combination of motor and non-motor symptoms does not exclusively point at MSA. Pupillography, ABPM and the questionnaire may assist in delineating the three syndromes when applied in combination...
  73. pmc Protocol for German trial of Acyclovir and corticosteroids in Herpes-simplex-virus-encephalitis (GACHE): a multicenter, multinational, randomized, double-blind, placebo-controlled German, Austrian and Dutch trial [ISRCTN45122933]
    Francisco Martinez-Torres
    Department of Neurology, University of Heidelberg, Germany
    BMC Neurol 8:40. 2008
    ..But currently there is no available evidence to support the routine use of adjuvant corticosteroid treatment in HSVE. A randomized multicenter trial is the only useful instrument to address this question...
  74. ncbi request reprint Modafinil for excessive daytime sleepiness in myotonic dystrophy
    M S Damian
    Department of Neurology, Carl Gustav Carus University Hospital, University of Technology, Dresden, Germany
    Neurology 56:794-6. 2001
    ..00013), and average Epworth Sleepiness Scale score decreased from 13.25 to 7.75 (p = 0.01028). Modafinil shows evidence of effectiveness for excessive daytime somnolence in myotonic dystrophy and should be investigated further...
  75. ncbi request reprint Novel mitochondrial DNA mutations in Parkinson's disease
    G Richter
    Department of Neurology, Technical University of Dresden, Federal Republic of Germany
    J Neural Transm (Vienna) 109:721-9. 2002
    ....
  76. ncbi request reprint [Miller Fisher syndrome: case report and review with discussion of differential diagnosis and nosology]
    U Becker
    Klinik und Poliklinik fur Neurologie, Fetscherstrasse 74, 01307, Dresden
    Nervenarzt 77:716-21. 2006
    ....
  77. doi request reprint [Elektrophysiological methods as diagnostic tools in pain therapy]
    G Gossrau
    Universitätsschmerzzentrum, Universitätsklinikum der TU Dresden, Fetscherstrasse 74, 01309, Dresden, Deutschland
    Schmerz 22:471-9; quiz 80-1. 2008
    ..Investigation of the sympathetic sudomotoric system can provide evidence for lesions within sympathetic nerves...
  78. doi request reprint CD49d blockade by natalizumab in patients with multiple sclerosis affects steady-state hematopoiesis and mobilizes progenitors with a distinct phenotype and function
    D Jing
    Department of Hematology and Oncology, University Hospital Dresden, Dresden, Germany
    Bone Marrow Transplant 45:1489-96. 2010
    ..Our data indicate that G-CSF and CD49d blockade mobilize different HSC subsets and suggest that both strategies may be differentially applied in specific cell therapy approaches...
  79. doi request reprint Autonomic dysfunction in patients with progressive supranuclear palsy
    Claudia Schmidt
    Autonomic and Neuroendocrinological Laboratory ANF, University Clinic Carl Gustav Carus, Dresden University of Technology, Germany
    Mov Disord 23:2083-9. 2008
    ..Our findings have a profound implication on the diagnosis and treatment of PSP patients...
  80. ncbi request reprint Treatment strategies for nonmotor manifestations of Parkinson's disease
    Heinz Reichmann
    Department of Neurology, University of Technology Dresden, Dresden, Germany
    Expert Opin Pharmacother 10:773-84. 2009
    ..Unfortunately, hardly any double-blind, randomized, controlled studies are available, with the consequence that most recommendations are not based on the highest level of evidence...
  81. doi request reprint Loss of nocturnal blood pressure fall in various extrapyramidal syndromes
    Claudia Schmidt
    Autonomic and Neuroendocrinological Laboratory, University Clinic Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    Mov Disord 24:2136-42. 2009
    ..Pathological loss of nocturnal BP fall may account for increased cardiovascular mortality in extrapyramidal syndromes...
  82. doi request reprint Olfactory dysfunction as a diagnostic marker for Parkinson's disease
    Antje Haehner
    Departments of Otorhinolaryngology and Neurology, University of Dresden Medical School, Fetscherstrasse 74, 01307 Dresden, Germany
    Expert Rev Neurother 9:1773-9. 2009
    ..This review summarizes the available information about olfactory function in PD, indicating the advantageous use of olfactory probes in early and differential diagnosis...
  83. doi request reprint Utility of the WHO-Five Well-being Index as a screening tool for depression in Parkinson's disease
    Christine B Schneider
    Department of Neurology, Dresden University of Technology, Dresden, Germany
    Mov Disord 25:777-83. 2010
    ..234). The optimal cut-off value for detection of depression was 12 of 13 points. WHO-5 is a useful, brief, and easy instrument for identifying PD subjects with depression in daily practice...
  84. doi request reprint The exceptional properties of 9-methyl-beta-carboline: stimulation, protection and regeneration of dopaminergic neurons coupled with anti-inflammatory effects
    Witold Polanski
    Department of Neurology, Technical University of Dresden, Dresden, Germany
    J Neurochem 113:1659-75. 2010
    ..Further investigations are currently under way...
  85. pmc New insights into the pharmacokinetics and pharmacodynamics of natalizumab treatment for patients with multiple sclerosis, obtained from clinical and in vitro studies
    T Sehr
    Neuroimmunological Lab, Center of Clinical Neuroscience, Neurological Clinic, University Hospital Carl Gustav Carus, Dresden University of Technology, Fetscherstraße 74, D 01307, Dresden, Germany
    J Neuroinflammation 13:164. 2016
    ..We evaluated the effects of different NAT treatment regimens...
  86. doi request reprint [Organized Post-Stroke Care through Case Management on the Basis of a Standardized Treatment Pathway : Results of a Single-Centre Pilot Study]
    J Barlinn
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Carl Gustav Carus Dresden, Technische Universitat Dresden, Fetscherstraße 74, 01307, Dresden, Deutschland
    Nervenarzt 87:860-9. 2016
    ..Post-stroke care programs based on a standardized treatment pathway supported by case management may prevent secondary stroke and minimize risk factors...
  87. doi request reprint [Axon-reflex based nerve fiber function assessment in the detection of autonomic neuropathy]
    T Siepmann
    Klinik und Poliklinik fur Neurologie, Universitatsklinik Carl Gustav Carus, Technische Universitat Dresden, Dresden, Deutschland
    Nervenarzt 85:1309-14. 2014
    ..The effectiveness of new axon-reflex tests in the assessment of neuropathy is currently being investigated in clinical studies...
  88. ncbi request reprint Echo-enhanced transcranial color-coded duplexsonography to study collateral blood flow in patients with symptomatic obstructions of the internal carotid artery and limited acoustic bone windows
    G Gahn
    Department of Neurology, University of Technology Dresden, Fetscher Strasse 74, D 01307 Dresden, Germany
    Cerebrovasc Dis 11:107-12. 2001
    ....
  89. ncbi request reprint Cricopharyngeal achalasia is a common cause of dysphagia in patients with mtDNA deletions
    C Kornblum
    Department of Neurology, University of Bonn, Germany
    Neurology 56:1409-12. 2001
    ..Cricopharyngeal myotomy may be an effective treatment in selected cases with severe cricopharyngeal obstruction...
  90. ncbi request reprint [Gene expression profiling of classic mitochondrial disorders. Its value in finding therapeutic strategies]
    S Mende
    Klinik und Poliklinik fur Neurologie, Technische Universitat Dresden
    Nervenarzt 78:1155-9. 2007
    ..This review article focuses on the most recent gene expression profiling studies in the field of classic mitochondrial disorders...
  91. doi request reprint [Adherence to neurologic treatment. Lessons from multiple sclerosis]
    S Kern
    Klinik und Poliklinik fur Neurologie, Multiple Sklerose Zentrum, Carl Gustav Carus Universitätsklinik, Fetscherstrasse 74, 01307, Dresden
    Nervenarzt 79:877-8, 880-2, 884-6 passim. 2008
    ..Factors affecting treatment motivation in multiple sclerosis patients are summarized focusing on neurologic treatment issues, and specific intervention strategies for patients, doctors, and nurses are discussed...
  92. ncbi request reprint Pramipexole in routine clinical practice: a prospective observational trial in Parkinson's disease
    Heinz Reichmann
    Department of Neurology, Technical University of Dresden, Dresden, Germany
    CNS Drugs 17:965-73. 2003
    ..The study also aimed to demonstrate the practicability of the Snaith-Hamilton Pleasure Scale (SHAPS-D), the Tremor Impact Scale (TIS) and the Short Parkinson's Evaluation Scale (SPES) under conditions of routine clinical practice...
  93. ncbi request reprint Computed tomographically-controlled injection of botulinum toxin into the longus colli muscle in severe anterocollis
    Birgit Herting
    Department of Neurology, Carl Gustav Carus University, Dresden, Germany
    Mov Disord 19:588-90. 2004
    ..Repeated computed tomographically controlled injections of botulinum toxin into the right longus colli muscle allowed a precise location of the needle and injection of the toxin, leading to clear improvement of symptoms...
  94. ncbi request reprint Mitochondrial dysfunction in Parkinson's disease--revisited
    Heather Jane Mortiboys
    Department of Neurology, Technical University, Dresden, Germany
    Neurol Neurochir Pol 41:150-9. 2007
    ..In this review we will examine the data indicating the presence of a respiratory chain defect in patients with idiopathic PD and attempt to link it with the pathways that have been implicated by familial studies...
  95. ncbi request reprint Pupil diameter in darkness differentiates progressive supranuclear palsy (PSP) from other extrapyramidal syndromes
    Claudia Schmidt
    Autonomic and Neuroendocrinological Laboratory, University Clinic Carl Gustav Carus, Dresden University of Technology, Germany
    Mov Disord 22:2123-6. 2007
    ..4% and a sensitivity of 70.8%. Other pupil abnormalities could not be described in patients with extrapyramidal syndromes...
  96. ncbi request reprint 9-Methyl-beta-carboline up-regulates the appearance of differentiated dopaminergic neurones in primary mesencephalic culture
    Juliane Hamann
    Department of Neurology, Technical University of Dresden, Fetscherstr 74, 01307 Dresden, Germany
    Neurochem Int 52:688-700. 2008
    ....
  97. doi request reprint A longitudinal study of olfactory function in patients with idiopathic Parkinson's disease
    Birgit Herting
    Dept of Neurology, University of Dresden Medical School, Dresden, Germany
    J Neurol 255:367-70. 2008
    ..In this scenario, olfactory loss seen early in the disease may be based on an incomplete inhibition of olfactory input at the level of the olfactory bulb...
  98. doi request reprint Autonomic dysfunction in different subtypes of multiple system atrophy
    Claudia Schmidt
    Autonomic and Neuroendocrinological Laboratory, University of Dresden, Germany
    Mov Disord 23:1766-72. 2008
    ..Our results suggest that there are only minor differences in the pattern of autonomic dysfunction between the two clinical MSA phenotypes...
  99. doi request reprint Cardiovascular autonomic dysfunction in Parkinson's disease
    Tjalf Ziemssen
    ANF lab, Neurological University Clinic, Dresden, Germany
    J Neurol Sci 289:74-80. 2010
    ..Supine hypertension is often associated with orthostatic hypotension. The prognostic role of cardiovagal and baroreflex dysfunction is still not yet known...
  100. pmc Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice
    Francisco Pan-Montojo
    Institute of Anatomy, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    PLoS ONE 5:e8762. 2010
    ..It provides new insight into how environmental factors could trigger PD and suggests a transsynaptic mechanism by which PD might spread throughout the central nervous system...
  101. doi request reprint Transdermal delivery of dopamine receptor agonists
    Heinz Reichmann
    Department of Neurology, Dresden University of Technology, Dresden, Germany
    Parkinsonism Relat Disord 15:S93-6. 2009
    ..The disadvantages of patches are skin irritation and crystallization of the drug if not kept in the refrigerator...