- Analysis of mammalian brain architectureFahad Sultan
Department of Cognitive Neurology, University of Tubingen, Germany
Nature 415:133-4. 2002..Contrary to the conclusion drawn by Clark et al., this linear dependence of size implies that the two major cortices increase their computational capacity in parallel, suggesting a functional dependence of the one upon the other...
- From cerebellar texture to movement optimizationFahad Sultan
Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, Otfried Müller Str 21, 72076, Tubingen, Germany
Biol Cybern 108:677-88. 2014..The advantage of such a mechanism is that movements are optimized by reducing "jerkiness" which, in turn, lowers their energy requirements...
- Unravelling cerebellar pathways with high temporal precision targeting motor and extensive sensory and parietal networksFahad Sultan
Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Otfried Müller Str 27, 72076 Tubingen, Germany
Nat Commun 3:924. 2012..In conclusion, both the topography of the stimulation effects and its emphasis on temporal precision are in full accordance with the concept of cerebellar forward model information modulating cerebro-cortical processing...
- esfMRI of the upper STS: further evidence for the lack of electrically induced polysynaptic propagation of activity in the neocortexFahad Sultan
Department of Cognitive Neurology, HIH for Clinical Brain Research, Tuebingen 72076, Germany
Magn Reson Imaging 29:1374-81. 2011..We confirm our previous results from stimulating primary visual cortex that the propagation of electrically induced activity is limited in its transsynaptic propagation to the first synapse also for extrastriate areas...
- Detection of sequences in the cerebellar cortex: numerical estimate of the possible number of tidal-wave inducing sequences representedFahad Sultan
Department of Cognitive Neurology, University of Tubingen, Auf der Morgenstelle 15, 72076 Tubingen, Germany
J Physiol Paris 97:591-600. 2003..Based on anatomical data we will argue that the cerebellar mossy fiber-granule cell-Purkinje cell system can potentially detect and--through learning--select from an enormous number of spatio-temporal patterns...
- The cerebellum: Comparative and animal studiesFahad Sultan
Department of Cognitive Neurology, HIH for Clinical Brain Research, Tuebingen, Germany
Cerebellum 6:168-76. 2007..Finally, we review the connections of the mammalian cerebellum and show that several pieces of experimental evidence point to an important function of the cerebellum in sensory control of movement reflex adjustment, and motor learning...
- Morphological classification of the rat lateral cerebellar nuclear neurons by principal component analysisFahad Sultan
Department of Cognitive Neurology, Neurology Universitätsklinik, 72076 Tubingen, Germany
J Comp Neurol 455:139-55. 2003..The latter may be important for understanding the phylogenetic changes seen in the mammalian lateral cerebellar nucleus...
- Quantitative organization of neurotransmitters in the deep cerebellar nuclei of the Lurcher mutantFahad Sultan
Department of Cognitive Neurology, 72076 Tubingen, Germany
J Comp Neurol 452:311-23. 2002....
- The human dentate nucleus: a complex shape untangledF Sultan
Department of Cognitive Neurology, University Tübingen, Otfried Müllerstr 27, 72076 Tubingen, Germany
Neuroscience 167:965-8. 2010..We propose that this is to allow for a large number of independent corticonuclear modules that can modulate an equal large number of sequential motor acts...
- Distribution of mossy fibre rosettes in the cerebellum of cat and mice: evidence for a parasagittal organization at the single fibre levelF Sultan
Department of Cognitive Neurology, University Tübingen, Auf der Morgenstelle 15, 72076 Tubingen, Germany
Eur J Neurosci 13:2123-30. 2001..The anisotropic orientation of mossy fibres at the single fibre level supports the hypothesis of a timing mechanism in cerebellar function...
- Flat map areal topography in Macaca mulatta based on combined MRI and histologyFahad Sultan
Department of Cognitive Neurology, HIH for Clinical Brain Research, Tuebingen, Germany
Magn Reson Imaging 28:1159-64. 2010..Some differences arise due to different distinguishing criteria and here too flat maps can help to reveal them...
- Exploring a critical parameter of timing in the mouse cerebellar microcircuitry: the parallel fiber diameterF Sultan
Sektion fur Visuelle Sensomotorik, Neurologische Universitätsklinik Tübingen, Germany
Neurosci Lett 280:41-4. 2000....
- BOLD sensitivity to cortical activation induced by microstimulation: comparison to visual stimulationFahad Sultan
Department of Cognitive Neurology, HIH for Clinical Brain Research, University Tuebingen, 72076 Tuebingen, Germany
Magn Reson Imaging 25:754-9. 2007..However, electrical microstimulation yielded an even greater spread of the BOLD response. Our results confirm that the effects of electrical microstimulation extend beyond the brain region expected to be excited by direct current spread...
- The effects of electrical microstimulation on cortical signal propagationNikos K Logothetis
Max Planck Institute for Biological Cybernetics, Tubingen, Germany
Nat Neurosci 13:1283-91. 2010..Taken together, our findings suggest that electrical stimulation disrupts cortico-cortical signal propagation by silencing the output of any neocortical area whose afferents are electrically stimulated...
- Mapping cortical activity elicited with electrical microstimulation using FMRI in the macaqueAndreas S Tolias
Max Planck Institute for Biological Cybernetics, Tuebingen 72076, Germany
Neuron 48:901-11. 2005..Consistent with this functional transynaptic spread we also obtained activation in expected projection sites in extrastriate visual areas, demonstrating the utility of our technique in uncovering in vivo functional connectivity maps...
- An intact action-perception coupling depends on the integrity of the cerebellumAndrea Christensen
Section Computational Sensomotorics, Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, and Centre for Integrative Neuroscience, MRI Laboratory, Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, University Clinic Tübingen, 72076 Tubingen, Germany, and Department of Neurosurgery, Institute of Diagnostic and Interventional Radiology and Neuroradiology, and Department of Neurology, University of Duisburg Essen, 45147 Essen, Germany
J Neurosci 34:6707-16. 2014..Both the correct somatosensory as well as the multisensory state representations are vital for an intact APC. ..
- Lurcher mice exhibit potentiation of GABA(A)-receptor-mediated conductance in cerebellar nuclei neurons in close temporal relationship to Purkinje cell deathC Linnemann
Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, 72076 Tubingen, Germany
J Neurophysiol 91:1102-7. 2004..The changes in g(syn), suitable to increase the efficacy of GABAergic transmission, occur in close temporal relationship to PC death and, thus, may reflect a functional adaptation to the loss of the DCN's main GABAergic afferents...
- Systematic analysis of neuronal wiring of the rodent deep cerebellar nuclei reveals differences reflecting adaptations at the neuronal circuit and internuclear levelsSalah Hamodeh
Department of Cognitive Neurology, HIH for Clinical Brain Research, 72076, Tubingen, Germany
J Comp Neurol 522:2481-97. 2014..In summary, our results show previously unappreciated functional adaptations among these nuclei...
- The detection and generation of sequences as a key to cerebellar function: experiments and theoryV Braitenberg
Max Planck Institute for Biological Cybernetics, Tuebingen, Germany
Behav Brain Sci 20:229-45; discussion 245-77. 1997....
- Two types of neurons in the rat cerebellar nuclei as distinguished by membrane potentials and intracellular fillingsU Czubayko
, , 72076 Tubingen, Germany
J Neurophysiol 85:2017-29. 2001..In view of their size and scarcity, we propose that type II neurons may correspond to CN interneurons...
- Cerebellar structure and function: making sense of parallel fibersDetlef Heck
Institute of Biology III, Neurobiology and Biophysics, University of Freiburg, 79104 Freiburg, Germany
Hum Mov Sci 21:411-21. 2002....
- Why some bird brains are larger than othersFahad Sultan
Curr Biol 15:R649-50. 2005
- The cerebellum at birth in therian mammals, with special reference to rodentsMarcello R Sánchez-Villagra
Zoologisches Institut, Spezielle Zoologie, Universitat Tubingen, Tubingen, Germany
Brain Behav Evol 59:101-13. 2002..As is the case with placentals, the most advanced stage of cerebellar development coincides with the opening of the eyes...