Andreas Sprenger

Summary

Country: Germany

Publications

  1. doi request reprint Enhanced top-down control during pursuit eye tracking in schizophrenia
    Andreas Sprenger
    Department of Neurology, University Luebeck, Luebeck, Germany
    Eur Arch Psychiatry Clin Neurosci 263:223-31. 2013
  2. pmc Distributed representations of the "preparatory set" in the frontal oculomotor system: a TMS study
    M Nagel
    Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, Luebeck, Germany
    BMC Neurosci 9:89. 2008
  3. doi request reprint Long-term eye movement recordings with a scleral search coil-eyelid protection device allows new applications
    Andreas Sprenger
    Department of Neurology, University Lübeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    J Neurosci Methods 170:305-9. 2008
  4. doi request reprint The role of prediction and anticipation on age-related effects on smooth pursuit eye movements
    Andreas Sprenger
    Department of Neurology, University of Luebeck, Luebeck, Germany
    Ann N Y Acad Sci 1233:168-76. 2011
  5. doi request reprint Eye movements during REM sleep and imagination of visual scenes
    Andreas Sprenger
    Department of Neurology, University Lübeck, Ratzeburger Allee, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    Neuroreport 21:45-9. 2010
  6. ncbi request reprint Parametric modulation of cortical activation during smooth pursuit with and without target blanking. an fMRI study
    Matthias Nagel
    Department of Psychiatry and Psychotherapy, University of Luebeck, Luebeck, Germany
    Neuroimage 29:1319-25. 2006
  7. doi request reprint On why left events are the right ones: neural mechanisms underlying the left-hemifield advantage in rapid serial visual presentation
    Rolf Verleger
    University Lübeck, Lubeck, Germany
    J Cogn Neurosci 21:474-88. 2009
  8. doi request reprint Sleep is required for improving reaction times after training on a procedural visuo-motor task
    Steffen Gais
    Department of Neuroendocrinology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Neurobiol Learn Mem 90:610-5. 2008
  9. doi request reprint Role of anticipation and prediction in smooth pursuit eye movement control in Parkinson's disease
    Christoph Helmchen
    Department of Neurology, University Hospitals Schleswig Holstein, University of Lubeck, Ratzeburger Allee 160, Lubeck, Germany
    Mov Disord 27:1012-8. 2012
  10. doi request reprint Visual search disorders beyond pure sensory failure in patients with acute homonymous visual field defects
    Björn Machner
    Department of Neurology, University Lübeck, D 23538 Lubeck, Germany
    Neuropsychologia 47:2704-11. 2009

Collaborators

Detail Information

Publications37

  1. doi request reprint Enhanced top-down control during pursuit eye tracking in schizophrenia
    Andreas Sprenger
    Department of Neurology, University Luebeck, Luebeck, Germany
    Eur Arch Psychiatry Clin Neurosci 263:223-31. 2013
    ..This implies that disruption in extrastriate and sensorimotor systems rather than frontostriatal predictive mechanisms may underlie this widely reported endophenotypes for schizophrenia...
  2. pmc Distributed representations of the "preparatory set" in the frontal oculomotor system: a TMS study
    M Nagel
    Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, Luebeck, Germany
    BMC Neurosci 9:89. 2008
    ..This preparatory activity can be examined using the gap-paradigm in which a temporal gap is introduced between the disappearance of a central fixation target and the appearance of an eccentric target...
  3. doi request reprint Long-term eye movement recordings with a scleral search coil-eyelid protection device allows new applications
    Andreas Sprenger
    Department of Neurology, University Lübeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    J Neurosci Methods 170:305-9. 2008
    ..This advanced method allows new applications like eye movement recordings during sleep (rapid eye movements) or perceptional or motor learning tasks, e.g. saccade adaptation paradigms...
  4. doi request reprint The role of prediction and anticipation on age-related effects on smooth pursuit eye movements
    Andreas Sprenger
    Department of Neurology, University of Luebeck, Luebeck, Germany
    Ann N Y Acad Sci 1233:168-76. 2011
    ....
  5. doi request reprint Eye movements during REM sleep and imagination of visual scenes
    Andreas Sprenger
    Department of Neurology, University Lübeck, Ratzeburger Allee, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    Neuroreport 21:45-9. 2010
    ..Thus, REMs may be related to exploratory saccadic behaviour in the awake to remember visual stimuli...
  6. ncbi request reprint Parametric modulation of cortical activation during smooth pursuit with and without target blanking. an fMRI study
    Matthias Nagel
    Department of Psychiatry and Psychotherapy, University of Luebeck, Luebeck, Germany
    Neuroimage 29:1319-25. 2006
    ..Furthermore, we suggest that parietal areas are related to the suppression of saccades during smooth pursuit...
  7. doi request reprint On why left events are the right ones: neural mechanisms underlying the left-hemifield advantage in rapid serial visual presentation
    Rolf Verleger
    University Lübeck, Lubeck, Germany
    J Cogn Neurosci 21:474-88. 2009
    ....
  8. doi request reprint Sleep is required for improving reaction times after training on a procedural visuo-motor task
    Steffen Gais
    Department of Neuroendocrinology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Neurobiol Learn Mem 90:610-5. 2008
    ..During the following sleep period, these changes in turn bring about overt performance improvements, presuming a learning effect based on synaptic tagging...
  9. doi request reprint Role of anticipation and prediction in smooth pursuit eye movement control in Parkinson's disease
    Christoph Helmchen
    Department of Neurology, University Hospitals Schleswig Holstein, University of Lubeck, Ratzeburger Allee 160, Lubeck, Germany
    Mov Disord 27:1012-8. 2012
    ..This may explain the clinical advantage of medical devices that use visual motion to improve gait initiation (e.g., "PD glasses")...
  10. doi request reprint Visual search disorders beyond pure sensory failure in patients with acute homonymous visual field defects
    Björn Machner
    Department of Neurology, University Lübeck, D 23538 Lubeck, Germany
    Neuropsychologia 47:2704-11. 2009
    ..It might either result from disconnections of the primary visual cortex to associated occipital and temporal brain areas or reflect an early stage of compensatory eye movements which differ from chronic HVFD patients...
  11. doi request reprint Cortical mechanisms of retinal and extraretinal smooth pursuit eye movements to different target velocities
    Matthias Nagel
    Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Neuroimage 41:483-92. 2008
    ..The activation of the inferior parietal cortex seems to be related to the interaction between velocity and blanking thereby underlining its relevance for task switching and sensorimotor transformation...
  12. ncbi request reprint Eye-hand coordination in essential tremor
    Peter Trillenberg
    Department of Neurology, University Hospital of Schleswig Holstein, Lubeck, Germany
    Mov Disord 21:373-9. 2006
    ..These changes might be related to cerebellar disease but they are independent of the intention tremor component and saccade performance...
  13. ncbi request reprint Evidence from increased anticipation of predictive saccades for a dysfunction of fronto-striatal circuits in obsessive-compulsive disorder
    Dietmar Spengler
    Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Psychiatry Res 143:77-88. 2006
    ..Furthermore, the cortical network for smooth pursuit (especially the frontal eye field) is also assumed to be disturbed in schizophrenia...
  14. ncbi request reprint Different extraretinal neuronal mechanisms of smooth pursuit eye movements in schizophrenia: An fMRI study
    Matthias Nagel
    Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Neuroimage 34:300-9. 2007
    ..The results implicate that schizophrenic patients employ different strategies during SPEM both with and without target blanking than healthy subjects. These strategies predominantly involve extraretinal mechanisms...
  15. ncbi request reprint A TMS study on non-consciously triggered response tendencies in the motor cortex
    Rolf Verleger
    Department of Neurology, University of Lubeck, 23538, Lubeck, Germany
    Exp Brain Res 173:115-29. 2006
    ..We propose that the left M1 is activated for preparation of both right- and left-hand movements, and we relate the present results to current hypotheses about the nature of inverse priming...
  16. ncbi request reprint Differential effects of sleep deprivation on saccadic eye movements
    Elisabeth Zils
    Department of Neurology, University of Lubeck, Germany
    Sleep 28:1109-15. 2005
    ..This study was designed to show the influence of sleep deprivation on different types of saccadic eye movements...
  17. doi request reprint Hippocampal gray matter volume in bilateral vestibular failure
    Martin Göttlich
    Department of Neurology, University of Lübeck and University Hospital Schleswig Holstein, Lubeck, Germany
    Hum Brain Mapp 37:1998-2006. 2016
    ..Accordingly, hippocampus atrophy and deficits in spatial navigation occur possibly less frequently than previously suspected. Hum Brain Mapp 37:1998-2006, 2016. © 2016 Wiley Periodicals, Inc. ..
  18. ncbi request reprint Visual and non-visual motion information processing during pursuit eye tracking in schizophrenia and bipolar disorder
    Peter Trillenberg
    Department of Neurology, University of Lubeck, Lubeck, Germany
    Eur Arch Psychiatry Clin Neurosci . 2016
    ..More generally, this deficit might reflect a fundamental imbalance between processing external input and acting according to internal preferences...
  19. pmc Deprivation and Recovery of Sleep in Succession Enhances Reflexive Motor Behavior
    Andreas Sprenger
    Department of Neurology, University Luebeck, D 23538 Luebeck, Germany
    Cereb Cortex 25:4610-8. 2015
    ..Our findings indicate that recovery sleep can consolidate motor disinhibition for behaviors practiced during prior sleep deprivation, thereby persistently enhancing response automatization. ..
  20. ncbi request reprint Cortical mechanisms of smooth pursuit eye movements with target blanking. An fMRI study
    Rebekka Lencer
    Department of Psychiatry and Psychotherapy, University of Leubeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Eur J Neurosci 19:1430-6. 2004
    ....
  21. doi request reprint Impact of dynamic bottom-up features and top-down control on the visual exploration of moving real-world scenes in hemispatial neglect
    Björn Machner
    Department of Neurology, University of Lubeck, Lubeck, Germany
    Neuropsychologia 50:2415-25. 2012
    ..Taking into account the lack of top-down control in neglect patients, bottom-up stimulation with moving real-world stimuli may be a promising candidate for future neglect rehabilitation schemes...
  22. ncbi request reprint Cerebellar infarction affects visual search
    Björn Machner
    Department of Neurology, University Lübeck, Lubeck, Germany
    Neuroreport 16:1507-11. 2005
    ....
  23. ncbi request reprint Reduced neuronal activity in the V5 complex underlies smooth-pursuit deficit in schizophrenia: evidence from an fMRI study
    Rebekka Lencer
    Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Neuroimage 24:1256-9. 2005
    ....
  24. pmc Altered velocity processing in schizophrenia during pursuit eye tracking
    Matthias Nagel
    Department of Psychiatry and Psychotherapy, University of Luebeck, Luebeck, Germany
    PLoS ONE 7:e38494. 2012
    ..Cerebellar regions seem to be involved in compensatory mechanisms although cerebellar activity in patients was not related to target velocity...
  25. ncbi request reprint The role of the fastigial nucleus in saccadic eye oscillations
    Christoph Helmchen
    Department of Neurology, University of Lubeck, Lubeck, Germany
    Ann N Y Acad Sci 1004:229-40. 2003
    ..We propose that cerebellar activation of the fastigial nuclei may cause opsoclonus via their projections to the brainstem saccadic generator...
  26. doi request reprint Why do patients with impaired vergence not show "saccadic" vergence?
    Holger Rambold
    Department of Neurology, University of Luebeck, Luebeck, Germany
    Ann N Y Acad Sci 1164:440-3. 2009
    ..Results show that vergence to a step and a ramp stimulus is additive in the step-ramp paradigm, indicating no interaction of both components...
  27. doi request reprint The platelet-rich plasma clot: a standardized in-vitro clot formation protocol for investigations of sonothrombolysis under physiological flows
    Florian C Roessler
    Department of Neurology, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, Lubeck, Germany
    Blood Coagul Fibrinolysis 22:407-15. 2011
    ..Measuring the lysis rate by weighing seems to be inaccurate, with lowest variability in PRP clots. PRP clots appeared more resistant to lysis. PRP clots should be used for standardized sonothrombolysis investigations...
  28. doi request reprint Visual search disorders in acute and chronic homonymous hemianopia: lesion effects and adaptive strategies
    Björn Machner
    Department of Neurology, University of Lubeck, Lubeck, Germamy
    Ann N Y Acad Sci 1164:419-26. 2009
    ..We provide some evidence for adaptive eye-movement strategies developed over time. These adaptive strategies make the visual search more efficient and may help to compensate for the persisting visual-field loss...
  29. ncbi request reprint Effect of 3,4-diaminopyridine on the postural control in patients with downbeat nystagmus
    Andreas Sprenger
    Department of Neurology, University of Lubeck, Germany
    Ann N Y Acad Sci 1039:395-403. 2005
    ..It was concluded that 3,4-DAP may particularly influence the postural performance in patients with downbeat nystagmus...
  30. pmc Postural Ataxia in Cerebellar Downbeat Nystagmus: Its Relation to Visual, Proprioceptive and Vestibular Signals and Cerebellar Atrophy
    Christoph Helmchen
    Department of Neurology, University of Lubeck, Lubeck, Germany
    PLoS ONE 12:e0168808. 2017
    ..The cerebellum integrates proprioceptive, vestibular and visual signals for postural control. Cerebellar patients with downbeat nystagmus (DBN) complain of unsteadiness of stance and gait as well as blurred vision and oscillopsia...
  31. doi request reprint Changes in resting-state fMRI in vestibular neuritis
    Christoph Helmchen
    Department of Neurology, University of Lübeck and University Hospital Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, 23538, Lubeck, Germany
    Brain Struct Funct 219:1889-900. 2014
    ..This may indicate powerful restitution-related or compensatory cortical changes in resting-state activity. ..
  32. pmc Altered resting-state functional connectivity in patients with chronic bilateral vestibular failure
    Martin Göttlich
    Department of Neurology, University of Lubeck, Ratzeburger Allee 160, Lubeck 23538, Germany
    Neuroimage Clin 4:488-99. 2014
    ..The relation of increasing connectivity in the inferior parietal lobe, specifically SMG, to improvement of VOR during active head movements reflects cortical plasticity in BVF and may play a clinical role in vestibular rehabilitation. ..
  33. pmc Ganzfeld stimulation or sleep enhance long term motor memory consolidation compared to normal viewing in saccadic adaptation paradigm
    Caroline Voges
    Department of Neurology, University Luebeck, Luebeck, Germany
    PLoS ONE 10:e0123831. 2015
    ..g., efference copy or prediction to remap their internal representations of saccade targets, thus leading to better consolidation of saccadic adaptation. ..
  34. ncbi request reprint Blink effect on slow vergence
    Holger Rambold
    Department of Neurology, University of Luebeck, Ratzeburger Allee 160, D 23538 Luebeck, Germany
    Neuroreport 13:2041-4. 2002
    ..We propose that the direction-specific blink effect on slow vergence may be caused by changes in brain stem premotor circuits...
  35. pmc Itch relief by mirror scratching. A psychophysical study
    Christoph Helmchen
    Department of Neurology, University of Luebeck, Luebeck, Germany
    PLoS ONE 8:e82756. 2013
    ....
  36. ncbi request reprint Localization of human intraparietal areas AIP, CIP, and LIP using surface orientation and saccadic eye movement tasks
    Elisa Shikata
    NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Germany
    Hum Brain Mapp 29:411-21. 2008
    ....
  37. pmc Effects of second-generation antipsychotic medication on smooth pursuit performance in antipsychotic-naive schizophrenia
    Rebekka Lencer
    Department of Psychiatry, University of Lubeck, Lubeck, Germany
    Arch Gen Psychiatry 65:1146-54. 2008
    ..Although pursuit eye tracking deficits have been widely reported in schizophrenia, the integrity of discrete components of pursuit responses and the effect of second-generation antipsychotic medication on them are not well established...