- Significance of the biopharmaceutical properties of tramadol sustained-release formulations for chrono-pharmacologically optimized treatment of pain from various sourcesA Warnke
SocraTec R and D GmbH, Oberursel, Germany
Int J Clin Pharmacol Ther 47:405-12. 2009..Tramadol is currently one of the most frequently used opioid analgesics in the world...
- [Importance of the formulation for a chronopharmacologically optimised way of pain therapy. Results of a comparative bioavailability study of tramadol extended-release capsules after single-dose evening versus morning administration]A Warnke
SocraTec R and D GmbH, Oberursel
MMW Fortschr Med 150:36-42. 2008..Objective of this study was to investigate the rate and extent of tramadol bioavailability following evening versus morning administration...