- Use and limitations of modular metabolic control analysis in medicine and biotechnologyS Schuster
Max Delbruck Center for Molecular Medicine, Department of Bioinformatics, Berlin Buch, Germany
Metab Eng 1:232-42. 1999..Further limitations such as the restriction to stationary states, uncertainties due to spatial heterogeneities and the impact of experimental error are discussed...
- Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineeringS Schuster
Department of Bioinformatics, Max Delbruck Centre for Molecular Medicine, Berlin Buch, Germany
Trends Biotechnol 17:53-60. 1999..This approach can be used for many biotechnological applications such as increasing the yield of a product, channelling a product into desired pathways and in functional reconstruction from genomic data...
- Calculating activation energies for temperature compensation in circadian rhythmsC Bodenstein
Department of Bioinformatics, Friedrich Schiller University Jena, Ernst Abbe Platz 2, D 07743 Jena, Germany
Phys Biol 8:056007. 2011..We use this approach to analyse different circadian clock models proposed in the literature and calculate activation energies that lead to temperature compensation...
- Cellular information transfer regarded from a stoichiometry and control analysis perspectiveS Schuster
Department of Bioinformatics, Max Delbruck Center for Molecular Medicine, D 13092, Berlin Buch, Germany
Biosystems 55:73-81. 2000....