- Dysregulation of protein kinase C activity in chemoresistant metastatic breast cancer cellsThomas Schondorf
Department of Natural Sciences, University of Applied Sciences, Rheinbach, Germany
Anticancer Drugs 15:265-8. 2004..In order to achieve clinical value, evaluation of more data concerning the PKC signal-transduction pathway is necessary. New protocols of cancer treatment will require this information in order to be successful...
- The V109G polymorphism of the p27 gene CDKN1B indicates a worse outcome in node-negative breast cancer patientsThomas Schondorf
Department of Natural Sciences, University of Applied Sciences Bonn Rhein Sieg, DE 53359 Rheinbach, Germany
Tumour Biol 25:306-12. 2004..In conclusion, the determination of the CDKN1B genotype might be a powerful tool for the prognosis of patients with early breast cancer...
- Hypermethylation of the PTEN gene in ovarian cancer cell linesThomas Schondorf
Department of Natural Sciences, University of Applied Sciences, Augustin, Germany
Cancer Lett 207:215-20. 2004..5%). The data suggest that PTEN is highly regulated at translational level. However, methylation of the PTEN gene plays a subordinate role in ovarian cancer...