A Schnuch

Summary

Country: Germany

Publications

  1. ncbi request reprint White petrolatum (Ph. Eur.) is virtually non-sensitizing. Analysis of IVDK data on 80 000 patients tested between 1992 and 2004 and short discussion of identification and designation of allergens
    Axel Schnuch
    Zentrale des IVDK, Institut an der Universität Göttingen, Gottingen, Germany
    Contact Dermatitis 54:338-43. 2006
  2. doi request reprint Surveillance of contact allergies: methods and results of the Information Network of Departments of Dermatology (IVDK)
    A Schnuch
    Information Network of Departments of Dermatology, University of Gottingen, Gottingen, Germany
    Allergy 67:847-57. 2012
  3. doi request reprint Quantitative patch and repeated open application testing in hydroxyisohexyl 3-cyclohexene carboxaldehyde sensitive-patients
    Axel Schnuch
    Information Network of Departments of Dermatology, University of Gottingen, Göttingen Germany
    Contact Dermatitis 61:152-62. 2009
  4. ncbi request reprint The biocide polyhexamethylene biguanide remains an uncommon contact allergen
    Axel Schnuch
    Information Network of Departments of Dermatology IVDK, University of Gottingen, Germany
    Contact Dermatitis 56:235-9. 2007
  5. ncbi request reprint Contact allergy to fragrances: frequencies of sensitization from 1996 to 2002. Results of the IVDK*
    Axel Schnuch
    Information Network of Department of Dermatology IVDK, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 50:65-76. 2004
  6. ncbi request reprint Sensitization to 26 fragrances to be labelled according to current European regulation. Results of the IVDK and review of the literature
    Axel Schnuch
    Zentrale des IVDK, Institut an der Universität Göttingen, Germany
    Contact Dermatitis 57:1-10. 2007
  7. ncbi request reprint Majantol--a new important fragrance allergen
    Axel Schnuch
    Information Network of Departments of Dermatology IVDK, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 57:48-50. 2007
  8. ncbi request reprint A further characteristic of susceptibility to contact allergy: sensitization to a weak contact allergen is associated with polysensitization. Results of the IVDK
    Axel Schnuch
    Information Network of Departments of Dermatology IVDK, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 56:331-7. 2007
  9. doi request reprint para-Phenylenediamine: the profile of an important allergen. Results of the IVDK
    A Schnuch
    Department of Dermatology, University of Witten Herdecke and Klinikum Dortmund gGmbH, Dortmund, Germany
    Br J Dermatol 159:379-86. 2008
  10. ncbi request reprint Decrease in nickel allergy in Germany and regulatory interventions
    A Schnuch
    IVDK Center at the Georg August University, Gottingen, Germany
    Contact Dermatitis 49:107-8. 2003

Detail Information

Publications85

  1. ncbi request reprint White petrolatum (Ph. Eur.) is virtually non-sensitizing. Analysis of IVDK data on 80 000 patients tested between 1992 and 2004 and short discussion of identification and designation of allergens
    Axel Schnuch
    Zentrale des IVDK, Institut an der Universität Göttingen, Gottingen, Germany
    Contact Dermatitis 54:338-43. 2006
    ..Sporadic cases of contact allergy to white petrolatum, which is used as a vehicle in patch test preparations, have been reported. The quantitative relevance of the phenomenon remains yet to be elucidated...
  2. doi request reprint Surveillance of contact allergies: methods and results of the Information Network of Departments of Dermatology (IVDK)
    A Schnuch
    Information Network of Departments of Dermatology, University of Gottingen, Gottingen, Germany
    Allergy 67:847-57. 2012
    ..National prescription data of drugs and statistics of labelling of preservatives on cosmetics can be included, the latter two approaches allowing for risk estimates conferred by specific allergens...
  3. doi request reprint Quantitative patch and repeated open application testing in hydroxyisohexyl 3-cyclohexene carboxaldehyde sensitive-patients
    Axel Schnuch
    Information Network of Departments of Dermatology, University of Gottingen, Göttingen Germany
    Contact Dermatitis 61:152-62. 2009
    ..To identify the concentration of the fragrance compound hydroxyisohexyl 3-cyclohexene carboxaldehyde (INCI) (HICC) that is sufficiently low not to cause an allergic reaction in patients with proven sensitization...
  4. ncbi request reprint The biocide polyhexamethylene biguanide remains an uncommon contact allergen
    Axel Schnuch
    Information Network of Departments of Dermatology IVDK, University of Gottingen, Germany
    Contact Dermatitis 56:235-9. 2007
    ..Further risk factors included leg dermatitis and old age. The frequency of sensitization remains low. It is very unlikely that exposure to cosmetics or personal care products may have played a role in the few cases sensitized...
  5. ncbi request reprint Contact allergy to fragrances: frequencies of sensitization from 1996 to 2002. Results of the IVDK*
    Axel Schnuch
    Information Network of Department of Dermatology IVDK, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 50:65-76. 2004
    ....
  6. ncbi request reprint Sensitization to 26 fragrances to be labelled according to current European regulation. Results of the IVDK and review of the literature
    Axel Schnuch
    Zentrale des IVDK, Institut an der Universität Göttingen, Germany
    Contact Dermatitis 57:1-10. 2007
    ..3) There are obviously fragrances among the 26 which are, with regard to contact allergy, of great, others of minor, and some of no importance at all...
  7. ncbi request reprint Majantol--a new important fragrance allergen
    Axel Schnuch
    Information Network of Departments of Dermatology IVDK, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 57:48-50. 2007
  8. ncbi request reprint A further characteristic of susceptibility to contact allergy: sensitization to a weak contact allergen is associated with polysensitization. Results of the IVDK
    Axel Schnuch
    Information Network of Departments of Dermatology IVDK, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 56:331-7. 2007
    ..PS can be regarded as a phenotype to be considered in genetic studies...
  9. doi request reprint para-Phenylenediamine: the profile of an important allergen. Results of the IVDK
    A Schnuch
    Department of Dermatology, University of Witten Herdecke and Klinikum Dortmund gGmbH, Dortmund, Germany
    Br J Dermatol 159:379-86. 2008
    ..para-Phenylenediamine (PPD) is an important contact allergen and primarily used in hair dyeing...
  10. ncbi request reprint Decrease in nickel allergy in Germany and regulatory interventions
    A Schnuch
    IVDK Center at the Georg August University, Gottingen, Germany
    Contact Dermatitis 49:107-8. 2003
  11. doi request reprint [Facial allergic contact dermatitis. Data from the IVDK and review of literature]
    A Schnuch
    Informationsverbund Dermatologischer Kliniken IVDK, Institut an der Universität Göttingen, Siebold Strasse 3, 37075, Gottingen
    Hautarzt 60:13-21. 2009
    ..In the clinical approach to patients with facial dermatitis, occupational airborne causation should be considered in addition to non-occupational (e.g., cosmetic) allergen exposure...
  12. ncbi request reprint [Routine preliminary testing of products with oxidative hair colors before hair coloring presents problems and is refused. Position of the leadership of the German Contact Allergy Group]
    Axel Schnuch
    IVDK Institut an der Universitat Göttingen
    J Dtsch Dermatol Ges 3:700-1. 2005
  13. doi request reprint Experimental inhalation of fragrance allergens in predisposed subjects: effects on skin and airways
    A Schnuch
    Information Network of Departments of Dermatology, IVDK Zentrale, Institut an der Universität Göttingen, Gottingen, Germany
    Br J Dermatol 162:598-606. 2010
    ..Exposure to fragrances is increasingly encountered in the environment. Some fragrances are known to be important skin and potential airway sensitizers...
  14. ncbi request reprint [Decrease in nickel sensitization in young patients--successful intervention through nickel exposure regulation? Results of IVDK, 1992-2001]
    A Schnuch
    Zentrale des IVDK, Institut an der Georg August Universität Göttingen
    Hautarzt 54:626-32. 2003
    ..In the early 1990s, the prevalence of nickel contact allergy was high-almost 20% on a population level, and some 40% in contact dermatitis patients. Around that time, nickel exposure was starting to be regulated...
  15. doi request reprint Genetic factors in contact allergy--review and future goals
    Axel Schnuch
    Information Network of Departments of Dermatology IVDK, University of Gottingen, D 37075 Gottingen, Germany
    Contact Dermatitis 64:2-23. 2011
    ....
  16. doi request reprint Nickel allergy is still frequent in young German females - probably because of insufficient protection from nickel-releasing objects
    Axel Schnuch
    Information Network of Departments of Dermatology IVDK, University of Gottingen, 37075 Gottingen, Germany
    Contact Dermatitis 64:142-50. 2011
    ..Objectives. To explain this observation by relating clinical epidemiological data with recent chemical analyses of nickel release from costume jewellery...
  17. doi request reprint Contact allergy to preservatives. Analysis of IVDK data 1996-2009
    A Schnuch
    Information Network of Department of Dermatology IVDK, University of Gottingen, Gottingen, Germany
    Br J Dermatol 164:1316-25. 2011
    ..Preservatives are well-known and important contact allergens...
  18. ncbi request reprint When should a substance be designated as sensitizing for the skin ('Sh') or for the airways ('Sa')?
    A Schnuch
    IVDK Institut an der Universitat Göttingen, Germany
    Hum Exp Toxicol 21:439-44. 2002
    ..This paper informs readers working scientifically or administratively in this field and invites a critical discussion of the issue...
  19. ncbi request reprint Epidemiology of contact allergy: an estimation of morbidity employing the clinical epidemiology and drug-utilization research (CE-DUR) approach
    A Schnuch
    Information Network of Departments of Dermatology, Institute at the Georg August Universität Göttingen, Germany
    Contact Dermatitis 47:32-9. 2002
    ..In comparison to these, the CE-DUR approach seems to be an economically feasible method to estimate continuously the population impact of ACD and CS...
  20. doi request reprint Is cocamidopropyl betaine a contact allergen? Analysis of network data and short review of the literature
    Axel Schnuch
    Information Network of Departments of Dermatology, University of Gottingen, von Siebold Strasse 3, Göttingen Germany
    Contact Dermatitis 64:203-11. 2011
    ..There is no general agreement on whether cocamidopropyl betaine (CAPB) is a skin sensitizer...
  21. doi request reprint Risk of sensitization to preservatives estimated on the basis of patch test data and exposure, according to a sample of 3541 leave-on products
    Axel Schnuch
    Information Network of Departments of Dermatology, University of Gottingen, 37075 Gottingen, Germany
    Contact Dermatitis 65:167-74. 2011
    ..The risk of sensitization cannot be derived from the frequency of sensitization to allergens alone, but exposure should be considered...
  22. ncbi request reprint Quantitative patch and repeated open application testing in methyldibromo glutaronitrile-sensitive patients
    A Schnuch
    Information Network of Department of Dermatology IVDK, University of Gottingen, Germany
    Contact Dermatitis 52:197-206. 2005
    ..By contrast, with other contact allergens, dose-response use tests may be able to identify a non-eliciting concentration, which could give valuable clues to a non-inducing (i.e., safe) concentration in products...
  23. ncbi request reprint The preservative iodopropynyl butylcarbamate: frequency of allergic reactions and diagnostic considerations
    A Schnuch
    Center of the Information Network of Departments of Dermatology, Institute at the Georg August Universität Göttingen, Germany
    Contact Dermatitis 46:153-6. 2002
    ..We propose that higher concentrations of IPBC (0.3%) should be evaluated in a study also addressing suitable validation tests like ROAT or PUT...
  24. ncbi request reprint [Do sulfonamides still retain a place in dermatological therapy?]
    A Schnuch
    IVDK Universitäts Hautklinik, von Siebold Strasse 3, 37075 Gottingen
    Hautarzt 53:163-6. 2002
  25. ncbi request reprint [A common and insidious side-effect: allergic contact dermatitis caused by bufexamac used in the treatment of dermatitis. Results from the Information Network of Departments of Dermatology (IDVK)]
    A Schnuch
    Zentrale des IVDK, Institut an der Universität Göttingen, Gottingen
    Dtsch Med Wochenschr 130:2881-6. 2005
    ..In order to estimate the quantitative importance of ACD to bufexamac, data of the Information Network of (German) Departments of Dermatology (IVDK) from July 1999 to December 2004 were analysed...
  26. ncbi request reprint Strong allergic patch test reactions may indicate a general disposition for contact allergy
    J Brasch
    Department of Dermatology, University of Schleswig Holstein, Campus Kiel, Kiel, Germany
    Allergy 61:364-9. 2006
    ..This study evaluates synchronous patch test reactions to test the hypothesis that in such cases an allergen-independent disposition for contact sensitization may be involved...
  27. ncbi request reprint ["When should a substance be designated as sensitizing for the skin ("sh") or for the airways ("sa")"?"]
    A Schnuch
    Institut an der Universität Göttingen, vol Siegold, Gottingen, Germany
    Pneumologie 56:304-8. 2002
  28. pmc Association between occupation and contact allergy to the fragrance mix: a multifactorial analysis of national surveillance data
    W Uter
    Information Network of Departments of Dermatology, Department of Dermatology, Georg August University, von Siebold Strasse 3, D 37075 Gottingen, Germany
    Occup Environ Med 58:392-8. 2001
    ..The role of occupational exposure to fragrances is, however, yet unclear...
  29. ncbi request reprint Iodopropynylbutyl carbamate 0.2% is suggested for patch testing of patients with eczema possibly related to preservatives
    J Brasch
    Department of Dermatology, University of Schleswig Holstein, Kiel, Germany
    Br J Dermatol 151:608-15. 2004
    ..Although cases of allergic contact dermatitis to IPBC have been reported, it is not known whether the usual test concentration of 0.1% is appropriate for screening tests with IPBC...
  30. doi request reprint Polysensitization and increased susceptibility in contact allergy: a review
    A Schnuch
    Center of the Information Network of Department of Dermatology, Institute at University of Göttingen, Gottingen, Germany
    Allergy 63:156-67. 2008
    ..Future studies on the genetics of CA should be performed in subgroups with PS, focussing on polymorphisms relevant for CA-specific and nonspecific (inflammatory) processes...
  31. ncbi request reprint Rosacea and contact allergy to cosmetics and topical medicaments--retrospective analysis of multicentre surveillance data 1995-2002
    U Jappe
    Department of Dermatology, University of Heidelberg, Heidelberg, Germany
    Contact Dermatitis 52:96-101. 2005
    ..Irritant or doubtful patch test reactions were provoked by various substances (vehicles, oxidants and preservatives of various creams), which might also be clinically important, considering the heightened sensitivity of rosaceous skin...
  32. doi request reprint The importance of context information in the diagnostic rating of digital images of patch test reactions
    W Uter
    Department of Dermatology, University of Witten Herdecke and Klinikum Dortmund gGmbH, Dortmund, Germany
    Br J Dermatol 161:554-9. 2009
    ..Patch test (PT) guidelines recommend classifying PT reactions based on morphological criteria only, i.e. irrespective of context information such as substance, concentration and vehicle...
  33. doi request reprint [Clinical epidemiology and prevention of contact allergies. The Information Network of Departments of Dermatology (IVDK) as a register and surveillance system]
    A Schnuch
    Informationsverbund Dermatologischer Kliniken, Universitatsmedizin Gottingen, von Siebold Str 3, 37075, Gottingen, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 55:329-37. 2012
    ..Unfortunately, the (current) national regulatory framework severely hampers clinical surveillance/epidemiology of contact sensitization and, thus, prevention of contact allergy...
  34. ncbi request reprint Associated positive patch test reactions to standard contact allergens
    J Brasch
    Department of Dermatology, University of Kiel, Kiel, Germany
    Am J Contact Dermat 12:197-202. 2001
    ..Patch testing with a standard allergen series often yields positive reactions to more than 1 allergen in a patient...
  35. ncbi request reprint Frequency of sensitization to antimicrobials in patients with atopic eczema compared with nonatopic individuals: analysis of multicentre surveillance data, 1995-1999
    U Jappe
    Department of Dermatology, University of Heidelberg, Vosstrasse 2, D 69115 Heidelberg, Germany
    Br J Dermatol 149:87-93. 2003
    ..Atopic eczema, a multifactorial disease, is influenced by bacterial factors, particularly Staphylococcus aureus. Consequently, treatment includes therapy with antibiotics and nonantibiotic antimicrobials...
  36. doi request reprint Classification of skin sensitizing substances: a comparison between approaches used by the DFG-MAK Commission and the European Union legislation
    H Lessmann
    Information Network of Departments of Dermatology IVDK, University of Gottingen, von Siebold Str 3, 37085 Göttingen, Germany
    Regul Toxicol Pharmacol 61:1-8. 2011
    ..g. carcinogenicity, risks during pregnancy, germ cell mutagenicity or contribution to systemic toxicity after cutaneous absorption. Skin- and airway sensitization is also considered; the present paper focuses on these two endpoints...
  37. doi request reprint Contact allergy in patients with rosacea: a clinic-based, prospective epidemiological study
    U Jappe
    Department of Dermatology, University of Heidelberg, Medical University Schleswig Holstein, Campus Luebeck, Germany
    J Eur Acad Dermatol Venereol 22:1208-14. 2008
    ..Rosacea is a relatively common inflammatory skin disease of unknown prevalence. The proportion of contact allergy complicating rosacea and its therapy, respectively, is largely unknown...
  38. ncbi request reprint Patch testing with phenylmercuric acetate
    J Geier
    Information Network of Departments of Dermatology, University of Gottingen, Germany
    Contact Dermatitis 53:117-8. 2005
  39. ncbi request reprint The profile of patch test reactions to common contact allergens is related to sex
    Jochen Brasch
    Department of Dermatology, University Clinics of Schleswig Holstein, Campus Kiel, D 24105 Kiel, Germany
    Contact Dermatitis 58:37-41. 2008
    ..Women are more often patch tested than men, and the reactivity to patch test allergens is dependent on sex. However, it is unclear whether the profiles of test reactions are also sex-related...
  40. ncbi request reprint Contact allergy to farnesol in 2021 consecutively patch tested patients. Results of the IVDK
    Axel Schnuch
    Information Network of Departments of Dermatology IVDK, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 50:117-21. 2004
    ..We recommend that farnesol should be included in a fragrance patch-test preparation and that its use should be regulated for consumer safety reasons. Furthermore, the extent of exposure to farnesol should be further studied...
  41. doi request reprint Contact allergy to topical antifungal agents
    C A Menezes de Pádua
    Department of Dermatology, Municipal Medical Center of Bielefeld, Academic Teaching Hospital, An der Rosenhöhe 27, D 33647 Bielefeld, Germany
    Allergy 63:946-7. 2008
  42. ncbi request reprint Glyoxal is an important allergen for (medical care) cleaning staff
    W Uter
    Information Network of Departments of Dermatology IVDK, Georg August University, Department of Dermatology, Gottingen, Germany
    Int J Hyg Environ Health 204:251-3. 2001
    ..In conclusion, glyoxal should be tested in all patients with contact dermatitis working in occupations with possible exposure to respective disinfecting/cleaning agents...
  43. ncbi request reprint Contact sensitizations in metalworkers with occupational dermatitis exposed to water-based metalworking fluids: results of the research project "FaSt"
    Johannes Geier
    Informationsverbund Dermatologischer Kliniken, University of Gottingen, von Siebold Strasse 3, 37075 Gottingen, Germany
    Int Arch Occup Environ Health 77:543-51. 2004
    ....
  44. ncbi request reprint Are concomitant patch test reactions to epoxy resin and BIS-GMA indicative of cross-reactivity?
    Johannes Geier
    Information Network of Departments of Dermatology, University of Gottingen, Germany
    Contact Dermatitis 57:376-80. 2007
    ..Despite rare simultaneous exposure, concomitant sensitisation to bisphenol A diglycidyl methacrylate (BIS-GMA) and epoxy resin frequently occurs. Immunological cross-reactivity has not been proven by animal experiments so far...
  45. ncbi request reprint Patch-test reaction patterns in patients with a predisposition to atopic dermatitis
    Jochen Brasch
    Department of Dermatology, University of Schleswig Holstein, Campus Kiel, Schittenhelmstr 7, 24105 Kiel, Germany
    Contact Dermatitis 49:197-201. 2003
    ..In conclusion, standard methods for patch testing can be applied in patients with a predisposition to atopic dermatitis, but minor differences in reaction patterns should be considered...
  46. ncbi request reprint Diagnostic quality of the patch test preparation monoethanolamine 2% pet
    Johannes Geier
    Information Network of Departments of Dermatology, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 52:171-3. 2005
  47. ncbi request reprint A high-positive patch test load correlates with further positive patch test reactions irrespective of their location
    J Brasch
    Department of Dermatology, University Hospitals of Schleswig Holstein, Campus Kiel, Kiel, Germany
    Allergy 61:1411-5. 2006
    ..This article analyses whether there is a distance-related effect of synchronous positive patch test reactions on the outcome of a target patch test...
  48. ncbi request reprint Lyral has been included in the patch test standard series in Germany
    Johannes Geier
    Information Network of Departments of Dermatology IVDK, Georg August University, Germany
    Contact Dermatitis 46:295-7. 2002
    ..8% of those reacting to Lyral. So the concordance of positive test reactions to Lyral and FM was only slight. Based on these results, the German Contact Dermatitis Research Group (DKG) decided to add Lyral 5% pet. to the standard series...
  49. ncbi request reprint Contact sensitization to N-(cyclohexylthio)phthalimide
    Johannes Geier
    Information Network of Departments of Dermatology IVDK, Georg August University, Gottingen, Germany
    Contact Dermatitis 48:1-6. 2003
    ..So the relevance of positive CTP patch test reactions, and the causative exposures in patients with CTP allergy, still remain to be clarified...
  50. ncbi request reprint Occupational rubber glove allergy: results of the Information Network of Departments of Dermatology (IVDK), 1995-2001
    Johannes Geier
    Information Network of Departments of Dermatology, University of Gottingen, Germany
    Contact Dermatitis 48:39-44. 2003
    ..Thioureas and 1,3-DPG are not widely used in rubber glove production, and play only a minor role in rubber glove contact allergy. Most of the positive reactions to 1,3-DPG are probably false-positive, irritant reactions...
  51. ncbi request reprint Patch testing with zinc dibenzyldithiocarbamate. A multicentre study of the Information Network of Departments of Dermatology and the German Contact Dermatitis Research Group
    Johannes Geier
    Information Network of Departments of Dermatology, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 48:209-11. 2003
  52. ncbi request reprint Patch tests with thiurams at 0.25% pet. and 1% pet. are of equal diagnostic value
    Johannes Geier
    Information Network of Department of Dermatology, University of Gottingen, Germany
    Contact Dermatitis 46:258-61. 2002
    ..The sensitivity of the mix also did not change when the breakdown test was performed with 1% pet. instead of 0.25% pet. Thus, we conclude that both concentrations are of equal diagnostic value in patch testing...
  53. ncbi request reprint The positivity ratio--another parameter to assess the diagnostic quality of a patch test preparation
    Johannes Geier
    Information Network of Department of Dermatology IVDK, Georg August University, Gottingen, Germany
    Contact Dermatitis 48:280-2. 2003
  54. ncbi request reprint Diagnostic screening for contact allergy to mercaptobenzothiazole derivatives
    Johannes Geier
    Information Network of Departments of Dermatology, University of Gottingen, Gottingen, Germany
    Am J Contact Dermat 13:66-70. 2002
    ..A previous analysis based on patch test data from 1990 to 1993 has shown that the mercapto mix lacked sensitivity. Chemical analyses on the stability of the mix components led to a new composition of the mix in 1995...
  55. ncbi request reprint Patch testing with components of water-based metalworking fluids
    Johannes Geier
    Informationsverbund Dermatologischer Kliniken, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 49:85-90. 2003
    ..The lack of positive test reactions to the other MWF components tested may be due to their low-sensitizing potential or too low a patch test concentration being used...
  56. ncbi request reprint Patch test results with the metalworking fluid series of the German Contact Dermatitis Research Group (DKG)
    Johannes Geier
    Information Network of Departments of Dermatology, University of Gottingen, Germany
    Contact Dermatitis 51:118-30. 2004
    ..The test series with current MWF allergens has to be kept up-to-date based on information from industry and to be kept concise by eliminating test substances which never cause positive reactions...
  57. ncbi request reprint Allergic contact dermatitis due to beta-blockers in eye drops: a retrospective analysis of multicentre surveillance data 1993-2004
    Uta Jappe
    Department of Dermatology, University of Heidelberg, Germany
    Acta Derm Venereol 86:509-14. 2006
    ....
  58. ncbi request reprint Skin-sensitizing and irritant properties of propylene glycol
    Holger Lessmann
    Information Network of Departments of Dermatology IVDK, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 53:247-59. 2005
    ..Therefore, according to our patch test data, PG seems to exhibit very low sensitization potential, and the risk for sensitization to PG on uncompromised skin seems to be very low...
  59. ncbi request reprint An attempt to improve diagnostics of contact allergy due to epoxy resin systems. First results of the multicentre study EPOX 2002
    Johannes Geier
    Information Network of Departments of Dermatology IVDK, University of Gottingen, 37075 Gottingen, Germany
    Contact Dermatitis 51:263-72. 2004
    ..8%), followed by isophorone diamine (5.7%). No reactions were observed to several substances, the test concentration of which may have been too low and will be increased in the future...
  60. doi request reprint Presumptive frequency of, and review of reports on, allergies to household gloves
    E Proksch
    Department of Dermatology, University of Kiel, Germany
    J Eur Acad Dermatol Venereol 23:388-93. 2009
    ..In contrast, very few articles have reported on latex allergy (type I) or allergic contact sensitization to additives (type IV) associated with household gloves, in spite of some 44 million pairs sold in Germany in, e.g., 2006...
  61. ncbi request reprint The prevalence of contact allergy differed between population-based and clinic-based data
    Wolfgang Uter
    Information Network of Departments of Dermatology, University of Gottingen, Germany
    J Clin Epidemiol 57:627-32. 2004
    ..Epidemiologic evidence on contact allergy (CA) largely relies on clinical studies. However, the effects of the selection process until consultation as patient are largely unclear...
  62. ncbi request reprint Association of allergic contact dermatitis with a promoter polymorphism in the IL16 gene
    Kristian Reich
    Department of Dermatology, Georg August University, Gottingen, Germany
    J Allergy Clin Immunol 112:1191-4. 2003
    ....
  63. doi request reprint Patch testing with benzoyl peroxide: reaction profile and interpretation of positive patch test reactions
    Hans Michael Ockenfels
    Department of Dermatology, Klinikum Hanau, 63450 Hanau, Germany
    Contact Dermatitis 61:209-16. 2009
    ..Patch testing with benzoyl peroxide 1% pet. frequently leads to (weak) positive reactions, often with uncertain clinical relevance...
  64. doi request reprint Contact sensitization in patients with suspected cosmetic intolerance: results of the IVDK 2006-2011
    A Dinkloh
    Department of Dermatology, Venereology and Allergy, Charite Universitatsmedizin, Berlin, Germany
    J Eur Acad Dermatol Venereol 29:1071-81. 2015
    ..Ingredients of leave-on cosmetics and body care products may sensitize. However, not every case of cosmetic intolerance is due to contact sensitization...
  65. ncbi request reprint Patch testing with p-toluene diamine preparations of different ages
    Johannes Geier
    Information Network of Departments of Dermatology, University of Gottingen, Gottingen, Germany
    Contact Dermatitis 53:75-9. 2005
    ..The chemical reactions mentioned above apparently do not affect the diagnostic quality of PTD patch test preparations because the true allergen probably is not PTD itself, but one or more of the reaction products...
  66. ncbi request reprint Cytokine gene polymorphisms in allergic contact dermatitis
    Götz A Westphal
    Department of Occupational Health, Georg August University, Gottingen, Germany
    Contact Dermatitis 48:93-8. 2003
    ..These findings suggest a possible relationship between the TNFA-308 polymorphism and contact allergy. The results need to be confirmed in future studies...
  67. ncbi request reprint Patch testing in children--recommendations of the German Contact Dermatitis Research Group (DKG)
    Margitta Worm
    Department of Dermatology and Allergy, Charite, Berlin, Germany
    J Dtsch Dermatol Ges 5:107-9. 2007
    ..Standardized patch testing makes it possible to systematically investigate allergic contact dermatitis and identify relevant allergens in children...
  68. ncbi request reprint The concentration of para-phenylenediamine (PPD) for routine patch testing in a standard series needs to be redefined
    Detlef Becker
    Contact Dermatitis 53:186-7. 2005
  69. ncbi request reprint Clinical update on contact allergy
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nuremberg, Erlangen, Germany
    Curr Opin Allergy Clin Immunol 5:429-36. 2005
    ..The aim of this article is to review recent findings in contact allergy, regarding clinical research...
  70. ncbi request reprint Frequency of contact allergy in German children and adolescents patch tested between 1995 and 2002: results from the Information Network of Departments of Dermatology and the German Contact Dermatitis Research Group
    Guido Heine
    Klinik fur Dermatologie, Venerologie und Allergologie, Campus Charite Mitte, Universitatsmedizin, Berlin, Germany
    Contact Dermatitis 51:111-7. 2004
    ..Atopy-related diseases were more common in children compared to adults. On the basis of the data of this study, the relationship between atopy and the risk of development of ACD, at least in children, needs further investigation...
  71. ncbi request reprint Patch testing with patients' own cosmetics and toiletries--results of the IVDK*, 1998-2002
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nurnberg, Erlangen, Germany
    Contact Dermatitis 53:226-33. 2005
    ..In conclusion, testing of patients' own products can be regarded as efficient and safe, if in accordance with current recommendations...
  72. ncbi request reprint Guidelines for the descriptive presentation and statistical analysis of contact allergy data
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nurnberg, Erlangen, Germany
    Contact Dermatitis 51:47-56. 2004
    ..With increasing complexity of statistical description and analysis, consulting with a biostatistician is often mandatory...
  73. ncbi request reprint Isopropyl myristate recommended for aimed rather than routine patch testing
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology IMBE, University of Erlangen Nurnberg, Wakdstrasse 6, D 91054 Erlangen, Germany
    Contact Dermatitis 50:242-4. 2004
    ..g. to cosmetics and perfumes, to avoid an unacceptable reduction of the positive predictive value of the test...
  74. ncbi request reprint Is contact allergy to glyceryl monothioglycolate still a problem in Germany?
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nurnberg, Erlangen, Germany
    Contact Dermatitis 55:54-6. 2006
  75. ncbi request reprint Contact allergy in construction workers: results of a multifactorial analysis
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, Friedrich Alexander University Erlangen Nurnberg, Waldstrasse 6, 91054 Erlangen, Germany
    Ann Occup Hyg 48:21-7. 2004
    ....
  76. ncbi request reprint Contact allergy to ingredients of hair cosmetics in female hairdressers and clients--an 8-year analysis of IVDK data
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nurnberg, Erlangen, Germany
    Contact Dermatitis 49:236-40. 2003
    ..7% to 16.7%). A slighter increase was also noted with ammonium persulfate in C (3.1-6.8%), while the proportion of H sensitized remained largely constant at about 26%...
  77. ncbi request reprint Current patch test results in consecutive patients with, and chemical analysis of, disperse blue (DB) 106, DB 124, and the mix of DB 106 and 124
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nurnberg, Erlangen, Germany
    Contact Dermatitis 57:230-4. 2007
    ..Quality control, providing accurate test concentrations of allergens based on technical grade purity raw materials is necessary for valid diagnosis of contact allergy and comparable epidemiological data...
  78. ncbi request reprint 10-year prevalence of contact allergy in the general population in Denmark estimated through the CE-DUR method
    Jacob Pontoppidan Thyssen
    National Allergy Research Centre, Department of Dermatology, Gentofte University Hospital, 1 2820 Gentofte, Denmark
    Contact Dermatitis 57:265-72. 2007
    ..This could probably be explained by a decrease in nickel allergy. The CE-DUR approach holds the potential of being an efficient and easy monitoring method of contact allergy prevalence...
  79. doi request reprint Changes of the patch test population (MOAHLFA index) in long-term participants of the Information Network of Departments of Dermatology, 1999-2006
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nurnberg, D 91054 Erlangen, Germany
    Contact Dermatitis 59:56-7. 2008
  80. doi request reprint Patch test results with metals and meteorological conditions
    Janice Hegewald
    Department of Medical Informatics, Biometry and Epidemiology, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Int Arch Allergy Immunol 147:235-40. 2008
    ..We aimed to investigate how patch test reactions to these metals relate to outdoor temperature and humidity at the time of testing...
  81. ncbi request reprint The validity of rating patch test reactions based on digital images
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nurnberg, Erlangen, Germany
    Contact Dermatitis 57:337-42. 2007
    ..The proper reading of patch test (PT) reactions, based on morphological criteria, is of utmost importance. Digital images are increasingly used for medical training...
  82. ncbi request reprint Contact allergy to hairdressing allergens in female hairdressers and clients--current data from the IVDK, 2003-2006
    Wolfgang Uter
    Institute for Medical Information Technology, Biometry and Epidemiology, University of Erlangen Nuremberg, Erlangen, Germany
    J Dtsch Dermatol Ges 5:993-1001. 2007
    ..Hair cosmetics, in particular hair dyes, bleaches, and permanent wave solutions, contain a number of potential contact allergens. The pattern of exposure to these in hairdressers, clients and home-users may change over time...
  83. doi request reprint Is the irritant benzalkonium chloride a contact allergen? A contribution to the ongoing debate from a clinical perspective
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nurnberg, D 91054 Erlangen, Germany
    Contact Dermatitis 58:359-63. 2008
    ..Benzalkonium chloride (BAC) is a well-recognized irritant. However, doubts exist that it is also a contact allergen...
  84. ncbi request reprint Aniline--a 'historical' contact allergen? Current data from the IVDK and review of the literature
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, Friedrich Alexander University Erlangen Nürnberg Erlangen, Germany
    Ann Occup Hyg 51:219-26. 2007
    ..To assess whether aniline should be regarded as potential cause of contact allergy (CA)...
  85. ncbi request reprint A multilingual European patch test software concept: WinAlldat/ESSCA
    Wolfgang Uter
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen Nurnberg, Germany
    Contact Dermatitis 49:270-1. 2003