K J Schmitz

Summary

Country: Germany

Publications

  1. pmc Intramural carcinoma of the oesophagogastric junction
    Klaus Jürgen Schmitz
    Pathologisches Institut, Recklinghausen, Recklinghausen, Germany
    BMJ Case Rep 2012:. 2012
  2. pmc Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status
    Klaus Juergen Schmitz
    Institute of Pathology, Mühlenstrasse 31, 45659, Recklinghausen, Germany
    World J Surg Oncol 14:189. 2016
  3. pmc Increased expression of α-methylacyl-coenzyme A racemase (AMACR; p504s) and p16 in distal hyperplastic polyps
    Nimet Dayi
    Institute of Pathology and Neuropathology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Diagn Pathol 8:178. 2013
  4. doi request reprint [Pathological work-up of rectal cancer following partial/total mesorectal excision]
    K J Schmitz
    Institut für Pathologie und Neuropathologie, Universitatsklinikum Essen, Universitat Duisburg Essen, Essen, Deutschland
    Pathologe 32:321-9. 2011
  5. doi request reprint [Space-occupying lesion of the ribs]
    K J Schmitz
    Pathologisches Institut Recklinghausen, Mühlenstraße 31, 45659, Recklinghausen, Deutschland
    Pathologe 33:350-1. 2012
  6. pmc Overexpression of cyclo-oxygenase-2 is an independent predictor of unfavourable outcome in node-negative breast cancer, but is not associated with protein kinase B (Akt) and mitogen-activated protein kinase (ERK1/2, p38) activation or with Her-2/neu signa
    K J Schmitz
    Institute of Pathology, University Hospital of Essen, Germany
    J Clin Pathol 59:685-91. 2006
  7. doi request reprint Cyclo-oxygenase-2 overexpression is a feature of early and well-differentiated hepatocellular carcinoma with a favourable prognosis
    K J Schmitz
    Institute of Pathology and Neuropathology, University Hospital Essen, University of Duisburg Essen, Hufelandstrasse 55, Essen 45122, Germany
    J Clin Pathol 62:690-3. 2009
  8. ncbi request reprint Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations
    K J Schmitz
    Institute of Pathology and Neuropathology, University Hospital of Essen, Hufelandstr 55, 45122 Essen, Germany
    Virchows Arch 450:151-9. 2007
  9. doi request reprint "Preemptive" live donor liver transplantation for fibrolamellar hepatocellular carcinoma: a case report
    I Fouzas
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3806-7. 2008
  10. pmc AKT and ERK1/2 signaling in intrahepatic cholangiocarcinoma
    K J Schmitz
    Institute of Pathology and Neuropathology, University Hospital of Essen, University Duisburg Essen, Germany
    World J Gastroenterol 13:6470-7. 2007

Collaborators

Detail Information

Publications15

  1. pmc Intramural carcinoma of the oesophagogastric junction
    Klaus Jürgen Schmitz
    Pathologisches Institut, Recklinghausen, Recklinghausen, Germany
    BMJ Case Rep 2012:. 2012
    ..Intramural carcinomas are a diagnostic challenge for clinicians and pathologist, since preoperative biopsies mostly fail to establish the diagnosis and surgical explorations must be considered...
  2. pmc Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status
    Klaus Juergen Schmitz
    Institute of Pathology, Mühlenstrasse 31, 45659, Recklinghausen, Germany
    World J Surg Oncol 14:189. 2016
    ..Here we investigated the potential prognostic value of the autophagy-related proteins Beclin-1, p62, LC3 and uncoordinated (UNC) 51-like kinase 1 (ULK1) in a cohort of colorectal cancer (CRC) specimens...
  3. pmc Increased expression of α-methylacyl-coenzyme A racemase (AMACR; p504s) and p16 in distal hyperplastic polyps
    Nimet Dayi
    Institute of Pathology and Neuropathology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Diagn Pathol 8:178. 2013
    ....
  4. doi request reprint [Pathological work-up of rectal cancer following partial/total mesorectal excision]
    K J Schmitz
    Institut für Pathologie und Neuropathologie, Universitatsklinikum Essen, Universitat Duisburg Essen, Essen, Deutschland
    Pathologe 32:321-9. 2011
    ..In addition, particular issues relating to margins, lymph node dissection and effects of neoadjuvant therapy are discussed...
  5. doi request reprint [Space-occupying lesion of the ribs]
    K J Schmitz
    Pathologisches Institut Recklinghausen, Mühlenstraße 31, 45659, Recklinghausen, Deutschland
    Pathologe 33:350-1. 2012
    ..Further immunohistochemical investigations detected an expression of the melanoma markers S-100 and melan-A. The diagnosis of a metastasis of an amelanotic malignant melanoma could therefore be verified...
  6. pmc Overexpression of cyclo-oxygenase-2 is an independent predictor of unfavourable outcome in node-negative breast cancer, but is not associated with protein kinase B (Akt) and mitogen-activated protein kinase (ERK1/2, p38) activation or with Her-2/neu signa
    K J Schmitz
    Institute of Pathology, University Hospital of Essen, Germany
    J Clin Pathol 59:685-91. 2006
    ....
  7. doi request reprint Cyclo-oxygenase-2 overexpression is a feature of early and well-differentiated hepatocellular carcinoma with a favourable prognosis
    K J Schmitz
    Institute of Pathology and Neuropathology, University Hospital Essen, University of Duisburg Essen, Hufelandstrasse 55, Essen 45122, Germany
    J Clin Pathol 62:690-3. 2009
    ..To determine the prognostic relevance of cyclo-oxygenase-2 (COX-2) expression in hepatocellular carcinoma (HCC) and its relationship to important clinicopathological parameters...
  8. ncbi request reprint Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations
    K J Schmitz
    Institute of Pathology and Neuropathology, University Hospital of Essen, Hufelandstr 55, 45122 Essen, Germany
    Virchows Arch 450:151-9. 2007
    ..We propose immunohistochemical determination of pERK1/2 status as a promising candidate for the identification of high-risk patients who would benefit from new anticancer drugs targeting the ERK pathway...
  9. doi request reprint "Preemptive" live donor liver transplantation for fibrolamellar hepatocellular carcinoma: a case report
    I Fouzas
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3806-7. 2008
    ..Herein we have reported successful "preemptive" living donor liver transplantation for presumed recurrence of FL-HCC after an extended right hepatectomy with resection and synthetic graft replacement of the inferior vena cava...
  10. pmc AKT and ERK1/2 signaling in intrahepatic cholangiocarcinoma
    K J Schmitz
    Institute of Pathology and Neuropathology, University Hospital of Essen, University Duisburg Essen, Germany
    World J Gastroenterol 13:6470-7. 2007
    ..Finally, we discuss future upcoming therapeutic options based on targeting these signaling pathways...
  11. pmc Differential expression of microRNA-675, microRNA-139-3p and microRNA-335 in benign and malignant adrenocortical tumours
    K J Schmitz
    Institute of Pathology and Neuropathology, University Hospital of Essen, University of Duisburg Essen, Essen, Germany
    J Clin Pathol 64:529-35. 2011
    ..The tremendous potential of microRNAs (miRNAs) as diagnostic biomarkers in surgical pathology has recently been shown in a broad variety of tumours...
  12. ncbi request reprint The high risk allele of a six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with favorable outcome in multiple cancers
    H S Bachmann
    University Hospital Essen, Essen, Germany
    J Clin Oncol 26:11073. 2008
    ..g. breast and colorectal cancer. The deletion variant of this polymorphism disrupts a Sp1 binding site and is associated with decreased mRNA expression in lymphocytes of healthy volunteers...
  13. doi request reprint [Characterization of the EGF receptor status in penile cancer : retrospective analysis of the course of the disease in 45 patients]
    C Börgermann
    Urologische Universitätsklinik, Essen, Deutschland
    Urologe A 48:1483-9. 2009
    ....
  14. ncbi request reprint Relationship and prognostic significance of phospho-(serine 166)-murine double minute 2 and Akt activation in node-negative breast cancer with regard to p53 expression
    K J Schmitz
    Institute of Pathology, Hufelandstr 55, 45122 Essen, Germany
    Virchows Arch 448:16-23. 2006
    ..However, due to the relatively small number of patients in this cohort, the results obtained need to be confirmed by larger cohorts...
  15. doi request reprint Wegener's granulomatosis in the thyroid mimicking a tumour
    K J Schmitz
    Institute of Pathology and Neuropathology, University Hospital of Essen, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Virchows Arch 452:571-4. 2008
    ..We conclude that, although extremely rare, Wegener's. granulomatosis should be added to the list of differential diagnoses of tumours of the thyroid gland...