Christian Schmidt

Summary

Country: Germany

Publications

  1. doi request reprint CR1 is potentially associated with rate of decline in sporadic Alzheimer's disease
    Christian Schmidt
    Department of Neurology, Clinical Dementia Center, Georg August University Medical Center, Robert Koch Str 40, 37075 Goettingen, Germany Electronic address
    J Clin Neurosci 21:1705-8. 2014
  2. pmc CSF prion protein concentration and cognition in patients with Alzheimer disease
    Christian Schmidt
    Clinical Dementia Center, Department of Neurology, Georg August University, Goettingen, Germany
    Prion 7:229-34. 2013
  3. doi request reprint Pre-progression rates in Alzheimer's disease revisited
    Christian Schmidt
    Clinical Dementia Center, Department of Neurology, Georg August University, Robert Koch Strasse 40, Goettingen, Germany
    J Alzheimers Dis 35:451-4. 2013
  4. pmc On the issue of transmissibility of Alzheimer disease: a critical review
    Christian Schmidt
    Clinical Dementia Center, Department of Neurology, Georg August University, Goettingen, Germany
    Prion 6:447-52. 2012
  5. doi request reprint Rapidly progressive Alzheimer's disease: a multicenter update
    Christian Schmidt
    National Reference Center for TSE Surveillance, Department of Neurology, Georg August University, Goettingen, Germany
    J Alzheimers Dis 30:751-6. 2012
  6. doi request reprint Alzheimer's disease: genetic polymorphisms and rate of decline
    Christian Schmidt
    Department of Neurology, Georg August University Hospital, Robert Koch Strasse 40, Goettingen, Germany
    Dement Geriatr Cogn Disord 33:84-9. 2012
  7. doi request reprint Comparative analysis of cerebrospinal fluid biomarkers in the differential diagnosis of neurodegenerative dementia
    Franc Llorens
    Clinical Dementia Center, Department of Neurology, University Medical Center Gottingen, Gottingen, Germany German Center for Neurodegenerative Diseases DZNE, Gottingen, Germany Electronic address
    Alzheimers Dement 12:577-89. 2016
  8. doi request reprint Clinical features of rapidly progressive Alzheimer's disease
    Christian Schmidt
    Department of Neurology, Hospital of the Georg August University Goettingen, Goettingen, Germany
    Dement Geriatr Cogn Disord 29:371-8. 2010
  9. doi request reprint Rapidly progressive Alzheimer disease
    Christian Schmidt
    Dementia Research Unit, Department of Neurology, Georg August Universitat Gottingen, Gottingen, Germany
    Arch Neurol 68:1124-30. 2011
  10. doi request reprint Increased albumin CSF/serum ratio in dementia with Lewy bodies
    Franc Llorens
    Clinical Dementia Center, Department of Neurology, University Medical Center Gottingen, Germany German Center for Neurodegenerative Diseases DZNE, Gottingen, Germany Electronic address
    J Neurol Sci 358:398-403. 2015

Detail Information

Publications17

  1. doi request reprint CR1 is potentially associated with rate of decline in sporadic Alzheimer's disease
    Christian Schmidt
    Department of Neurology, Clinical Dementia Center, Georg August University Medical Center, Robert Koch Str 40, 37075 Goettingen, Germany Electronic address
    J Clin Neurosci 21:1705-8. 2014
    ..Therefore, it may serve as a prognostic marker (among others) and may aid in differentiating slow from fast progressors early in the disease course...
  2. pmc CSF prion protein concentration and cognition in patients with Alzheimer disease
    Christian Schmidt
    Clinical Dementia Center, Department of Neurology, Georg August University, Goettingen, Germany
    Prion 7:229-34. 2013
    ..Therefore, we hypothesized that CSF levels of PrP (c) could be associated with cognitive function of AD patients at the time of diagnosis...
  3. doi request reprint Pre-progression rates in Alzheimer's disease revisited
    Christian Schmidt
    Clinical Dementia Center, Department of Neurology, Georg August University, Robert Koch Strasse 40, Goettingen, Germany
    J Alzheimers Dis 35:451-4. 2013
    ..Pre-progression rates (PPR) in Alzheimer's disease (AD) have been reported to be associated with cognitive and functional decline...
  4. pmc On the issue of transmissibility of Alzheimer disease: a critical review
    Christian Schmidt
    Clinical Dementia Center, Department of Neurology, Georg August University, Goettingen, Germany
    Prion 6:447-52. 2012
    ..In respect to this new experimental data, public health aspects as well as epidemiological data have to be reevaluated. In this article, the available experimental and epidemiological data are reviewed...
  5. doi request reprint Rapidly progressive Alzheimer's disease: a multicenter update
    Christian Schmidt
    National Reference Center for TSE Surveillance, Department of Neurology, Georg August University, Goettingen, Germany
    J Alzheimers Dis 30:751-6. 2012
    ..Thus, evidence of the existence of rpAD is accumulating. The APOE profile is intriguing, suggesting that this very rapid disease form might represent a distinct subtype of Alzheimer's disease...
  6. doi request reprint Alzheimer's disease: genetic polymorphisms and rate of decline
    Christian Schmidt
    Department of Neurology, Georg August University Hospital, Robert Koch Strasse 40, Goettingen, Germany
    Dement Geriatr Cogn Disord 33:84-9. 2012
    ..To investigate the influence of established genetic risk factors for Alzheimer's disease on the speed of disease progression...
  7. doi request reprint Comparative analysis of cerebrospinal fluid biomarkers in the differential diagnosis of neurodegenerative dementia
    Franc Llorens
    Clinical Dementia Center, Department of Neurology, University Medical Center Gottingen, Gottingen, Germany German Center for Neurodegenerative Diseases DZNE, Gottingen, Germany Electronic address
    Alzheimers Dement 12:577-89. 2016
    ..The analysis of cerebrospinal fluid biomarkers gains importance in clinical routine and is effective in substantiating dementia diagnosis in the differential diagnostic context...
  8. doi request reprint Clinical features of rapidly progressive Alzheimer's disease
    Christian Schmidt
    Department of Neurology, Hospital of the Georg August University Goettingen, Goettingen, Germany
    Dement Geriatr Cogn Disord 29:371-8. 2010
    ..To characterize clinical features, CSF biomarkers and genetic polymorphisms of patients suffering from a rapidly progressing subtype of Alzheimer's dementia (rpAD)...
  9. doi request reprint Rapidly progressive Alzheimer disease
    Christian Schmidt
    Dementia Research Unit, Department of Neurology, Georg August Universitat Gottingen, Gottingen, Germany
    Arch Neurol 68:1124-30. 2011
    ..Furthermore, we suggest that rapid, in this context, should be defined as a Mini-Mental State Examination score decrease of 6 points per year...
  10. doi request reprint Increased albumin CSF/serum ratio in dementia with Lewy bodies
    Franc Llorens
    Clinical Dementia Center, Department of Neurology, University Medical Center Gottingen, Germany German Center for Neurodegenerative Diseases DZNE, Gottingen, Germany Electronic address
    J Neurol Sci 358:398-403. 2015
    ....
  11. doi request reprint Baseline CSF/Serum-Ratio of Apolipoprotein E and Rate of Differential Decline in Alzheimer's Disease
    Christian Schmidt
    Clinical Dementia Center, Department of Neurology, Georg August University Medical Center, Goettingen, Germany
    J Alzheimers Dis 48:189-96. 2015
    ..In search of a biomarker potentially predictive of cognitive, functional, or motor decline, we analyzed the CSF to serum ratios of ApoE levels (CSF/serum ApoE) in AD patients in this regard...
  12. pmc Investigating the association of ApoE genotypes with blood-brain barrier dysfunction measured by cerebrospinal fluid-serum albumin ratio in a cohort of patients with different types of dementia
    Andre Karch
    Department of Neurology, Clinical Dementia Centre, University Hospital Gottingen, Gottingen, Germany Department of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    PLoS ONE 8:e84405. 2013
    ..In the present study we addressed the question if ApoE genotypes might be associated with BBB function measured by albumin ratio (QAlb) in a large cohort of patients with different types of dementia...
  13. doi request reprint Cerebrospinal fluid apolipoprotein E concentration and progression of Alzheimer's disease
    Christian Schmidt
    Clinical Dementia Center, Dept of Neurology, Georg August University Medical Center, Goettingen, Germany
    J Alzheimers Dis 43:1229-36. 2015
    ..In search of a potential biomarker, which would be predictive of cognitive, functional, or motor decline, we analyzed CSF apolipoprotein E (ApoE) levels of AD patients in this regard...
  14. doi request reprint Cytokine profiles and the role of cellular prion protein in patients with vascular dementia and vascular encephalopathy
    Matthias Schmitz
    Department of Neurology, University Medical Center Gottingen, and German Center for Neurodegenerative Diseases DZNE site Göttingen, Gottingen, Germany Electronic address
    Neurobiol Aging 36:2597-606. 2015
    ..Our data suggest that immunological modifiers play a role in VD and VE patients and provide evidence for an association of PrP(C) with immune and neurodegenerative markers. ..
  15. pmc CSF biomarkers and neuropsychological profiles in patients with cerebral small-vessel disease
    Peter Hermann
    Department of Neurology, Dementia Research Group, Georg August University Goettingen, Goettingen, Germany
    PLoS ONE 9:e105000. 2014
    ..Our results support the idea that a dysfunction of the blood-brain-barrier might be contributing factor in the development of cognitive decline in CSVD as it seems to be of more importance than the severity of white matter lesions. ..
  16. doi request reprint Cerebrospinal fluid apolipoprotein E concentration and severity of cognitive impairment in patients with newly diagnosed Alzheimer's disease
    Christian Schmidt
    1Department of Neurology, Clinical Dementia Center, Georg August University, Goettingen, Germany
    Am J Alzheimers Dis Other Demen 29:54-60. 2014
    ..Altered cerebrospinal fluid (CSF) and plasma levels have been previously reported in patients with AD. We hypothesized that CSF apoE levels of patients with newly diagnosed AD might be associated with their cognitive performance...
  17. doi request reprint Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases
    Franc Llorens
    Department of Neurology, Clinical Dementia Center, University Medical Center Gottingen, Gottingen, Germany German Center for Neurodegenerative Diseases DZNE, Site Göttingen, Germany Electronic address
    Alzheimers Dement . 2016
    ....