Bodo Cremers

Summary

Affiliation: Saarland University
Country: Germany

Publications

  1. ncbi [Preoperative cardiovascular risk evaluation--therapy]
    B Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 129:1260-4. 2004
  2. ncbi [Diuretics for hypertension and cardiac insufficiency]
    Bodo Cremers
    Universitatsklinikum des Saarlandes, Klinik fur Innere Medizin III, Homburg
    Pharm Unserer Zeit 35:322-32. 2006
  3. ncbi Perioperative hemodynamic measurements with an implantable monitoring system (Chronicle) in a patient with severe heart failure undergoing non-cardiac surgery
    B Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, 66421 Homburg, Germany
    Z Kardiol 93:908-12. 2004
  4. ncbi [Preoperative cardiovascular risk evaluation--diagnosis]
    B Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 129:1256-9. 2004
  5. ncbi [Preoperative cardiovascular risk evaluation--case report]
    B Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 129:1255. 2004
  6. ncbi Non erectile dysfunction application of sildenafil
    Bodo Cremers
    Medical Clinic and Polyclinic, Internal Medicine III, University Hospitals of the Saarland, Homburg, Germany
    Herz 28:325-33. 2003
  7. ncbi Catecholamine release in human heart by bupropion
    Bodo Cremers
    Medizinische Klinik und Poliklinik, Innere Medizin III, Universitatskliniken des Saarlandes, 66421 Homburg, Germany
    Eur J Pharmacol 467:169-71. 2003
  8. ncbi Modulation of myocardial contractility by lysophosphatidic acid (LPA)
    Bodo Cremers
    Medizinische Klinik und Poliklinik, Innere Medizin III, Universitatskliniken des Saarlandes, 66421, Homburg, Germany
    J Mol Cell Cardiol 35:71-80. 2003
  9. doi Effects of renal sympathetic denervation on exercise blood pressure, heart rate, and capacity in patients with resistant hypertension
    Sebastian Ewen
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Kirrberger Str, Geb 40, 66421 Homburg Saar, Germany
    Hypertension 63:839-45. 2014
  10. doi Long-term effects on vascular healing of bare metal stents delivered via paclitaxel-coated balloons in the porcine model of restenosis
    Bodo Cremers
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Catheter Cardiovasc Interv 80:603-10. 2012

Detail Information

Publications45

  1. ncbi [Preoperative cardiovascular risk evaluation--therapy]
    B Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 129:1260-4. 2004
  2. ncbi [Diuretics for hypertension and cardiac insufficiency]
    Bodo Cremers
    Universitatsklinikum des Saarlandes, Klinik fur Innere Medizin III, Homburg
    Pharm Unserer Zeit 35:322-32. 2006
  3. ncbi Perioperative hemodynamic measurements with an implantable monitoring system (Chronicle) in a patient with severe heart failure undergoing non-cardiac surgery
    B Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, 66421 Homburg, Germany
    Z Kardiol 93:908-12. 2004
    ..For the first time, we report a case of perioperative continuous hemodynamic monitoring with a long term-implanted device in a potential heart transplant patient...
  4. ncbi [Preoperative cardiovascular risk evaluation--diagnosis]
    B Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 129:1256-9. 2004
  5. ncbi [Preoperative cardiovascular risk evaluation--case report]
    B Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar
    Dtsch Med Wochenschr 129:1255. 2004
  6. ncbi Non erectile dysfunction application of sildenafil
    Bodo Cremers
    Medical Clinic and Polyclinic, Internal Medicine III, University Hospitals of the Saarland, Homburg, Germany
    Herz 28:325-33. 2003
    ..Moreover, in the treatment of Raynaud's phenomenon, a disease without highly effective medical treatment option yet, first observations with sildenafil seem to be promising...
  7. ncbi Catecholamine release in human heart by bupropion
    Bodo Cremers
    Medizinische Klinik und Poliklinik, Innere Medizin III, Universitatskliniken des Saarlandes, 66421 Homburg, Germany
    Eur J Pharmacol 467:169-71. 2003
    ..Our results suggest that bupropion exerts indirect sympathomimetic activity producing positive inotropic effects in human myocardium most probably by catecholamine release...
  8. ncbi Modulation of myocardial contractility by lysophosphatidic acid (LPA)
    Bodo Cremers
    Medizinische Klinik und Poliklinik, Innere Medizin III, Universitatskliniken des Saarlandes, 66421, Homburg, Germany
    J Mol Cell Cardiol 35:71-80. 2003
    ..This newly discovered action of LPA might be of pathophysiological importance in conditions like myocardial ischemia or inflammatory disorders when LPA release is enhanced...
  9. doi Effects of renal sympathetic denervation on exercise blood pressure, heart rate, and capacity in patients with resistant hypertension
    Sebastian Ewen
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Kirrberger Str, Geb 40, 66421 Homburg Saar, Germany
    Hypertension 63:839-45. 2014
    ..No changes were observed in the control group. In conclusion, renal denervation reduced blood pressure and heart rate during exercise, improved mean workload, and increased exercise time without impairing chronotropic competence. ..
  10. doi Long-term effects on vascular healing of bare metal stents delivered via paclitaxel-coated balloons in the porcine model of restenosis
    Bodo Cremers
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Catheter Cardiovasc Interv 80:603-10. 2012
    ..However, the long-term vascular effects of bare metal stents (BMS) delivered via PCB (PCB+BMS) are still unknown. The aim of this study was to assess the long-term effects of PCB+BMS on vascular healing and neointimal formation (NF)...
  11. doi Expanding the indication spectrum: renal denervation in diabetes
    Felix Mahfoud
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    EuroIntervention 9:R117-21. 2013
    ..This review highlights the background of approaching the renal sympathetic nerves as a potential new therapeutic option to improve glycaemic control in patients with resistant hypertension...
  12. ncbi Response and non-response to renal denervation: who is the ideal candidate?
    Christian Ukena
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    EuroIntervention 9:R54-7. 2013
    ..In order to ensure treatment success further criteria have to be fulfilled, such as exclusion of secondary hypertension and optimised medical therapy...
  13. ncbi Effects of sildenafil (viagra) on human myocardial contractility, in vitro arrhythmias, and tension of internal mammaria arteries and saphenous veins
    Bodo Cremers
    Medizinische Klinik und Poliklinik, Innere Medizin III, Chirurgische Klinik und Poliklinik, Abteilung Thorax und Herz, Homburg, Germany
    J Cardiovasc Pharmacol 41:734-43. 2003
    ..4 +/- 10.1%, n = 4, P < 0.02) as well as in veins (73.5 +/- 6.3%, n = 6, P < 0.02). Sildenafil exerts potent vasodilatory actions but has no direct influence on human myocardial contractility or proarrhythmic effects in vitro...
  14. doi Paclitaxel and sirolimus differentially affect growth and motility of endothelial progenitor cells and coronary artery smooth muscle cells
    Yvonne P Clever
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    EuroIntervention 7:K32-42. 2011
    ..This study investigates the time-dependent influence on growth and motility of paclitaxel and sirolimus alone and combined with the coating additive iopromide on EPC and hCASMC...
  15. doi Renal denervation in the treatment of hypertension
    Christian Ukena
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Kirrberger Strasse 1, Homburg Saar, Germany
    Curr Hypertens Rep 15:363-9. 2013
    ..By modulating sympathetic activity, RDN has the potential to provide benefit in a variety of diseases, but these concepts have to be evaluated in well-designed prospective controlled clinical trials. ..
  16. doi Effects of renal sympathetic denervation on heart rate and atrioventricular conduction in patients with resistant hypertension
    Christian Ukena
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Int J Cardiol 167:2846-51. 2013
    ..Renal sympathetic denervation (RDN) reduces sympathetic activity and blood pressure (BP) in patients with resistant hypertension. The present study aimed to investigate the effects of RDN on HR and other electrocardiographic parameters...
  17. doi Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension
    Felix Mahfoud
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Kirrberger Str, Geb 40, 66421 Homburg Saar, Germany
    Circulation 128:132-40. 2013
    ..Less is known about the effect of RDN on 24-hour BP measured by ambulatory BP monitoring and correlates of response in individuals with true or pseudoresistant hypertension...
  18. doi Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension
    Felix Mahfoud
    Klinik fur Innere Medizin III, Kardiologie, Angiologie, und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Kirrberger Str, Geb 40, 66421 Homburg Saar, Germany
    Hypertension 60:419-24. 2012
    ....
  19. ncbi Short- and long-term effects of a novel paclitaxel coated stent in the porcine coronary model
    Bruno Scheller
    Klinik für Innere Medizin III Kardiologie, Angiologie, Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Clin Res Cardiol 97:118-23. 2008
    ..The aim of the present animal studies was to evaluate the novel paclitaxel coated Coroflex. Please stent in the porcine coronary model...
  20. doi Long-term follow-up after treatment of coronary in-stent restenosis with a paclitaxel-coated balloon catheter
    Bruno Scheller
    Klinik fur Innere Medizin, III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    JACC Cardiovasc Interv 5:323-30. 2012
    ..This study presents long-term clinical follow-up, including binary restenosis rate and major adverse cardiovascular events, of the PACCOCATH-ISR (Treatment of In-Stent Restenosis by Paclitaxel Coated PTCA Balloons) I and II trial...
  21. doi Blood pressure reductions following catheter-based renal denervation are not related to improvements in adherence to antihypertensive drugs measured by urine/plasma toxicological analysis
    Sebastian Ewen
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Kirrberger Str, Geb 40, 66421, Homburg Saar, Germany
    Clin Res Cardiol 104:1097-105. 2015
    ..In conclusion, renal denervation can reduce office and ambulatory blood pressure in patients with resistant hypertension despite a significant reduction in adherence to antihypertensive treatment after 6 months. ..
  22. doi Reduced effect of percutaneous renal denervation on blood pressure in patients with isolated systolic hypertension
    Sebastian Ewen
    From the Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin S E, C U, D L, I K, B C, U L, M B, F M and Institut für Medizinische Biometrie, Epidemiologie und Medizinische Informatik S W, Universitatsklinikum des Saarlandes, Homburg Saar, Germany and Medizinische Klinik 4, Nephrologie und Hypertensiologie, Universitatsklinikum Erlangen, Erlangen, Germany R E S
    Hypertension 65:193-9. 2015
    ..In conclusion, renal denervation reduces office and ambulatory blood pressure in patients with ISH. However, this reduction is less pronounced compared with patients with CH. ..
  23. ncbi Drug coated balloons in acute coronary syndromes--opportunities and limitations
    Bruno Scheller
    Clinical and Experimental Interventional Cardiology, Internal Medicine III, University Hospital of Saarland, Homburg Saar, Germany
    Curr Vasc Pharmacol 10:472-5. 2012
    ..Patients in hemodynamic critical situations under catecholamine therapy may present with too small vessel diameters. Another clinically relevant scenario represents in-stent restenosis (ISR) which is frequently associated with ACS...
  24. doi CD14++CD16+ monocytes independently predict cardiovascular events: a cohort study of 951 patients referred for elective coronary angiography
    Kyrill S Rogacev
    Department of Internal Medicine IV, Saarland University Medical Center, Homburg Saar, Germany
    J Am Coll Cardiol 60:1512-20. 2012
    ..The aim of this study was to analyze the yet ill-defined relationship of distinct human monocyte subsets with cardiovascular outcomes in a broad patient population at cardiovascular risk...
  25. doi Impact of Lesion Placement on Efficacy and Safety of Catheter-Based Radiofrequency Renal Denervation
    Felix Mahfoud
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany Electronic address
    J Am Coll Cardiol 66:1766-75. 2015
    ..Insufficient procedural efficacy has been proposed to explain nonresponse to renal denervation (RDN)...
  26. doi Influence of a paclitaxel coated balloon in combination with a bare metal stent on restenosis and endothelial function: comparison with a drug eluting stent and a bare metal stent
    Yvonne P Clever
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Catheter Cardiovasc Interv 84:323-31. 2014
    ....
  27. doi Association of vitamin D status and blood pressure response after renal denervation
    Janine Pöss
    Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Kirrberger Strase, 66421, Homburg Saar, Germany
    Clin Res Cardiol 103:41-7. 2014
    ..Renal sympathetic denervation (RDN) reduces blood pressure in resistant hypertension. We hypothesized that vitamin D might influence blood pressure response to RDN...
  28. doi Treatment of a coronary bifurcation lesion with drug-coated balloons: lumen enlargement and plaque modification after 6 months
    Bruno Scheller
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Clin Res Cardiol 102:469-72. 2013
    ....
  29. ncbi Drug-eluting balloon: very short-term exposure and overlapping
    Bodo Cremers
    University of Saarland, Homburg Saar, Department of Internal Medicine III, Germany
    Thromb Haemost 101:201-6. 2009
    ..DEB were found to effectively reduce neointimal proliferation regardless of inflation time and dose within the tested range. No adverse reactions were seen as dose was increased to more than three times the clinically tested dose...
  30. ncbi Inhibition of neointimal proliferation after bare metal stent implantation with low-pressure drug delivery using a paclitaxel-coated balloon in porcine coronary arteries
    Bodo Cremers
    Department of Internal Medicine III, University of Saarland, 66421, Homburg Saar, Germany
    Clin Res Cardiol 101:385-91. 2012
    ....
  31. doi Blood pressure changes after catheter-based renal denervation are related to reductions in total peripheral resistance
    Sebastian Ewen
    aKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes bAbteilung Experimentelle und Klinische Pharmakologie, Universitat des Saarlandes, Homburg Saar, Germany cClinica Medica, Università Milano Bicocca dIstituto di Ricerca e Cura a Carattere Scientifico IRCCS Multimedica, Sesto San Giovanni, Milan, Italy
    J Hypertens 33:2519-25. 2015
    ..Renal denervation (RDN) can reduce sympathetic activity and blood pressure (BP) in patients with uncontrolled hypertension. The exact mechanisms by which RDN results in BP reductions are yet not fully established...
  32. doi Effects of catheter-based renal denervation on cardiac sympathetic activity and innervation in patients with resistant hypertension
    Luca Donazzan
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Kirrberger Str 1, Geb 40, 66421, Homburg Saar, Germany
    Clin Res Cardiol 105:364-71. 2016
    ..To investigate, whether renal denervation (RDN) has a direct effect on cardiac sympathetic activity and innervation density...
  33. doi Efficacy and safety of catheter-based radiofrequency renal denervation in stented renal arteries
    Felix Mahfoud
    From the Klinik für Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany F M, B C, D L, M B Medtronic Cardiovascular, Santa Rosa, CA S T, J R, D S J, R J M Klinik für Kardiologie and Angiologie II, Universitäts Herzzentrum Freiburg Bad Krozingen, Bad Krozingen, Germany T Z Brigham and Women s Hospital Heart and Vascular Center and Harvard Medical School, Boston, MA D L B and Prairie Heart Institute at St John s Hospital, Springfield, IL K R S
    Circ Cardiovasc Interv 7:813-20. 2014
    ..Although catheter-based renal denervation (RDN) can reduce blood pressure in certain patients with resistant hypertension, there are no data on the feasibility and safety of RDN in stented RA...
  34. doi Pulsatile venoarterial perfusion using a novel synchronized cardiac assist device augments coronary artery blood flow during ventricular fibrillation
    Bodo Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg, Germany
    Artif Organs 39:77-82. 2015
    ..Electrocardiographically triggered synchronized cardiac assist provides an additional increase of coronary artery flow. These promising results are to be confirmed in humans. ..
  35. doi Compassionate use of a paclitaxel coated balloon in patients with refractory recurrent coronary in-stent restenosis
    Yvonne P Clever
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Clin Res Cardiol 103:21-7. 2014
    ..This paper presents DCB therapy as compassionate use treatment before the balloons were available in Europe...
  36. doi Inhibition of neo-intimal hyperplasia in porcine coronary arteries utilizing a novel paclitaxel-coated scoring balloon catheter
    Bodo Cremers
    Department of Internal Medicine III, University of Saarland, Homburg Saar, Germany
    Catheter Cardiovasc Interv 84:1089-98. 2014
    ..A novel paclitaxel-coated scoring balloon was developed to overcome these limitations...
  37. doi The phosphatonin fibroblast growth factor 23 links calcium-phosphate metabolism with left-ventricular dysfunction and atrial fibrillation
    Sarah Seiler
    Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Hospital, Homburg Saar, Germany
    Eur Heart J 32:2688-96. 2011
    ..However, the association between FGF-23 and left-ventricular function is unknown, prompting us to investigate this relationship in our HOM SWEET HOMe study...
  38. doi Long-term follow-up of early versus delayed invasive approach after fibrinolysis in acute myocardial infarction
    Yvonne P Clever
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Circ Cardiovasc Interv 4:342-8. 2011
    ..The Southwest German Interventional Study in Acute Myocardial Infarction (SIAM III) evaluated the effects of transfer for early PCI in acute ST-elevation-myocardial infarction compared with a delayed PCI strategy...
  39. doi Comparison of two different paclitaxel-coated balloon catheters in the porcine coronary restenosis model
    Bodo Cremers
    Klinik fur Innere Medizin III, Kardiologie, Angiologie, Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Clin Res Cardiol 98:325-30. 2009
    ..Only scarce experimental and clinical data has been published on the new coating method. The aim of the present study was to compare the safety and efficacy of the two coatings in the porcine model...
  40. doi Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study
    Felix Mahfoud
    Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
    Circulation 123:1940-6. 2011
    ..We investigated the effect of catheter-based renal sympathetic denervation on glucose metabolism and blood pressure control in patients with resistant hypertension...
  41. ncbi [Preoperative risk evaluation in heart failure]
    B Cremers
    Klinik für Innere Medizin III Kardiologie, Angiologie und Internistische Intensivmedizin, Universitatsklinikum des Saarlandes, 66421, Homburg, Deutschland
    Internist (Berl) 48:921-8. 2007
    ....
  42. pmc Characterization of beta(1)-selectivity, adrenoceptor-G(s)-protein interaction and inverse agonism of nebivolol in human myocardium
    C Maack
    Innere Medizin III, Universität Homburg Saar, Germany
    Br J Pharmacol 132:1817-26. 2001
    ..Other mechanisms, i.e. the production of nitric oxide, may thus be responsible for its unique haemodynamic profile...
  43. ncbi Gene expression of adrenomedullin in failing myocardium: comparison to atrial natriuretic peptide
    Anselm T Bäumer
    Klinik III fur Innere Medizin, Universitat zu Koln, 50924 Köln, Germany
    J Appl Physiol (1985) 92:1058-63. 2002
    ..In dilated cardiomyopathy, the expression of AM was significantly increased in right and left ventricles compared with NF. In parallel, ventricular ANF expression was enhanced...
  44. ncbi Ongoing right ventricular hemodynamics in heart failure: clinical value of measurements derived from an implantable monitoring system
    Philip B Adamson
    Department of Internal Medicine Cardiology, University of Oklahoma Health Sciences Center, PO Box 26901, WP3120, Oklahoma City, OK 73190, USA
    J Am Coll Cardiol 41:565-71. 2003
    ..This study examined the characteristics of continuously measured right ventricular (RV) hemodynamic information derived from an implantable hemodynamic monitor (IHM) in heart failure patients...
  45. ncbi Continuous ambulatory right heart pressure measurements with an implantable hemodynamic monitor: a multicenter, 12-month follow-up study of patients with chronic heart failure
    Anthony Magalski
    Mid America Heart Institute, St Luke s Hospital, Kansas City, MO 64111, USA
    J Card Fail 8:63-70. 2002
    ..Pressure parameters derived from the implantable monitor were correlated to measurements made with a balloon-tipped catheter to establish accuracy and reproducibility over time in patients with chronic heart failure (CHF)...