Helmut Vedder

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. ncbi request reprint Immune-endocrine host response to endotoxin in major depression
    Helmut Vedder
    Max Planck Institute of Psychiatry, Munich, Germany
    J Psychiatr Res 41:280-9. 2007
  2. pmc Meta-analysis on the effect of the N363S polymorphism of the glucocorticoid receptor gene (GRL) on human obesity
    Amelia Marti
    Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
    BMC Med Genet 7:50. 2006
  3. doi request reprint Relationships among endocrine and signaling-related responses to antidepressants in human monocytic U-937 blood cells: analysis of factors and response patterns
    Stefan Gebhardt
    Department of Psychiatry and Psychotherapy, Philipps University of Marburg, Rudolf Bultmann Strasse 8, D 35033 Marburg, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 32:1682-7. 2008
  4. ncbi request reprint Serotonergic effects of clozapine and its metabolites in hippocampal HT22 cells
    Philip Heiser
    Department of Child and Adolescent Psychiatry and Psychotherapy, Hans Sachs Str 6, Philipps University of Marburg, Marburg, Germany
    Psychiatry Res 112:221-9. 2002
  5. ncbi request reprint Differential effects of antidepressants on glucocorticoid receptors in human primary blood cells and human monocytic U-937 cells
    Andreas Heiske
    Department of Psychiatry and Psychotherapy, Philipps University, Marburg, Germany
    Neuropsychopharmacology 28:807-17. 2003
  6. ncbi request reprint Pharmacokinetics of clozapine and its metabolites in hippocampal HT22 cells
    Philip Heiser
    Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University of Marburg, Hans Sachs Str 6, 35037 Marburg, Germany
    Eur J Pharmacol 476:167-72. 2003
  7. ncbi request reprint Effects of haloperidol, clozapine and olanzapine on the survival of human neuronal and immune cells in vitro
    Philip Heiser
    Department of Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany
    J Psychopharmacol 21:851-6. 2007
  8. ncbi request reprint Effects of clozapine and its metabolites on the 5-HT2 receptor system in cortical and hippocampal cells in vitro
    Philip Heiser
    Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University, Hans Sachs Str 6, Marburg 35037, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 28:297-302. 2004
  9. doi request reprint Effects of antidepressants on mRNA levels of antioxidant enzymes in human monocytic U-937 cells
    Andreas Johannes Schmidt
    Department of Psychiatry and Psychotherapy, Philipps University of Marburg, Rudolf Bultmann Str 8, 35033 Marburg, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 32:1567-73. 2008
  10. ncbi request reprint Effects of oxidative challenge and calcium on ATP-levels in neuronal cells
    Michael Teepker
    Department of Psychiatry and Psychotherapy, Philipps University, Marburg, Germany
    Neurotoxicology 28:19-26. 2007

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Immune-endocrine host response to endotoxin in major depression
    Helmut Vedder
    Max Planck Institute of Psychiatry, Munich, Germany
    J Psychiatr Res 41:280-9. 2007
    ..An impaired hypothalamic-pituitary-adrenocortical (HPA) function is a well-established finding in major depression (MD), but it is still unclear how this dysfunction affects immune responses in this disorder...
  2. pmc Meta-analysis on the effect of the N363S polymorphism of the glucocorticoid receptor gene (GRL) on human obesity
    Amelia Marti
    Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
    BMC Med Genet 7:50. 2006
    ..Individual studies may lack statistical power which may result in disparate results. This limitation can be overcome using meta-analytic techniques...
  3. doi request reprint Relationships among endocrine and signaling-related responses to antidepressants in human monocytic U-937 blood cells: analysis of factors and response patterns
    Stefan Gebhardt
    Department of Psychiatry and Psychotherapy, Philipps University of Marburg, Rudolf Bultmann Strasse 8, D 35033 Marburg, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 32:1682-7. 2008
    ....
  4. ncbi request reprint Serotonergic effects of clozapine and its metabolites in hippocampal HT22 cells
    Philip Heiser
    Department of Child and Adolescent Psychiatry and Psychotherapy, Hans Sachs Str 6, Philipps University of Marburg, Marburg, Germany
    Psychiatry Res 112:221-9. 2002
    ....
  5. ncbi request reprint Differential effects of antidepressants on glucocorticoid receptors in human primary blood cells and human monocytic U-937 cells
    Andreas Heiske
    Department of Psychiatry and Psychotherapy, Philipps University, Marburg, Germany
    Neuropsychopharmacology 28:807-17. 2003
    ..Taken together, our data further support the assumption that ADs influence the neuroendocrine and immune system via effects on cellular GRs...
  6. ncbi request reprint Pharmacokinetics of clozapine and its metabolites in hippocampal HT22 cells
    Philip Heiser
    Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University of Marburg, Hans Sachs Str 6, 35037 Marburg, Germany
    Eur J Pharmacol 476:167-72. 2003
    ..Moreover, CYP1A2 mRNA levels were significantly changed by incubation with clozapine 200...
  7. ncbi request reprint Effects of haloperidol, clozapine and olanzapine on the survival of human neuronal and immune cells in vitro
    Philip Heiser
    Department of Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany
    J Psychopharmacol 21:851-6. 2007
    ..These findings suggest that antipsychotic substances of different classes exert differential metabolic effects in both neuronal and immune cell systems...
  8. ncbi request reprint Effects of clozapine and its metabolites on the 5-HT2 receptor system in cortical and hippocampal cells in vitro
    Philip Heiser
    Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University, Hans Sachs Str 6, Marburg 35037, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 28:297-302. 2004
    ....
  9. doi request reprint Effects of antidepressants on mRNA levels of antioxidant enzymes in human monocytic U-937 cells
    Andreas Johannes Schmidt
    Department of Psychiatry and Psychotherapy, Philipps University of Marburg, Rudolf Bultmann Str 8, 35033 Marburg, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 32:1567-73. 2008
    ..Based on the large number of significant effects of all types of antidepressants tested on various antioxidant enzymes, we suggest that antioxidant enzymes may represent important targets in the course of antidepressive treatment...
  10. ncbi request reprint Effects of oxidative challenge and calcium on ATP-levels in neuronal cells
    Michael Teepker
    Department of Psychiatry and Psychotherapy, Philipps University, Marburg, Germany
    Neurotoxicology 28:19-26. 2007
    ..Since disturbed ATP- and calcium (Ca2+)-metabolism may be involved in this process, we here evaluated the effects of H2O2-induced oxidative stress and the involvement of Ca2+-regulation on neuronal energy metabolism...
  11. ncbi request reprint Interleukin-6 induces glutathione in hippocampal cells
    Andreas Johannes Schmidt
    Department of Psychiatry and Psychotherapy, Philipps University of Marburg, Rudolf Bultmann Str 8, 35033 Marburg, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 29:321-6. 2005
    ..Further studies with an IL-6 antibody strongly support the specificity of the effects. These results suggest that IL-6 plays a substantial role in the regulation of GSH in hippocampal cells...
  12. ncbi request reprint 2-OH-estradiol, an endogenous hormone with neuroprotective functions
    Michael Teepker
    Department of Psychiatry and Psychotherapy, Philipps University, Rudolf Bultmann Str 8, D 35033, Marburg, Germany
    J Psychiatr Res 37:517-23. 2003
    ....
  13. ncbi request reprint Sex differences in cortisol response to noxious stress
    Christiane Zimmer
    Department of Clinical Psychology, University of Freiburg, Freiburg, Germany
    Clin J Pain 19:233-9. 2003
    ..Data concerning sex differences in cortisol response patterns have revealed inconsistent results so far. The purpose of the present study was to examine sex differences in subjective pain and cortisol response to a noxious stressor...
  14. ncbi request reprint Borna disease virus-induced accumulation of macrophage migration inhibitory factor in rat brain astrocytes is associated with inhibition of macrophage infiltration
    Michael Bacher
    Institute of Immunology, Philipps University, Marburg, Germany
    Glia 37:291-306. 2002
    ....