R Arnold

Summary

Affiliation: Philipps University
Country: Germany

Publications

  1. ncbi request reprint Endocrine tumours of the gastrointestinal tract. Introduction: definition, historical aspects, classification, staging, prognosis and therapeutic options
    R Arnold
    Department of Internal Medicine, Division of Gastroenterology and Endocrinology, Philipps University, Marburg, Germany
    Best Pract Res Clin Gastroenterol 19:491-505. 2005
  2. doi request reprint [Gastroenterology in Germany: results of a survey in hospitals and practices]
    R Arnold
    Die Institutsangaben sind am Ende des Beitrags gelistet
    Z Gastroenterol 47:563-74. 2009
  3. ncbi request reprint Treatment of neuroendocrine GEP tumours with somatostatin analogues: a review
    R Arnold
    Department of Internal Medicine, Philipps University, Marburg, Germany
    Digestion 62:84-91. 2000
  4. ncbi request reprint Diagnosis and differential diagnosis of hypergastrinemia
    Rudolf Arnold
    Klinik fur Innere Medizin, Schwerpunkt Gastroenterologie und Endokrinologie, Klinikum Giessen Marburg, Standort Marburg, Philipps Universitat, Marburg, Germany
    Wien Klin Wochenschr 119:564-9. 2007
  5. ncbi request reprint Octreotide versus octreotide plus interferon-alpha in endocrine gastroenteropancreatic tumors: a randomized trial
    Rudolf Arnold
    Division of Gastroenterology and Endocrinology, Department of Internal Medicine, Philipps University, Marburg, Germany
    Clin Gastroenterol Hepatol 3:761-71. 2005
  6. ncbi request reprint Endocrine tumours of the gastrointestinal tract: Chemotherapy
    R Arnold
    Department of Internal Medicine, Division of Gastroenterology and Endocrinology, Philipps University, Baldingerstr, Germany
    Best Pract Res Clin Gastroenterol 19:649-56. 2005
  7. pmc Exendin(9-39)amide is an antagonist of glucagon-like peptide-1(7-36)amide in humans
    J Schirra
    Clinical Research Unit for Gastrointestinal Endocrinology and Department of Gastroenterology and Endocrinology, Philipps University, 35033 Marburg, Germany
    J Clin Invest 101:1421-30. 1998
  8. ncbi request reprint Transient transcriptional activation of gastrin during sodium butyrate-induced differentiation of islet cells
    B Simon
    Department of Internal Medicine, Philipps University, Marburg, Germany
    Regul Pept 70:143-8. 1997
  9. ncbi request reprint The effects of two FMRFamide related peptides (A-18-F-amide and F-8-F-amide; 'morphine modulating peptides') on the endocrine and exocrine rat pancreas
    H C Fehmann
    Department of Internal Medicine, Philipps University, Marburg, Federal Republic of Germany
    Neuropeptides 17:87-92. 1990
  10. ncbi request reprint Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance
    M M Byrne
    Department of Internal Medicine, Philipps University, Marburg, Germany
    Diabetes 47:1259-65. 1998

Detail Information

Publications57

  1. ncbi request reprint Endocrine tumours of the gastrointestinal tract. Introduction: definition, historical aspects, classification, staging, prognosis and therapeutic options
    R Arnold
    Department of Internal Medicine, Division of Gastroenterology and Endocrinology, Philipps University, Marburg, Germany
    Best Pract Res Clin Gastroenterol 19:491-505. 2005
    ..Patients with endocrine tumours have an increased risk of developing synchronous and metachronous non-endocrine malignancies. Most current treatment options are not supported by prospective, randomised and controlled trials...
  2. doi request reprint [Gastroenterology in Germany: results of a survey in hospitals and practices]
    R Arnold
    Die Institutsangaben sind am Ende des Beitrags gelistet
    Z Gastroenterol 47:563-74. 2009
    ..The results of this survey offer a valid basis for continuing discussions as to how gastroenterology should develop in Germany...
  3. ncbi request reprint Treatment of neuroendocrine GEP tumours with somatostatin analogues: a review
    R Arnold
    Department of Internal Medicine, Philipps University, Marburg, Germany
    Digestion 62:84-91. 2000
    ..Somatostatin and its long-acting analogues are effective in symptom control in patients with functionally active neuroendocrine GEP tumours. Several in vitro and in vivo reports suggest that they are also able to control tumour growth...
  4. ncbi request reprint Diagnosis and differential diagnosis of hypergastrinemia
    Rudolf Arnold
    Klinik fur Innere Medizin, Schwerpunkt Gastroenterologie und Endokrinologie, Klinikum Giessen Marburg, Standort Marburg, Philipps Universitat, Marburg, Germany
    Wien Klin Wochenschr 119:564-9. 2007
    ..Other conditions with moderate hypergastrinemia as treatment with proton pump inhibitors, gastric outlet obstruction, previous vagotomy, chronic renal failure or short bowel syndrome are of minor clinical importance...
  5. ncbi request reprint Octreotide versus octreotide plus interferon-alpha in endocrine gastroenteropancreatic tumors: a randomized trial
    Rudolf Arnold
    Division of Gastroenterology and Endocrinology, Department of Internal Medicine, Philipps University, Marburg, Germany
    Clin Gastroenterol Hepatol 3:761-71. 2005
    ....
  6. ncbi request reprint Endocrine tumours of the gastrointestinal tract: Chemotherapy
    R Arnold
    Department of Internal Medicine, Division of Gastroenterology and Endocrinology, Philipps University, Baldingerstr, Germany
    Best Pract Res Clin Gastroenterol 19:649-56. 2005
    ..Chemotherapy is, however, almost ineffective in patients with well-differentiated neuroendocrine tumours originating in the gastrointestinal tract ('carcinoids')...
  7. pmc Exendin(9-39)amide is an antagonist of glucagon-like peptide-1(7-36)amide in humans
    J Schirra
    Clinical Research Unit for Gastrointestinal Endocrinology and Department of Gastroenterology and Endocrinology, Philipps University, 35033 Marburg, Germany
    J Clin Invest 101:1421-30. 1998
    ..The pancreatic A cell is under a tonic inhibitory control of GLP-1. At hyperglycemia, the B cell is under a tonic stimulatory control of GLP-1...
  8. ncbi request reprint Transient transcriptional activation of gastrin during sodium butyrate-induced differentiation of islet cells
    B Simon
    Department of Internal Medicine, Philipps University, Marburg, Germany
    Regul Pept 70:143-8. 1997
    ....
  9. ncbi request reprint The effects of two FMRFamide related peptides (A-18-F-amide and F-8-F-amide; 'morphine modulating peptides') on the endocrine and exocrine rat pancreas
    H C Fehmann
    Department of Internal Medicine, Philipps University, Marburg, Federal Republic of Germany
    Neuropeptides 17:87-92. 1990
    ..05; second phase: 29%, p less than 0.05). Both peptides were without effect on basal and CCK-8-stimulated amylase release from isolated incubated rat pancreatic acini...
  10. ncbi request reprint Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance
    M M Byrne
    Department of Internal Medicine, Philipps University, Marburg, Germany
    Diabetes 47:1259-65. 1998
    ..Beta-cell dysfunction was improved by GLP-1 infusion, suggesting that early GLP-1 therapy may preserve beta-cell function in subjects with IGT or mild NIDDM...
  11. ncbi request reprint GLP-1-induced alterations in the glucose-stimulated insulin secretory dose-response curve
    A Brandt
    The Clinical Research Unit for Gastrointestinal Endocrinology, Department of Internal Medicine, Philipps University, 35033 Marburg, Germany
    Am J Physiol Endocrinol Metab 281:E242-7. 2001
    ....
  12. ncbi request reprint Somatostatin analogues in the treatment of endocrine tumors of the gastrointestinal tract
    R Arnold
    Department of Internal Medicine, Division of Gastroenterology and Endocrinology, Philips University, Marburg, Germany
    Expert Opin Pharmacother 3:643-56. 2002
    ....
  13. ncbi request reprint Gastric argyrophil (enterochromaffin-like), gastrin, and somatostatin cells after proximal selective vagotomy in man
    H Koop
    Department of Medicine, Philipps University, Marburg, Germany
    Dig Dis Sci 38:295-302. 1993
    ..It is concluded that: (1) a major role of the vagal nerve as a trophic factor for enterochromaffin-like cells could not be demonstrated after PSV, and (2) moderate hypergastrinemia after PSV did not induce proliferation of ECL cells...
  14. ncbi request reprint Neuropeptide Y in the paraventricular nucleus of the hypothalamus stimulates colonic transit by peripheral cholinergic and central CRF pathways
    H Monnikes
    Department of Internal Medicine, Philipps University of Marburg, Marburg, Germany
    Neurogastroenterol Motil 12:343-52. 2000
    ..The effect of NPY in the PVN on colonic motor function depends on central CRF and peripheral cholinergic pathways...
  15. pmc Effects of glucagon-like peptide-1(7-36)amide on antro-pyloro-duodenal motility in the interdigestive state and with duodenal lipid perfusion in humans
    J Schirra
    Clinical Research Unit for Gastrointestinal Endocrinology and Department of Gastroenterology and Endocrinology, Philipps University, Marburg, Germany
    Gut 46:622-31. 2000
    ..Glucagon-like peptide-1(7-36)amide (GLP-1) is a gut hormone released postprandially. Synthetic GLP-1 strongly inhibits gastric emptying in healthy subjects and in patients with diabetes mellitus...
  16. ncbi request reprint RAP1-like binding activity in islet cells corresponds to members of the Sp1 family of transcription factors
    B Simon
    Department of Internal Medicine, Philipps University, Marburg, Germany
    FEBS Lett 411:383-8. 1997
    ..These data reveal that the zinc finger proteins Sp1 and Sp3 do have similar binding specificities as the multifunctional yeast RAP1 protein...
  17. ncbi request reprint mRNA expression patterns of insulin-like growth factor system components in human neuroendocrine tumours
    U Wulbrand
    Department of Internal Medicine, Philipps University Marburg, Germany
    Eur J Clin Invest 30:729-39. 2000
    ....
  18. ncbi request reprint Frequent abnormalities of the putative tumor suppressor gene FHIT at 3p14.2 in pancreatic carcinoma cell lines
    B Simon
    Department of Internal Medicine, Philipps University, Marburg, Germany
    Cancer Res 58:1583-7. 1998
    ..Fhit protein expression was dependent on a full-length FHIT transcript. The results suggest that the FHIT gene may be a target tumor suppressor gene involved in pancreatic carcinogenesis...
  19. ncbi request reprint Inhibitory effects of hyperglycaemia on fed jejunal motility: potential role of hyperinsulinaemia
    M M Byrne
    Department of Gastroenterology and Endocrinology, University of Marburg, Germany
    Eur J Clin Invest 28:72-8. 1998
    ..This study was undertaken to establish the effects of hyperglycaemia on fed jejunal motility and small intestinal transit time, and to establish if the effects of hyperglycaemia are mediated in part by hyperinsulinaemia...
  20. ncbi request reprint Ghrelin-induced stimulation of colonic propulsion is dependent on hypothalamic neuropeptide Y1- and corticotrophin-releasing factor 1 receptor activation
    J J Tebbe
    Department of Internal Medicine, Division of Gastroenterology and Endocrinology, Philipps Universitat Marburg, Marburg, Germany
    J Neuroendocrinol 17:570-6. 2005
    ..These results suggest that ghrelin can act as central modulator of gastrointestinal motor functions at the level of the PVN via neuropeptide Y1- and CRF1 receptor-dependent mechanisms...
  21. ncbi request reprint Cocaine- and amphetamine-regulated transcript stimulates colonic motility via central CRF receptor activation and peripheral cholinergic pathways in fed, conscious rats
    J J Tebbe
    Division of Gastroenterology and Endocrinology, Department of Internal Medicine, Philipps Universitat Marburg, Baldinger Strasse 1, 35033 Marburg, Germany
    Neurogastroenterol Motil 16:489-96. 2004
    ..The results suggest that CART acts in the central nervous system to modulate behavioural motor function via a central CRF receptor-dependent mechanism and peripheral cholinergic pathways...
  22. ncbi request reprint [Barrett esophagus: epidemiology, incidence of carcinoma, need for screening]
    R Arnold
    Klinikum der Philipps Universität, Klinik fur Innere Medizin, Gastroenterologie, Stoffwechsel und Endokrinologie, Baldingerstrasse, 35043 Marburg
    Internist (Berl) 44:43-4, 47-51. 2003
  23. ncbi request reprint Growth factor receptor expression in human gastroenteropancreatic neuroendocrine tumours
    U Wulbrand
    Philipps University Marburg, Germany
    Eur J Clin Invest 28:1038-49. 1998
    ..Human gastroenteropancreatic neuroendocrine tumours are functionally and biologically heterogeneous, but their exact growth factor receptor expression pattern, important for onco- and carcinogenesis, remains unknown...
  24. pmc Effects of glucagon-like peptide-1(7-36)amide on motility and sensation of the proximal stomach in humans
    J Schirra
    Department of Gastroenterology and Endocrinology, Philipps University, Marburg, Germany
    Gut 50:341-8. 2002
    ..Glucagon-like peptide-1(7-36)amide (GLP-1) retards gastric emptying, reduces food intake, and inhibits antroduodenal and stimulates pyloric motility...
  25. ncbi request reprint Placebo-controlled, double-blind, prospective, randomized study of the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors: A report from the PROMID study group
    R Arnold
    Philipps University, Marburg, Germany
    J Clin Oncol 27:4508. 2009
    ..The analysis of the first randomized, double-blind, placebo-controlled, multicenter, phase IIIb study of octreotide LAR in patients with metastatic NETs of the midgut is presented...
  26. ncbi request reprint Proliferation of endocrine cells in the rat stomach caused by drug-induced achlorhydria
    R Eissele
    Department of Internal Medicine, Philipps University, Marburg, Germany
    Gastroenterology 101:70-6. 1991
    ....
  27. ncbi request reprint [Helicobacter pylori eradication: always?--contra]
    R Arnold
    Klinik für Innere Medizin Schwerpunkt Gastroenterologie und Endokrinologie, Philipps Universitat, Marburg
    Dtsch Med Wochenschr 129:43-4. 2004
  28. ncbi request reprint Tamoxifen or cyproterone acetate in combination with buserelin are ineffective in patients with pancreatic adenocarcinoma
    B Swarovsky
    Abteilung für Gastroenterologie und Stoffwechsel, Philipps Universitat, Marburg, BRD
    Oncology 50:226-9. 1993
    ..In conclusion, complete androgen blockade and antiestrogens in combination with LH-RH agonist cannot be recommended in patients with widespread pancreatic adenocarcinoma...
  29. ncbi request reprint Transarterial chemoembolization of advanced liver metastases of neuroendocrine tumors--a retrospective single-center analysis
    O Kress
    Department of Diagnostic Radiology, Philipps University Hospital, Marburg, Germany
    Digestion 68:94-101. 2003
    ..Transcatheter arterial chemoembolization (TACE) is thought to be an effective symptomatic and antiproliferative treatment in patients with otherwise progressive disease...
  30. ncbi request reprint Intestinal proliferation and delayed intestinal transit in a patient with a GLP-1-, GLP-2- and PYY-producing neuroendocrine carcinoma
    M M Byrne
    Department of Gastroenterology and Endocrinology, Philipps University, Baldingerstrasse, D 35033 Marburg, Germany
    Digestion 63:61-8. 2001
    ..This is the first case report demonstrating the overproduction of GLP-1, GLP-2 and PYY from an neuroendocrine tumor, in a patient with intestinal hypertrophy and delayed intestinal transit time...
  31. ncbi request reprint The efficacy of a 40-mg extended-release formulation of cisapride in the treatment of patients with gastro-oesophageal reflux
    M Katschinski
    Department of Gastroenterology, Philipps University, Marburg, Germany
    Aliment Pharmacol Ther 14:113-22. 2000
    ..This study was conducted to assess the efficacy of a novel 40-mg extended-release formulation of cisapride in reducing gastro-oesophageal reflux...
  32. ncbi request reprint Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling
    A Trumper
    Department of Internal Medicine, Division of Gastroenterology and Metabolism, Philipps University, Marburg, Germany D 35033
    Mol Endocrinol 15:1559-70. 2001
    ....
  33. ncbi request reprint Peripheral administration of cholecystokinin activates c-fos expression in the locus coeruleus/subcoeruleus nucleus, dorsal vagal complex and paraventricular nucleus via capsaicin-sensitive vagal afferents and CCK-A receptors in the rat
    H Monnikes
    Department of Internal Medicine, Philipps University of Marburg, Germany
    Brain Res 770:277-88. 1997
    ..These findings suggest that the LC/SC is involved in CNS-mediated regulatory influences of peripheral CCK...
  34. ncbi request reprint Involvement of CCK in the paraventricular nucleus of the hypothalamus in the CNS regulation of colonic motility
    H Monnikes
    Department of Internal Medicine, Philipps University of Marburg, Germany
    Digestion 62:178-84. 2000
    ..The data suggest, that endogenous CCK in the paraventricular nucleus of the hypothalamus unfolds a stimulatory effect on colonic transit through action on CCK-B receptors...
  35. ncbi request reprint Prognostic value of heart rate variability analysis in patients with carcinoid syndrome
    J Hoffmann
    Cardiovascular Section, Department of Internal Medicine, Philipps University of Marburg, Baldingerstrasse, D 35033 Marburg, Germany
    Digestion 63:35-42. 2001
    ..The prognostic relevance of this finding, however, was not clear...
  36. pmc Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies
    H Kulaksiz
    Department of Internal Medicine, Division of Gastroenterology, Ruprecht Karls University, Heidelberg, Germany
    Gut 50:52-60. 2002
    ....
  37. ncbi request reprint Expression and cell-specific localization of the cholecystokinin B/gastrin receptor in the human stomach
    H Kulaksiz
    Department of Internal Medicine, Philipps University, Marburg, Germany
    Cell Tissue Res 299:289-98. 2000
    ....
  38. ncbi request reprint Added value of gastrin receptor scintigraphy in comparison to somatostatin receptor scintigraphy in patients with carcinoids and other neuroendocrine tumours
    Martin Gotthardt
    Department of Nuclear Medicine, Radboud University Nijmegen Medical Center, Postbus 9101, 6500 HB Nijmegen, The Netherlands
    Endocr Relat Cancer 13:1203-11. 2006
    ..GRS should be performed in selected patients as it may provide additional information in patients with NET with equivocal or absent somatostatin uptake...
  39. ncbi request reprint Nuclear survivin is a powerful novel prognostic marker in gastroenteropancreatic neuroendocrine tumor disease
    Patricia Grabowski
    Medical Clinic I, Gastroenterology Infectious Diseases Rheumatology, Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Neuroendocrinology 81:1-9. 2005
    ..We propose that the determination of nuclear survivin expression could be used to individualize therapeutic strategies in this tumor entity in the future...
  40. ncbi request reprint Rapid and sustained relief from the symptoms of carcinoid syndrome: results from an open 6-month study of the 28-day prolonged-release formulation of lanreotide
    Philippe Ruszniewski
    Hopital Beaujon, Clichy, France
    Neuroendocrinology 80:244-51. 2004
    ..Treatment was well tolerated. 28-day PR lanreotide was effective in reducing the symptoms and biochemical markers associated with carcinoid syndrome...
  41. ncbi request reprint Analysis of molecular pathways in sporadic neuroendocrine tumors of the gastro-entero-pancreatic system
    Christian N Arnold
    Department of Internal Medicine, University of Freiburg, Hugstetterstrasse 55, D 79106 Freiburg, Germany
    Int J Cancer 120:2157-64. 2007
    ..The analyses identified significant genetic and epigenetic alterations in well-differentiated fore- and mid-gut NET. CIMP, similar to Ki-67, might turn out to be of prognostic relevance...
  42. ncbi request reprint Programmed cell death protein 4 (PDCD4) acts as a tumor suppressor in neuroendocrine tumor cells
    Rüdiger Göke
    Clinical Research Unit for Gastrointestinal Endocrinology, University of Marburg, Marburg, Germany
    Ann N Y Acad Sci 1014:220-1. 2004
    ..This is most likely caused by a PDCD4-induced downregulation of carbonic anhydrase type II which catalyzes the production of bicarbonate, a fundamental substrate for many cellular pathways...
  43. ncbi request reprint Radioiodide treatment after sodium iodide symporter gene transfer is a highly effective therapy in neuroendocrine tumor cells
    Meike L Schipper
    Departments of Nuclear Medicine, Philipps University Marburg, 35043 Marburg, Germany
    Cancer Res 63:1333-8. 2003
    ..In conclusion, radioiodide treatment after NIS gene transfer appears to be a promising novel approach in the therapy of neuroendocrine tumors if its highly encouraging in vitro effectiveness can be transferred to the in vivo situation...
  44. ncbi request reprint Consensus guidelines for the management of patients with digestive neuroendocrine tumors--well-differentiated jejunal-ileal tumor/carcinoma
    Barbro Eriksson
    Department of Medical Sciences, Endocrine Oncology Unit, University Hospital, Uppsala, Sweden
    Neuroendocrinology 87:8-19. 2008
  45. doi request reprint Plasma chromogranin A as marker for survival in patients with metastatic endocrine gastroenteropancreatic tumors
    Rudolf Arnold
    Department of Internal Medicine, Division of Gastroenterology and Endocrinology, Philipps University, Marburg, Germany
    Clin Gastroenterol Hepatol 6:820-7. 2008
    ....
  46. pmc Molecular characteristics and predictors of survival in patients with malignant neuroendocrine tumors
    Christian N Arnold
    Department of Internal Medicine II, University of Freiburg, D 79106 Freiburg, Germany
    Int J Cancer 123:1556-64. 2008
    ..Predictors of a poor outcome in patients with NET are poor differentiation, a high Ki-67 index and p16 methylation...
  47. ncbi request reprint Well-differentiated duodenal tumor/carcinoma (excluding gastrinomas)
    Robert T Jensen
    Digestive Diseases Branch, NIDDK, NIH, Bethesda, MD, USA
    Neuroendocrinology 84:165-72. 2006
  48. doi request reprint Somatostatin-producing neuroendocrine tumors of the duodenum and pancreas: incidence, types, biological behavior, association with inherited syndromes, and functional activity
    Nele Garbrecht
    Department of Pathology, University of Kiel, Michaelisstr 11, Kiel, Germany
    Endocr Relat Cancer 15:229-41. 2008
    ..MEN1-associated SOM-NETs and GCPGs follow a benign course, while somatostatin-producing pdNECs are aggressive neoplasms. The occurrence of the so-called somatostatinoma syndrome appears to be extremely uncommon...
  49. ncbi request reprint Well-differentiated gastric tumors/carcinomas
    Philippe Ruszniewski
    Department of Gastroenterology, Beaujon Hospital, Clichy, France
    Neuroendocrinology 84:158-64. 2006
  50. ncbi request reprint BRAF gene mutations are rare events in gastroenteropancreatic neuroendocrine tumors
    Andrea Tannapfel
    Institute of Pathology, University of Leipzig, Germany
    Am J Clin Pathol 123:256-60. 2005
    ..Nevertheless, activation of the RAF/mitogen-activated protein kinase pathway might have a causative role in the development of neuroendocrine tumors, independent of BRAF or k-ras-2 mutation...
  51. ncbi request reprint Effects of the tyrosine kinase inhibitor imatinib on neuroendocrine tumor cell growth
    Brigitte Lankat-Buttgereit
    Clinical Research Unit for Gastrointestinal Endocrinology, Department of Gastroenterology, Endocrinology and Metabolism, University of Marburg, DE 35043 Marburg, Germany
    Digestion 71:131-40. 2005
    ..We investigated the effects of the tyrosine kinase inhibitor imatinib (Gleevec) on neuroendocrine tumor cells...
  52. ncbi request reprint Gastric perception thresholds are low and sensory neuropeptide levels high in helicobacter pylori-positive functional dyspepsia
    Hubert Monnikes
    Department of Medicine, Division of Hepatology and Gastroenterology, Charite, Campus Virchow Klinikum, Humboldt Universitat zu Berlin, Germany
    Digestion 71:111-23. 2005
    ..The aim of this study was to assess whether FD patients have altered mucosal concentrations of CGRP and SP, and to investigate whether this is associated with visceral hypersensitivity or H. pylori infection...
  53. ncbi request reprint Expression of the two isoforms of the vesicular monoamine transporter (VMAT1 and VMAT2) in the endocrine pancreas and pancreatic endocrine tumors
    Martin Anlauf
    Department of Molecular Neuroscience, Institute of Anatomy and Cell Biology, Philipps University of Marburg, Marburg, Germany
    J Histochem Cytochem 51:1027-40. 2003
    ..Monoamine storage mediated by VMAT1 in EC cells is apparently maintained in EC cell tumors. In contrast, many insulinomas appear to lose their ability to accumulate monoamines via VMAT2...
  54. ncbi request reprint Pre-therapeutic dosimetry and biodistribution of 86Y-DOTA-Phe1-Tyr3-octreotide versus 111In-pentetreotide in patients with advanced neuroendocrine tumours
    Andreas Helisch
    Department of Nuclear Medicine, University of Mainz, Mainz, Germany
    Eur J Nucl Med Mol Imaging 31:1386-92. 2004
    ....
  55. ncbi request reprint Xenin-immunoreactive cells and extractable xenin in neuroendocrine tumors of duodenal origin
    Gerhard E Feurle
    DRK Krankenhaus Neuwied, Philipps Universitat Marburg, Germany
    Gastroenterology 123:1616-26. 2002
    ..Xenin is a 25-amino acid peptide produced by specific endocrine cells of the duodenal mucosa. We investigated whether xenin is expressed in neuroendocrine tumors...
  56. ncbi request reprint Nephrotoxicity versus anti-tumour efficacy in radiopeptide therapy: facts and myths about the Scylla and Charybdis
    Thomas M Behr
    Eur J Nucl Med Mol Imaging 29:277-9. 2002
  57. ncbi request reprint A novel somatostatin conjugate with a high affinity to all five somatostatin receptor subtypes
    Ulrich Wulbrand
    Clinical Research Unit for Gastrointestinal Endocrinology, Department of Internal Medicine, Philipps University Marburg, Marburg, Germany
    Cancer 94:1293-7. 2002
    ..That is the basis for its use in the treatment of SRS-positive tumors. Radiolabeled SMS analogs can also be used for systemic radiotherapy and for diagnostic investigations...