Martin Walter

Summary

Affiliation: Otto-von-Guericke University
Country: Germany

Publications

  1. doi request reprint Distinguishing specific sexual and general emotional effects in fMRI-subcortical and cortical arousal during erotic picture viewing
    Martin Walter
    Department of Psychiatry, University Hospital, Magdeburg, Germany
    Neuroimage 40:1482-94. 2008
  2. doi request reprint Multistage drug effects of ketamine in the treatment of major depression
    Martin Walter
    Clinical Affective Neuroimaging Laboratory CANLAB, Otto von Guericke University, ZENIT, Leipziger Str 44, 39120, Magdeburg, Germany
    Eur Arch Psychiatry Clin Neurosci 264:S55-65. 2014
  3. doi request reprint High resolution fMRI of subcortical regions during visual erotic stimulation at 7 T
    Martin Walter
    Department of Psychiatry, University Hospital Otto v Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    MAGMA 21:103-11. 2008
  4. doi request reprint The relationship between aberrant neuronal activation in the pregenual anterior cingulate, altered glutamatergic metabolism, and anhedonia in major depression
    Martin Walter
    Department of Psychiatry, Ottovon Guericke University of Magdeburg, Magdeburg, Germany
    Arch Gen Psychiatry 66:478-86. 2009
  5. ncbi request reprint Preceding attention and the dorsomedial prefrontal cortex: process specificity versus domain dependence
    Martin Walter
    Department of Psychiatry, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Hum Brain Mapp 30:312-26. 2009
  6. doi request reprint Modulation of attention network activation under antidepressant agents in healthy subjects
    Heiko Graf
    Department of Psychiatry, Ulm University, Ulm, Germany
    Int J Neuropsychopharmacol 16:1219-30. 2013
  7. doi request reprint Systematic regional variations of GABA, glutamine, and glutamate concentrations follow receptor fingerprints of human cingulate cortex
    Weiqiang Dou
    Biomedical Magnetic Resonance, Otto von Guericke University, 39120 Magdeburg, Germany
    J Neurosci 33:12698-704. 2013
  8. doi request reprint Bridging the gap between the immune and glutamate hypotheses of schizophrenia and major depression: Potential role of glial NMDA receptor modulators and impaired blood-brain barrier integrity
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Magdeburg, Germany
    World J Biol Psychiatry 13:482-92. 2012
  9. doi request reprint Modulation of frontostriatal interaction aligns with reduced primary reward processing under serotonergic drugs
    Birgit Abler
    Department of Psychiatry, University of Ulm, 89075 Ulm, Germany
    J Neurosci 32:1329-35. 2012
  10. doi request reprint Acute schizophrenia is accompanied by reduced T cell and increased B cell immunity
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Germany
    Eur Arch Psychiatry Clin Neurosci 260:509-18. 2010

Collaborators

Detail Information

Publications42

  1. doi request reprint Distinguishing specific sexual and general emotional effects in fMRI-subcortical and cortical arousal during erotic picture viewing
    Martin Walter
    Department of Psychiatry, University Hospital, Magdeburg, Germany
    Neuroimage 40:1482-94. 2008
    ..No differences were found in these effects when comparing females and males. Our findings demonstrate for the first time neural differentiation between emotional and sexual components in the neural network underlying sexual arousal...
  2. doi request reprint Multistage drug effects of ketamine in the treatment of major depression
    Martin Walter
    Clinical Affective Neuroimaging Laboratory CANLAB, Otto von Guericke University, ZENIT, Leipziger Str 44, 39120, Magdeburg, Germany
    Eur Arch Psychiatry Clin Neurosci 264:S55-65. 2014
    ....
  3. doi request reprint High resolution fMRI of subcortical regions during visual erotic stimulation at 7 T
    Martin Walter
    Department of Psychiatry, University Hospital Otto v Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany
    MAGMA 21:103-11. 2008
    ....
  4. doi request reprint The relationship between aberrant neuronal activation in the pregenual anterior cingulate, altered glutamatergic metabolism, and anhedonia in major depression
    Martin Walter
    Department of Psychiatry, Ottovon Guericke University of Magdeburg, Magdeburg, Germany
    Arch Gen Psychiatry 66:478-86. 2009
    ..Major depressive disorder (MDD) is characterized by diverse metabolic and functional abnormalities that occur in, among other regions, the pregenual anterior cingulate cortex (pgACC), a cortical region linked to anhedonia...
  5. ncbi request reprint Preceding attention and the dorsomedial prefrontal cortex: process specificity versus domain dependence
    Martin Walter
    Department of Psychiatry, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Hum Brain Mapp 30:312-26. 2009
    ..This suggests that the anterior and posterior DMPFC is involved in the process of attending mental states while remaining more (posterior DMPFC) or less (anterior DMPFC) independent of the type or domain of the respective stimulus...
  6. doi request reprint Modulation of attention network activation under antidepressant agents in healthy subjects
    Heiko Graf
    Department of Psychiatry, Ulm University, Ulm, Germany
    Int J Neuropsychopharmacol 16:1219-30. 2013
    ..Concurrent alterations of brain regions within a fronto-parietal and cingulo-opercular attention network for top-down control could point to basic neural mechanisms of antidepressant action irrespective of receptor profiles...
  7. doi request reprint Systematic regional variations of GABA, glutamine, and glutamate concentrations follow receptor fingerprints of human cingulate cortex
    Weiqiang Dou
    Biomedical Magnetic Resonance, Otto von Guericke University, 39120 Magdeburg, Germany
    J Neurosci 33:12698-704. 2013
    ....
  8. doi request reprint Bridging the gap between the immune and glutamate hypotheses of schizophrenia and major depression: Potential role of glial NMDA receptor modulators and impaired blood-brain barrier integrity
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Magdeburg, Germany
    World J Biol Psychiatry 13:482-92. 2012
    ..It is not clear, however, whether such changes are associated with corresponding neuroinflammatory responses and disturbances of neurotransmission...
  9. doi request reprint Modulation of frontostriatal interaction aligns with reduced primary reward processing under serotonergic drugs
    Birgit Abler
    Department of Psychiatry, University of Ulm, 89075 Ulm, Germany
    J Neurosci 32:1329-35. 2012
    ....
  10. doi request reprint Acute schizophrenia is accompanied by reduced T cell and increased B cell immunity
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Germany
    Eur Arch Psychiatry Clin Neurosci 260:509-18. 2010
    ..In addition to disease stage or subtype and medication, cigarette smoking and stress are important co-factors...
  11. doi request reprint Disease severity is correlated to tract specific changes of fractional anisotropy in MD and CM thalamus--a DTI study in major depressive disorder
    Annemarie Osoba
    Department of Psychiatry, Otto von Guericke University, Magdeburg, Germany
    J Affect Disord 149:116-28. 2013
    ..Especially thalamic disconnections have been functionally revealed, however, their structural correlates have not been distinctly investigated for its highly diverse subnuclei...
  12. pmc Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Magdeburg, Germany
    J Neuroinflammation 8:94. 2011
    ..These peripheral immune processes may be accompanied by microglial activation in subregions of the anterior cingulate cortex where depression-associated alterations of glutamatergic neurotransmission have been described...
  13. ncbi request reprint Pedophilia is linked to reduced activation in hypothalamus and lateral prefrontal cortex during visual erotic stimulation
    Martin Walter
    Department of Psychiatry, Otto von Guericke University of Magdeburg, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Biol Psychiatry 62:698-701. 2007
    ..Although pedophilic patients are sexually attracted to prepubescent children, they show no sexual interest toward adults. This study aimed to investigate the neural correlates of deficits of sexual and emotional arousal in pedophiles...
  14. doi request reprint The role of hippocampus dysfunction in deficient memory encoding and positive symptoms in schizophrenia
    Kathrin Zierhut
    Department of Psychiatry, Otto von Guericke University of Magdeburg, Germany
    Psychiatry Res 183:187-94. 2010
    ..Declarative memory disturbances, known to substantially contribute to cognitive impairment in schizophrenia, have previously been attributed to prefrontal as well as hippocampal dysfunction...
  15. doi request reprint S100B serum levels are closely correlated with body mass index: an important caveat in neuropsychiatric research
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Germany
    Psychoneuroendocrinology 35:321-4. 2010
    ..In conclusion, physiological S100B levels in humans appear to closely reflect adipose tissue mass, which should therefore be considered as an important confounding factor in clinical studies examining the role of S100B...
  16. doi request reprint Altered task-specific deactivation in the default mode network depends on valence in patients with major depressive disorder
    Bin Zhang
    Department of Psychiatry, Otto von Guericke University, Magdeburg, Germany Clinical Affective Neuroimaging Laboratory, Otto von Guericke University, Magdeburg, Germany Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    J Affect Disord 207:377-383. 2017
    ..Furthermore, MDD patients showed increased resting-state functional connectivity (FC) between the medial prefrontal cortex and other DMN structures...
  17. doi request reprint SSRI-related modulation of sexual functioning is predicted by pre-treatment resting state functional connectivity in healthy men
    Coraline D Metzger
    Department of Psychiatry and Psychotherapy, Centre for Behavioral Brain Sciences, Otto von Guericke University, Magdeburg, Germany
    Arch Sex Behav 42:935-47. 2013
    ....
  18. ncbi request reprint Differential parametric modulation of self-relatedness and emotions in different brain regions
    Georg Northoff
    Department of Psychiatry, University of Magdeburg, Magdeburg, Germany
    Hum Brain Mapp 30:369-82. 2009
    ..hum..
  19. doi request reprint Temporal Dynamics of Antidepressant Ketamine Effects on Glutamine Cycling Follow Regional Fingerprints of AMPA and NMDA Receptor Densities
    Meng Li
    Clinical Affective Neuroimaging Laboratory, Leibniz Institute for Neurobiology, Otto von Guericke University, Magdeburg, Germany
    Neuropsychopharmacology . 2016
    ..Neuropsychopharmacology advance online publication, 19 October 2016; doi:10.1038/npp.2016.184...
  20. ncbi request reprint A spectroscopic approach toward depression diagnosis: local metabolism meets functional connectivity
    Liliana Ramona Demenescu
    Clinical Affective Neuroimaging Laboratory, Leipziger Str 44, 39120, Magdeburg, Germany
    Eur Arch Psychiatry Clin Neurosci . 2016
    ..While causality cannot directly be inferred from such correlation, our finding helps to define a multilevel network of response-predicting regions based on local metabolism and connectivity strength...
  21. pmc Reduced density of glutamine synthetase immunoreactive astrocytes in different cortical areas in major depression but not in bipolar I disorder
    Hans Gert Bernstein
    Department of Psychiatry, University of Magdeburg Magdeburg, Germany
    Front Cell Neurosci 9:273. 2015
    ..2010)...
  22. pmc S100B Serum Levels in Schizophrenia Are Presumably Related to Visceral Obesity and Insulin Resistance
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Leipziger Str 44, 39120 Magdeburg, Germany
    Cardiovasc Psychiatry Neurol 2010:480707. 2010
    ....
  23. pmc Erotic stimulus processing under amisulpride and reboxetine: a placebo-controlled fMRI study in healthy subjects
    Heiko Graf
    Department of Psychiatry III, Ulm University, Ulm, Germany Drs Graf, Wiegers, Gron, and Abler Department of Psychiatry, Otto von Guericke University, Magdeburg, Germany Drs Metzger and Walter Leibniz Institute for Neurobiology, Magdeburg, Germany Drs Metzger and Walter
    Int J Neuropsychopharmacol 18:. 2014
    ..2011). Here, we studied the impact of noradrenergic and antidopaminergic medication on neural correlates of visual sexual stimulation in a new sample of subjects...
  24. doi request reprint Altered functional connectivity density in major depressive disorder at rest
    Bin Zhang
    Department of Psychiatry, Otto von Guericke University, Magdeburg, Germany
    Eur Arch Psychiatry Clin Neurosci 266:239-48. 2016
    ..This implies the importance of FC measures in the investigation of brain pathophysiology in depression. ..
  25. doi request reprint The separation of Gln and Glu in STEAM: a comparison study using short and long TEs/TMs at 3 and 7 T
    Weiqiang Dou
    Faculty for Natural Sciences, Biomedical Magnetic Resonance, Otto von Guericke University, ZENIT Building, Leipziger Str 44, 39120, Magdeburg, Germany
    MAGMA 28:395-405. 2015
    ..We applied a short TE/TM (20/10 ms) for a high signal-to-noise-ratio and a field-specific long TE/TM (3 T: 72/6 ms; 7 T: 74/68 ms) for optimal Gln and Glu separation of the Carbon-4 proton resonances...
  26. doi request reprint Automatic voxel positioning for MRS at 7 T
    Weiqiang Dou
    Faculty for Natural Sciences, Biomedical Magnetic Resonance, Otto von Guericke University, ZENIT Building, Leipziger Str 44, 39120, Magdeburg, Germany
    MAGMA 28:259-70. 2015
    ..The purpose of this study was to test, for the first time, whether spectroscopy voxels could be positioned automatically with high accuracy and reproducibility in ultrahigh-field longitudinal magnetic resonance spectroscopy (MRS) studies...
  27. doi request reprint Distribution of immunoreactive glutamine synthetase in the adult human and mouse brain. Qualitative and quantitative observations with special emphasis on extra-astroglial protein localization
    Hans Gert Bernstein
    Department of Psychiatry, Otto von Guericke University, Faculty of Medicine, Magdeburg, Germany Electronic address
    J Chem Neuroanat 61:33-50. 2014
    ..e. neuronal nitric oxide synthase expressing) neurons. Possible functional implications of an extra-astrocytic localization of glutamine synthetase are discussed. ..
  28. doi request reprint Increased prevalence of diverse N-methyl-D-aspartate glutamate receptor antibodies in patients with an initial diagnosis of schizophrenia: specific relevance of IgG NR1a antibodies for distinction from N-methyl-D-aspartate glutamate receptor encephalitis
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Magdeburg, Germany
    JAMA Psychiatry 70:271-8. 2013
    ....
  29. ncbi request reprint GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI
    Georg Northoff
    Department of Psychiatry, Otto von Guericke University Magdeburg, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Nat Neurosci 10:1515-7. 2007
    ..Our findings show that default-mode network negative BOLD responses during emotions are mediated by GABA...
  30. doi request reprint Preprocessing strategy influences graph-based exploration of altered functional networks in major depression
    Viola Borchardt
    Department of Behavioral Neurology, Leibniz Institute for Neurobiology, Magdeburg, Germany
    Hum Brain Mapp 37:1422-42. 2016
    ..Our study offers an overview of consequences of methodological decisions and which neurobiological characteristics of MDD they implicate, adding further caution to this rapidly growing field...
  31. doi request reprint Dissociation of glutamate and cortical thickness is restricted to regions subserving trait but not state markers in major depressive disorder
    Meng Li
    Department of Neurology, Otto von Guericke University, Magdeburg, Germany
    J Affect Disord 169:91-100. 2014
    ..We aimed to investigate structural and biochemical changes and their relationship in the pregenual ACC (pgACC), dorsal ACC (dACC) in MDD...
  32. pmc Local and Global Resting State Activity in the Noradrenergic and Dopaminergic Pathway Modulated by Reboxetine and Amisulpride in Healthy Subjects
    Coraline D Metzger
    Department of Psychiatry and Psychotherapy, Otto von Guericke University, Magdeburg, Germany Drs Metzger and Walter Department of Psychiatry, University of Ulm, Germany Drs Wiegers, Abler, and Graf Leibniz Institute for Neurobiology, Magdeburg, Germany Drs Metzger and Walter Institute of Cognitive Neurology and Dementia Research IKND, Otto von Guericke University, Magdeburg, Germany Dr Metzger German Center for Neurodegenerative Diseases DZNE, Magdeburg, Germany Dr Metzger
    Int J Neuropsychopharmacol 19:. 2015
    ....
  33. doi request reprint Serotonergic antidepressants decrease hedonic signals but leave learning signals in the nucleus accumbens unaffected
    Heiko Graf
    aDepartment of Psychiatry and Psychotherapy III, Ulm University, Ulm bDepartment of Psychiatry, Otto von Guericke University Magdeburg cGerman Center for Neurodegenerative Diseases DZNE dLeibniz Institute for Neurobiology, Magdeburg, Germany
    Neuroreport 27:18-22. 2016
    ....
  34. ncbi request reprint Disruption of glutamate-glutamine-GABA cycle significantly impacts on suicidal behaviour: survey of the literature and own findings on glutamine synthetase
    Hans Gert Bernstein
    Department of Psychiatry, University of Magdeburg, Leipziger Str 44, D 39120Magdeburg, Germany
    CNS Neurol Disord Drug Targets 12:900-13. 2013
    ....
  35. doi request reprint Preferential networks of the mediodorsal nucleus and centromedian-parafascicular complex of the thalamus--a DTI tractography study
    Ulf Eckert
    Department of Psychiatry, Otto von Guericke University, Magdeburg, Germany
    Hum Brain Mapp 33:2627-37. 2012
    ....
  36. doi request reprint Brain parcellation choice affects disease-related topology differences increasingly from global to local network levels
    Anton Lord
    Leibniz Institute for Neurobiology, Magdeburg, Saxony Anhalt, Germany Clinical Affective Neuroimaging Laboratory, Magdeburg, Saxony Anhalt, Germany
    Psychiatry Res 249:12-9. 2016
    ..Therefore, the impact of parcellation choice on specific group differences varies depending on the level of network organization. ..
  37. doi request reprint Graph theory reveals hyper-functionality in visual cortices of Seasonal Affective Disorder patients
    Viola Borchardt
    Leibniz Institute for Neurobiology, Magdeburg, Germany
    World J Biol Psychiatry 16:123-34. 2015
    ..Studies examining SAD have found disturbances between the molecular and connectivity scales. The aim of the study was to explore changes in functional connectivity typical for SAD...
  38. pmc Neural correlates of antidepressant-related sexual dysfunction: a placebo-controlled fMRI study on healthy males under subchronic paroxetine and bupropion
    Birgit Abler
    Department of Psychiatry, University of Ulm, Ulm, Germany
    Neuropsychopharmacology 36:1837-47. 2011
    ..Drug effects on these regions may be part of the mechanism underlying SSRI-related sexual dysfunction. Increased activation under bupropion may point to an opposite effect that may relate to the lack of impaired sexual functioning...
  39. doi request reprint Evidence for superior neurobiological and behavioral inhibitory control abilities in non-offending as compared to offending pedophiles
    Christian Kargel
    Division of Forensic Psychiatry, Department of Psychiatry, Psychotherapy and Preventive Medicine, LWL University Hospital Bochum, Alexandrinenstraße 1 3, Bochum, 44791, Germany
    Hum Brain Mapp . 2016
    ..Hum Brain Mapp, 2016. © 2016 Wiley Periodicals, Inc...
  40. pmc Altered baseline brain activity differentiates regional mechanisms subserving biological and psychological alterations in obese men
    Bin Zhang
    1 Department of Anatomy, Tianjin Medical University, Tianjin, China 2 Department of Psychiatry and Psychotherapy, University of Magdeburg, Magdeburg, Germany 3 Clinical Affective Neuroimaging Laboratory, University of Magdeburg, Magdeburg, Germany 4 Leibniz Institute for Neurobiology, Magdeburg, Germany
    Sci Rep 5:11563. 2015
    ..These results indicated that both precuneus and dACC may play an important role in eating behavior. While precuneus rather seemed to mediate subjective satiety, dACC levels rather reflected indirect measures of glucose utilization. ..
  41. doi request reprint A new pathophysiological aspect of S100B in schizophrenia: potential regulation of S100B by its scavenger soluble RAGE
    Johann Steiner
    Department of Psychiatry, University of Magdeburg, Germany
    Biol Psychiatry 65:1107-10. 2009
    ..Our study focused on its scavenger, soluble receptor for advanced glycation end products (sRAGE). Given the benefits of sRAGE in metabolic and inflammatory diseases, we hypothesized a similar effect in schizophrenia...