Affiliation: Max Planck Institute for Molecular Genetics
- FoxP2 expression in avian vocal learners and non-learnersSebastian Haesler
Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
J Neurosci 24:3164-75. 2004..We conclude that differential expression of FoxP2 in avian vocal learners might be associated with vocal plasticity...
- Genetic components of vocal learningConstance Scharff
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
Ann N Y Acad Sci 1016:325-47. 2004..These latter regions also express FoxP2 in mammals and reptiles. We conclude that FoxP2 is important for the building and function of brain pathways including, but not limited to, those essential for learned vocal communication...
- An evolutionary perspective on FoxP2: strictly for the birds?Constance Scharff
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany Freie Universität Berlin, Department of Animal Behavior, Grunewaldstrasse 34, 12165 Berlin, Germany
Curr Opin Neurobiol 15:694-703. 2005..This suggests that FoxP2 plays important roles both in the development of neural circuits and in the postnatal behaviors they mediate...
- Recruitment of FoxP2-expressing neurons to area X varies during song developmentChristelle Rochefort
Laboratory of Animal Behavior, Freie Universitat Berlin, Takustr 6, 14195 Berlin, Germany
Dev Neurobiol 67:809-17. 2007..Together these results raise the possibility that neuronal recruitment and FoxP2 expression in Area X are associated with vocal learning...
- Incomplete and inaccurate vocal imitation after knockdown of FoxP2 in songbird basal ganglia nucleus Area XSebastian Haesler
Max Planck Institute for Molecular Genetics, Berlin, Germany
PLoS Biol 5:e321. 2007..Our findings provide the first example of a functional gene analysis in songbirds and suggest that normal auditory-guided vocal motor learning requires FoxP2...
- Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardationVera M Kalscheuer
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, D 14195 Berlin, Germany
Nat Genet 35:313-5. 2003..PQBP1 has previously been implicated in the pathogenesis of polyglutamine expansion diseases. Our findings link this gene to XLMR and shed more light on the pathogenesis of this common disorder...
- Calbindin expression in developing striatum of zebra finches and its relation to the formation of area XElena Garcia-Calero
Department of Animal Behavior, Institute of Biology, Freie Universitat Berlin, Berlin, Germany
J Comp Neurol 521:326-41. 2013..We discuss possible reasons for CB expression in MSNs in songbirds and mammals, but not described in chicken striatum...
- Early developmental stress negatively affects neuronal recruitment to avian song system nucleus HVCMariam Honarmand
Department of Animal Behavior, Freie Universit t, Berlin, Germany
Dev Neurobiol . 2015..Our study shows that even transitory developmental stress can have negative consequences on the cellular processes underlying the development of neural circuits. © 2015 Wiley Periodicals, Inc. Develop Neurobiol, 2015...
- Gene expression changes in the course of neural progenitor cell differentiationUlf Gurok
Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
J Neurosci 24:5982-6002. 2004..Our results provide new insights into the genetic program of neural progenitor differentiation and give strong hints to as yet unknown cellular communications within the adult subventricular zone stem cell niche...
- FoxP2 in songbirdsSandra Wohlgemuth
Department Animal Behavior, Freie Universitat Berlin, Takustr 6, 14195 Berlin, Germany
Curr Opin Neurobiol 28:86-93. 2014..This will be key to further unravel how FoxP2 influences synaptic function and thereby contributes to auditory guided vocal motor behavior in the songbird model. ..
- The use of network analysis to study complex animal communication systems: a study on nightingale songMichael Weiss
Institute of Biology, Animal Behaviour Group, Free University Berlin, Berlin, Germany, Department of Exposition, Unit Epidemiology, Statistics and Mathematical Modelling, Federal Institute for Risk Assessment BfR, Berlin, Germany
Proc Biol Sci 281:20140460. 2014..Network approaches provide biologically meaningful parameters to describe the song structure of species with extremely large repertoires and complex rules of song retrieval. ..
- Neurogenetics of birdsongConstance Scharff
Freie Universitat Berlin, Institute of Biology, Takustraße 6, 14195 Berlin, Germany
Curr Opin Neurobiol 23:29-36. 2013..More recently, the emerging field of birdsong neurogenetics has advanced the way we think about genetic contributions to communication, mechanistically and conceptually...
- The songbird syrinx morphome: a three-dimensional, high-resolution, interactive morphological map of the zebra finch vocal organDaniel N Düring
Verhaltensbiologie, Freie Universitat Berlin, Takustrasse 6, 14195 Berlin, Germany
BMC Biol 11:1. 2013..However, how neural impulses are translated into the precise motor behavior of the complex vocal organ (syrinx) to create song is poorly understood. First and foremost, we lack a detailed understanding of syringeal morphology...
- Evo-devo, deep homology and FoxP2: implications for the evolution of speech and languageConstance Scharff
Department of Animal Behavior, Freie Universitat Berlin, Takustr 6, 14195 Berlin, Germany
Philos Trans R Soc Lond B Biol Sci 366:2124-40. 2011..The emerging picture can help us understand how complex cognitive traits can 'descend with modification'...
- HVC interneurons are not renewed in adult male zebra finchesSophie Scotto-Lomassese
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, Berlin, Germany
Eur J Neurosci 25:1663-8. 2007..This implies that the sum of HVC(IN) expressing the different calcium-binding proteins constitute all inhibitory HVC(IN). Together these results strongly suggest that only HVC(RA) are recruited into the adult HVC...
- Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and languageStephanie A White
Department of Physiological Science, University of California, Los Angeles, California 90095, USA
J Neurosci 26:10376-9. 2006..Below, we describe genetic through behavioral techniques used currently to investigate FoxP2 in birds, rodents, and humans for discovery of the neural bases of vocal learning and language...
- A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genesKazuhiro Wada
Department of Neurobiology and Duke Bioinformatics Shared Resource, Duke University Medical Center, Durham, NC 27710, USA
Proc Natl Acad Sci U S A 103:15212-7. 2006..This publicly accessible resource http://songbirdtranscriptome.net can now be used to study molecular neuroethological mechanisms of behavior...