Teymuras V Kurzchalia

Summary

Affiliation: Max Planck Institute of Molecular Cell Biology and Genetics
Country: Germany

Publications

  1. pmc Anthrax toxin rafts into cells
    Teymuras Kurzchalia
    Max Planck Institute for Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    J Cell Biol 160:295-6. 2003
  2. ncbi request reprint Why do worms need cholesterol?
    Teymuras V Kurzchalia
    Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, D 01307, Germany
    Nat Cell Biol 5:684-8. 2003
  3. doi request reprint Methylation of the sterol nucleus by STRM-1 regulates dauer larva formation in Caenorhabditis elegans
    J Thomas Hannich
    Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany
    Dev Cell 16:833-43. 2009
  4. doi request reprint LET-767 is required for the production of branched chain and long chain fatty acids in Caenorhabditis elegans
    Eugeni V Entchev
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    J Biol Chem 283:17550-60. 2008
  5. pmc Survival strategies of a sterol auxotroph
    Maria Carvalho
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    Development 137:3675-85. 2010
  6. pmc Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
    Vitali Matyash
    Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    J Lipid Res 49:1137-46. 2008
  7. doi request reprint Two cytochrome P450s in Caenorhabditis elegans are essential for the organization of eggshell, correct execution of meiosis and the polarization of embryo
    Gaspare Benenati
    Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany
    Mech Dev 126:382-93. 2009
  8. doi request reprint Trehalose renders the dauer larva of Caenorhabditis elegans resistant to extreme desiccation
    Cihan Erkut
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany
    Curr Biol 21:1331-6. 2011
  9. pmc Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation
    Cihan Erkut
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    PLoS ONE 8:e82473. 2013
  10. pmc Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16
    Vitali Matyash
    Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany
    PLoS Biol 2:e280. 2004

Collaborators

  • Howard Riezman
  • Vyacheslav Zagoriy
  • Andrej Shevchenko
  • Bianca Habermann
  • Suzanne Eaton
  • Satyajit Mayor
  • Gerhard Liebisch
  • Christoph Thiele
  • Robert G Parton
  • Gagan D Gupta
  • Cihan Erkut
  • Eugeni V Entchev
  • Vitali Matyash
  • Dominik Schwudke
  • Maria Carvalho
  • Sider Penkov
  • Isabelle Riezman
  • J Thomas Hannich
  • Gaspare Benenati
  • Fanny Mende
  • Hans Joachim Knölker
  • Matthew Kirkham
  • Agathi Papanikolaou
  • John F Hancock
  • Bruce D Wyse
  • Sebastian Boland
  • Andrej Vasilj
  • Karim Fahmy
  • Hassan Khesbak
  • Daniela Vorkel
  • Jean Marc Verbavatz
  • Gautam Dey
  • Wilhelm Palm
  • Julio L Sampaio
  • Hristio Boytchev
  • Rene Martin
  • Thomas Müller-Reichert
  • Gabriele Theumer
  • Aliona Bogdanova
  • Lin Zhu
  • Savvas Christoforidis
  • Carol Murphy
  • Marek Drab
  • Thomais Papamarcaki
  • Alexandra Papafotika
  • Akikazu Fujita
  • Orestes Tsolas
  • Deepak K Sharma
  • Michael Kasper
  • Richard E Pagano
  • Rahul Chadda
  • Susan J Nixon
  • Samuel Ward
  • Arndt W Schmidt
  • Michaela Wilsch-Bräuninger
  • Cornelia Muncke
  • Walter G Thomas
  • Susan Nixon
  • Isabel C Morrow
  • Hongwei Qian
  • Ian A Prior

Detail Information

Publications16

  1. pmc Anthrax toxin rafts into cells
    Teymuras Kurzchalia
    Max Planck Institute for Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    J Cell Biol 160:295-6. 2003
    ..In this issue, Abrami et al. (2003) demonstrate that toxin oligomerization clusters the anthrax receptor into lipid rafts and this complex is internalized via the clathrin-dependent pathway...
  2. ncbi request reprint Why do worms need cholesterol?
    Teymuras V Kurzchalia
    Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, D 01307, Germany
    Nat Cell Biol 5:684-8. 2003
    ..Instead, its most probable signalling functions are to control molting and induce a specialized non-feeding larval stage, although no cholesterol-derived signalling molecule has yet been identified for these or any other functions...
  3. doi request reprint Methylation of the sterol nucleus by STRM-1 regulates dauer larva formation in Caenorhabditis elegans
    J Thomas Hannich
    Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany
    Dev Cell 16:833-43. 2009
    ..Moreover, the C-4 sterol nucleus methylation catalyzed by STRM-1 is unique to nematodes and thus could be a target for therapeutic strategies against parasitic nematode infections...
  4. doi request reprint LET-767 is required for the production of branched chain and long chain fatty acids in Caenorhabditis elegans
    Eugeni V Entchev
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    J Biol Chem 283:17550-60. 2008
    ..elegans required for the bulk production of monomethyl branched and long chain fatty acids, and the developmental arrest in let-767 (RNAi) worms is caused by the deficiency of the former...
  5. pmc Survival strategies of a sterol auxotroph
    Maria Carvalho
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    Development 137:3675-85. 2010
    ..These changes allow survival, but not growth, when membrane sterol levels are low. This relationship between sterols and sphingolipids could be an ancient and conserved principle of membrane homeostasis...
  6. pmc Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
    Vitali Matyash
    Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    J Lipid Res 49:1137-46. 2008
    ..Rigorous testing demonstrated that the MTBE protocol delivers similar or better recoveries of species of most all major lipid classes compared with the "gold-standard" Folch or Bligh and Dyer recipes...
  7. doi request reprint Two cytochrome P450s in Caenorhabditis elegans are essential for the organization of eggshell, correct execution of meiosis and the polarization of embryo
    Gaspare Benenati
    Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany
    Mech Dev 126:382-93. 2009
    ..Using a complementation with lipid extracts, we show that POD-7/POD-8 function together with a NADPH cytochrome P450 reductase, coded by emb-8, and are involved in the production of lipid(s) required for eggshell formation...
  8. doi request reprint Trehalose renders the dauer larva of Caenorhabditis elegans resistant to extreme desiccation
    Cihan Erkut
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany
    Curr Biol 21:1331-6. 2011
    ..By means of infrared spectroscopy, we can now distinguish a "dry, yet alive" larva from a "dry and dead" one...
  9. pmc Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation
    Cihan Erkut
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    PLoS ONE 8:e82473. 2013
    ..Remarkably, this response is specific and involves a small number of functional pathways, which represent the generic toolkit for anhydrobiosis in plants and animals. ..
  10. pmc Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16
    Vitali Matyash
    Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany
    PLoS Biol 2:e280. 2004
    ..This hormonal control of DAF-16 activation is, however, independent of insulin signalling and has no influence on life span...
  11. doi request reprint The C. elegans dauer larva as a paradigm to study metabolic suppression and desiccation tolerance
    Cihan Erkut
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307, Dresden, Germany
    Planta 242:389-96. 2015
    ..These are increased glyoxalase activity, polyamine and polyunsaturated fatty acid biosynthesis. All these pathways may constitute a generic toolbox of anhydrobiosis, which is possibly conserved between animals and plants...
  12. ncbi request reprint Requirement of sterols in the life cycle of the nematode Caenorhabditis elegans
    Eugeni V Entchev
    MPI for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    Semin Cell Dev Biol 16:175-82. 2005
    ..Investigations on C. elegans could provide information on the etiology of human diseases that display defects in the transport or metabolism of sterols...
  13. pmc Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles
    Matthew Kirkham
    Institute for Molecular Bioscience, University of Queensland, Queensland 4072, Australia
    J Cell Biol 168:465-76. 2005
    ..These carriers contained GPI-anchored proteins and fluid phase markers and represented the major vehicles mediating CTB uptake in both WT and caveolae-null cells...
  14. ncbi request reprint Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane
    Bruce D Wyse
    Department of Molecular and Cellular Pathology, University of Queensland, Brisbane, Queensland, Australia
    J Biol Chem 278:23738-46. 2003
    ..Caveolin therefore acts as a molecular chaperone rather than a plasma membrane scaffold for AT1-R...
  15. ncbi request reprint Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39
    Agathi Papanikolaou
    Laboratory of Biological Chemistry, Medical School, University of Ioannina, 45110 Ioannina, Greece
    J Biol Chem 280:26406-14. 2005
    ..These data suggest a functional link between the localization of CD39 in cholesterol-rich domains of the membrane and its role in thromboregulation...