Thomas Kessler

Summary

Affiliation: Max Planck Institute for Molecular Genetics
Country: Germany

Publications

  1. pmc Integrative analysis of cancer-related signaling pathways
    Thomas Kessler
    Systems Biology Group, Department Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    Front Physiol 4:124. 2013
  2. pmc Cleavage of Armadillo/beta-catenin by the caspase DrICE in Drosophila apoptotic epithelial cells
    Thomas Kessler
    Institut fur Genetik, Heinrich Heine Universitat, Dusseldorf, Germany
    BMC Dev Biol 9:15. 2009
  3. doi request reprint Network and systems biology: essential steps in virtualising drug discovery and development
    Christoph Wierling
    Alacris Theranostics GmbH, Berlin, Germany Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    Drug Discov Today Technol 15:33-40. 2015
  4. pmc Modeling of miRNA and drug action in the EGFR signaling pathway
    Jian Li
    Department Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    PLoS ONE 7:e30140. 2012
  5. pmc Proteomic and functional analysis of the mitotic Drosophila centrosome
    Hannah Müller
    Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    EMBO J 29:3344-57. 2010

Collaborators

Detail Information

Publications5

  1. pmc Integrative analysis of cancer-related signaling pathways
    Thomas Kessler
    Systems Biology Group, Department Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    Front Physiol 4:124. 2013
    ..Furthermore, it allows to identify common changes in network module activity of those cancer samples...
  2. pmc Cleavage of Armadillo/beta-catenin by the caspase DrICE in Drosophila apoptotic epithelial cells
    Thomas Kessler
    Institut fur Genetik, Heinrich Heine Universitat, Dusseldorf, Germany
    BMC Dev Biol 9:15. 2009
    ..Since Armadillo/beta-catenin (Arm) is a major regulator of cadherin-mediated adhesion, we analyzed the mechanisms of Arm proteolysis in apoptosis...
  3. doi request reprint Network and systems biology: essential steps in virtualising drug discovery and development
    Christoph Wierling
    Alacris Theranostics GmbH, Berlin, Germany Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    Drug Discov Today Technol 15:33-40. 2015
    ..In doing so, we lay the foundations for truly personalised therapy, as well as a far-reaching virtualisation of drug discovery and development in oncology and other areas of medicine. ..
  4. pmc Modeling of miRNA and drug action in the EGFR signaling pathway
    Jian Li
    Department Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    PLoS ONE 7:e30140. 2012
    ....
  5. pmc Proteomic and functional analysis of the mitotic Drosophila centrosome
    Hannah Müller
    Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    EMBO J 29:3344-57. 2010
    ..In total, we assigned novel centrosome-related functions to 24 proteins and confirmed 13 of these in human cells...