Alexander Zipprich

Summary

Affiliation: Martin Luther University
Country: Germany

Publications

  1. ncbi Subclinical ascites defines an intermediate stage between compensated and decompensated cirrhosis
    A Zipprich
    First Department of Internal Medicine, Martin Luther University Halle Wittenberg, Halle, Germany
    Z Gastroenterol 50:996-1001. 2012
  2. pmc Prognostic indicators of survival in patients with compensated and decompensated cirrhosis
    Alexander Zipprich
    Department of Internal Medicine I, Martin Luther University Halle Wittenberg, Halle, Germany
    Liver Int 32:1407-14. 2012
  3. doi Incorporating indocyanin green clearance into the Model for End Stage Liver Disease (MELD-ICG) improves prognostic accuracy in intermediate to advanced cirrhosis
    Alexander Zipprich
    Department of Internal Medicine I, Martin Luther University Halle Wittenberg, Ernst Grube Strasse 40, Halle Saale, Germany
    Gut 59:963-8. 2010
  4. ncbi Hemodynamics in the isolated cirrhotic liver
    Alexander Zipprich
    First Department of Medicine, Martin Luther University Halle Wittenberg, Halle, Germany
    J Clin Gastroenterol 41:S254-8. 2007
  5. pmc A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver
    Alexander Zipprich
    Digestive Disease Section, Yale University School of Medicine, New Haven, CT, USA
    Liver Int 30:988-94. 2010
  6. doi Comparison of balloon vs. straight catheter for the measurement of portal hypertension
    A Zipprich
    Department of Internal Medicine I, Martin Luther University Halle Wittenberg, Halle Saale, SA, Germany
    Aliment Pharmacol Ther 32:1351-6. 2010
  7. doi The role of hepatic arterial flow on portal venous and hepatic venous wedged pressure in the isolated perfused CCl4-cirrhotic liver
    Alexander Zipprich
    Digestive Disease Section, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Physiol Gastrointest Liver Physiol 295:G197-G202. 2008
  8. doi Nitric oxide and vascular remodeling modulate hepatic arterial vascular resistance in the isolated perfused cirrhotic rat liver
    Alexander Zipprich
    Digestive Disease Section, Yale University School of Medicine, New Haven, CT, USA
    J Hepatol 49:739-45. 2008
  9. ncbi Functional significance of hepatic arterial flow reserve in patients with cirrhosis
    Alexander Zipprich
    First Department of Medicine, Martin Luther University Halle Wittenberg, Germany
    Hepatology 37:385-92. 2003
  10. pmc Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition
    Muhammad A Sohail
    Section of Digestive Diseases, Yale University, New Haven, CT 06520 8019, USA
    Hepatology 49:185-94. 2009

Collaborators

Detail Information

Publications12

  1. ncbi Subclinical ascites defines an intermediate stage between compensated and decompensated cirrhosis
    A Zipprich
    First Department of Internal Medicine, Martin Luther University Halle Wittenberg, Halle, Germany
    Z Gastroenterol 50:996-1001. 2012
    ..The aim of the study was to investigate the prognostic relevance of subclinical ascites detected by ultrasound in comparison to absent or clinically detectable ascites in patients with cirrhosis...
  2. pmc Prognostic indicators of survival in patients with compensated and decompensated cirrhosis
    Alexander Zipprich
    Department of Internal Medicine I, Martin Luther University Halle Wittenberg, Halle, Germany
    Liver Int 32:1407-14. 2012
    ..The objectives of this study were (a) to analyse survival of the different stages and substages of cirrhosis and (b) to examine the prognostic value of the hepatic venous pressure gradient (HVPG) at each of the stages...
  3. doi Incorporating indocyanin green clearance into the Model for End Stage Liver Disease (MELD-ICG) improves prognostic accuracy in intermediate to advanced cirrhosis
    Alexander Zipprich
    Department of Internal Medicine I, Martin Luther University Halle Wittenberg, Ernst Grube Strasse 40, Halle Saale, Germany
    Gut 59:963-8. 2010
    ..However, other complications of cirrhosis are not reflected. This study investigates whether quantitative liver function tests predict survival and increase prognostic accuracy of the MELD...
  4. ncbi Hemodynamics in the isolated cirrhotic liver
    Alexander Zipprich
    First Department of Medicine, Martin Luther University Halle Wittenberg, Halle, Germany
    J Clin Gastroenterol 41:S254-8. 2007
    ..This suggests different availabilities of NO in the intrahepatic circulation with preserved production in the presinusoidal area and impaired production in the sinusoidal/postsinusoidal area...
  5. pmc A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver
    Alexander Zipprich
    Digestive Disease Section, Yale University School of Medicine, New Haven, CT, USA
    Liver Int 30:988-94. 2010
    ..The aim of our study was to identify the signalling pathway responsible for the decreased hepatic arterial resistance in cirrhotic livers...
  6. doi Comparison of balloon vs. straight catheter for the measurement of portal hypertension
    A Zipprich
    Department of Internal Medicine I, Martin Luther University Halle Wittenberg, Halle Saale, SA, Germany
    Aliment Pharmacol Ther 32:1351-6. 2010
    ..Two methods are available using either a straight or a balloon catheter, but have never been compared head-to-head...
  7. doi The role of hepatic arterial flow on portal venous and hepatic venous wedged pressure in the isolated perfused CCl4-cirrhotic liver
    Alexander Zipprich
    Digestive Disease Section, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Physiol Gastrointest Liver Physiol 295:G197-G202. 2008
    ..77, P < 0.001). In conclusion, increases and decreases in HAF lead to respective changes in PVPP and WHVP. This suggests a direct influence of HAF on PVPP and WHVP most likely due to changes in sinusoidal perfusion...
  8. doi Nitric oxide and vascular remodeling modulate hepatic arterial vascular resistance in the isolated perfused cirrhotic rat liver
    Alexander Zipprich
    Digestive Disease Section, Yale University School of Medicine, New Haven, CT, USA
    J Hepatol 49:739-45. 2008
    ..Hepatic arterial resistance is modulated by the hepatic arterioles but the role of NO and vascular remodeling in hepatic arterial resistance in cirrhosis is unknown...
  9. ncbi Functional significance of hepatic arterial flow reserve in patients with cirrhosis
    Alexander Zipprich
    First Department of Medicine, Martin Luther University Halle Wittenberg, Germany
    Hepatology 37:385-92. 2003
    ..The effect does not depend directly on hepatic arterial macroperfusion and is observed preferentially in patients with decompensated disease...
  10. pmc Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition
    Muhammad A Sohail
    Section of Digestive Diseases, Yale University, New Haven, CT 06520 8019, USA
    Hepatology 49:185-94. 2009
    ..We propose that adenosine is a physiological inhibitor of the Rho pathway in HSCs with functional consequences, including loss of HSC contraction...
  11. doi Serum Ferritin in Patients With Cirrhosis is Associated With Markers of Liver Insufficiency and Circulatory Dysfunction, but Not of Portal Hypertension
    Cristina Ripoll
    First Department of Internal Medicine, Martin Luther University Halle Wittenberg, Halle Saale, Germany
    J Clin Gastroenterol 49:784-9. 2015
    ..Iron overload is an increasingly recognized phenomenon in nonhemochromatosis cirrhosis. To evaluate the relationship between iron overload and liver insufficiency and portal hypertension...
  12. pmc Hepatic arterial vasodilation is independent of portal hypertension in early stages of cirrhosis
    Miriam Moeller
    First Department of Internal Medicine, Martin Luther University Halle Wittenberg, Halle Saale, Germany
    PLoS ONE 10:e0121229. 2015
    ..In cirrhosis with elevated portal pressure, the vascular resistance of the hepatic artery is decreased. Whether this lower resistance of the hepatic artery is a consequence of portal hypertension or not remains unknown...