Kathrin Reichwald

Summary

Affiliation: Leibniz Institute for Age Research
Country: Germany

Publications

  1. pmc Strong population genetic structuring in an annual fish, Nothobranchius furzeri, suggests multiple savannah refugia in southern Mozambique
    Veronika Bartáková
    Institute of Vertebrate Biology, Academy of Sciences of the Czech Republic, Květná 8, Brno 603 65, Czech Republic
    BMC Evol Biol 13:196. 2013
  2. pmc High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research
    Kathrin Reichwald
    Leibniz Institute for Age Research Fritz Lipmann Institute, Beutenbergstr, 07745 Jena, Germany
    Genome Biol 10:R16. 2009
  3. pmc Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa
    Timo Dirk Müller
    Department of Child and Adolescent Psychiatry, University of Duisburg Essen, Essen, Germany
    Child Adolesc Psychiatry Ment Health 2:33. 2008
  4. pmc Chicken ovalbumin upstream promoter transcription factor II regulates uncoupling protein 3 gene transcription in Phodopus sungorus
    Tobias Fromme
    Department of Animal Physiology, Faculty of Biology, Philipps University, D 35043 Marburg, Germany
    BMC Mol Biol 8:1. 2007
  5. pmc The transcript catalogue of the short-lived fish Nothobranchius furzeri provides insights into age-dependent changes of mRNA levels
    Andreas Petzold
    Genome Analysis, Leibniz Institute for Age Research Fritz Lipmann Institute, Beutenbergstr 11, Jena 07745, Germany
    BMC Genomics 14:185. 2013
  6. doi request reprint Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri
    Nils Hartmann
    Department of Molecular Genetics, Leibniz Institute for Age Research Fritz Lipmann Institute FLI, Beutenbergstrasse 11, Jena, Germany
    Aging Cell 10:824-31. 2011
  7. pmc Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1
    Stefanie Stepanow
    Genome Analysis, Leibniz Institute for Age Research, Jena, Germany
    PLoS ONE 6:e17711. 2011
  8. ncbi request reprint Method for preparing single-stranded DNA templates for Pyrosequencing using vector ligation and universal biotinylated primers
    Marco Groth
    Genome Analysis, Leibniz Institute for Age Research Fritz Lipmann Institute, 07745 Jena, Germany
    Anal Biochem 356:194-201. 2006
  9. doi request reprint Absence of replicative senescence in cultured cells from the short-lived killifish Nothobranchius furzeri
    Michael Graf
    Molecular Genetics, Leibniz Institute for Age Research, Fritz Lipmann Institute, Beutenbergstr 11, 07745 Jena, Germany
    Exp Gerontol 48:17-28. 2013
  10. pmc Parallel evolution of senescence in annual fishes in response to extrinsic mortality
    Eva Terzibasi Tozzini
    Fritz Lipmann Institute for Age Research, Leibniz Institute, Jena, Germany
    BMC Evol Biol 13:77. 2013

Collaborators

Detail Information

Publications14

  1. pmc Strong population genetic structuring in an annual fish, Nothobranchius furzeri, suggests multiple savannah refugia in southern Mozambique
    Veronika Bartáková
    Institute of Vertebrate Biology, Academy of Sciences of the Czech Republic, Květná 8, Brno 603 65, Czech Republic
    BMC Evol Biol 13:196. 2013
    ..Here, we analysed the genetic structure, diversity, historical demography and temporal patterns of divergence in natural populations of N. furzeri across its entire distribution range...
  2. pmc High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research
    Kathrin Reichwald
    Leibniz Institute for Age Research Fritz Lipmann Institute, Beutenbergstr, 07745 Jena, Germany
    Genome Biol 10:R16. 2009
    ..Treatment with resveratrol and low temperature significantly extends the maximum life span. These features make N. furzeri a promising new vertebrate model for age research...
  3. pmc Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa
    Timo Dirk Müller
    Department of Child and Adolescent Psychiatry, University of Duisburg Essen, Essen, Germany
    Child Adolesc Psychiatry Ment Health 2:33. 2008
    ..The aim of this study was to analyse whether nucleotide sequence variations in the CNR1, FAAH, NAAA and MGLL genes are associated with anorexia nervosa (AN)...
  4. pmc Chicken ovalbumin upstream promoter transcription factor II regulates uncoupling protein 3 gene transcription in Phodopus sungorus
    Tobias Fromme
    Department of Animal Physiology, Faculty of Biology, Philipps University, D 35043 Marburg, Germany
    BMC Mol Biol 8:1. 2007
    ..We therefore investigated whether Coup-TFII is a further player in the transcriptional control of the Ucp3 gene in rodents...
  5. pmc The transcript catalogue of the short-lived fish Nothobranchius furzeri provides insights into age-dependent changes of mRNA levels
    Andreas Petzold
    Genome Analysis, Leibniz Institute for Age Research Fritz Lipmann Institute, Beutenbergstr 11, Jena 07745, Germany
    BMC Genomics 14:185. 2013
    ..To substantiate its role as an alternative vertebrate ageing model, a transcript catalogue is needed, which can serve e.g. as basis for identifying ageing-related genes...
  6. doi request reprint Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri
    Nils Hartmann
    Department of Molecular Genetics, Leibniz Institute for Age Research Fritz Lipmann Institute FLI, Beutenbergstrasse 11, Jena, Germany
    Aging Cell 10:824-31. 2011
    ..These findings suggest that despite the short lifespan, aging in N. furzeri is associated with a decline in mtDNA copy number, the downregulation of mtDNA-associated genes and an impairment of mitochondrial function...
  7. pmc Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1
    Stefanie Stepanow
    Genome Analysis, Leibniz Institute for Age Research, Jena, Germany
    PLoS ONE 6:e17711. 2011
    ..In addition, 15 CpGs in close vicinity of these SNPs constitute a weak CpG island. Here, we studied whether DNA methylation in this sequence context may contribute to population- and age-specific effects of MCHR1 alleles in obesity...
  8. ncbi request reprint Method for preparing single-stranded DNA templates for Pyrosequencing using vector ligation and universal biotinylated primers
    Marco Groth
    Genome Analysis, Leibniz Institute for Age Research Fritz Lipmann Institute, 07745 Jena, Germany
    Anal Biochem 356:194-201. 2006
    ..As a proof of principle, we used the method for genotyping two single-nucleotide polymorphisms in the human genes CARD15 and A2M and for characterization of four multisite variations in the human DEFB104 gene...
  9. doi request reprint Absence of replicative senescence in cultured cells from the short-lived killifish Nothobranchius furzeri
    Michael Graf
    Molecular Genetics, Leibniz Institute for Age Research, Fritz Lipmann Institute, Beutenbergstr 11, 07745 Jena, Germany
    Exp Gerontol 48:17-28. 2013
    ..Hence, we propose that differences in maximum life span of different N. furzeri strains is not reflected by differences in proliferation speed or replicative potential of the respective cultured cells...
  10. pmc Parallel evolution of senescence in annual fishes in response to extrinsic mortality
    Eva Terzibasi Tozzini
    Fritz Lipmann Institute for Age Research, Leibniz Institute, Jena, Germany
    BMC Evol Biol 13:77. 2013
    ..We use 10 Nothobranchius populations from seasonal pools that differ in their duration to test how this parameter affects longevity and aging in two independent clades of these annual fishes...
  11. pmc The age related markers lipofuscin and apoptosis show different genetic architecture by QTL mapping in short-lived Nothobranchius fish
    Enoch Ng'oma
    Biology of Ageing, Leibniz Institute for Age Research Fritz Lipmann Institute, 07745 Jena, Germany
    Aging (Albany NY) 6:468-80. 2014
    ..001), showing additive and dominance effects, and two interacting loci. Our results show that lipofuscin and apoptosis are markers of different age-dependent biological processes controlled by different genetic mechanisms...
  12. pmc Mapping of quantitative trait loci controlling lifespan in the short-lived fish Nothobranchius furzeri--a new vertebrate model for age research
    Jeanette Kirschner
    Genome Analysis, Leibniz Institute for Age Research Fritz Lipmann Institute, Jena, Germany
    Aging Cell 11:252-61. 2012
    ..Our work provides first results on the way to identify loci controlling lifespan in N. furzeri and illustrates the potential of this vertebrate species as a genetic model for age research...
  13. doi request reprint Telomeres shorten while Tert expression increases during ageing of the short-lived fish Nothobranchius furzeri
    Nils Hartmann
    Leibniz Institute for Age Research Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany
    Mech Ageing Dev 130:290-6. 2009
    ..We further conclude that the extremely short lifespan of the GRZ strain is not caused by diminished telomerase activity or accelerated telomere shortening...
  14. pmc Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence
    Stefan Taudien
    Genomanalyse, Institut fur Molekulare Biotechnologie, Jena, Germany
    BMC Genomics 5:92. 2004
    ..1. This DEF locus, however, represents one of the regions in the euchromatic part of the final human genome sequence which contains segmental duplications, and recalcitrant gaps indicating high structural dynamics...