Frank Koster

Summary

Country: Germany

Publications

  1. doi request reprint Triple-negative breast cancers express receptors for growth hormone-releasing hormone (GHRH) and respond to GHRH antagonists with growth inhibition
    Frank Koster
    Department of Gynecology and Obstetrics, University of Lubeck, Lubeck, Germany
    Breast Cancer Res Treat 116:273-9. 2009
  2. ncbi request reprint Cell-specific enhancement of liposomal transfection by steroids in steroid receptor expressing cells
    Frank Koster
    Department of Obstetrics and Gynecology, University of Lubeck, D 23538 Lubeck, Germany
    Int J Mol Med 18:1201-5. 2006
  3. ncbi request reprint Vitamin D inhibits ovarian cancer cell line proliferation in combination with celecoxib and suppresses cyclooxygenase-2 expression
    Marc Thill
    Department of Gynecology and Obstetrics, Agaplesion Markus Hospital, Frankfurt am Main, Germany
    Anticancer Res 35:1197-203. 2015
  4. ncbi request reprint Vitamin D, calcidiol and calcitriol regulate vitamin D metabolizing enzymes in cervical and ovarian cancer cells
    Martin Kloss
    Department of Obstetrics and Gynecology, University of Lubeck, D 23538 Lubeck, Germany
    Anticancer Res 30:4429-34. 2010
  5. ncbi request reprint Disrupting Y-Box-Binding Protein 1 Function Using OSU-03012 Prevents Endometriosis Progression in In Vitro and In Vivo Models
    Cássia G T Silveira
    Department of Obstetrics and Gynecology, University of Lubeck, Lubeck, Germany
    Reprod Sci . 2016
  6. ncbi request reprint Combined treatment of breast cancer cell lines with vitamin D and COX-2 inhibitors
    Marc Thill
    Department of Gynecology and Obstetrics, Agaplesion Markus Hospital, Frankfurt am Main, Germany
    Anticancer Res 35:1189-95. 2015
  7. doi request reprint Targeting triple-negative breast cancer through the somatostatin receptor with the new cytotoxic somatostatin analogue AN-162 [AEZS-124]
    Stephan Seitz
    Department of Gynecology and Obstetrics, University Medical Center Regensburg, Regensburg, Germany
    Anticancer Drugs 24:150-7. 2013
  8. pmc Expression of cyclooxygenase-2 in cervical cancer is associated with lymphovascular invasion
    Friederike Hoellen
    Department of Gynecology and Obstetrics, University of Lübeck and University Hospital Schleswig Holstein, Lübeck Campus, Lübeck D 23538, Germany
    Oncol Lett 12:2351-2356. 2016
  9. ncbi request reprint Subtypes of Triple-negative Breast Cancer Cell Lines React Differently to Eribulin Mesylate
    Karen Bräutigam
    Department of Gynecology and Obstetrics, University Medical Center Schleswig Holstein, Lubeck, Germany
    Anticancer Res 36:2759-66. 2016
  10. pmc L1 cell adhesion molecule as a potential therapeutic target in murine models of endometriosis using a monoclonal antibody approach
    Cássia G T Silveira
    Department of Gynecology and Obstetrics, University of Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    PLoS ONE 8:e82512. 2013

Collaborators

Detail Information

Publications12

  1. doi request reprint Triple-negative breast cancers express receptors for growth hormone-releasing hormone (GHRH) and respond to GHRH antagonists with growth inhibition
    Frank Koster
    Department of Gynecology and Obstetrics, University of Lubeck, Lubeck, Germany
    Breast Cancer Res Treat 116:273-9. 2009
    ..Our in vitro studies demonstrate that targeting the GHRH receptor may be a therapeutic option which should be evaluated in studies in vivo...
  2. ncbi request reprint Cell-specific enhancement of liposomal transfection by steroids in steroid receptor expressing cells
    Frank Koster
    Department of Obstetrics and Gynecology, University of Lubeck, D 23538 Lubeck, Germany
    Int J Mol Med 18:1201-5. 2006
    ..Liposomal transfection in combination with steroids might be useful for a cell-specific enhancement of gene transfer for example in gynecological malignoma where subgroups are expressing high levels of steroid receptors...
  3. ncbi request reprint Vitamin D inhibits ovarian cancer cell line proliferation in combination with celecoxib and suppresses cyclooxygenase-2 expression
    Marc Thill
    Department of Gynecology and Obstetrics, Agaplesion Markus Hospital, Frankfurt am Main, Germany
    Anticancer Res 35:1197-203. 2015
    ..Prostaglandin-(PG)E2 is a tumor-promoting tissue hormone anabolized by cyclooxygenase-2 (COX-2). Recently, a link between the PG and vitamin D metabolism was reported...
  4. ncbi request reprint Vitamin D, calcidiol and calcitriol regulate vitamin D metabolizing enzymes in cervical and ovarian cancer cells
    Martin Kloss
    Department of Obstetrics and Gynecology, University of Lubeck, D 23538 Lubeck, Germany
    Anticancer Res 30:4429-34. 2010
    ..The aim of this study was to obtain further information about the regulation of the aforementioned enzymes by vitamin D, calcidiol and calcitriol in cervical and ovarian cancer...
  5. ncbi request reprint Disrupting Y-Box-Binding Protein 1 Function Using OSU-03012 Prevents Endometriosis Progression in In Vitro and In Vivo Models
    Cássia G T Silveira
    Department of Obstetrics and Gynecology, University of Lubeck, Lubeck, Germany
    Reprod Sci . 2016
    ..0346). In conclusion, targeting YB-1 via OSU-03012 showed a potent antiproliferative effect on endometriotic epithelial cells in vitro and in a mouse model of disease...
  6. ncbi request reprint Combined treatment of breast cancer cell lines with vitamin D and COX-2 inhibitors
    Marc Thill
    Department of Gynecology and Obstetrics, Agaplesion Markus Hospital, Frankfurt am Main, Germany
    Anticancer Res 35:1189-95. 2015
    ..Prostaglandin E2 (PGE2) is a proliferation and inflammation activating agent. The production of PGE2 is dependent on the activity of cyclooxygenase-2 (COX-2). A link between vitamin D and PGE2 metabolism was recently shown...
  7. doi request reprint Targeting triple-negative breast cancer through the somatostatin receptor with the new cytotoxic somatostatin analogue AN-162 [AEZS-124]
    Stephan Seitz
    Department of Gynecology and Obstetrics, University Medical Center Regensburg, Regensburg, Germany
    Anticancer Drugs 24:150-7. 2013
    ..This investigation provides information on the mechanism of action and efficacy of this new targeted cytotoxic sst analogue and identifies in this relation the sstr as a favorable therapeutic target in TNBC...
  8. pmc Expression of cyclooxygenase-2 in cervical cancer is associated with lymphovascular invasion
    Friederike Hoellen
    Department of Gynecology and Obstetrics, University of Lübeck and University Hospital Schleswig Holstein, Lübeck Campus, Lübeck D 23538, Germany
    Oncol Lett 12:2351-2356. 2016
    ..Further studies including larger patient collectives are required in order to perform analyses of clinical subgroups and patient survival...
  9. ncbi request reprint Subtypes of Triple-negative Breast Cancer Cell Lines React Differently to Eribulin Mesylate
    Karen Bräutigam
    Department of Gynecology and Obstetrics, University Medical Center Schleswig Holstein, Lubeck, Germany
    Anticancer Res 36:2759-66. 2016
    ..The goal of this analysis was to compare TNBC vs. non-TNBC cell lines and those of distinct TNBC subtypes with regard to sensitivity to eribulin in vitro...
  10. pmc L1 cell adhesion molecule as a potential therapeutic target in murine models of endometriosis using a monoclonal antibody approach
    Cássia G T Silveira
    Department of Gynecology and Obstetrics, University of Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    PLoS ONE 8:e82512. 2013
    ....
  11. ncbi request reprint Immunohistochemistry of DNA mismatch repair enzyme MSH2 is not correlated with prognostic data from endometrial carcinomas
    Andreas Schröer
    Department of Gynecology and Obstetrics, University of Lubeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    Anticancer Res 29:4833-7. 2009
    ..Insufficient MMR activity or expression levels could be prognostic markers of the disease...
  12. ncbi request reprint Additive effect of steroids and cholesterol on the liposomal transfection of the breast cancer cell line T-47D
    Frank Koster
    Department of Obstetrics and Gynecology, University of Lubeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    Int J Mol Med 14:769-72. 2004
    ....