Lars Komorowski

Summary

Country: Germany

Publications

  1. doi request reprint Autoantibodies against exocrine pancreas in Crohn's disease are directed against two antigens: the glycoproteins CUZD1 and GP2
    Lars Komorowski
    Institute of Experimental Immunology, EUROIMMUN AG, Luebeck, Germany Electronic address
    J Crohns Colitis 7:780-90. 2013
  2. pmc Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients
    Katharina Hanke
    Department of Rheumatology and Clinical Immunology, Charite Universitatsmedizin, Humboldt University Berlin, Chariteplatz 1, Berlin 10117, Germany
    Arthritis Res Ther 11:R22. 2009
  3. doi request reprint Development of a recombinant cell-based indirect immunofluorescence assay (RC-IFA) for the determination of autoantibodies against "rings and rods"-associated inosine-5'-monophosphate dehydrogenase 2 in viral hepatitis C
    Christian Probst
    Institute of Experimental Immunology, EUROIMMUN AG, Lubeck, Germany
    Clin Chim Acta 418:91-6. 2013
  4. doi request reprint Differential diagnosis of membranous nephropathy with autoantibodies to phospholipase A2 receptor 1
    Wolfgang Schlumberger
    Institute for Experimental Immunology, Euroimmun, Seekamp 31, 23560 Lübeck, Germany Electronic address
    Autoimmun Rev 13:108-13. 2014
  5. doi request reprint Immunoadsorber for specific apheresis of autoantibodies in the treatment of bullous pemphigoid
    Michael Mersmann
    Institute of Experimental Immunology, EUROIMMUN AG, Seekamp 31, 23560, Lubeck, Germany
    Arch Dermatol Res 308:31-8. 2016
  6. pmc Development of a recombinant cell-based indirect immunofluorescence assay for the determination of autoantibodies against soluble liver antigen in autoimmune hepatitis
    Christiane Radzimski
    Institute of Experimental Immunology, EUROIMMUN AG, Seekamp 31, 23560 Lübeck, Germany
    Clin Dev Immunol 2013:572815. 2013
  7. doi request reprint Development of a standardized ELISA for the determination of autoantibodies against human M-type phospholipase A2 receptor in primary membranous nephropathy
    Cornelia Dähnrich
    EUROIMMUN AG, Lubeck, Germany
    Clin Chim Acta 421:213-8. 2013
  8. doi request reprint New ELISA for detecting primary biliary cirrhosis-specific antimitochondrial antibodies
    Cornelia Dähnrich
    EUROIMMUN AG, Lubeck, Germany
    Clin Chem 55:978-85. 2009
  9. doi request reprint Specific immunoadsorption of pathogenic autoantibodies in pemphigus requires the entire ectodomains of desmogleins
    Jana Langenhan
    Institute of Experimental Immunology, EUROIMMUN AG, Lubeck, Germany
    Exp Dermatol 23:253-9. 2014
  10. pmc Serological diagnosis of autoimmune bullous skin diseases: prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy
    Nina van Beek
    Department of Dermatology, University of Luebeck, Luebeck, Germany
    Orphanet J Rare Dis 7:49. 2012

Collaborators

Detail Information

Publications13

  1. doi request reprint Autoantibodies against exocrine pancreas in Crohn's disease are directed against two antigens: the glycoproteins CUZD1 and GP2
    Lars Komorowski
    Institute of Experimental Immunology, EUROIMMUN AG, Luebeck, Germany Electronic address
    J Crohns Colitis 7:780-90. 2013
    ....
  2. pmc Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients
    Katharina Hanke
    Department of Rheumatology and Clinical Immunology, Charite Universitatsmedizin, Humboldt University Berlin, Chariteplatz 1, Berlin 10117, Germany
    Arthritis Res Ther 11:R22. 2009
    ..Furthermore, it remains speculative whether commercially available test systems detecting only anti-PM/Scl-100 antibodies are sufficient in SSc patients...
  3. doi request reprint Development of a recombinant cell-based indirect immunofluorescence assay (RC-IFA) for the determination of autoantibodies against "rings and rods"-associated inosine-5'-monophosphate dehydrogenase 2 in viral hepatitis C
    Christian Probst
    Institute of Experimental Immunology, EUROIMMUN AG, Lubeck, Germany
    Clin Chim Acta 418:91-6. 2013
    ..We wanted to confirm the identification and setup a robust system for autoantibody testing in routine laboratories...
  4. doi request reprint Differential diagnosis of membranous nephropathy with autoantibodies to phospholipase A2 receptor 1
    Wolfgang Schlumberger
    Institute for Experimental Immunology, Euroimmun, Seekamp 31, 23560 Lübeck, Germany Electronic address
    Autoimmun Rev 13:108-13. 2014
    ..Further research into pathogenic mechanisms and other disease markers can pave the way for improved patient care. ..
  5. doi request reprint Immunoadsorber for specific apheresis of autoantibodies in the treatment of bullous pemphigoid
    Michael Mersmann
    Institute of Experimental Immunology, EUROIMMUN AG, Seekamp 31, 23560, Lubeck, Germany
    Arch Dermatol Res 308:31-8. 2016
    ..The NC16A-trimer adsorber was regenerable and autoclavable. It has the potential to be used for specific immunoadsorption to treat severe and refractory BP and other pemphigoid diseases associated with BP180 NC16A reactivity. ..
  6. pmc Development of a recombinant cell-based indirect immunofluorescence assay for the determination of autoantibodies against soluble liver antigen in autoimmune hepatitis
    Christiane Radzimski
    Institute of Experimental Immunology, EUROIMMUN AG, Seekamp 31, 23560 Lübeck, Germany
    Clin Dev Immunol 2013:572815. 2013
    ..In concert with cryosections of primate liver, rat kidney, rat liver, rat stomach, and HEp-2 cells, they enable the parallel determination of all autoantibodies associated with autoimmune liver diseases...
  7. doi request reprint Development of a standardized ELISA for the determination of autoantibodies against human M-type phospholipase A2 receptor in primary membranous nephropathy
    Cornelia Dähnrich
    EUROIMMUN AG, Lubeck, Germany
    Clin Chim Acta 421:213-8. 2013
    ..So far, a recombinant cell-based indirect immunofluorescence assay (RC-IFA) using recombinant PLA2R1 as a substrate has been widely available but lacks a finely graduated assessment of antibody concentrations...
  8. doi request reprint New ELISA for detecting primary biliary cirrhosis-specific antimitochondrial antibodies
    Cornelia Dähnrich
    EUROIMMUN AG, Lubeck, Germany
    Clin Chem 55:978-85. 2009
    ..More recent assays have employed a hybrid containing the 3 E2-subunits (MIT3). Some PBC sera react with one or the other preparation, suggesting the presence of nonoverlapping epitopes...
  9. doi request reprint Specific immunoadsorption of pathogenic autoantibodies in pemphigus requires the entire ectodomains of desmogleins
    Jana Langenhan
    Institute of Experimental Immunology, EUROIMMUN AG, Lubeck, Germany
    Exp Dermatol 23:253-9. 2014
    ..Therefore, the complete and correctly folded ectodomains of both desmogleins are required for therapeutic immunoadsorption. ..
  10. pmc Serological diagnosis of autoimmune bullous skin diseases: prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy
    Nina van Beek
    Department of Dermatology, University of Luebeck, Luebeck, Germany
    Orphanet J Rare Dis 7:49. 2012
    ..BIOCHIP mosaics consisting of different antigen substrates allow polyvalent immunofluorescence (IF) tests and provide antibody profiles in a single incubation...
  11. doi request reprint N-terminal disulfide-bridging of Borrelia outer surface protein C increases its diagnostic and vaccine potentials
    Christian Probst
    Institute of Experimental Immunology, EUROIMMUN AG, Seekamp 31, D 23560 Lübeck, Germany
    Ticks Tick Borne Dis 3:1-7. 2012
    ..We conclude that the disulfide-bridging of 2 OspC molecules via their N termini forms a complex that is more suitable for the determination of IgM-OspC and is a promising candidate for a monovalent vaccine...
  12. doi request reprint DNA-bound lactoferrin is the major target for antineutrophil perinuclear cytoplasmic antibodies in ulcerative colitis
    Bianca Teegen
    Institute of Experimental Immunology, EUROIMMUN AG, Luebeck, Germany
    Ann N Y Acad Sci 1173:161-5. 2009
    ..Antigen-stripped and lactoferrin-reconstituted granulocytes can be used in IIF to diagnose antilactoferrin antibodies in UC more reliably than with existing ELISA systems...
  13. doi request reprint Sensitive and specific assays for routine serological diagnosis of epidermolysis bullosa acquisita
    Lars Komorowski
    Institute of Experimental Immunology, EUROIMMUN AG, Luebeck, Germany
    J Am Acad Dermatol 68:e89-95. 2013
    ..Epidermolysis bullosa acquisita (EBA) is a severe autoimmune subepidermal blistering disease characterized by autoantibodies against the N-terminal collagenous domain (NC1) of type VII collagen (Col VII)...