Jaroslav Pelisek

Summary

Affiliation: Klinikum rechts der Isar
Country: Germany

Publications

  1. doi request reprint Expression and cellular localization of metalloproteases ADAMs in high graded carotid artery lesions
    Jaroslav Pelisek
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich, Germany
    Scand J Clin Lab Invest 72:648-56. 2012
  2. ncbi request reprint Neovascularization and angiogenic factors in advanced human carotid artery stenosis
    Jaroslav Pelisek
    Clinic of Vascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Ismaninger Str 22 D 81675 Munich, Germany
    Circ J 76:1274-82. 2012
  3. doi request reprint Inflammatory infiltrates and neovessels are relevant sources of MMPs in abdominal aortic aneurysm wall
    Christian Reeps
    Department of Vascular Surgery, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany
    Pathobiology 76:243-52. 2009
  4. pmc Differentiation of human CD14+ monocytes: an experimental investigation of the optimal culture medium and evidence of a lack of differentiation along the endothelial line
    Wajima Safi
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitat Munchen, Munchen, Germany
    Exp Mol Med 48:e227. 2016
  5. doi request reprint Reporter gene PET for monitoring survival of transplanted endothelial progenitor cells in the rat heart after pretreatment with VEGF and atorvastatin
    Takahiro Higuchi
    Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Nucl Med 50:1881-6. 2009
  6. doi request reprint Characterization of carotid artery plaques with USPIO-enhanced MRI: assessment of inflammation and vascularity as in vivo imaging biomarkers for plaque vulnerability
    Stephan Metz
    Department of Diagnostic Radiology, Technische Universitaet Muenchen, Ismaninger Str 22, 81675, Munich, Germany
    Int J Cardiovasc Imaging 27:901-12. 2011
  7. doi request reprint Multiple biological predictors for vulnerable carotid lesions
    Jaroslav Pelisek
    Department of Vascular Surgery, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Strasse 22, Munich, Germany
    Cerebrovasc Dis 28:601-10. 2009
  8. doi request reprint Histone acetylation and methylation significantly change with severity of atherosclerosis in human carotid plaques
    Anna Greißel
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Germany
    Cardiovasc Pathol 25:79-86. 2016
  9. doi request reprint Meta-analysis shows similar risk of thrombosis after drug-eluting stent, bare-metal stent, or angioplasty
    Alexandra Theresia Fuchs
    Department of Paediatric Cardiology, University Hospital Grosshadern, Ludwig Maximilian University, Munich, Germany
    Endothelium 15:93-100. 2008
  10. pmc Association between carotid diameter and the advanced glycation end product N-epsilon-carboxymethyllysine (CML)
    Marcus Baumann
    Department of Nephrology, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Cardiovasc Diabetol 8:45. 2009

Collaborators

Detail Information

Publications32

  1. doi request reprint Expression and cellular localization of metalloproteases ADAMs in high graded carotid artery lesions
    Jaroslav Pelisek
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich, Germany
    Scand J Clin Lab Invest 72:648-56. 2012
    ..In conclusion, the ADAM family of proteases seems to play an important role in the maintenance of proper vessel physiology and some ADAMs such as ADAM10 and ADAM12 might also contribute to the progression of atherosclerosis...
  2. ncbi request reprint Neovascularization and angiogenic factors in advanced human carotid artery stenosis
    Jaroslav Pelisek
    Clinic of Vascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Ismaninger Str 22 D 81675 Munich, Germany
    Circ J 76:1274-82. 2012
    ..The aim of this study was to analyze the possible relationships among neovascularization, relevant angiogenic factors, and plaque vulnerability in patients with advanced carotid artery stenosis...
  3. doi request reprint Inflammatory infiltrates and neovessels are relevant sources of MMPs in abdominal aortic aneurysm wall
    Christian Reeps
    Department of Vascular Surgery, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany
    Pathobiology 76:243-52. 2009
    ..So far, MMP expression within AAA wall in association with infiltrates and neovascularization has not yet been studied...
  4. pmc Differentiation of human CD14+ monocytes: an experimental investigation of the optimal culture medium and evidence of a lack of differentiation along the endothelial line
    Wajima Safi
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitat Munchen, Munchen, Germany
    Exp Mol Med 48:e227. 2016
    ..There is no further benefit in culturing monocytes longer than 7 days. The cultivation of monocytes in the tested media leads preferentially to differentiation into macrophages. Differentiation into endothelial cells did not take place. ..
  5. doi request reprint Reporter gene PET for monitoring survival of transplanted endothelial progenitor cells in the rat heart after pretreatment with VEGF and atorvastatin
    Takahiro Higuchi
    Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Nucl Med 50:1881-6. 2009
    ..We investigated whether reporter gene PET can be used to detect the effects of atorvastatin and VEGF on survival of EPCs after transplantation in the rat heart...
  6. doi request reprint Characterization of carotid artery plaques with USPIO-enhanced MRI: assessment of inflammation and vascularity as in vivo imaging biomarkers for plaque vulnerability
    Stephan Metz
    Department of Diagnostic Radiology, Technische Universitaet Muenchen, Ismaninger Str 22, 81675, Munich, Germany
    Int J Cardiovasc Imaging 27:901-12. 2011
    ..Diagnostic MRA of the supra-aortal vessels can be imaged additionally with a single administration of SHU 555 C...
  7. doi request reprint Multiple biological predictors for vulnerable carotid lesions
    Jaroslav Pelisek
    Department of Vascular Surgery, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Strasse 22, Munich, Germany
    Cerebrovasc Dis 28:601-10. 2009
    ....
  8. doi request reprint Histone acetylation and methylation significantly change with severity of atherosclerosis in human carotid plaques
    Anna Greißel
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Germany
    Cardiovasc Pathol 25:79-86. 2016
    ..The aim of the study was to analyze histone acetylation, methylation, and the expression of their corresponding transferases in atherosclerotic plaques of patients with carotid artery stenosis...
  9. doi request reprint Meta-analysis shows similar risk of thrombosis after drug-eluting stent, bare-metal stent, or angioplasty
    Alexandra Theresia Fuchs
    Department of Paediatric Cardiology, University Hospital Grosshadern, Ludwig Maximilian University, Munich, Germany
    Endothelium 15:93-100. 2008
    ..In conclusion, the use of DES was not observed to have a significant effect on stent thrombosis events, compared with the implantation of BMS or balloon angioplasty...
  10. pmc Association between carotid diameter and the advanced glycation end product N-epsilon-carboxymethyllysine (CML)
    Marcus Baumann
    Department of Nephrology, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Cardiovasc Diabetol 8:45. 2009
    ..AGEs are associated with hypertension and arterial stiffness potentially by qualitative changes of elastic fibers. We investigated whether CML affects carotid and aortic properties in normoglycemic subjects...
  11. doi request reprint Impact of sex and age on carotid plaque instability in asymptomatic patients-results from the Munich Vascular Biobank
    Carina Wendorff
    1 Department of Vascular and Endovascular Surgery, University Hospital Rechts der Isar, Munich, Germany
    Vasa 45:411-6. 2016
    ..The aim of this study was therefore to analyze the impact of sex and age on carotid plaque instability in asymptomatic patients undergoing CEA...
  12. pmc Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms
    Fabian Lohoefer
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich, Germany
    Exp Mol Med 46:e95. 2014
    ..All cysteine/aspartic proteases analyzed in our study were detected in the AAA and healthy aorta. The highest expression was found in macrophages and SMCs. Consequently, cysteine/aspartic proteases might play a substantial role in AAA. ..
  13. pmc Histopathological analysis of cellular localization of cathepsins in abdominal aortic aneurysm wall
    Fabian Lohoefer
    Clinic for Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Muenchen, Germany
    Int J Exp Pathol 93:252-8. 2012
    ..Our data are broadly consistent with a role for cathepsins in AAA; and demonstrate expression of cathepsins D, B and S in phagocytic cells in the inflammatory infiltrate; and also may reveal a role for cathepsin B in lymphocytes...
  14. ncbi request reprint Expression of a metalloproteinase family of ADAMTS in human vulnerable carotid lesions
    Jaroslav Pelisek
    aDepartment of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich bKantonsspital Baselland, Orthopaedics und Traumatology, CH 4410 Liestal cDepartment of Surgery, Munich Transplant Centre, Klinikum rechts der Isar der Technischen Universitaet Muenchen dDZHK German Centre for Cardiovascular Research, partner site Munich Heart Alliance, Munich, Germany
    J Cardiovasc Med (Hagerstown) 18:10-18. 2017
    ..Their expression pattern in carotid plaques is as-yet unknown. The aim of the study was therefore the analysis of expression of ADAMTS1, 4, 5, and 13 and their inhibitors TIMP-1 and TIMP-3 in stable and unstable carotid plaques...
  15. doi request reprint Carotid Plaque Morphology Is Significantly Associated With Sex, Age, and History of Neurological Symptoms
    Carina Wendorff
    From the Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany C W, H W, J P, P T, A Zimmermann, A Zernecke, A K, H H E DZHK Deutschez Zentrum für Herz Kreislauf Forschung, partner site Munich Heart Alliance, Munich, Germany J P, H H E and Institute of Clinical Biochemistry and Pathobiochemistry, University Hospital Wurzburg, Wurzburg, Germany A Zernecke
    Stroke 46:3213-9. 2015
    ..The purpose of this study was to analyze the association between morphological characteristics of human carotid plaques and patient's sex, age, and history of neurological symptoms...
  16. doi request reprint C-type natriuretic peptide slows down wound healing but promotes angiogenesis in SKH1-hr hairless mice
    Andreas Kuehnl
    Clinic for Vascular an Endovascular Surgery, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Int Wound J 10:425-30. 2013
    ..A possible explanation is the dual effect of CNP, inhibiting growth of fibromyoblasts but stimulating growth of endothelial cells. Thus, CNP may serve as a therapeutic approach to diseases caused by hyperfibrosis. ..
  17. ncbi request reprint Age-associated changes in human carotid atherosclerotic plaques
    Jaroslav Pelisek
    a Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich, Germany
    Ann Med 48:541-551. 2016
    ..Based on the current data, the age-associated plaque morphology seems to transform toward vulnerable plaques. However, the changes do not seem to be as disastrous as expected...
  18. doi request reprint A short time interval between the neurologic index event and carotid endarterectomy is not a risk factor for carotid surgery
    Pavlos Tsantilas
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
    J Vasc Surg 65:12-20.e1. 2017
    ..Therefore, the aim of this single-center study was to determine the effect of the time interval between the neurologic index event and CEA on the periprocedural complication rate at our institution...
  19. doi request reprint Endothelial differentiation of adipose-derived mesenchymal stem cells is improved by epigenetic modifying drug BIX-01294
    Mihaela Culmes
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University Munich, Germany
    Eur J Cell Biol 92:70-9. 2013
    ..Hence, BIX-01294 might serve as a simple tool to increase the differentiation potential of AdMSCs...
  20. doi request reprint Pathophysiological mechanisms of carotid plaque vulnerability: impact on ischemic stroke
    Jaroslav Pelisek
    Clinic for Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Ismaninger Str 22, 81675, Munich, Germany
    Arch Immunol Ther Exp (Warsz) 60:431-42. 2012
    ..The identification and careful integration of all relevant factors will be required for the development of future diagnostic and therapeutic strategies...
  21. doi request reprint Expression of a disintegrin and metalloprotease in human abdominal aortic aneurysms
    Christina Lipp
    Clinic of Vascular Surgery, Institute of Pathology, Department of Nephrology, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany
    J Vasc Res 49:198-206. 2012
    ..The aim of this study was to make a detailed analysis of the expression of ADAMs 8, 9, 10, 12, 15 and 17, and their tissue inhibitors of metalloprotease (TIMP)-1 and TIMP-3 in patients with AAA...
  22. doi request reprint Combined reporter gene PET and iron oxide MRI for monitoring survival and localization of transplanted cells in the rat heart
    Takahiro Higuchi
    Nuklearmedizinische Klinik und Poliklinik, Technische Universitat Munchen, Munich, Germany
    J Nucl Med 50:1088-94. 2009
    ..This study assessed the feasibility and usefulness of combined PET and MRI for monitoring cell engraftment and survival after cell transplantation...
  23. pmc MRI plaque imaging detects carotid plaques with a high risk for future cerebrovascular events in asymptomatic patients
    Lorena Esposito-Bauer
    Department of Neurology, Technische Universitat Munchen, Munich, Germany
    PLoS ONE 8:e67927. 2013
    ..Within these lesion types, lesion types IV-V and VI are regarded as rupture-prone plaques, whereas the other lesion types represent stable ones...
  24. doi request reprint Early venous manifestation of Ehlers-Danlos syndrome Type IV through a novel mutation in COL3A1
    Heiko Wendorff
    Clinic of Vascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Germany
    Cardiovasc Pathol 22:488-92. 2013
    ..Our findings imply that molecular genetic analysis should be considered in patients with unusual clinical presentation and that conservative therapy should be applied until a suspected clinical diagnosis has been secured. ..
  25. pmc Comparative measurement of CNP and NT-proCNP in human blood samples: a methodological evaluation
    Andreas Kuehnl
    Clinic for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Negat Results Biomed 12:7. 2013
    ..In order to identify potential methodological bias, this study should also validate the stability of CNP and NT-proCNP in full blood samples stored at room temperature...
  26. pmc MRI plaque imaging reveals high-risk carotid plaques especially in diabetic patients irrespective of the degree of stenosis
    L Esposito
    Department of Neurology, Klinikum rechts der Isar, Technische Universitat, Munich, Germany
    BMC Med Imaging 10:27. 2010
    ..This study investigates whether MRI-plaque imaging can reveal differences in carotid plaque features of diabetic patients compared to nondiabetics...
  27. doi request reprint Increased 18F-fluorodeoxyglucose uptake in abdominal aortic aneurysms in positron emission/computed tomography is associated with inflammation, aortic wall instability, and acute symptoms
    Christian Reeps
    Department of Vascular Surgery, University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany
    J Vasc Surg 48:417-23; discussion 424. 2008
    ..The aim of the study was to analyze the histopathologic changes in AAA wall correlated with increased FDG uptake for further implications on aortic wall stability and AAA rupture risk...
  28. doi request reprint Ex vivo characterization of carotid plaques by intravascular ultrasonography and virtual histology: concordance with real plaque pathomorphology
    Martina Fuchs
    Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich, Germany
    J Cardiovasc Surg (Torino) 58:55-64. 2017
    ..The purpose of this study was to evaluate the accuracy of carotid plaque characterisation by virtual histology using intravascular ultrasonography (VH-IVUS) by comparing the results with real morphology...
  29. doi request reprint Biomechanics and gene expression in abdominal aortic aneurysm
    Christian Reeps
    Department of Vascular and Endovascular Surgery, Technische Universitat, Munich, Germany Electronic address
    J Vasc Surg 60:1640-7.e1-2. 2014
    ....
  30. doi request reprint Inhibition of restenosis formation without compromising reendothelialization as a potential solution to thrombosis following angioplasty?
    Alexandra Theresia Fuchs
    Department of Paediatric Cardiology, University Hospital Grosshadern, Ludwig Maximilian University, Munich, Germany
    Endothelium 15:85-92. 2008
    ..Therefore, use of the CNP gene may offer a solution to suppress restenosis formation while preventing subacute or late thrombosis...
  31. doi request reprint Thrombus Histology Suggests Cardioembolic Cause in Cryptogenic Stroke
    Tobias Boeckh-Behrens
    From the Department of Neuroradiology T B B, J F K, C Z, Department of Vascular and Endovascular Surgery J P, and Department of Neurology L S, K N, D K, H P, University Hospital Rechts der Isar, Technical University Munich, Munich, Germany Department of Pathology, German Research Centre for Environmental Health, Munich, Germany F N and Department of Statistics, Ludwig Maximilians University Munich, Munich, Germany F S
    Stroke 47:1864-71. 2016
    ..This study examines the relationship between stroke causes and histological clot composition to identify specific patterns that might help to distinguish causes of cryptogenic stroke...
  32. ncbi request reprint Fibrinogen and high-sensitive C-reactive protein as serologic predictors for perioperative cerebral microembolic lesions after carotid endarterectomy
    Peter Heider
    Department of Vascular Surgery, Rechts der Isar Medical Center, Technical University of Munich, Munich, Germany
    J Vasc Surg 46:449-54. 2007
    ..This study should elucidate preoperative risk factors for perioperative microemboli that cause brain infarction...