Christopher Heeschen

Summary

Affiliation: Klinikum rechts der Isar
Country: Germany

Publications

  1. ncbi request reprint Biomarkers in acute coronary syndromes and their role in diabetic patients
    Christopher Heeschen
    Experimental Surgery, Department of Surgery, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Diab Vasc Dis Res 2:122-7. 2005
  2. doi request reprint Prostaglandin E positively modulates endothelial progenitor cell homeostasis: an advanced treatment modality for autologous cell therapy
    Tanja Herrler
    Department of Surgery, Experimental Medicine, Ludwig Maximilian University, Munich, Germany
    J Vasc Res 46:333-46. 2009
  3. ncbi request reprint Elevated placental growth factor levels are associated with adverse outcomes at four-year follow-up in patients with acute coronary syndromes
    Timo Lenderink
    Department of Cardiology, Atrium Medical Centre, Heerlen, The Netherlands
    J Am Coll Cardiol 47:307-11. 2006
  4. ncbi request reprint Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes
    Stephan Baldus
    University of Hamburg, Department of Cardiology, Martinistrasse 52, 20246 Hamburg, Germany
    Circulation 108:1440-5. 2003
  5. ncbi request reprint Serum level of the antiinflammatory cytokine interleukin-10 is an important prognostic determinant in patients with acute coronary syndromes
    Christopher Heeschen
    Department of Internal Medicine IV, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Circulation 107:2109-14. 2003
  6. ncbi request reprint Influence of sample type on soluble CD40 ligand assessment in patients with acute coronary syndromes
    Michael Weber
    Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim, Germany
    Thromb Res 120:811-4. 2007
  7. ncbi request reprint Prognostic significance of angiogenic growth factor serum levels in patients with acute coronary syndromes
    Christopher Heeschen
    Department of Internal Medicine IV, Molecular Cardiology, University of Frankfurt, Germany
    Circulation 107:524-30. 2003
  8. ncbi request reprint Withdrawal of statins in patients with acute coronary syndromes
    Christopher Heeschen
    Circulation 107:e27. 2003
  9. ncbi request reprint N-terminal pro-B-type natriuretic peptide levels for dynamic risk stratification of patients with acute coronary syndromes
    Christopher Heeschen
    J W Goethe University, Department of Cardiology, Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Circulation 110:3206-12. 2004
  10. ncbi request reprint Influence of sample type and storage conditions on soluble CD40 ligand assessment
    Michael Weber
    Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim, Germany
    Clin Chem 52:888-91. 2006

Collaborators

  • Reinhard Kopp
  • H White
  • Maarten L Simoons
  • C Hamm
  • Stephan Fichtlscherer
  • Eric Boersma
  • Timo Lenderink
  • T Munzel
  • Albrecht Elsasser
  • Michael Bohm
  • Michael Weber
  • Andreas M Zeiher
  • Carmen Urbich
  • Stefanie Dimmeler
  • Tanja Herrler
  • Birgitt Rabenau
  • Vesselin Mitrovic
  • Michael Stanisch
  • Dirk H Walter
  • Alexandra Aicher
  • Lothar Rossig
  • Britta U Goldmann
  • Stephan Baldus
  • Stephan Huber
  • Theresa M Schwarz
  • Simon F Leicht
  • Patrick C Hermann
  • Helge Mollmann
  • Holger M Nef
  • Albrecht Elsaesser
  • Thomas Reinheckel
  • Thomas Bruhl
  • Emmanouil Chavakis
  • Jörg Hoffmann
  • Peter Vajkoczy
  • Judith Haendeler
  • Wolf K Hofmann
  • Mohammad R Farhadi
  • Ulrich Rochwalsky
  • Christoph Peters
  • Ken ichiro Sasaki
  • Nasreddin D Abolmaali
  • Jörg Honold
  • Ralf Lehmann
  • Florian Seeger
  • Len A Pennacchio
  • Johannes Reinhold
  • Fernando Arenzana-Seisdesdos
  • Kurt Brinker
  • Jürgen Berger
  • Susanne Kolbe-Busch
  • Christoph Niederau
  • Ullrich Tebbe
  • Eckhard Kuhrt
  • Eberhard Spanuth
  • Norbert Katz
  • Claudia Wenserit
  • Heiko Gundmar Lestin
  • Lukas Langenbrink
  • Guido Matschuck
  • Thomas Meinertz
  • Jason P Eiserich

Detail Information

Publications21

  1. ncbi request reprint Biomarkers in acute coronary syndromes and their role in diabetic patients
    Christopher Heeschen
    Experimental Surgery, Department of Surgery, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Diab Vasc Dis Res 2:122-7. 2005
    ..Eventually, tailored medical and interventional treatment of diabetic patients should help to prevent these cardiac events in a cost-effective manner...
  2. doi request reprint Prostaglandin E positively modulates endothelial progenitor cell homeostasis: an advanced treatment modality for autologous cell therapy
    Tanja Herrler
    Department of Surgery, Experimental Medicine, Ludwig Maximilian University, Munich, Germany
    J Vasc Res 46:333-46. 2009
    ..To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their effects on EPC production, trafficking and function...
  3. ncbi request reprint Elevated placental growth factor levels are associated with adverse outcomes at four-year follow-up in patients with acute coronary syndromes
    Timo Lenderink
    Department of Cardiology, Atrium Medical Centre, Heerlen, The Netherlands
    J Am Coll Cardiol 47:307-11. 2006
    ..This study sought to evaluate the predictive value of baseline placental growth factor (PlGF) for long-term cardiovascular events in acute coronary syndromes (ACS)...
  4. ncbi request reprint Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes
    Stephan Baldus
    University of Hamburg, Department of Cardiology, Martinistrasse 52, 20246 Hamburg, Germany
    Circulation 108:1440-5. 2003
    ..However, whether MPO also provides prognostic information in patients with ACS remains unknown...
  5. ncbi request reprint Serum level of the antiinflammatory cytokine interleukin-10 is an important prognostic determinant in patients with acute coronary syndromes
    Christopher Heeschen
    Department of Internal Medicine IV, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Circulation 107:2109-14. 2003
    ..Therefore, we investigated the prognostic impact of key inflammatory players, namely the inflammatory marker C-reactive protein (CRP) and the antiinflammatory cytokine interleukin-10 (IL-10), in patients with acute coronary syndromes...
  6. ncbi request reprint Influence of sample type on soluble CD40 ligand assessment in patients with acute coronary syndromes
    Michael Weber
    Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim, Germany
    Thromb Res 120:811-4. 2007
    ..Thus, it was the aim of our prospective study to evaluate the impact of sampling techniques on sCD40L concentrations of patients with acute coronary syndromes compared to controls...
  7. ncbi request reprint Prognostic significance of angiogenic growth factor serum levels in patients with acute coronary syndromes
    Christopher Heeschen
    Department of Internal Medicine IV, Molecular Cardiology, University of Frankfurt, Germany
    Circulation 107:524-30. 2003
    ..However, it is unknown whether their serum levels are related to clinical outcome...
  8. ncbi request reprint Withdrawal of statins in patients with acute coronary syndromes
    Christopher Heeschen
    Circulation 107:e27. 2003
  9. ncbi request reprint N-terminal pro-B-type natriuretic peptide levels for dynamic risk stratification of patients with acute coronary syndromes
    Christopher Heeschen
    J W Goethe University, Department of Cardiology, Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Circulation 110:3206-12. 2004
    ....
  10. ncbi request reprint Influence of sample type and storage conditions on soluble CD40 ligand assessment
    Michael Weber
    Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim, Germany
    Clin Chem 52:888-91. 2006
    ..However, few data are available on preanalytic conditions that impact sCD40L values. Thus, the aim of our prospective study was to evaluate the impact of sampling techniques and storage conditions on sCD40L concentrations...
  11. ncbi request reprint Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease
    Dirk H Walter
    Molecular Cardiology, Department of Internal Medicine III, University of Frankfurt, Frankfurt, Germany
    Circ Res 97:1142-51. 2005
    ..Stimulating CXCR4 signaling might improve functional properties of EPC and may rescue impaired neovascularization capacity of EPC derived from patients with CAD...
  12. ncbi request reprint Cathepsin L is required for endothelial progenitor cell-induced neovascularization
    Carmen Urbich
    Molecular Cardiology, Department of Internal Medicine III, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Nat Med 11:206-13. 2005
    ..We concluded that CathL has a critical role in the integration of circulating EPC into ischemic tissue and is required for EPC-mediated neovascularization...
  13. ncbi request reprint Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis
    Christopher Heeschen
    Molecular Cardiology, Department of Internal Medicine III, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    J Am Coll Cardiol 45:229-37. 2005
    ..The goal of this study was to determine the predictive value of pregnancy-associated plasma protein-A (PAPP-A) in patients with acute coronary syndromes (ACS)...
  14. ncbi request reprint The pro-apoptotic serum activity is an independent mortality predictor of patients with heart failure
    Lothar Rossig
    Division of Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Eur Heart J 25:1620-5. 2004
    ..Since serum of patients with HF induces apoptosis of endothelial cells (EC), we aimed to determine whether the pro-apoptotic activity in the serum may predict prognosis of patients with HF...
  15. ncbi request reprint Interleukin-10 serum levels and systemic endothelial vasoreactivity in patients with coronary artery disease
    Stephan Fichtlscherer
    Department of Internal Medicine IV, Division of Cardiology, Johann W Goethe University, Frankfurt, Germany
    J Am Coll Cardiol 44:44-9. 2004
    ..Because the endothelium is a major target for inflammatory cytokines, we investigated whether elevated interleukin (IL)-10 serum levels are associated with improved endothelial vasoreactivity in patients with coronary artery disease (CAD)...
  16. ncbi request reprint Inflammatory markers and coronary artery disease
    Stephan Fichtlscherer
    Johann W Goethe University, Department of Cardiology, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Curr Opin Pharmacol 4:124-31. 2004
    ..As a result, different markers are used clinically for risk stratification in stable coronary artery disease as well as in acute coronary syndromes...
  17. ncbi request reprint Quantitative bedside testing of troponin T: is it equal to laboratory testing? The Cardiac Reader Troponin T (CARE T) study
    Britta U Goldmann
    Med Clinic III Division of Cardiology, University Hospital Eppendorf, Hamburg, Germany
    Clin Lab 50:1-10. 2004
    ..However, point-of-care testing of troponin T is advantageous whenever marker results could positively effect initial triage decisions and interventional management choices...
  18. ncbi request reprint Prognostic value of placental growth factor in patients with acute chest pain
    Christopher Heeschen
    Department of Cardiology, Johann Wolfgang Goethe University, Frankfurt, Germany
    JAMA 291:435-41. 2004
    ....
  19. ncbi request reprint Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization
    Christopher Heeschen
    Department of Internal Medicine IV and Hematology, University of Frankfurt, Germany
    Blood 102:1340-6. 2003
    ..Epo appears to physiologically regulate EPC mobilization in patients with ischemic heart disease. Thus, Epo serum levels may help in identifying patients with impaired EPC recruitment capacity...
  20. ncbi request reprint Soluble CD40 ligand in acute coronary syndromes
    Christopher Heeschen
    c7E3 Fab Antiplatelet Therapy in Unstable Refractory Angina CAPTURE Study, Department of Internal Medicine IV, University of Frankfurt, Frankfurt, Germany
    N Engl J Med 348:1104-11. 2003
    ..We investigated the predictive value of soluble CD40 ligand as a marker for clinical outcome and the therapeutic effect of glycoprotein IIb/IIIa receptor inhibition in patients with acute coronary syndromes...
  21. ncbi request reprint Withdrawal of statins increases event rates in patients with acute coronary syndromes
    Christopher Heeschen
    University Hospital Frankfurt, Germany
    Circulation 105:1446-52. 2002
    ..Withdrawal of chronic statin treatment during acute coronary syndromes may impair vascular function independent of lipid-lowering effects and thus increase cardiac event rate...