M Worm

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Increased leukotriene production by food additives in patients with atopic dermatitis and proven food intolerance
    M Worm
    Humboldt University, Department of Dermatology and Allergy, Charite Campus Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    Clin Exp Allergy 31:265-73. 2001
  2. ncbi request reprint Prevalence of adverse reactions to food in Germany - a population study
    T Zuberbier
    Department of Dermatology and Allergy, University Hospital Charite, Humboldt University, Germany
    Allergy 59:338-45. 2004
  3. doi request reprint Efficient tetanus toxoid immunization on vitamin D supplementation
    G Heine
    Klinik fur Dermatologie, Venerologie und Allergologie, Allergie Centrum Charité, CCM, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur J Clin Nutr 65:329-34. 2011
  4. doi request reprint Allergenic activity of different tomato cultivars in tomato allergic subjects
    S Dölle
    Department of Dermatology and Allergology, Charite Universitatsmedizin, Berlin, Germany
    Clin Exp Allergy 41:1643-52. 2011
  5. ncbi request reprint Retinoic acid inhibits CD40 + interleukin-4-mediated IgE production in vitro
    M Worm
    Department of Dermatology, Charite Virchow Klinikum, Humboldt Universität and Deutsches Rheuma Forschungszentrum, Berlin, Germany
    Blood 92:1713-20. 1998
  6. ncbi request reprint Hypocomplementaemic urticarial vasculitis: successful treatment with cyclophosphamide-dexamethasone pulse therapy
    M Worm
    Department of Dermatology, Charité Clinic, Humboldt University, Schumannstr 20 21, D 10117 Berlin, Germany
    Br J Dermatol 139:704-7. 1998
  7. ncbi request reprint Food allergy and non-allergic food hypersensitivity in children and adolescents
    C C Roehr
    Department of Pediatric Pneumology and Immunology, University Hospital Charite, Humboldt University, Berlin, Germany
    Clin Exp Allergy 34:1534-41. 2004
  8. ncbi request reprint Cutaneous side-effects in patients with rheumatic diseases during application of tumour necrosis factor-alpha antagonists
    H H Lee
    Department of Dermatology and Allergy, Charite Universitatsmedizin Berlin, D 10117 Berlin, Germany
    Br J Dermatol 156:486-91. 2007
  9. doi request reprint Tamoxifen counteracts the allergic immune response and improves allergen-induced dermatitis in mice
    M Babina
    Department of Dermatology and Allergy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Clin Exp Allergy 40:1256-65. 2010
  10. ncbi request reprint Effects of retinoids on in vitro and in vivo IgE production
    M Worm
    Department of Dermatology, Charite Virchow Klinikum, Humboldt Universitat Berlin, Germany
    Int Arch Allergy Immunol 124:233-6. 2001

Detail Information

Publications45

  1. ncbi request reprint Increased leukotriene production by food additives in patients with atopic dermatitis and proven food intolerance
    M Worm
    Humboldt University, Department of Dermatology and Allergy, Charite Campus Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    Clin Exp Allergy 31:265-73. 2001
    ..These findings indicate that single food additives as aggravating factors in AD patients may trigger the disease through increased sLT production as a pathophysiological mechanism...
  2. ncbi request reprint Prevalence of adverse reactions to food in Germany - a population study
    T Zuberbier
    Department of Dermatology and Allergy, University Hospital Charite, Humboldt University, Germany
    Allergy 59:338-45. 2004
    ..A population study was performed to identify the prevalence of all kinds of adverse reactions to food...
  3. doi request reprint Efficient tetanus toxoid immunization on vitamin D supplementation
    G Heine
    Klinik fur Dermatologie, Venerologie und Allergologie, Allergie Centrum Charité, CCM, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur J Clin Nutr 65:329-34. 2011
    ..The supplementation of vitamin D might be therapeutically beneficial, for example, in lupus erythematosus patients. However, its affect on established recall immune responses is undefined...
  4. doi request reprint Allergenic activity of different tomato cultivars in tomato allergic subjects
    S Dölle
    Department of Dermatology and Allergology, Charite Universitatsmedizin, Berlin, Germany
    Clin Exp Allergy 41:1643-52. 2011
    ..Therefore, identification of tomato cultivars with reduced allergenicity would potentially increase the quality of life of affected subjects...
  5. ncbi request reprint Retinoic acid inhibits CD40 + interleukin-4-mediated IgE production in vitro
    M Worm
    Department of Dermatology, Charite Virchow Klinikum, Humboldt Universität and Deutsches Rheuma Forschungszentrum, Berlin, Germany
    Blood 92:1713-20. 1998
    ..Taken together, this study shows that RA inhibits IgE production of anti-CD40 + IL-4-stimulated B cells in vitro...
  6. ncbi request reprint Hypocomplementaemic urticarial vasculitis: successful treatment with cyclophosphamide-dexamethasone pulse therapy
    M Worm
    Department of Dermatology, Charité Clinic, Humboldt University, Schumannstr 20 21, D 10117 Berlin, Germany
    Br J Dermatol 139:704-7. 1998
    ..These cases indicate that cyclophosphamide-dexamethasone pulse therapy is efficient in the treatment of hypocomplementaemic urticarial vasculitis...
  7. ncbi request reprint Food allergy and non-allergic food hypersensitivity in children and adolescents
    C C Roehr
    Department of Pediatric Pneumology and Immunology, University Hospital Charite, Humboldt University, Berlin, Germany
    Clin Exp Allergy 34:1534-41. 2004
    ..Little information is available on the prevalence of food hypersensitivity in unselected paediatric populations. No data were available for German children...
  8. ncbi request reprint Cutaneous side-effects in patients with rheumatic diseases during application of tumour necrosis factor-alpha antagonists
    H H Lee
    Department of Dermatology and Allergy, Charite Universitatsmedizin Berlin, D 10117 Berlin, Germany
    Br J Dermatol 156:486-91. 2007
    ..Patients with rheumatic diseases receiving antitumour necrosis factor (TNF)-alpha-based treatment may develop cutaneous reactions...
  9. doi request reprint Tamoxifen counteracts the allergic immune response and improves allergen-induced dermatitis in mice
    M Babina
    Department of Dermatology and Allergy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Clin Exp Allergy 40:1256-65. 2010
    ..We hypothesized that TX might inhibit type I allergic reactions, which are also characterized by deviations in humoral immunity...
  10. ncbi request reprint Effects of retinoids on in vitro and in vivo IgE production
    M Worm
    Department of Dermatology, Charite Virchow Klinikum, Humboldt Universitat Berlin, Germany
    Int Arch Allergy Immunol 124:233-6. 2001
    ..The aim of the present study was to extend these findings regarding the potential use of retinoids for the treatment of allergic diseases...
  11. doi request reprint Targeting the vitamin D receptor inhibits the B cell-dependent allergic immune response
    B Hartmann
    Allergie Centrum Charité, CCM, Klinik für Dermatologie und Allergologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Allergy 66:540-8. 2011
    ..This study aimed to investigate the impact of a low-calcemic VDR agonist on the IgE immune response in vitro and in vivo...
  12. ncbi request reprint A combination of wheat flour, ethanol and food additives inducing FDEIA
    E M Fiedler
    Department of Dermatology and Allergy, University Clinic Charite, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Allergy 57:1090-1. 2002
  13. doi request reprint Skin sclerosis is only of limited value to identify SSc patients with severe manifestations--an analysis of a distinct patient subgroup of the German Systemic Sclerosis Network (DNSS) Register
    L G Hanitsch
    Clinic of Rheumatology and Clinical Immunology, Charite Universitatsmedizin, Charite, Berlin, Germany
    Rheumatology (Oxford) 48:70-3. 2009
    ..In SSc, diagnosis and classification is based mainly on skin sclerosis. Herein, we investigated in a large multicentre cohort, to what extent skin sclerosis reflects organ involvement and additional clinical symptoms...
  14. ncbi request reprint Sugar is not an aggravating factor in atopic dermatitis
    I Ehlers
    Department of Dermatology and Allergy, Charite, Humboldt University, Berlin, Germany
    Acta Derm Venereol 81:282-4. 2001
    ..From these results, we conclude that sugar is not an aggravating factor in atopic dermatitis, which contradicts the view of many patients and underlines the importance of evidence-based medicine in the guidance of patients...
  15. doi request reprint Allergen extract-induced interleukin-10 in human memory B cells inhibits immunoglobulin E production
    M Milovanovic
    Department of Dermatology and Allergy, Allergy Center Charité, CCM, Charite Universitatsmedizin Berlin, Berlin, Germany
    Clin Exp Allergy 39:671-8. 2009
    ..The induction of antigen-specific IL-10 secreting T cells is discussed as an important mechanism during specific immunotherapy. By contrast the presence and function of B cell-derived IL-10 is not well defined yet...
  16. doi request reprint Gastrointestinal nematode infection interferes with experimental allergic airway inflammation but not atopic dermatitis
    S Hartmann
    Department of Molecular Parasitology, Humboldt University Berlin, Berlin, Germany
    Clin Exp Allergy 39:1585-96. 2009
    ....
  17. ncbi request reprint Allergen-mediated modulation of CD23 expression is interferon-gamma and interleukin-10 dependent in allergic and non-allergic individuals
    A C Roever
    Department of Dermatology and Allergy, Charite Campus Mitte, Humboldt University, Berlin, Germany
    Clin Exp Allergy 33:1568-75. 2003
    ..In the present study, we investigated in detail the effects of complete birch pollen allergen extract (BPA) on CD23 expression of peripheral blood mononuclear cells (PBMCs) in vitro...
  18. doi request reprint Association of the toll-like receptor 2 A-16934T promoter polymorphism with severe atopic dermatitis
    D Y Oh
    Institut für Mikrobiologie und Hygiene, Allergie Centrum Charité, CCM, Charite Universitatsmedizin Berlin, Berlin, Germany
    Allergy 64:1608-15. 2009
    ..A genetically determined defective function of pattern recognition receptors such as toll-like receptors (TLRs) has been proposed as a candidate mechanism in the pathogenesis of AD...
  19. doi request reprint Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis
    S Dölle
    Charite Universitatsmedizin Berlin, Department of Dermatology and Allergology, Berlin, Germany
    Allergy 65:1158-65. 2010
    ..With this controlled clinical study, the clinical and immunomodulatory efficacy of miltefosine was investigated in patients with AD in comparison with a topical corticosteroid treatment...
  20. pmc New onset or exacerbation of psoriatic skin lesions in patients with definite rheumatoid arthritis receiving tumour necrosis factor alpha antagonists
    S Kary
    Department of Rheumatology and Clinical Immunology, Charite University Medicine Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Ann Rheum Dis 65:405-7. 2006
    ..Furthermore, TNFalpha antagonists have also been shown to significantly reduce psoriatic skin lesions...
  21. doi request reprint Insulin allergy: clinical manifestations and management strategies
    L Heinzerling
    Department of Dermatology and Allergy, Charite Universitatsmedizin, Berlin, Germany
    Allergy 63:148-55. 2008
    ..It can be managed well in close cooperation between the diabetologist and the allergologist. Specific immunotherapy is efficient and should be considered...
  22. ncbi request reprint Efficacy and safety of methylprednisolone aceponate ointment 0.1% compared to tacrolimus 0.03% in children and adolescents with an acute flare of severe atopic dermatitis
    T Bieber
    Department of Dermatology, University of Bonn, Bonn, Germany
    Allergy 62:184-9. 2007
    ..This study compared efficacy and safety of 0.1% methylprednisolone aceponate (MPA) ointment with 0.03% tacrolimus ointment for 3 weeks, in children and adolescents with severe to very severe flare of AD...
  23. ncbi request reprint Type-IV sensitization profile of individuals with atopic eczema: results from the Information Network of Departments of Dermatology (IVDK) and the German Contact Dermatitis Research Group (DKG)
    G Heine
    Klinik fur Dermatologie, Venerologie und Allergologie, Allergie Centrum Charité Campus Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Allergy 61:611-6. 2006
    ..2%) and hand dermatitis (6.6%) was more common, and leg dermatitis (4.0%) less common. Analysis of occupation, suspected allergen source, and accompanying factors revealed no major differences between the both groups...
  24. ncbi request reprint Cytokine and Ig-production by CG-containing sequences with phosphorodiester backbone and dumbbell-shape
    M Schmidt
    Mologen AG, Berlin, Germany
    Allergy 61:56-63. 2006
    ..Immunostimulatory oligodeoxynucleotides (CpG-ODN) usually contain phosphorothioate (PS) backbones for nucleotide protection, which may result in some nonspecific side-effects like prolongation of coagulation time...
  25. doi request reprint GA² LEN/EAACI pocket guide for allergen-specific immunotherapy for allergic rhinitis and asthma
    T Zuberbier
    Department of Dermatology and Allergy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Allergy 65:1525-30. 2010
    ..The recommendations cover patient selection, allergen extract to be used, route of administration of SIT (in particular, sublingual and subcutaneous immunotherapy), and necessary precautions to be followed in using SIT...
  26. pmc Impaired T cell activation and cytokine production by calcitriol-primed human B cells
    G Drozdenko
    Klinik fur Dermatologie, Venerologie und Allergologie, Allergie Centrum Charité, CCM, Charite Universitatsmedizin Berlin, Berlin, Germany
    Clin Exp Immunol 178:364-72. 2014
    ..Taken together, we identified a novel B cell-dependent vitamin D immune regulatory mechanism, namely by decreased co-stimulation of calcitriol-primed B cells...
  27. doi request reprint Association of vitamin D receptor gene polymorphisms with severe atopic dermatitis in adults
    G Heine
    Klinik fur Dermatologie, Venerologie und Allergologie, Allergie Centrum Charité, CCM, Charite Universitatsmedizin Berlin, Berlin, Germany
    Br J Dermatol 168:855-8. 2013
    ..Vitamin D mediates immunomodulatory functions, and beneficial functions in allergic diseases have been suggested. Vitamin D receptor gene (VDR) polymorphisms are known but have not been studied in patients with atopic dermatitis (AD)...
  28. doi request reprint Symptom profile and risk factors of anaphylaxis in Central Europe
    M Worm
    Department of Dermatology and Allergy, University Hospital Charite, Berlin, Germany
    Allergy 67:691-8. 2012
    ..Standardized acquired clinical data from large cohorts of well-defined cases are not available. The aim of this study was to analyse the symptom profile and risk factors of anaphylaxis in a large Central European cohort...
  29. doi request reprint Low-dose cyclosporine A therapy increases the regulatory T cell population in patients with atopic dermatitis
    C Brandt
    Deutsches Rheuma ForschungsZentrum, Berlin, Germany
    Allergy 64:1588-96. 2009
    ..We studied the impact of low-dose CsA therapy on the ability of T helper cells to be activated, and examined whether regulatory T (Treg) cells are increased in these patients...
  30. ncbi request reprint Penetration of pollen proteins into the skin
    U Jacobi
    Department of Dermatology and Allergology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Skin Pharmacol Physiol 20:297-304. 2007
    ..To evaluate such strategies, the developed method can be used, and further studies in atopic dermatitis patients are necessary to determine whether the penetration of type I allergens is increased...
  31. ncbi request reprint Nevoid bag-like soft fibromas
    M Worm
    Department of Dermatology, Charite, Humboldt University, Berlin, Germany
    Dermatology 199:167-8. 1999
    ..We suggest that these nevoid bag-like soft fibromas represent a new malformation in the heterogenous group of nevoid tumors...
  32. doi request reprint Impact of systemic alitretinoin treatment on skin barrier gene and protein expression in patients with chronic hand eczema
    V Kumari
    Department of Dermatology and Allergy, Allergy Center Charité, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
    Br J Dermatol . 2016
    ..Chronic hand eczema (CHE) is a common inflammatory skin disease that affects approximately 10% of the population. Systemic alitretinoin has been shown to be effective in patients with CHE who are refractory to topical corticosteroids...
  33. pmc Standardization of double blind placebo controlled food challenge with soy within a multicentre trial
    R Treudler
    Department of Dermatology, Venerology and Allergology, Universitat Leipzig, Leipzig, Germany Leipziger Interdisziplinäres Centrum für Allergologie LICA Comprehensive Allergy Centre CAC, Klinik fur Dermatologie, Venerologie und Allergologie, Universitatsklinikum Leipzig, Philipp Rosenthal Straße 23, 04103 Leipzig, Germany
    Clin Transl Allergy 6:39. 2016
    ..We aimed at developing a standardized approach for identifying patients with birch related soy allergy by means of DBPCFC to soy, including determination of threshold levels, in a multicentre setting...
  34. doi request reprint First European data from the network of severe allergic reactions (NORA)
    M Worm
    Department of Dermatology and Allergy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Allergy 69:1397-404. 2014
    ..Occurrence, elicitors and treatment of severe allergic reactions are recognized and reported differently between countries. We aimed to collect standardized data throughout Europe on anaphylaxis referred for diagnosis and counselling...
  35. ncbi request reprint Subclinical activation of latent cytomegalovirus (CMV) infection and anti-CMV immune response in patients with atopic dermatitis
    W D Docke
    Institute of Medical Immunology, Department of Dermatology, University Hospital Charite, Berlin Humboldt University, D 10098 Berlin, Germany
    Br J Dermatol 148:954-63. 2003
    ..This, however, is of interest because of the high prevalence of latent infections in the general population, the frequent reactivation in inflammatory diseases, and the immunomodulating capacity of CMV...
  36. doi request reprint Anaphylaxis in an emergency setting - elicitors, therapy and incidence of severe allergic reactions
    K Beyer
    Department of Dermatology and Allergology, Charité University Medical Centre, Berlin, Germany
    Allergy 67:1451-6. 2012
    ..5-2.0%. The prevalence and incidence of anaphylactic reactions in Germany are unknown. We therefore assessed anaphylactic patients seen by emergency physicians in the Berlin area covering 4 million people...
  37. doi request reprint Comparison of patients with and without digital ulcers in systemic sclerosis: detection of possible risk factors
    C Sunderkotter
    Department of Dermatology, University of Munster, Von Esmarch Str 58, 48149 Munster, Germany
    Br J Dermatol 160:835-43. 2009
    ..For optimal management it would be useful to identify the risk factors for DU. Such statistical analyses have been rare because they require a high number of patients...
  38. ncbi request reprint Type I sensitization towards patent blue as a cause of anaphylaxis
    K Forschner
    Department of Dermatology and Allergy, Charite, Humboldt University, Schumannstrasse 20 21 D 10117, Berlin, Germany
    Allergy 58:457-8. 2003
  39. ncbi request reprint Novel unconventional therapeutic approaches to atopic eczema
    M Worm
    Department of Dermatology and Allergy, Charite, Humboldt University, Berlin, Germany
    Dermatology 201:191-5. 2000
    ..Any new type of unconventional therapy should thus be thoroughly evaluated and shown to be equal or superior to conventional treatments with regard to both efficacy and tolerability before it is recommended for use in clinical practice...
  40. ncbi request reprint Neutrophil respiratory burst is decreased in scleroderma and normalized by near-infrared mediated hyperthermia
    J Foerster
    Department of Dermatology, Charite Hospital, Berlin, Germany
    Clin Exp Dermatol 31:799-806. 2006
    ..The production of reactive oxygen species (ROS) by fibroblasts has been suggested to contribute to scleroderma pathogenesis. Infrared-mediated hyperthermia has recently been shown to be of benefit in scleroderma...
  41. doi request reprint Contact sensitization in patients with suspected cosmetic intolerance: results of the IVDK 2006-2011
    A Dinkloh
    Department of Dermatology, Venereology and Allergy, Charite Universitatsmedizin, Berlin, Germany
    J Eur Acad Dermatol Venereol 29:1071-81. 2015
    ..Ingredients of leave-on cosmetics and body care products may sensitize. However, not every case of cosmetic intolerance is due to contact sensitization...
  42. doi request reprint Thymic stromal lymphopoietin induction by skin irritation is independent of tumour necrosis factor-α, but supported by interleukin-1
    V Kumari
    Klinik für Dermatologie und Allergologie, Allergie Centrum Charité, CCM, Charite Universitatsmedizin, 10117, Berlin, Germany
    Br J Dermatol 172:951-60. 2015
    ..Thymic stromal lymphopoietin (TSLP) is an extensively studied cytokine linked to the pathogenesis of allergic diseases, but the inherent activities behind TSLP expression are not well defined...
  43. ncbi request reprint Ethanol as a cause of hypersensitivity reactions to alcoholic beverages
    I Ehlers
    Department of Dermatology and Allergy, Charite, Hamboldt University, Berlin, Germany
    Clin Exp Allergy 32:1231-5. 2002
    ..By contrast pure ethanol has rarely been reported as a cause of hypersensitivity reactions and its mechanism has not been clarified yet...
  44. pmc Lysis of allogeneic and autologous melanoma cells by IL-7-induced lymphokine-activated killer cells
    M Bohm
    University Hospital Rudolf Virchow, Department of Dermatology, Free University of Berlin, Germany
    Br J Cancer 70:54-9. 1994
    ..These results suggest that IL-7 is a potential alternative to immunotherapy with IL-2 in terms of efficacy and possible side-effects and encourages pilot studies with IL-7 in melanoma patients...
  45. ncbi request reprint Mast cells as initiators of immunity and host defense
    B M Henz
    Department of Dermatology, Humboldt University, Berlin, Germany
    Exp Dermatol 10:1-10. 2001
    ..While these data require further clarification, the basic ability of mast cells to initiate innate and acquired immune reactions can no longer be questioned...