Georg Seifert

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. pmc Regional hyperthermia combined with chemotherapy in paediatric, adolescent and young adult patients: current and future perspectives
    Georg Seifert
    Department of Paediatric Oncology and Haematology, Otto Heubner Centrum für Kinder und Jugendmedizin, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Radiat Oncol 11:65. 2016
  2. pmc Improvement of circadian rhythm of heart rate variability by eurythmy therapy training
    Georg Seifert
    Task Force Integrative Medicine in Pediatric Oncology, Department of Pediatric Oncology and Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine OHC, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Evid Based Complement Alternat Med 2013:564340. 2013
  3. doi request reprint Improvement of heart rate variability by eurythmy therapy after a 6-week eurythmy therapy training
    Georg Seifert
    Department of Pediatric Oncology and Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine, Charite, Universitatsmedizin Berlin, Germany
    Integr Cancer Ther 11:111-9. 2012
  4. doi request reprint Anthroposophic supportive treatment in children with medulloblastoma receiving first-line therapy
    Georg Seifert
    Department of Pediatric Oncology and Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine OHC, Charite, Universitatsmedizin Berlin, Berlin
    J Pediatr Hematol Oncol 33:e105-8. 2011
  5. doi request reprint Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro
    Georg Seifert
    Department of Pediatric Oncology Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine, Charite, Universitatsmedizin Berlin, Germany
    Cancer Lett 264:218-28. 2008
  6. ncbi request reprint Genetic investigations of Saethre-Chotzen syndrome presenting with renal cell carcinoma
    Georg Seifert
    Department of Pediatric Oncology Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine OHC, Charite, Universitatsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany
    Cancer Genet Cytogenet 171:76-8. 2006
  7. ncbi request reprint Fatal course after administration of rituximab in a boy with relapsed all: a case report and review of literature
    Georg Seifert
    Charite, Universitatsmedizin Berlin, Germany
    Haematologica 91:ECR23. 2006
  8. pmc Intraluminal instillation of urokinase and autologous plasma: a method to unblock occluded central venous ports
    Georg Seifert
    Department of Paediatric Oncology Haematology, Charite Universitatsmedizin Berlin, Germany
    BMC Cancer 6:103. 2006
  9. ncbi request reprint Response to subcutaneous therapy with mistletoe in recurrent multisystem Langerhans cell histiocytosis
    Georg Seifert
    Department of Pediatric Oncology Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine, Charite Universitatsmedizin Berlin, Germany
    Pediatr Blood Cancer 48:591-2. 2007
  10. doi request reprint Effects of complementary eurythmy therapy on heart rate variability
    Georg Seifert
    Department of Pediatric Oncology and Hematology, Charite Universitatsmedizin Berlin, Germany
    Complement Ther Med 17:161-7. 2009

Collaborators

Detail Information

Publications22

  1. pmc Regional hyperthermia combined with chemotherapy in paediatric, adolescent and young adult patients: current and future perspectives
    Georg Seifert
    Department of Paediatric Oncology and Haematology, Otto Heubner Centrum für Kinder und Jugendmedizin, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Radiat Oncol 11:65. 2016
    ....
  2. pmc Improvement of circadian rhythm of heart rate variability by eurythmy therapy training
    Georg Seifert
    Task Force Integrative Medicine in Pediatric Oncology, Department of Pediatric Oncology and Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine OHC, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Evid Based Complement Alternat Med 2013:564340. 2013
    ....
  3. doi request reprint Improvement of heart rate variability by eurythmy therapy after a 6-week eurythmy therapy training
    Georg Seifert
    Department of Pediatric Oncology and Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine, Charite, Universitatsmedizin Berlin, Germany
    Integr Cancer Ther 11:111-9. 2012
    ..Furthermore, a long-term improvement of quality of life (QoL) and stress coping strategies by EYT could be shown...
  4. doi request reprint Anthroposophic supportive treatment in children with medulloblastoma receiving first-line therapy
    Georg Seifert
    Department of Pediatric Oncology and Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine OHC, Charite, Universitatsmedizin Berlin, Berlin
    J Pediatr Hematol Oncol 33:e105-8. 2011
    ..The question was whether the effectiveness of the first-line therapy is altered by AM...
  5. doi request reprint Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro
    Georg Seifert
    Department of Pediatric Oncology Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine, Charite, Universitatsmedizin Berlin, Germany
    Cancer Lett 264:218-28. 2008
    ..Both MTs significantly improved survival (up to 55.4 days) at all tested concentrations in contrast to controls (34.6 days) without side effects...
  6. ncbi request reprint Genetic investigations of Saethre-Chotzen syndrome presenting with renal cell carcinoma
    Georg Seifert
    Department of Pediatric Oncology Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine OHC, Charite, Universitatsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany
    Cancer Genet Cytogenet 171:76-8. 2006
    ..Here, we present immunological and genetic investigations including the determination of a new stop codon mutation in the TWIST1 gene in SCS associated with malignancy in childhood...
  7. ncbi request reprint Fatal course after administration of rituximab in a boy with relapsed all: a case report and review of literature
    Georg Seifert
    Charite, Universitatsmedizin Berlin, Germany
    Haematologica 91:ECR23. 2006
    ..The fatal course will be discussed based on a review of the literature...
  8. pmc Intraluminal instillation of urokinase and autologous plasma: a method to unblock occluded central venous ports
    Georg Seifert
    Department of Paediatric Oncology Haematology, Charite Universitatsmedizin Berlin, Germany
    BMC Cancer 6:103. 2006
    ..Therapeutic use and effective function of recombinant urokinase (r-UK) for occluded ports need the presence of plasminogen...
  9. ncbi request reprint Response to subcutaneous therapy with mistletoe in recurrent multisystem Langerhans cell histiocytosis
    Georg Seifert
    Department of Pediatric Oncology Hematology, Otto Heubner Center for Pediatric and Adolescent Medicine, Charite Universitatsmedizin Berlin, Germany
    Pediatr Blood Cancer 48:591-2. 2007
    ..Through the use of subcutaneous therapy with mistletoe (MT), an inactive disease state was achieved...
  10. doi request reprint Effects of complementary eurythmy therapy on heart rate variability
    Georg Seifert
    Department of Pediatric Oncology and Hematology, Charite Universitatsmedizin Berlin, Germany
    Complement Ther Med 17:161-7. 2009
    ..EYT can lead to long-term alleviation of chronic disease symptoms and improve patient quality of life. Yet, little is known about underlying physiological mechanisms...
  11. doi request reprint Eurythmy therapy in the aftercare of pediatric posterior fossa tumour survivors--a pilot study
    Jenny Lena Kanitz
    Department of Pediatric Oncology and Hematology, Task Force Integrative Medicine in Pediatric Oncology, Charite Universitatsmedizin Berlin, Germany
    Complement Ther Med 21:S3-9. 2013
    ..g. in cancer patients. This pilot study is a first attempt to assess the feasibility, treatment adherence and impact of eurythmy therapy (EYT) in pediatric neurooncology...
  12. doi request reprint The impact of eurythmy therapy on stress coping strategies and health-related quality of life in healthy, moderately stressed adults
    Jenny Lena Kanitz
    Department of Pediatric Oncology and Hematology, Task Force Integrative Medicine in Pediatric Oncology, Charite Universitatsmedizin Berlin, Germany
    Complement Ther Med 19:247-55. 2011
    ..The purpose of this study was to investigate the impact of EYT on stress coping strategies (SCS) and HRQoL in a controlled study with moderately stressed participants...
  13. doi request reprint Apoptosis-inducing activity of Helleborus niger in ALL and AML
    Patrick Jesse
    Department of Pediatric Oncology Hematology, Charite, Universitatsmedizin Berlin, Berlin, Germany
    Pediatr Blood Cancer 52:464-9. 2009
    ..Indications include various types of brain tumors in children, as well as prostate cancer, leukemia and lymphoma. Our aim was to investigate the therapeutic effects of these extracts apart from the traditional use...
  14. pmc Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing Sarcoma
    Monika Twardziok
    Department of Pediatric Oncology Hematology, Otto Heubner Centre for Pediatric and Adolescent Medicine OHC, Charite, Universitatsmedizin Berlin, Germany
    PLoS ONE 11:e0159749. 2016
    ..ViscumTT also demonstrated strong antitumor activity in a cell line- and patient-derived mouse model, and may be considered an adjuvant therapy option for pediatric patients with Ewing sarcoma. ..
  15. ncbi request reprint Brief communication: stability and catalytic activity of novel circular DNAzymes
    Georg Seifert
    Charite Universitatsmedizin Berlin, Otto Heubner Center for Pediatric and Adolescent Medicine OHC, Department of Pediatric Oncology Hematology, Berlin, Germany
    Nucleosides Nucleotides Nucleic Acids 25:785-93. 2006
    ..Thus, improving the stability of DNAzymes without reducing their catalytic activity is essential if the potential of these compounds should be realized in vivo...
  16. pmc Impact of Mistletoe Triterpene Acids on the Uptake of Mistletoe Lectin by Cultured Tumor Cells
    Katharina Mulsow
    Institute of Pharmacy, Department of Pharmaceutical Biology, Freie Universitaet Berlin, Berlin, Germany
    PLoS ONE 11:e0153825. 2016
    ..Interestingly, the uptake of ML by 143B-cells could only be measured after addition of triterpenes pointing to resistance to mistletoe lectin. ..
  17. pmc Heart rate variability reflects the natural history of physiological development in healthy children and is not associated with quality of life
    Georg Seifert
    Charite Universitatsmedizin Berlin, Department of Paediatric Oncology and Haematology, Berlin, Germany
    PLoS ONE 9:e91036. 2014
    ..Various psychometric instruments have been developed for use in paediatric oncology. The aim of this study was to obtain data on HRV and QoL and their correlations, initially in healthy children...
  18. doi request reprint A randomised, controlled, single-blinded study on the impact of a single rhythmical massage (anthroposophic medicine) on well-being and salivary cortisol in healthy adults
    Jenny Lena Kanitz
    Department of Paediatric Oncology and Haematology, Task Force Integrative Medicine in Paediatric Oncology, Charite Universitatsmedizin, Berlin, Germany Electronic address
    Complement Ther Med 23:685-92. 2015
    ....
  19. pmc ViscumTT induces apoptosis and alters IAP expression in osteosarcoma in vitro and has synergistic action when combined with different chemotherapeutic drugs
    Susann Kleinsimon
    Department of Pediatric Oncology Hematology, Otto Heubner Centre for Pediatric and Adolescent Medicine OHC, Charitém, Universitatsmedizin, Augustenburger Platz 1, 13353, Berlin, Germany
    BMC Complement Altern Med 17:26. 2017
    ..In this study, a whole mistletoe extract viscumTT re-created by combining an aqueous extract (viscum) and a triterpene extract (TT) was tested for its anti-cancer potential in osteosarcoma...
  20. ncbi request reprint Deletion analysis of p16(INKa) and p15(INKb) in relapsed childhood acute lymphoblastic leukemia
    Hagen Graf Einsiedel
    Department of Pediatric Oncology Hematology, Charite Medical Center, Campus Virchow Klinikum, Humboldt University of Berlin, Germany
    Blood 99:4629-31. 2002
    ..There was no correlation between INK4 deletions and probability of event-free survival. These findings argue against an independent prognostic role of INK4 deletions in relapsed childhood ALL...
  21. pmc A Natural Combination Extract of Viscum album L. Containing Both Triterpene Acids and Lectins Is Highly Effective against AML In Vivo
    Catharina I Delebinski
    Department of Paediatric Oncology Haematology, Otto Heubner Centre for Paediatric and Adolescent Medicine OHC, Charite Universitaetsmedizin, Berlin, Germany
    PLoS ONE 10:e0133892. 2015
    ..These results suggest that the combination viscumTT may have a potential therapeutic value for the treatment AML. ..
  22. doi request reprint Keeping the balance--an overview of mind-body therapies in pediatric oncology
    Jenny Lena Kanitz
    Department of Pediatric Oncology and Hematology, Task Force Integrative Medicine in Pediatric Oncology, Charite Universitatsmedizin Berlin, Germany
    Complement Ther Med 21:S20-5. 2013
    ..Positive results include increased self-confidence and a more optimistic view in coping with the illness. We encourage clinicians to be more aware of the promising field of MBTs and its use in pediatric oncology...