K Miller

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint [Metastatic castration-resistant prostate cancer : Clinical data, new treatment options and therapy monitoring]
    K Miller
    Klinik für Urologie, Urologische Klinik, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Deutschland
    Urologe A 55:1206-12. 2016
  2. doi request reprint [Cardiovascular risks of androgen deprivation therapy for prostate cancer]
    K Miller
    Klinik und Hochschulambulanz für Urologie, Chariteplatz 1, 10117, Berlin, Deutschland
    Urologe A 55:627-31. 2016
  3. pmc Renal cell neoplasias: reversion-inducing cysteine-rich protein with Kazal motifs discriminates tumor subtypes, while extracellular matrix metalloproteinase inducer indicates prognosis
    Anja Rabien
    Department of Urology, Research Division, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin 10117, Germany
    J Transl Med 11:258. 2013
  4. pmc Staging lymphadenectomy in patients with localized high risk prostate cancer: comparison of the laparoendoscopic single site (LESS) technique with conventional multiport laparoscopy
    Frank Friedersdorff
    Department of Urology, Charite University Hospital, Chariteplatz 1, 10117 Berlin, Germany
    BMC Urol 14:92. 2014
  5. pmc Comparison of surgical technique (open vs. laparoscopic) on pathological and long term functional outcomes following radical prostatectomy
    Ahmed Magheli
    Department of Urology, Universitatsmedizin Berlin, Charité Campus Mitte and Benjamin Franklin, Berlin, Germany
    BMC Urol 14:18. 2014
  6. doi request reprint [Metastatic castration-resistant prostate cancer: position paper for structured therapy monitoring]
    K Miller
    Klinik für Urologie, Urologische Klinik, Charite Universitatsmedizin Berlin, CC 8 Chirurgische Medizin, Hindenburgdamm 30, 12200, Berlin, Deutschland
    Urologe A 53:710-4. 2014
  7. doi request reprint [Value of intermittent androgen deprivation in the context of the current data situation]
    K Miller
    Urologische Klinik, Charite, Berlin
    Aktuelle Urol 44:271-6. 2013
  8. pmc Laparoscopic and open postchemotherapy retroperitoneal lymph node dissection in patients with advanced testicular cancer--a single center analysis
    Jonas Busch
    Charite University Medicine Berlin, Department of Urology, Berlin, Germany
    BMC Urol 12:15. 2012
  9. pmc Interdisciplinary decision making in prostate cancer therapy - 5-years' time trends at the Interdisciplinary Prostate Cancer Center (IPC) of the Charité Berlin
    Daniel Baumunk
    Department of Urology and Pediatric Urology, Magdeburg University Medical Center, Leipziger Strasse 44, Magdeburg, D 39120, Germany
    BMC Med Inform Decis Mak 13:83. 2013
  10. doi request reprint Phase III, randomized, placebo-controlled study of once-daily oral zibotentan (ZD4054) in patients with non-metastatic castration-resistant prostate cancer
    K Miller
    Department of Urology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Prostate Cancer Prostatic Dis 16:187-92. 2013

Collaborators

Detail Information

Publications120 found, 100 shown here

  1. doi request reprint [Metastatic castration-resistant prostate cancer : Clinical data, new treatment options and therapy monitoring]
    K Miller
    Klinik für Urologie, Urologische Klinik, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Deutschland
    Urologe A 55:1206-12. 2016
    ....
  2. doi request reprint [Cardiovascular risks of androgen deprivation therapy for prostate cancer]
    K Miller
    Klinik und Hochschulambulanz für Urologie, Chariteplatz 1, 10117, Berlin, Deutschland
    Urologe A 55:627-31. 2016
    ..Cardiovascular side effects cannot be sufficiently explained by low testosterone levels. This review gives an overview of the recent literature, interprets the results, and offers clinical consequences. ..
  3. pmc Renal cell neoplasias: reversion-inducing cysteine-rich protein with Kazal motifs discriminates tumor subtypes, while extracellular matrix metalloproteinase inducer indicates prognosis
    Anja Rabien
    Department of Urology, Research Division, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin 10117, Germany
    J Transl Med 11:258. 2013
    ....
  4. pmc Staging lymphadenectomy in patients with localized high risk prostate cancer: comparison of the laparoendoscopic single site (LESS) technique with conventional multiport laparoscopy
    Frank Friedersdorff
    Department of Urology, Charite University Hospital, Chariteplatz 1, 10117 Berlin, Germany
    BMC Urol 14:92. 2014
    ..We compared outcomes after laparoendoscopic single site PL (LESSPL) with those after conventional multiport laparoscopic PL (MLPL)...
  5. pmc Comparison of surgical technique (open vs. laparoscopic) on pathological and long term functional outcomes following radical prostatectomy
    Ahmed Magheli
    Department of Urology, Universitatsmedizin Berlin, Charité Campus Mitte and Benjamin Franklin, Berlin, Germany
    BMC Urol 14:18. 2014
    ..Few studies to date have directly compared outcomes of retropubic (RRP) and laparoscopic (LRP) radical prostatectomy. We investigated a single institution experience with RRP and LRP with respect to functional and pathological outcomes...
  6. doi request reprint [Metastatic castration-resistant prostate cancer: position paper for structured therapy monitoring]
    K Miller
    Klinik für Urologie, Urologische Klinik, Charite Universitatsmedizin Berlin, CC 8 Chirurgische Medizin, Hindenburgdamm 30, 12200, Berlin, Deutschland
    Urologe A 53:710-4. 2014
    ..From a prognostic point of view, it is important that patients receive as many as possible and in the ideal case all currently available treatment options. ..
  7. doi request reprint [Value of intermittent androgen deprivation in the context of the current data situation]
    K Miller
    Urologische Klinik, Charite, Berlin
    Aktuelle Urol 44:271-6. 2013
    ..This review is intended to provide a code of practice for an individualised treatment as based on recently published studies. ..
  8. pmc Laparoscopic and open postchemotherapy retroperitoneal lymph node dissection in patients with advanced testicular cancer--a single center analysis
    Jonas Busch
    Charite University Medicine Berlin, Department of Urology, Berlin, Germany
    BMC Urol 12:15. 2012
    ..We analyzed laparoscopic postchemotherapy retroperitoneal lymph node dissection (L-PCLND) and O-PCLND at our institution...
  9. pmc Interdisciplinary decision making in prostate cancer therapy - 5-years' time trends at the Interdisciplinary Prostate Cancer Center (IPC) of the Charité Berlin
    Daniel Baumunk
    Department of Urology and Pediatric Urology, Magdeburg University Medical Center, Leipziger Strasse 44, Magdeburg, D 39120, Germany
    BMC Med Inform Decis Mak 13:83. 2013
    ....
  10. doi request reprint Phase III, randomized, placebo-controlled study of once-daily oral zibotentan (ZD4054) in patients with non-metastatic castration-resistant prostate cancer
    K Miller
    Department of Urology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Prostate Cancer Prostatic Dis 16:187-92. 2013
    ..This study, part of the ENTHUSE (EndoTHelin A USE) phase III programme, evaluated the efficacy and safety of the oral specific endothelin (ET)A receptor antagonist zibotentan vs placebo in patients with non-metastatic CRPC (non-mCRPC)...
  11. doi request reprint [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]
    K Miller
    Klinik für Urologie, Charite Universitatsmedizin Berlin
    Aktuelle Urol 44:45-9. 2013
    ..Results from the 2010 conference provided the basis for the 2011 meeting. The results of the 2011 conference are presented as short theses...
  12. doi request reprint [PSA progression under hormone therapy - of prognostic relevance?]
    K Miller
    Urologische Klinik und Hochschulambulanz Charité Berlin, Germany
    Aktuelle Urol 43:262-4. 2012
    ....
  13. pmc Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients
    Oliver Hohn
    Robert Koch Institute, Centre for Biological Safety 4, Nordufer 20, 13353 Berlin, Germany
    Retrovirology 6:92. 2009
    ..Here, we attempt to measure the prevalence of XMRV in prostate cancer cases in Germany and determine whether an analogous association with the R462Q polymorphism exists...
  14. pmc Impact of hormonal therapy on the detection of promoter hypermethylation of the detoxifying glutathione-S-transferase P1 gene (GSTP1) in prostate cancer
    Jens Kollermann
    Urologische Klinik, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    BMC Urol 6:15. 2006
    ..The purpose of our study was to assess the impact of endocrine therapy on the detection of GSTP1-HM by methylation-specific PCR (MSP) in prostate cancer...
  15. pmc Intrinsic resistance to tyrosine kinase inhibitors is associated with poor clinical outcome in metastatic renal cell carcinoma
    Jonas Busch
    Department of Hematology, Hemostases, Oncology and Stem Cell Transplantation, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    BMC Cancer 11:295. 2011
    ..Data on sequential therapy in patients with metastatic renal cell carcinoma (mRCC) and intrinsic resistance to receptor tyrosine kinase inhibitor (rTKI) treatment remains vague...
  16. pmc Down-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer
    Carsten Kempkensteffen
    Institute of Surgical Pathology, Universitatsspital Zurich, 8091 Zurich, Switzerland
    BMC Cancer 9:276. 2009
    ..However, little is yet known about its potential implication in the tumour biology of clear-cell renal cell cancer (ccRCC)...
  17. pmc Brain-type and liver-type fatty acid-binding proteins: new tumor markers for renal cancer?
    Angelika Tölle
    Department of Urology, Charite Universitatsmedizin Berlin, Berlin, Germany
    BMC Cancer 9:248. 2009
    ..We examined the level of brain-type (B) and liver-type (L) FABP mRNA and the protein expression profiles of both FABPs in renal cell carcinoma...
  18. ncbi request reprint [Carcinoma of the urinary bladder. Konservative oder operative Therapie bei PT1G3]
    K Miller
    Urologische Klinik, Charite, Campus Benjamin Franklin, Berlin
    Urologe A 44:151-4. 2005
    ..In this paper the advantages and disadvantages of primary cystectomy and of transurethral resection, both alone and in combination with BCG instillation, are discussed and compared...
  19. ncbi request reprint [The study landscape for prostate cancer]
    K Miller
    Urologische Klinik und Poliklinik, Charite Berlin
    Urologe A 44:1431-4. 2005
    ..The interdisciplinary study group of the AUO (Urology) and the ARO (Radio-oncology) has developed several new protocols which are currently under review by the German Cancer Aid (Deutsche Krebshilfe)...
  20. ncbi request reprint [Therapeutic options for hormone-refractory prostate cancer]
    K Miller
    Urologische Klinik, Charite, Campus Benjamin Franklin, Universitatsmedizin, Hindenburgdamm 30, 12200, Berlin, Germany
    Urologe A 45:580, 582-5. 2006
    ..Side effects include flu-like symptoms, muscle pain, and edemas. Zoledronic acid also belongs to the standard treatment of hormone-refractory prostate cancer with bone metastases...
  21. ncbi request reprint [Interdisciplinary recommendations concerning the therapy for hormone-refractory prostatic carcinoma]
    K Miller
    Charite Campus Benjamin Franklin, Universitatsmedizin, Berlin
    Aktuelle Urol 37:201-4. 2006
    ..Opinions differed with regard to the use of chemotherapy in asymptomatic patients. In addition, recommendations for the performance and monitoring of the therapy were formulated...
  22. ncbi request reprint [Therapy sequence for renal cell carcinoma--new aspects!]
    K Miller
    Urologische Klinik, Universitatsklinikum Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin
    Aktuelle Urol 38:59. 2007
    ..Besides a traumatic origin of retroperitoneal haemorrhage, the other most common cause is an anticoagulation therapy. Further potential sources of retroperitoneal hematoma are benign and malignant tumours of the adrenal gland...
  23. ncbi request reprint [Interdisciplinary recommendations on targeted therapy in the treatment of renal cell carcinoma]
    K Miller
    Urologische Klinik, Charite Berlin, Germany
    Aktuelle Urol 38:328-30. 2007
    ..This has raised both new opportunities and new questions for the health care professionals involved. Here we report on a consensus conference addressing these questions with answers based on evidence from the recent literature...
  24. doi request reprint [Adjuvant and neoadjuvant drug therapy for prostate cancer]
    K Miller
    Klinik und Hochschulambulanz für Urologie, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Deutschland
    Urologe A 47:1460-4. 2008
    ..For high-risk patients, long-term (2-3 years) adjuvant LHRH analog treatment is indicated...
  25. doi request reprint [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]
    K Miller
    Klinik für Urologie, Charite Universitatsmedizin Berlin, Berlin
    Aktuelle Urol 40:27-30. 2009
    ..Results from the 2007 conference provided the basis for the 2008 meeting. The results of the 2008 conference are presented as short theses...
  26. doi request reprint [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]
    K Miller
    Klinik für Urologie, Charite Universitatsmedizin Berlin
    Aktuelle Urol 41:193-6. 2010
    ..Results from the 2008 conference provided the basis for the 2009 meeting. The results of the 2009 conference are presented as short theses...
  27. doi request reprint [Castration resistant prostate cancer 2011]
    K Miller
    Urologische Klinik Charité, Berlin, Germany
    Aktuelle Urol 42:95-102. 2011
    ..Changing the term to castration resistant prostate cancer is one consequence of these new insights. Here we give an overview on the current situation of drug development, therapeutic consequences and future trends...
  28. doi request reprint [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]
    K Miller
    Klinik für Urologie, Charite Universitatsmedizin Berlin, Germany
    Aktuelle Urol 42:242-6. 2011
    ..Results from the 2009 conference provided the basis for the 2010 meeting. The results of the 2010 conference are presented as short theses...
  29. doi request reprint [Introduction of interdisciplinary prostate cancer centers based on the recommendations of the German Cancer Society. A cost-benefit analysis 3 years after accreditation]
    S Weikert
    Klinik für Urologie, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117, Berlin, Deutschland
    Urologe A 50:1083-8. 2011
    ..Short-term improvements in quality of care cannot be unequivocally demonstrated. Prostate cancer centers serve an important role in counseling and medical education and may thus help disseminate evidence-based treatment strategies...
  30. ncbi request reprint Telomerase activity and expression of telomerase subunits in the testicular tissue of infertile patients
    M Schrader
    Freie Universitat Berlin, Berlin, Germany
    Fertil Steril 73:706-11. 2000
    ..Determination of telomerase activity and the expression of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) in the testicular tissue of patients with infertility arising from various causes...
  31. doi request reprint [Testicular cancer - explanatory models for high cisplatin chemosensibility and new therapeutic options]
    J Ebbing
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin
    Aktuelle Urol 39:429-35. 2008
    ..Furthermore, the current data on alternative chemotherapies as well as of molecular, molecular-genetic and pharmacogenetic therapeutic concepts are explored. Data were obtained from researches in Medline of the Pubmed database...
  32. doi request reprint Expression parameters of the polycomb group proteins BMI1, SUZ12, RING1 and CBX7 in urothelial carcinoma of the bladder and their prognostic relevance
    S Hinz
    Department of Urology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Tumour Biol 29:323-9. 2008
    ....
  33. ncbi request reprint Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids
    C Goessl
    Department of Urology, Klinikum Benjamin Franklin, Freie Universitat Berlin, Germany
    Cancer Res 60:5941-5. 2000
    ..Analysis of GSTP1 promoter hypermethylation by MSP thus provides a specific tool for molecular diagnosis of prostate cancer in bodily fluids...
  34. pmc Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer
    F Christoph
    Department of Urology, Charite Campus Benjamin Franklin, Universitatsmedizin Berlin, Hindenburgdamm 30, Berlin 12200, and Institute of Pathoogy, University Hospital Hamburg Eppendorf, Germany
    Br J Cancer 95:1701-7. 2006
    ..In conclusion, demethylating agents effectively retard growth of TCC and RCC cell lines. Methylation level analysis of specific genes has the potential for further tumour characterisation in TCC and RCC...
  35. ncbi request reprint [Minimally invasive bone anchor in therapy of female stress incontinence. A good concept?]
    M Schostak
    Urologische Klinik, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Hindenburgdamm 30, 12200 Berlin
    Urologe A 40:107-13. 2001
    ..The technique of minimally invasive bone anchoring must be regarded as unsuitable in view of the largely poor wound healing associated with irritation symptoms...
  36. ncbi request reprint Reverse transcriptase-polymerase chain reaction for prostate-specific antigen in the molecular staging of pelvic surgical margins after radical prostatectomy
    B Straub
    Department of Urology, Klinikum Benjamin Franklin, , Berlin, Germany
    Urology 57:1006-11. 2001
    ..Long-term follow-up of these patients is needed to demonstrate the clinical value of molecular diagnostics of surgical margins during RP...
  37. ncbi request reprint DNA-based detection of prostate cancer in urine after prostatic massage
    C Goessl
    Department of Urology, Benjamin Franklin Medical School, Free University of Berlin, Berlin, Germany
    Urology 58:335-8. 2001
    ..CONCLUSIONS: Urinalysis for GSTP1 promoter hypermethylation constitutes a sensitive and highly specific DNA-based marker for molecular detection of prostate cancer, including early stages...
  38. ncbi request reprint ["Second opinion centers". Approach for improving the quality of treatment for testicular tumors]
    M Schrader
    Klinik für Urologie, Charite, Universitatsmedizin, Berlin Campus Benjamin Franklin, Freie Universitat Berlin
    Urologe A 45:493-4. 2006
    ..Our aim is to reduce the mortality rate by introducing a treatment procedure supported by a second opinion center...
  39. ncbi request reprint EZH2 polycomb transcriptional repressor expression correlates with methylation of the APAF-1 gene in superficial transitional cell carcinoma of the bladder
    S Hinz
    Department of Urology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Tumour Biol 28:151-7. 2007
    ..Moreover, these data present first evidence that APAF-1 methylation is related to transcriptional activity of EZH2 expression in early-stage tumor disease of the bladder...
  40. ncbi request reprint Detection of prostate-specific antigen RNA before and after radical retropubic prostatectomy and transurethral resection of the prostate using "Light-Cycler"-based quantitative real-time polymerase chain reaction
    B Straub
    Department of Urology, , , Berlin, Germany
    Urology 58:815-20. 2001
    ..Long-term follow-up of these patients with PCa must demonstrate the clinical value of molecular diagnostics with quantitative RT-PCR systems...
  41. ncbi request reprint Detection of germ-cell-tumor-specific gene products in peripheral blood by immunomagnetic tumor cell enrichment followed by RT-PCR
    M Schrader
    Klinik und Poliklinik fYr Urologie, CUB Campus Benjamin Franklin, Freie Universitat Berlin, 12200 Berlin, Germany
    Int J Mol Med 13:685-90. 2004
    ..Immunomagnetic enrichment of GCT cells in peripheral blood seems a promising approach for increasing the sensitivity of RT-PCR...
  42. ncbi request reprint Molecular markers in testicular germ cell tumors--objects of clinical research or close to becoming clinical tools?
    M Schrader
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Benjamin Franklin, Berlin
    Onkologie 24:144-8. 2001
    ....
  43. ncbi request reprint Molecular staging of surgical margins after radical prostatectomy by detection of telomerase activity
    B Straub
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Berlin, Germany
    Prostate 49:140-4. 2001
    ..We assessed the detection of telomerase activity using the telomeric repeat amplification protocol (TRAP) in surgical margins compared to conventional histopathological examination...
  44. ncbi request reprint Quantitative detection of cytokeratin 20 mRNA expression in bladder carcinoma by real-time reverse transcriptase-polymerase chain reaction
    F Christoph
    Department of Urology, Charite Campus Benjamin Franklin, Universitatsmedizin Berlin, Berlin, Germany
    Urology 64:157-61. 2004
    ....
  45. ncbi request reprint New guidelines for clinical stage I testicular seminoma?
    F Christoph
    Department of Urology, Charite, Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Oncology 69:455-62. 2005
    ....
  46. ncbi request reprint Quantitative detection of human complement factor H-related protein in transitional cell carcinoma of the urinary bladder
    R Heicappell
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat, Berlin, Germany
    Eur Urol 35:81-7. 1999
    ..The purpose of this study was to assess a new quantitative urinary tumor marker for transitional cell carcinoma of the urinary bladder (TCC), human complement factor H-related protein (hCFHrp, BTA TRAK)...
  47. ncbi request reprint Hyperphosphaturia after kidney transplantation in syngeneic rats: effects on nephrocalcinosis and bone metabolism?
    B Straub
    Department of Urology, Klinikum Benjamin Franklin, Freie Universitat, Berlin, Germany
    Transplant Proc 35:1575-80. 2003
    ..Experimental investigations in syngeneic rats were performed to see whether HPU also occurs after transplantation and thus after denervation and which target organs are involved...
  48. doi request reprint [Postoperative and adjuvant intravesical therapy of superficial bladder tumours. Clinical practice and applied therapeutic agents]
    Anja Lingnau
    Urologische Klinik und Hochschulambulanz, Charite Universitatsmedizin Berlin, Berlin
    Aktuelle Urol 40:307-9. 2009
    ..The aim of this questionnaire was to obtain an impression of the practice and applied therapeutic agents in postoperative and adjuvant intravesical therapy of superficial bladder tumours...
  49. ncbi request reprint Impact of chemotherapy on male fertility
    M Schrader
    Department of Urology, University Hospital Benjamin Franklin, Free University of Berlin, Germany
    Onkologie 24:326-30. 2001
    ..Before patients undergo cytostatic therapy, cryopreservation of germ cells should thus be suggested or, in some cases, testicular extraction of spermatozoa...
  50. pmc Quantitative real-time RT-PCR of CD24 mRNA in the detection of prostate cancer
    M Schostak
    Department of Urology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Germany
    BMC Urol 6:7. 2006
    ..We tested the usefulness of real-time RT-PCR for specific and sensitive detection of CD24 transcripts as a supplementary measure for discriminating between malignant and benign lesions in prostatic tissues...
  51. ncbi request reprint Increased incidence of luteinizing hormone-releasing hormone receptor gene messenger RNA expression in hormone-refractory human prostate cancers
    B Straub
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Hindenburgdamm 30, D 12200 Berlin, Germany
    Clin Cancer Res 7:2340-3. 2001
    ..In addition to possible direct effects of LHRH agonists or antagonists demonstrated previously in vitro, it seems useful to apply targeted cytotoxic LHRH analogues or monoclonal antibodies...
  52. ncbi request reprint Quantification of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA in testicular tissue of infertile patients
    M Schrader
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Germany
    Asian J Androl 3:263-70. 2001
    ....
  53. ncbi request reprint Kinetic fluorescence RT-PCR is highly sensitive for detection of germ-cell-tumor-specific transcripts in peripheral blood
    M Schrader
    Department of Urology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, D 12200 Berlin, Germany
    Int J Mol Med 16:143-7. 2005
    ..With high specificity, its sensitivity is higher than that of the corresponding serum tumor marker (82.92% vs 48.72%)...
  54. ncbi request reprint mRNA expression profiles of methylated APAF-1 and DAPK-1 tumor suppressor genes uncover clear cell renal cell carcinomas with aggressive phenotype
    F Christoph
    Department of Urology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Urol 178:2655-9. 2007
    ..We determined the relation between promoter methylation and mRNA expression of the p53 target genes APAF-1 and DAPK-1 in 55 consecutive tumor and corresponding normal tissue samples...
  55. ncbi request reprint Telomerase activity in malignant and benign renal tumors
    M Muller
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Germany
    Eur Urol 35:249-55. 1999
    ..The detection of telomerase activity provides new knowledge regarding the biologic growth behavior of tumors and offers new diagnostic and therapeutic tools...
  56. ncbi request reprint Osteoporosis and mild metabolic acidosis in the rat after orchiectomy and their prevention: should prophylactic therapy be administered to patients with androgen deprivation?
    B Straub
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Berlin, Germany
    J Urol 165:1783-9. 2001
    ..We characterized androgen deprivation and its prophylaxis...
  57. ncbi request reprint DNA-based detection of prostate cancer in blood, urine, and ejaculates
    C Goessl
    Department of Urology, Klinikum Benjamin Franklin, Freie Universitat Berlin, Germany
    Ann N Y Acad Sci 945:51-8. 2001
    ....
  58. ncbi request reprint Optimizing open live-donor nephrectomy - long-term donor outcome
    M Schostak
    Department of Urology, Charite, Campus Benjamin Franklin, Univeritätsmedizin Berlin, Berlin, Germany
    Clin Transplant 18:301-5. 2004
    ..This retrospective study examines the perioperative pain and morbidity and long-term outcome of living kidney donors from 35 yr of experience at the University Hospital Benjamin Franklin of the Free University of Berlin...
  59. ncbi request reprint [New concept minimizes bleeding in radical retropubic prostatectomy]
    M Schostak
    Urologische Klinik und Poliklinik, Charite Campus Benjamin Franklin, Universitatsmedizin, Berlin
    Urologe A 44:1332-6. 2005
    ....
  60. ncbi request reprint Frequent epigenetic inactivation of p53 target genes in seminomatous and nonseminomatous germ cell tumors
    F Christoph
    Department of Urology, Charite, Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Cancer Lett 247:137-42. 2007
    ..Further studies will be necessary to determine whether the methylation level may be used as marker for risk estimation, especially in clinical stage I disease...
  61. doi request reprint [Testicular germ cell cancer : interdependence between guidelines and a second-opinion system]
    M Schrader
    Klinik für Urologie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Deutschland
    Urologe A 48:393-8. 2009
    ..The results of the SOC system show that on the basis of this system, guidelines can be better implemented; in turn, the discrepancy between evidence-based guidelines and the actual treatment administered can be diminished...
  62. doi request reprint [New biomarkers and application of multivariate models for detection of prostate cancer]
    C Stephan
    Klinik für Urologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Aktuelle Urol 40:221-30. 2009
    ..There is generally an advantage to include the new markers and clinical data as additional parameters to PSA and %fPSA within ANN and LR models. Results of these studies and also unexpected pitfalls are discussed in this review...
  63. doi request reprint [What is most important is what comes across : Urological guidelines from the target group's point of view]
    J Busch
    Klinik für Urologie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Deutschland
    Urologe A 49:75-80. 2010
    ..The effect of German urologic guidelines has not been evaluated so far. Therefore, we aimed to systematically investigate the acceptance, use, and quality of the published guidelines from a user's perspective...
  64. doi request reprint Impact of obstructive interval and sperm granuloma on patency and pregnancy after vasectomy reversal
    A Magheli
    Department of Urology, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Int J Androl 33:730-5. 2010
    ..However, when counselling patients and their female partners, it is of utmost importance to stress that the age of the female partner is an independent predictor of successful vasectomy reversal...
  65. ncbi request reprint Comparison of human telomerase RNA and telomerase activity in urine for diagnosis of bladder cancer
    M Muller
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Germany
    Clin Cancer Res 4:1949-54. 1998
    ..Low hTR expression levels were found in 15% of the healthy controls. The detection of hTR by RT-PCR represents a promising new method for detecting malignant cells in urine...
  66. ncbi request reprint Concomitment spread of a renal cell carcinoma beyond the kidney and a transitional cell carcinoma beyond the bladder
    B Straub
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Germany
    Int Urol Nephrol 32:249-50. 2000
    ..A combination of the two diseases described here is obviously a remarkable rarity...
  67. doi request reprint [Evaluation of obstructive interval, presence of sperm granulomas and patient age as predictors of spermatogenesis in a cohort of men undergoing vasectomy reversal]
    A Magheli
    Abteilung für Urologie, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, Berlin
    Aktuelle Urol 41:52-7. 2010
    ..Thus far there is little knowledge about potential histological changes of the testis caused by vasectomy...
  68. ncbi request reprint Evaluation of urinary bladder cancer antigen as a marker for diagnosis of transitional cell carcinoma of the urinary bladder
    R Heicappell
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat, Berlin, Germany
    Scand J Clin Lab Invest 60:275-82. 2000
    ..6% (pTa) and 75% (pT4). Overall specificity was 76.6%. Based on our data we conclude that the UBC antigen test in its current format is not clinically useful for detection of bladder cancer...
  69. ncbi request reprint Living donor nephrectomy in an open technique; a long-term analysis of donor outcome
    M Schostak
    Department of Urology, Charite Universitatsmedizin Berlin Campus Benjamin Franklin, Berlin, Germany
    Transplant Proc 35:2096-8. 2003
  70. ncbi request reprint "Onco-tese": testicular sperm extraction in azoospermic cancer patients before chemotherapy-new guidelines?
    M Schrader
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Berlin, Germany
    Urology 61:421-5. 2003
    ..High-dose cytostatic therapy may be expected to cause long-term infertility. Thus, the standard procedure for fertility protection is cryopreservation of ejaculated spermatozoa before therapy...
  71. ncbi request reprint Microsatellite analysis of plasma DNA from patients with clear cell renal carcinoma
    C Goessl
    Department of Urology, Klinikum Benjamin Franklin, Freie Universitat Berlin, Germany
    Cancer Res 58:4728-32. 1998
    ..Analysis of plasma DNA from patients with clear cell renal carcinoma reveals tumor-specific microsatellite alterations and may therefore have diagnostic potential as a molecular tumor marker...
  72. ncbi request reprint [Improvements in surgical therapy of incontinence--failed outcome!]
    M Schostak
    Urologische Klinik und Poliklinik, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Hindenburgdamm 30, 12200 Berlin
    Urologe A 40:287-91. 2001
    ..The morbidity is unacceptable, especially when synthetic material is used in combination with bone anchors. Impaired vaginal wound healing often occurs in conjunction with irritative symptoms...
  73. ncbi request reprint Side effects of chemotherapy for advanced urothelial carcinoma with etoposide and ifosfamide
    M Muller
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Germany
    Urol Int 59:248-51. 1997
    ..In the present study, therefore, patients with advanced urothelial carcinoma and minor compromised renal function received combination chemotherapy with etoposide and ifosfamide...
  74. ncbi request reprint [Molecular diagnostics in urologic oncology. Detection of nucleic acids in urine samples]
    M Muller
    Urologische Klinik und Poliklinik, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin
    Urologe A 42:660-8. 2003
    ..The diagnostic application of these methods, however, remains in an experimental stage and must still clear several hurdles before becoming available for routine clinical use...
  75. ncbi request reprint Prostate cancer metastatic to the stomach
    F Christoph
    Department of Urology, University Hospital Benjamin Franklin, Free University of Berlin, Berlin, Germany
    Urology 63:778-9. 2004
    ..Computed tomography and bone scan revealed retroperitoneal lymphadenopathy and bone metastasis. Cranial computed tomography was negative for metastasis but upper endoscopy and biopsy revealed a metastatic lesion from prostate cancer...
  76. ncbi request reprint Photodynamic effects of sulfonated aluminum chlorophthalocyanine in human urinary bladder carcinoma cells in vitro
    M Muller
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat, Berlin, Germany
    Eur Urol 32:339-43. 1997
    ..The objective of the present study was to investigate the photodynamic effects of sulfonated aluminum chlorophthalocyanine on human bladder carcinoma cells...
  77. ncbi request reprint The impact of chemotherapy on male fertility: a survey of the biologic basis and clinical aspects
    M Schrader
    Department of Urology, University Hospital Benjamin Franklin, Free University of Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
    Reprod Toxicol 15:611-7. 2001
    ..Cryopreservation of germ cells can be suggested to patients undergoing cytostatic therapy. In some cases, testicular extraction of spermatozoa can also be offered as a novel approach...
  78. ncbi request reprint Shared decision-making--results from an interdisciplinary consulting service for prostate cancer
    M Schostak
    Department of Urology, Charite Campus Benjamin Franklin, Universitatsmedizin Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
    World J Urol 22:441-8. 2004
    ..In this study, patients chose either radical surgery or radiotherapy with equal frequency...
  79. doi request reprint Hormone therapy for prostate cancer - immediate initiation
    M Schostak
    Department of Urology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Front Radiat Ther Oncol 41:49-57. 2008
    ..This management can prevent prostate cancer from migrating to the bones, where treatment becomes extremely difficult and cure or even longterm control of the disease is an exception...
  80. ncbi request reprint T1G3 bladder cancer--the case for TUR and BCG
    K Miller
    Department of Urology, University Medical Center Benjamin Franklin, Berlin, Germany
    Front Radiat Ther Oncol 36:147-50. 2002
  81. ncbi request reprint Renal cell carcinoma in a kidney transplant: allogeneic genome in the tumor justifies organ-preserving surgery
    M Schostak
    Department of Urology, University Hospital Benjamin Franklin, Berlin, Germany
    Transplant Proc 34:2231-2. 2002
  82. ncbi request reprint [Molecular translational research--a juxtaposition of international developments and personal research approaches]
    H Krause
    Urologische Klinik und Hochschulambulanz, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindeburgdamm 30, 12200 Berlin
    Urologe A 46:1163-5. 2007
  83. ncbi request reprint How septic is urosepsis? Clinical course of infected hydronephrosis and therapeutic strategies
    F Christoph
    Department of Urology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    World J Urol 23:243-7. 2005
    ..Further research is necessary to provide conclusive evidence of the value of other early prognostic markers in patients with infected hydronephrosis...
  84. ncbi request reprint Long-term efficacy of tolterodine and patient compliance in pediatric patients with neurogenic detrusor overactivity
    F Christoph
    Department of Urology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Urol Int 79:55-9. 2007
    ..We investigated the effects of standard oral anticholinergic treatment with tolterodine in children with neurogenic bladder over a 5-year follow-up period and focused on treatment satisfaction, patient compliance and urodynamic parameters...
  85. ncbi request reprint [AUO Urogenital Cancer Studies]
    D Rohde
    Urologische Klinik, UKA, Aachen, Deutschland
    Onkologie 26:35-42. 2003
    ..auo-online.de) - with 18 open studies presented in the paper - but also serves as the principal driving force for interdisciplinary urogenital cancer networks and international intergroup activities (AUO/EORTC)...
  86. ncbi request reprint Acute scrotum due to arterial bleeding mimicking non-seminomatous germ cell tumor
    F Christoph
    Department of Urology, Charite Universitatsmedizin Berlin Campus Benjamin Franklin, Germany
    Asian J Androl 6:379-81. 2004
    ..Surgical exploration of the right testis by inguinal approach was performed revealing subcapsular arterial bleeding due to a small nonseminomatous germ cell tumor non-palpable on clinical examination...
  87. ncbi request reprint [Prostate biopsy -- practical examination of the adequacy of Chen's virtual strategy]
    M Schostak
    Urologische Klinik und Poliklinik der Charité Campus Benjamin Franklin, Universitatsmedizin Berlin
    Aktuelle Urol 36:149-53. 2005
    ..Chen et al. found ten "ideal" biopsy sites using a computer model. This study examines the clinical value of this variation of number and localisation of biopsies...
  88. ncbi request reprint [New polymorphisms in the PSA promoter in patients with prostate carcinoma]
    M Schostak
    Urologische Klinik und Hochschulambulanz der Charité Universitätsmedizin Berlin
    Aktuelle Urol 38:465-72. 2007
    ..We searched for single nucleotide polymorphisms (SNP) in four different parts of the PSA promoter, which harbour binding sites for major transcriptional regulators using PCR-based combined SSCP and sequence analysis...
  89. doi request reprint Radical prostatectomy in the 21st century - the gold standard for localized and locally advanced prostate cancer
    M Schostak
    Department of Urology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Front Radiat Ther Oncol 41:7-14. 2008
    ..Pathological staging enables stratified adjuvant therapy based on concrete information. The overall prognosis can thus be significantly improved...
  90. doi request reprint [Expression levels of the IAP antagonists XAF1, Smac/DIABLO and HtrA2 in testicular germ cell tumours]
    C Kempkensteffen
    Charité Universitätsmedizin Berlin Campus Mitte, Abteilung für Urologie, Berlin
    Aktuelle Urol 39:436-41. 2008
    ..We examined the mRNA-expression of these pro-apoptotic parameters in testicular germ cell tumors (TGCT) and normal testicular tissue and correlated their expression levels to clinicopathological tumour features...
  91. doi request reprint [Germ cell tumors - documentation of diagnosis and therapy by means of a web-based modular database system]
    N Schreiter
    Die Institutsangaben sind am Ende des Beitrags gelistet
    Aktuelle Urol 39:442-7. 2008
    ..The aim of this study was to develop an internet platform to document the quality of individual sections of treatment for patients with germ cell tumours in Berlin and to improve the therapy in conformity with the S2 guidelines...
  92. doi request reprint [New developments in minimally invasive urology: NOTES (Natural Orifice Transluminal Endoscopic Surgery) and LESS (Laparo-Endoscopic Single-Site Surgery) in urology]
    S Deger
    Klinik und Poliklinik für Urologie der Charité, Universitatsmedizin Berlin, Berlin
    Aktuelle Urol 40:23-6. 2009
    ..In the next few years, comparative studies between these techniques and conventional laparoscopy can be expected...
  93. doi request reprint [Incarcerated hernia after laparoscopic drainage of a lymphocele]
    F Friedersdorff
    Klinik für Urologie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Deutschland
    Urologe A 49:1169-71. 2010
    ..CT imaging and swift reoperation with enlargement of the peritoneal window are critical to avoid serious complications. To avoid bowel incarceration, the peritoneal window should be as large as possible...
  94. doi request reprint Outcome of treatment discontinuation in patients with metastatic renal cell carcinoma and no evidence of disease following targeted therapy with or without metastasectomy
    M Johannsen
    Department of Urology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Ann Oncol 22:657-63. 2011
    ....
  95. doi request reprint [Urogynaecology for urologists]
    J Neymeyer
    Klinik für Urologie und Urologische Hochschulambulanz, Charite Universitatsmedizin Berlin, Germany
    Aktuelle Urol 42:233-41. 2011
    ..Other foci are urinary infections, chronic pelvic pain as well as postoperative and posttraumatic insufficiency of the pelvic floor...
  96. ncbi request reprint Quantification of the expression level of the gene encoding the catalytic subunit of telomerase in testicular tissue specimens predicts successful sperm recovery
    M Schrader
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
    Hum Reprod 17:150-6. 2002
    ..This was paralleled by conventional histological work-up in all tissue specimens and additional semithin sectioning preparation in cases with maturation arrest (n = 20) and Sertoli cell-only syndrome (SCOS; n = 12)...
  97. ncbi request reprint Optimizing local anesthesia during 10-core biopsy of the prostate
    M Schostak
    Department of Urology, University Hospital Benjamin Franklin, Freie Universitat, Berlin, Germany
    Urology 60:253-7. 2002
    ..Reports thus far have shown a high variability in assessing the pain intensity of prostate biopsies and the effectiveness of anesthesia...
  98. ncbi request reprint Quantification of telomerase activity, porphobilinogen deaminase and human telomerase reverse transcriptase mRNA in testicular tissue - new parameters for a molecular diagnostic classification of spermatogenesis disorders
    M Schrader
    Department of Urology, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Berlin, Germany
    Int J Androl 25:34-44. 2002
    ....
  99. ncbi request reprint Long-term follow-up after open perineal cryotherapy in patients with locally confined prostate cancer
    D Mack
    Department of Urology, Salzburg General Hospital, Austria
    Eur Urol 32:129-32. 1997
    ..CONCLUSIONS: Cryosurgery is an effective treatment for locally confined prostate cancer. With improvement of the procedure, clinical outcome may also improve...
  100. ncbi request reprint A comparison of basal cell markers used in the prostate
    A Freeman
    Histopathology 40:492-4. 2002
  101. pmc HER-2/neu expression in germ cell tumours
    S Soule
    Division of Hematology and Oncology, Indiana University School of Medicine, Indianapolis 46202, USA
    J Clin Pathol 55:656-8. 2002
    ..To determine the rate of HER-2/neu positivity of germ cell tumours by immunohistochemistry (IHC) and by fluorescence in situ hybridisation (FISH)...