Ralph Kettritz

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint [Iatrogenic electrolyte disorders]
    R Kettritz
    Nephrologie und internistische Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Deutschland
    Internist (Berl) 56:745-52. 2015
  2. doi request reprint The neutrophil in antineutrophil cytoplasmic autoantibody-associated vasculitis
    Adrian Schreiber
    1 Virchow Klinikum Campus and Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and the Charité Medical Faculty, Lindenberger Weg 80, 13125 Berlin, Germany
    J Leukoc Biol 94:623-31. 2013
  3. pmc How anti-neutrophil cytoplasmic autoantibodies activate neutrophils
    R Kettritz
    Nephrologie und Internistische Intensivmedizin Charité Virchow Klinikum and Experimental and Clinical Research Center, a joint co operation between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, Berlin Buch, Berlin, Germany
    Clin Exp Immunol 169:220-8. 2012
  4. doi request reprint Genotypic testing in clinically defined HHT: would Osler approve or turn in his grave?
    R Kettritz
    Nephrology Department and Experimental and Clinical Research Center, Faculty of Charite and Max Delbrück Center for Molecular Medicine, Berlin, Germany
    J R Coll Physicians Edinb 42:128-30. 2012
  5. doi request reprint Autoimmunity in kidney diseases
    Ralph Kettritz
    Medical Faculty of the Charite, Experimental and Clinical Research Center, Franz Volhard Clinic at the Max Delbruck Center, HELIOS Klinikum Berlin, Germany
    Scand J Clin Lab Invest Suppl 241:99-103. 2008
  6. ncbi request reprint The protean face of sarcoidosis revisited
    Ralph Kettritz
    Franz Volhard Clinic, Wiltbergstrasse 50, 13122 Berlin, FRG
    Nephrol Dial Transplant 21:2690-4. 2006
  7. ncbi request reprint Fever-like temperatures affect neutrophil NF-kappaB signaling, apoptosis, and ANCA-antigen expression
    Ralph Kettritz
    Medical Faculty of the Charite, Department of Nephrology and Hypertension, Franz Volhard Clinic at the Max Delbrück Center for Molecular Medicine, HELIOS Klinikum Berlin, Berlin, Germany
    J Am Soc Nephrol 17:1345-53. 2006
  8. pmc Short-term heat exposure inhibits inflammation by abrogating recruitment of and nuclear factor-{kappa}B activation in neutrophils exposed to chemotactic cytokines
    Mira Choi
    Helios Klinikum Berlin Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany
    Am J Pathol 172:367-777. 2008
  9. ncbi request reprint The effect of fever-like temperatures on neutrophil signaling
    Birgit Salanova
    Medical Faculty of the Charite, Department of Nephrology and Hypertension, Franz Volhard Clinic at the Max Delbrück Center for Molecular Medicine, HELIOS Klinikum Berlin, Germany
    FASEB J 19:816-8. 2005
  10. doi request reprint Aldosterone abrogates nuclear factor kappaB-mediated tumor necrosis factor alpha production in human neutrophils via the mineralocorticoid receptor
    Astrid Bergmann
    Medical Faculty of the Charite, Department of Nephrology and Hypertension, Franz Volhard Clinic, HELIOS Klinikum Berlin, Experimental and Clinical Research Center at the Max Delbrück Center for Molecular Medicine, Berlin, Germany
    Hypertension 55:370-9. 2010

Collaborators

Detail Information

Publications53

  1. doi request reprint [Iatrogenic electrolyte disorders]
    R Kettritz
    Nephrologie und internistische Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Deutschland
    Internist (Berl) 56:745-52. 2015
    ..These case reports illustrate common, but also rare iatrogenic situations. The discussion of these cases is aimed at raising awareness of the issues involved in a pathophysiological approach to clinical problems. ..
  2. doi request reprint The neutrophil in antineutrophil cytoplasmic autoantibody-associated vasculitis
    Adrian Schreiber
    1 Virchow Klinikum Campus and Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and the Charité Medical Faculty, Lindenberger Weg 80, 13125 Berlin, Germany
    J Leukoc Biol 94:623-31. 2013
    ..We not only discuss the significance of ANCA-neutrophil interactions for disease induction but also how a detailed understanding of these interactions helps to identify novel treatment targets for ANCA vasculitis. ..
  3. pmc How anti-neutrophil cytoplasmic autoantibodies activate neutrophils
    R Kettritz
    Nephrologie und Internistische Intensivmedizin Charité Virchow Klinikum and Experimental and Clinical Research Center, a joint co operation between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, Berlin Buch, Berlin, Germany
    Clin Exp Immunol 169:220-8. 2012
    ....
  4. doi request reprint Genotypic testing in clinically defined HHT: would Osler approve or turn in his grave?
    R Kettritz
    Nephrology Department and Experimental and Clinical Research Center, Faculty of Charite and Max Delbrück Center for Molecular Medicine, Berlin, Germany
    J R Coll Physicians Edinb 42:128-30. 2012
    ..Would he have required or supported genetic testing? We treated a patient whose case reminded us of Sir William's belief that clinical exactness was the ultimate aim, regardless of cost...
  5. doi request reprint Autoimmunity in kidney diseases
    Ralph Kettritz
    Medical Faculty of the Charite, Experimental and Clinical Research Center, Franz Volhard Clinic at the Max Delbruck Center, HELIOS Klinikum Berlin, Germany
    Scand J Clin Lab Invest Suppl 241:99-103. 2008
    ..Better understanding of the PR3-NB1 interaction may have therapeutic implications with the development of more selective drugs...
  6. ncbi request reprint The protean face of sarcoidosis revisited
    Ralph Kettritz
    Franz Volhard Clinic, Wiltbergstrasse 50, 13122 Berlin, FRG
    Nephrol Dial Transplant 21:2690-4. 2006
  7. ncbi request reprint Fever-like temperatures affect neutrophil NF-kappaB signaling, apoptosis, and ANCA-antigen expression
    Ralph Kettritz
    Medical Faculty of the Charite, Department of Nephrology and Hypertension, Franz Volhard Clinic at the Max Delbrück Center for Molecular Medicine, HELIOS Klinikum Berlin, Berlin, Germany
    J Am Soc Nephrol 17:1345-53. 2006
    ..These data suggest that fever-like temperatures modulate neutrophil behavior in this disease...
  8. pmc Short-term heat exposure inhibits inflammation by abrogating recruitment of and nuclear factor-{kappa}B activation in neutrophils exposed to chemotactic cytokines
    Mira Choi
    Helios Klinikum Berlin Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany
    Am J Pathol 172:367-777. 2008
    ..These new findings suggest that heat may have anti-inflammatory effects in neutrophil-dependent inflammation...
  9. ncbi request reprint The effect of fever-like temperatures on neutrophil signaling
    Birgit Salanova
    Medical Faculty of the Charite, Department of Nephrology and Hypertension, Franz Volhard Clinic at the Max Delbrück Center for Molecular Medicine, HELIOS Klinikum Berlin, Germany
    FASEB J 19:816-8. 2005
    ..The effect could protect circulating neutrophils from TNF-alpha activation, while not interfering with activation of adherent neutrophils. Fever could make neutrophils more parsimonious...
  10. doi request reprint Aldosterone abrogates nuclear factor kappaB-mediated tumor necrosis factor alpha production in human neutrophils via the mineralocorticoid receptor
    Astrid Bergmann
    Medical Faculty of the Charite, Department of Nephrology and Hypertension, Franz Volhard Clinic, HELIOS Klinikum Berlin, Experimental and Clinical Research Center at the Max Delbrück Center for Molecular Medicine, Berlin, Germany
    Hypertension 55:370-9. 2010
    ..Our data indicate that a functional MR exists in neutrophils mediating antiinflammatory effects that are at work when neutrophils interact with endothelial cells. These data could be relevant to MR-blockade treatment protocols...
  11. doi request reprint Phosphoinositol 3-kinase-gamma mediates antineutrophil cytoplasmic autoantibody-induced glomerulonephritis
    Adrian Schreiber
    Department of Nephrology and Hypertension, Medical Faculty of the Charite, Franz Volhard Clinic, Max Delbruck Center for Molecular Medicine, Schwanebecker Chaussee 50, Berlin, Germany
    Kidney Int 77:118-28. 2010
    ..We found that PI3Kgamma plays a pivotal role in ANCA-induced NCGN and suggest that its specific inhibition may provide a novel treatment target...
  12. ncbi request reprint Febrile temperatures control antineutrophil cytoplasmic autoantibody-induced neutrophil activation via inhibition of phosphatidylinositol 3-kinase/Akt
    Sibylle von Vietinghoff
    Franz Volhard Klinik, Berlin, Germany
    Arthritis Rheum 56:3149-58. 2007
    ..Heat exposure may affect the underlying pathophysiologic processes of the vasculitis. In this study we tested the hypothesis that short-term exposure to heat inhibits ANCA-induced neutrophil activation...
  13. pmc Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation
    Uwe Jerke
    Medical Faculty of the Charite, Experimental and Clinical Research Center, Berlin, Germany
    J Biol Chem 286:7070-81. 2011
    ..We establish the pivotal role of the NB1-Mac-1 receptor interaction for PR3-ANCA-mediated neutrophil activation...
  14. pmc C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis
    Adrian Schreiber
    Medical Faculty of the Charite, Department of Nephrology and Hypertension, Franz Volhard Clinic at the Max Delbrück Center for Molecular Medicine, HELIOS Klinikum Berlin, Berlin, Germany
    J Am Soc Nephrol 20:289-98. 2009
    ..05). In summary, C5a and the neutrophil C5aR may compose an amplification loop for ANCA-mediated neutrophil activation. The C5aR may provide a new therapeutic target for ANCA-induced necrotizing crescentic glomerulonephritis...
  15. pmc β2 integrin-mediated cell-cell contact transfers active myeloperoxidase from neutrophils to endothelial cells
    Uwe Jerke
    Experimental and Clinical Research Center, Charité Medical Faculty, Berlin, Germany
    J Biol Chem 288:12910-9. 2013
    ..The data suggest an alternative to EC uptake of soluble MPO, namely the cell contact-dependent, β2 integrin-mediated transfer from neutrophils. The findings could be of therapeutic relevance in atherosclerosis and vasculitis...
  16. ncbi request reprint Membrane proteinase 3 expression and ANCA-induced neutrophil activation
    Adrian Schreiber
    HELIOS Klinikum Berlin, Franz Volhard Clinic, and Max Delbruck Center for Molecular Medicine, Medical Faculty of the Charite, Humboldt University of Berlin, Germany
    Kidney Int 65:2172-83. 2004
    ....
  17. ncbi request reprint Beta2-integrins and acquired glycoprotein IIb/IIIa (GPIIb/IIIa) receptors cooperate in NF-kappaB activation of human neutrophils
    Birgit Salanova
    Franz Volhard Clinic and Max Delbrueck Center for Molecular Medicine, Medical Faculty of the Charite, HELIOS Kliniken, 13125 Berlin, Germany
    J Biol Chem 282:27960-9. 2007
    ..The compounds also inhibited NF-kappaB-dependent tumor necrosis factor-alpha mRNA up-regulation. The data implicate GPIIb/IIIa receptors as new therapeutic targets in neutrophil-induced inflammation...
  18. pmc BK channels in innate immune functions of neutrophils and macrophages
    Kirill Essin
    Department of Nephrology, Campus Virchow, Medical Faculty of the Charite, Experimental and Clinical Research Center at the Max Delbrück Center for Molecular Medicine, Berlin, Germany
    Blood 113:1326-31. 2009
    ..Based on these data, we conclude that the BK channel is not required for NADPH oxidase activity in PMNs or macrophages or for endotoxin-triggered tumor necrosis factor-alpha release and signal transduction BMDMs...
  19. ncbi request reprint Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA
    Mira Choi
    HELIOS Klinkum Berlin Franz Volhard Clinic and Max Delbrück Center for Molecular Medicine, Medical Faculty of the Charite, Humboldt University of Berlin, Berlin, Germany
    Kidney Int 63:96-106. 2003
    ..We tested the hypothesis that statins decrease respiratory burst activity of human polymorphonuclear neutrophils (PMN) in response to anti-neutrophil cytoplasmic antibodies (ANCA)...
  20. ncbi request reprint Integrins and cytokines activate nuclear transcription factor-kappaB in human neutrophils
    Ralph Kettritz
    Medical Faculty of the Charite, Department of Nephrology and Hypertension, Franz Volhard Clinic, Helios Klinikum Berlin and Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany
    J Biol Chem 279:2657-65. 2004
    ..This effect may become important when human neutrophils leave the circulating blood and migrate through extracellular matrix during inflammation...
  21. ncbi request reprint Phosphatidylinositol 3-kinase controls antineutrophil cytoplasmic antibodies-induced respiratory burst in human neutrophils
    Ralph Kettritz
    HELIOS Klinikum Berlin, Franz Volhard Clinic, Medical Faculty of the Charite, Humboldt University of Berlin, Wiltbergstrasse 50, 13122 Berlin, Germany
    J Am Soc Nephrol 13:1740-9. 2002
    ..TNF-alpha stimulation increased association of PAK1 with Akt. An MPO monoclonal antibody did not alter the Akt signaling complex further. The data demonstrate the importance of PI3-K for the ANCA-induced PMN oxidant production...
  22. pmc Myeloperoxidase-specific plasma cell depletion by bortezomib protects from anti-neutrophil cytoplasmic autoantibodies-induced glomerulonephritis
    Julia Bontscho
    Experimental and Clinical Research Center at the Charité and Max Delbrück Center for Molecular Medicine, Lindenberger Weg 80, 13125 Berlin, Germany
    J Am Soc Nephrol 22:336-48. 2011
    ..Three of 23 BTZ-treated mice died within 36 hours after BTZ administration. In summary, BTZ depletes MPO-specific plasma cells, reduces anti-MPO titers, and prevents NCGN in mice...
  23. pmc Neutrophil serine proteases promote IL-1β generation and injury in necrotizing crescentic glomerulonephritis
    Adrian Schreiber
    Max Delbruck Center for Molecular Medicine, Charite Berlin, Berlin, Germany
    J Am Soc Nephrol 23:470-82. 2012
    ..These data suggest that the development of anti-MPO antibody-induced NCGN requires NSP-dependent IL-1β generation and that these processes may provide therapeutic targets for ANCA-mediated diseases in humans...
  24. ncbi request reprint Membrane proteinase 3 expression in patients with Wegener's granulomatosis and in human hematopoietic stem cell-derived neutrophils
    Adrian Schreiber
    HELIOS Klinikum Berlin, Franz Volhard Clinic and Max Delbrück Center for Molecular Medicine, Medical Faculty of the Charite, Humboldt University of Berlin, Berlin, Germany
    J Am Soc Nephrol 16:2216-24. 2005
    ..Taken together, these studies underscore the clinical importance of the WG mPR3 phenotype. The surface mPR3 on resting cells is probably genetically determined rather than being dictated by external factors...
  25. ncbi request reprint Inhibition of NF-kappaB by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis
    Mira Choi
    Division of Nephrology, Franz Volhard Clinic, Medical Faculty of the Charite, Humboldt Univertsity of Berlin, Wiltbergstrasse 50, 13122 Berlin, Germany
    Blood 102:2259-67. 2003
    ..This strategy may help in controlling various cellular functions even in short-lived, transfection-resistant primary human cells...
  26. ncbi request reprint NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils
    Sibylle von Vietinghoff
    Franz Volhard Clinic, Department of Nephrology and Hypertension, Medical Faculty of the Charite, HELIOS Klinikum, Berlin, Germany
    Blood 109:4487-93. 2007
    ..Transfection with NB1 resulted in specific PR3 surface binding in different cell types. We conclude that PR3 membrane expression on neutrophils is mediated by the NB1 receptor...
  27. pmc Urinary neutrophil gelatinase-associated lipocalin distinguishes pre-renal from intrinsic renal failure and predicts outcomes
    Eugenia Singer
    Experimental and Clinical Research Center, a joint institution of the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, Berlin, Germany
    Kidney Int 80:405-14. 2011
    ..Hence, urinary NGAL is useful in classifying and stratifying patients with established AKI...
  28. ncbi request reprint Pseudo-pseudo Meigs' syndrome
    Roland Schmitt
    Medical Faculty of the Charite, Franz Volhard Clinic, Wiltberg Strasse 50, 13125 Berlin, Germany
    Lancet 366:1672. 2005
  29. ncbi request reprint Membrane expression of proteinase 3 is genetically determined
    Adrian Schreiber
    HELIOS Klinikum Berlin, Franz Volhard Clinic and Max Delbrück Center for Molecular Medicine, Medical Faculty of the Charite, Humboldt University of Berlin, Germany
    J Am Soc Nephrol 14:68-75. 2003
    ..These data indicate that WG patients have a higher percentage of mPR3-expressing neutrophils. Furthermore, mPR3 expression is influenced by genetic variance. Finally, mPR3 expression is independent of intracellular PR3 content...
  30. pmc Posttransplantation malignancy in a patient presenting with weight loss and changed bowel habits: a case report
    Roland Schmitt
    Medical Faculty of the Charite, Franz Volhard Clinic, HELIOS Klinikum Berlin, Germany
    BMC Nephrol 7:9. 2006
    ..Advancements in immunosuppressive therapy have significantly improved patient and graft survival following renal transplantation. This is paralleled by an increasing occurrence of posttransplantation malignancy...
  31. ncbi request reprint Lactate in a laubenpieper
    Wolfgang Derer
    Medical Faculty of the Charite, Intensive Care Unit, Franz Volhard Clinic, HELIOS Klinikum Berlin, Germany
    Nephrol Dial Transplant 20:2851-4. 2005
    ..Acid-base disorders seldom kill; however, the mechanisms and associated complications certainly do. We recently encountered a patient with a mysterious lactic acidosis. The patient proved to be a most capable teacher of important lessons...
  32. ncbi request reprint A 77 year-old haemodialysis patient with unexpected alkalosis
    Sibylle von Vietinghoff
    Medical Faculty of the Charite, HELIOS Klinikum, Berlin, Germany
    Nephrol Dial Transplant 20:2569-70. 2005
  33. ncbi request reprint Major histocompatibility complex HLA region largely explains the genetic variance exercised on neutrophil membrane proteinase 3 expression
    Sibylle von Vietinghoff
    Medical Faculty of the Charite, Department of Nephrology and Hypertension, Franz Volhard Clinic, HELIOS Klinikum Berlin, Max Delbrück Center for Molecular Medicine Campus Buch, Germany
    J Am Soc Nephrol 17:3185-91. 2006
    ..001). The data suggest that a complex interaction of the entire HLA system is responsible for the genetic influence on membrane PR3 percentage and Wegener's granulomatosis...
  34. ncbi request reprint Lessons from a double-transgenic neutrophil approach to induce antiproteinase 3 antibody-mediated vasculitis in mice
    Adrian Schreiber
    Experimental and Clinical Research Center, Charite, Universitatsmedizin Berlin, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany
    J Leukoc Biol 100:1443-1452. 2016
    ..We conclude that important species differences in PR3 and CD177 exist between men and mice that prevented successful generation of a murine anti-PR3 antibody model...
  35. doi request reprint Cardiovascular magnetic resonance imaging detects cardiac involvement in Churg-Strauss syndrome
    Ralf Wassmuth
    Cardiology Department, Franz Volhard Klinik, Charite Campus Buch, and HELIOS Klinikum Berlin, Berlin, Germany
    J Card Fail 14:856-60. 2008
    ..We tested whether CMR could elucidate cardiac damage in patients with biopsy-proven Churg-Strauss syndrome and clinical evidence of cardiac involvement...
  36. ncbi request reprint TNF-alpha--accelerated apoptosis abrogates ANCA-mediated neutrophil respiratory burst by a caspase-dependent mechanism
    Ralph Kettritz
    HELIOS Klinikum Berlin, Franz Volhard Clinic, and Max Delbruck Center for Molecular Medicine, Medical Faculty of the Charite, Humboldt University of Berlin, Germany
    Kidney Int 61:502-15. 2002
    ..TNF-alpha also progressively accelerates apoptosis. We investigated the effect of TNF-alpha-mediated apoptosis on ANCA antigen expression and on ANCA-induced superoxide generation in human PMN...
  37. doi request reprint Simultaneous chemoradiation with cisplatin in a patient with recurrent cervical cancer undergoing hemodialysis: analysis of cisplatin concentrations in serum and dialysate and therapy-related acute toxicity
    Simone Marnitz
    Department of Radiooncology, Charite University Medicine, Berlin, Germany
    Strahlenther Onkol 187:831-4. 2011
    ..To prove the feasibility and toxicity of platinum-based chemoradiation in a patient with recurrent cervical cancer undergoing concomitant hemodialysis...
  38. ncbi request reprint Niacin lowers serum phosphate and increases HDL cholesterol in dialysis patients
    Daniela Muller
    Franz Volhard Clinic, Department of Nephrology and Hypertension, Medical Faculty of the Charite, HELIOS Klinikum Berlin, Berlin, Germany
    Clin J Am Soc Nephrol 2:1249-54. 2007
    ..Adverse effects complicate the use of drugs that are prescribed for phosphate control in dialysis patients. Alternative treatment options are needed...
  39. ncbi request reprint Crescentic glomerulonephritis and malignancy--guilty or guilt by association?
    Sibylle von Vietinghoff
    Medical Faculty of the Charite, Franz Volhard Clinic, Department of Pathology, HELIOS Klinikum Berlin, Wiltbergstrasse 50, 13122 Berlin, Germany
    Nephrol Dial Transplant 21:3324-6. 2006
  40. ncbi request reprint A particularly private pain
    Ursula Göbel
    Franz Volhard Clinic, First Department of Internal Medicine and Department of Pathology, Klinikum Buch Medical Faculty of the Charité Humbolt University of Berlin, Germany
    Nephrol Dial Transplant 17:516-8. 2002
  41. ncbi request reprint An expanding flank mass in an anephric patient
    Ute Kettritz
    Medical Faculty of the Charite, Franz Volhard Clinic, Berlin, Germany
    Am J Kidney Dis 44:930-6. 2004
  42. ncbi request reprint Thyroid function and glomerular filtration--a potential for Grave errors
    Theresa Claus
    Franz Volhard Clinic, Wiltbergstrasse 50, D 13125 Berlin, Germany
    Nephrol Dial Transplant 20:1002-3. 2005
  43. ncbi request reprint Where do we stand with renovascular hypertension?
    Theresa Claus
    Medical Faculty of the Charite, Franz Volhard Clinic, HELIOS Klinikum Berlin, Germany
    Nephrol Dial Transplant 20:1495-8. 2005
  44. doi request reprint Neutrophil serine proteases exert proteolytic activity on endothelial cells
    Uwe Jerke
    Experimental and Clinical Research Center, a joint cooperation between the Charité and the Max Delbrück Center for Molecular Medicine MDC, Berlin, Germany
    Kidney Int 88:764-75. 2015
    ..Thus, we identified novel NSP substrates and suggest NSP inhibition as a therapeutic measure to inhibit neutrophil-mediated inflammatory vascular diseases...
  45. pmc Phagocyte NADPH oxidase restrains the inflammasome in ANCA-induced GN
    Adrian Schreiber
    Experimental and Clinical Research Center at the Max Delbrueck Centrum Berlin and Campus Virchow Clinic, Medical Faculty of the Charite, Department of Nephrology and Intensive Care Medicine, Charite Berlin, Berlin, Germany
    J Am Soc Nephrol 26:411-24. 2015
    ..IL-1 receptor blockade may provide a promising strategy in NCGN, whereas our data question the benefit of antioxidants. ..
  46. ncbi request reprint Lumpy jaw revisited
    Sibylle von Vietinghoff
    Franz Volhard Clinic and Department of Radiology, HELIOS Klinikum, Berlin, Germany
    Nephrol Dial Transplant 20:837-9. 2005
  47. ncbi request reprint Differential expression of classical nuclear transport factors during cellular proliferation and differentiation
    Matthias Kohler
    HELIOS Clinic Franz Volhard Clinic at the Max Delbrueck Center, Medical Faculty of the Charite, Berlin, Germany
    Cell Physiol Biochem 12:335-44. 2002
    ..This study is the first to assess all the human importin alpha isoforms in documenting differential nuclear transport factor regulation during cell proliferation and differentiation...
  48. ncbi request reprint Not so acute renal failure with crystals in the urine
    Bastian Dehmel
    HELIOS Klinikum Berlin, Franz Volhard Clinic, Medical Faculty of the Charite, Humboldt University of Berlin, Germany
    Nephrol Dial Transplant 18:209-11. 2003
  49. ncbi request reprint Solving electrolyte disturbances with the Ehrlich reagent
    Adrian Schreiber
    HELIOS Klinikum Berlin, Franz Volhard Clinic, Berlin, Germany
    Nephrol Dial Transplant 18:1217-9. 2003
  50. ncbi request reprint Colchicum ad nauseum
    Andras Kumar
    Franz Volhard Clinic, Humbolt University of Berlin, Berlin, Germany
    Nephrol Dial Transplant 18:2197-8. 2003
  51. ncbi request reprint Adipose tissue metabolism and CD11b expression on monocytes in obese hypertensives
    Michael Boschmann
    Franz Volhard Clinical Research Center, Charite Campus Buch, HELIOS Klinikum, Berlin, Germany
    Hypertension 46:130-6. 2005
    ..These findings may be explained in part by monocyte/macrophage infiltration of adipose tissue, which appears to interfere with insulin responsiveness...
  52. ncbi request reprint Hard times with hard water
    Ralph Kettritz
    Franz Volhard Clinic, HELIOS Klinikum Berlin, Medical Faculty of the Charite, Humboldt University of Berlin, Berlin, Germany
    Nephrol Dial Transplant 19:1925-7. 2004
  53. ncbi request reprint Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity
    Kirill Essin
    Department of Nephrology and Medical Intensive Care, Charite University Medicine Berlin, Humboldt University of Berlin, Germany
    Am J Physiol Cell Physiol 293:C45-54. 2007
    ..In conclusion, our experiments failed to identify functional BK channels in neutrophils. We therefore conclude that BK channels are not essential for innate immunity...