Korinna Johrens

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint Three different expression patterns of T-bet in angioimmunoblastic T-cell lymphoma
    Korinna Johrens
    Institute of Pathology, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    Leuk Lymphoma 53:152-5. 2012
  2. ncbi request reprint T-bet transcription factor detection facilitates the diagnosis of minimal hairy cell leukemia infiltrates in bone marrow trephines
    Korinna Johrens
    Consultation and Reference Center for Hematopathology at the Institute of Pathology, Charite Campus Benjamin Franklin, Universitatsmedizin Berlin, Germany
    Am J Surg Pathol 31:1181-5. 2007
  3. doi request reprint Non-neoplastic TdT-positive cells in bone marrow trephines with acute myeloid leukaemia before and after treatment express myeloid molecules
    Korinna Johrens
    Institute of Pathology, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Pathobiology 78:35-40. 2011
  4. doi request reprint Interferon-gamma and T-bet expression in a patient with toxoplasmic lymphadenopathy
    Korinna Johrens
    Charite University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm, Berlin, Germany
    Hum Immunol 71:366-71. 2010
  5. doi request reprint T-box-expressed-in-T-cells (T-bet) expression by the tumor cells of hairy-cell leukemia correlates with interferon-gamma production
    Korinna Johrens
    Consultation and Reference Center for Hematopathology, Institute of Pathology, Charite University Medicine Berlin, Campus Benjamin Franklin, 12203 Berlin, Germany
    Leuk Lymphoma 50:1687-92. 2009
  6. doi request reprint A novel CD11c monoclonal antibody effective in formalin-fixed tissue for the diagnosis of hairy cell leukemia
    Korinna Johrens
    Institute of Pathology and Reference Center for Hematopathology, Charite, Medical University Berlin, Berlin, Germany
    Pathobiology 75:252-6. 2008
  7. doi request reprint Marginal zone lymphomas with monocytoid morphology express T-bet and are associated with a low number of T cells in extranodal locations
    Philipp Lohneis
    Institute of Pathology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Leuk Lymphoma 55:143-8. 2014
  8. doi request reprint Differences in the T-bet and GATA-3 expression patterns between lymphocytic colitis and coeliac disease
    Korinna Johrens
    Institute for Pathology, Charite, Campus Benjamin Franklin, Medical University Berlin, Berlin, Germany
    Virchows Arch 457:451-6. 2010
  9. ncbi request reprint Fibrosis in low-grade follicular lymphoma - a link to the TH2 immune reaction
    Philipp Lohneis
    a Institute of Pathology, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Leuk Lymphoma . 2016
  10. doi request reprint CT-guided radiofrequency ablation of osteoid osteoma using a novel battery-powered drill
    Dirk Schnapauff
    Department of Radiology, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Skeletal Radiol 44:695-701. 2015

Collaborators

Detail Information

Publications29

  1. doi request reprint Three different expression patterns of T-bet in angioimmunoblastic T-cell lymphoma
    Korinna Johrens
    Institute of Pathology, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    Leuk Lymphoma 53:152-5. 2012
    ....
  2. ncbi request reprint T-bet transcription factor detection facilitates the diagnosis of minimal hairy cell leukemia infiltrates in bone marrow trephines
    Korinna Johrens
    Consultation and Reference Center for Hematopathology at the Institute of Pathology, Charite Campus Benjamin Franklin, Universitatsmedizin Berlin, Germany
    Am J Surg Pathol 31:1181-5. 2007
    ..Therefore, the immunohistochemical detection of T-bet in infiltrated bone marrow trephines represents an important adjunct for the diagnosis of HCL...
  3. doi request reprint Non-neoplastic TdT-positive cells in bone marrow trephines with acute myeloid leukaemia before and after treatment express myeloid molecules
    Korinna Johrens
    Institute of Pathology, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Pathobiology 78:35-40. 2011
    ..During our routine bone marrow trephine analysis of patients with acute myeloid leukaemia (AML) before and after treatment, we observed the presence of TdT-positive cells lacking CD34, CD10 and B cell antigens...
  4. doi request reprint Interferon-gamma and T-bet expression in a patient with toxoplasmic lymphadenopathy
    Korinna Johrens
    Charite University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm, Berlin, Germany
    Hum Immunol 71:366-71. 2010
    ..We conclude that the pathogenesis and course of toxoplasmic lymphadenopathy is based on a T(h)1-cell defect, which becomes compensated by the B cells mounting a T(h)1-like immune response...
  5. doi request reprint T-box-expressed-in-T-cells (T-bet) expression by the tumor cells of hairy-cell leukemia correlates with interferon-gamma production
    Korinna Johrens
    Consultation and Reference Center for Hematopathology, Institute of Pathology, Charite University Medicine Berlin, Campus Benjamin Franklin, 12203 Berlin, Germany
    Leuk Lymphoma 50:1687-92. 2009
    ....
  6. doi request reprint A novel CD11c monoclonal antibody effective in formalin-fixed tissue for the diagnosis of hairy cell leukemia
    Korinna Johrens
    Institute of Pathology and Reference Center for Hematopathology, Charite, Medical University Berlin, Berlin, Germany
    Pathobiology 75:252-6. 2008
    ..In this study, we assessed the utility of a newly developed antibody against a formalin-resistant CD11c epitope (5D11) for the diagnosis and monitoring of HCL in formalin-fixed tissue...
  7. doi request reprint Marginal zone lymphomas with monocytoid morphology express T-bet and are associated with a low number of T cells in extranodal locations
    Philipp Lohneis
    Institute of Pathology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Leuk Lymphoma 55:143-8. 2014
    ..In analogy to reactive monocytoid B lymphocytes, we also found a significantly lower relative amount of intratumoral T lymphocytes in extranodal MZL with monocytoid morphology...
  8. doi request reprint Differences in the T-bet and GATA-3 expression patterns between lymphocytic colitis and coeliac disease
    Korinna Johrens
    Institute for Pathology, Charite, Campus Benjamin Franklin, Medical University Berlin, Berlin, Germany
    Virchows Arch 457:451-6. 2010
    ..Also, most of the CD8+ lamina propria T cells in CD were T-bet+. We conclude that in contrast to CD, which exhibits immunophenotypical features of a Th1-response, LC shows features of a mixed Th1/Th2 immune response...
  9. ncbi request reprint Fibrosis in low-grade follicular lymphoma - a link to the TH2 immune reaction
    Philipp Lohneis
    a Institute of Pathology, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Leuk Lymphoma . 2016
    ....
  10. doi request reprint CT-guided radiofrequency ablation of osteoid osteoma using a novel battery-powered drill
    Dirk Schnapauff
    Department of Radiology, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Skeletal Radiol 44:695-701. 2015
    ..To evaluate the use of a novel battery-powered drill, enabling specimen requirement while drilling, in radiofrequency ablation of osteoid osteoma as an alternative to conventional orthopedic drills...
  11. pmc Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma
    Stephan Kreher
    Max Delbruck Center for Molecular Medicine, 13125 Berlin, Germany Hematology, Oncology, and Tumor Immunology, Charite Universitatsmedizin Berlin, 13353 Berlin, Germany
    Proc Natl Acad Sci U S A 111:E4513-22. 2014
    ..Our strategy efficiently identified a lymphoma type-specific key regulator and uncovered a tumor promoting role of IRF5. ..
  12. doi request reprint Bone Marrow work-up: report of a pilot study
    Ioannis Anagnostopoulos
    Institute for Pathology, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
    Recent Results Cancer Res 199:95-105. 2015
    ..These encouraging results imply that this novel decalcification solution will allow a widely accepted standardization of bone marrow trephine biopsy processing...
  13. doi request reprint Identification of a chemokine receptor profile characteristic for mediastinal large B-cell lymphoma
    Armin Rehm
    Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Int J Cancer 125:2367-74. 2009
    ..Furthermore, we suggest that low-abundance expression of CCR7 and CXCR5 may hinder lymphoma cells from nodal dissemination...
  14. pmc Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma
    Stephan Mathas
    Max Delbruck Center for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin, Germany
    Proc Natl Acad Sci U S A 106:5831-6. 2009
    ..Also, our data demonstrate that deregulation of breakpoint-proximal genes has a key role in ALCL...
  15. ncbi request reprint Age and cellular composition influence overall survival in a collective of non-immunocompromised patients with EBV-positive diffuse large B-cell lymphoma from a German lymphoma center
    Korinna Johrens
    a Institute of Pathology, Charité Medical University Berlin, Berlin, Germany
    Leuk Lymphoma 57:2791-2803. 2016
    ..Patients aged <50 years performed better than older ones while in patients aged ≥50 years only the cellular composition had an impact on overall survival...
  16. pmc Prognostic impact of programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor-infiltrating lymphocytes in ovarian high grade serous carcinoma
    Silvia Darb-Esfahani
    Institute of Pathology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Oncotarget 7:1486-99. 2016
    ..We systematically investigated PD-1 and PD-L1 expression patterns in the poor-prognosis tumor entity high-grade serous ovarian carcinoma...
  17. doi request reprint Human papilloma virus status of penile squamous cell carcinoma is associated with differences in tumour-infiltrating T lymphocytes
    Philipp Lohneis
    Institute of Pathology, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117, Berlin, Germany
    Virchows Arch 466:323-31. 2015
    ..The present study provides further evidence that the tumour microenvironment of HPV-positive carcinomas differs from that of HPV-negative carcinomas. ..
  18. doi request reprint Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha
    Björn Lamprecht
    Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Blood 112:3339-47. 2008
    ..Together, these data support the concept that aberrant expression of B lineage-inappropriate genes plays an important role for the biology of HL tumor cells...
  19. doi request reprint Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma
    Björn Lamprecht
    Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Nat Med 16:571-9, 1p following 579. 2010
    ..We conclude that LTR derepression is involved in the pathogenesis of human lymphomas, a finding that might have diagnostic, prognostic and therapeutic implications...
  20. pmc Increase of T and B cells and altered BACH2 expression patterns in bone marrow trephines of imatinib-treated patients with chronic myelogenous leukaemia
    Maximilian von Laffert
    Institute of Pathology, Charite Universitatsmedizin, D 10117 Berlin, Germany
    Oncol Lett 12:2421-2428. 2016
    ..As the present data are preliminary, future prospective studies are required to assess the prognostic and predictive role of BACH2 in patients with CML under targeted therapy...
  21. ncbi request reprint Non-mediastinal grey zone lymphomas and report from the workshop
    Harald Stein
    Institute of Pathology, Campus Benjamin Franklin, Charite Universitatsmedizin Berlin
    Eur J Haematol Suppl . 2005
    ....
  22. doi request reprint Increased T-helper 2 cytokines in bile from patients with IgG4-related cholangitis disrupt the tight junction-associated biliary epithelial cell barrier
    Tobias Müller
    Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Gastroenterology 144:1116-28. 2013
    ..A T-helper (Th) 2 cell cytokine profile predominates in liver tissues from these patients. We investigated whether Th2 cytokines disrupt the barrier function of biliary epithelial cells (BECs) in patients with IgG4-related cholangitis...
  23. ncbi request reprint T-bet-positive and IRTA1-positive monocytoid B cells differ from marginal zone B cells and epithelial-associated B cells in their antigen profile and topographical distribution
    Korinna Johrens
    Institute for Pathology, Charite, Campus Benjamin Franklin, Medical University Berlin, Germany
    Haematologica 90:1070-7. 2005
    ..To clarify this issue we studied the antigen profile and topographical distribution of these cell types...
  24. doi request reprint Harmonized PD-L1 immunohistochemistry for pulmonary squamous-cell and adenocarcinomas
    Andreas H Scheel
    University Hospital Cologne, Institute of Pathology, Cologne, Germany
    Mod Pathol 29:1165-72. 2016
    ..The four tested PD-L1 assays did not show comparable staining patterns in all cases. Thus, studies that correlate staining patterns and response to immunotherapy are required to test the significance of the observed differences. ..
  25. doi request reprint Prognostic impact of B-cell lymphoma 6 in primary CNS lymphoma
    Stephan Kreher
    Department of Hematology and Oncology, Campus Benjamin Franklin, Charite Berlin, Berlin, Germany S K, F S, E T, A K Institute of Pathology, Charite Berlin, Berlin, Germany K J Institute of Clinical Epidemiology and Applied Biostatistics, University Tuebingen, Tuebingen P M Institute of Neuropathology, University Bonn Medical Center, Brain Tumor Reference Center of the DGNN, Bonn, Germany K B, T P Institute of Neuropathology, Charite Berlin, Berlin, Germany J R, F H Department of Neurology, University Hospital Zurich, Zurich, Switzerland P R, M W
    Neuro Oncol 17:1016-21. 2015
    ....
  26. pmc A case series in patients with enteropathy and granulomatous diseases
    Tassilo Kruis
    Medical Department I Gastroenterology, Infectious Diseases, Rheumatology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, 12200, Germany
    BMC Gastroenterol 15:62. 2015
    ....
  27. doi request reprint Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT
    Angela Mensen
    Institute for Medical Immunology, Charite University Medicine, Berlin, Germany Experimental and Clinical Research Center, Berlin, Germany
    Blood 124:963-72. 2014
    ..This is associated with delayed B-cell reconstitution and impaired antibody response. Herein, KREC appears suitable to monitor BM B-cell output after transplant...
  28. doi request reprint CT guided bone biopsy using a battery powered intraosseous device
    Dirk Schnapauff
    Department of Radiology, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany
    Cardiovasc Intervent Radiol 36:1405-10. 2013
    ..To evaluate the feasibility of a battery powered intraosseous device to perform CT-fluoroscopy guided bone biopsy...
  29. doi request reprint Anti-cancer immune response mechanisms in neoadjuvant and targeted therapy
    Carsten Denkert
    Institute of Pathology, Charite Universitatsmedizin Berlin, 10117 Berlin, Germany
    Semin Immunopathol 33:341-51. 2011
    ..This review gives an overview on clinical data on response to classical chemotherapy as well as molecular targeted therapy and its interaction with the immune system...