Maja A Hofmann

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint Prospective evaluation of supportive care with or without CVD chemotherapy as a second-line treatment in advanced melanoma by patient's choice: a multicentre Dermatologic Cooperative Oncology Group trial
    Maja A Hofmann
    Department of Dermatology, Charite Universitatsmedizin, Berlin, Germany
    Melanoma Res 21:516-23. 2011
  2. pmc The monoclonal antibody SM5-1 recognizes a fibronectin variant which is widely expressed in melanoma
    Uwe Trefzer
    Department of Dermatology and Allergy, Skin Cancer Center, Charite Universitatsmedizin Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    BMC Cancer 6:8. 2006
  3. ncbi request reprint High-dose platinum combination therapy in pretreated patients with disseminated melanoma
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer Center, Charite Universitatsmedizin, Berlin, Germany
    Chemotherapy 53:422-8. 2007
  4. ncbi request reprint Prognostic factors and impact of treatment in melanoma brain metastases: better prognosis for women?
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer Centre, Charite Universitatsmedizin Berlin, Berlin, Germany
    Dermatology 215:10-6. 2007
  5. ncbi request reprint Complex combination biochemotherapy regimen in advanced metastatic melanoma in a non-intensive care unit: toxicity or benefit?
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer Centre, Charite Universitatsmedizin Berlin, Berlin, Germany
    Jpn J Clin Oncol 37:224-9. 2007
  6. doi request reprint Diagnostic value of melanoma inhibitory activity serum marker in the follow-up of patients with stage I or II cutaneous melanoma
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer Centre, Charite Universitatsmedizin Berlin, Berlin 10117, Germany
    Melanoma Res 19:17-23. 2009
  7. doi request reprint Serum TNF-α, B2M and sIL-2R levels are biological correlates of outcome in adjuvant IFN-α2b treatment of patients with melanoma
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer and Melanoma Center, Charite, Universitatsmedizin Berlin, Berlin, Germany
    J Cancer Res Clin Oncol 137:455-62. 2011
  8. doi request reprint Impact of lymph node metastases on serum level of melanoma inhibitory activity in stage III melanoma patients
    Maja A Hofmann
    Department of Dermatology and Allergy, Melanoma Center Department of Biomedical Statistics, Charite Universitatsmedizin Berlin, Germany
    J Dermatol 38:880-6. 2011
  9. ncbi request reprint Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases
    Maja Hofmann
    Department of Dermatology and Allergy, Charite University Medicine Berlin, Schumannstrasse 20 21, 10117, Berlin, Germany
    J Neurooncol 76:59-64. 2006
  10. ncbi request reprint Diffuse normolipemic plane xanthoma in a 9-year-old boy
    Maja Hofmann
    Department of Dermatology and Allergy, Charite, University Medicine Berlin, Germany
    Pediatr Dermatol 22:127-9. 2005

Collaborators

Detail Information

Publications21

  1. doi request reprint Prospective evaluation of supportive care with or without CVD chemotherapy as a second-line treatment in advanced melanoma by patient's choice: a multicentre Dermatologic Cooperative Oncology Group trial
    Maja A Hofmann
    Department of Dermatology, Charite Universitatsmedizin, Berlin, Germany
    Melanoma Res 21:516-23. 2011
    ..Interestingly, having the choice of chemotherapy or BSC alone in a second-line situation, more than 70% of patients chose polychemotherapy...
  2. pmc The monoclonal antibody SM5-1 recognizes a fibronectin variant which is widely expressed in melanoma
    Uwe Trefzer
    Department of Dermatology and Allergy, Skin Cancer Center, Charite Universitatsmedizin Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    BMC Cancer 6:8. 2006
    ..However, as compared to anti-S100, the antibody SM5-1 is highly specific for melanocytic lesions since 40 different neoplasms were found to be negative for SM5-1 by immunohistochemistry. The antigen recognized by SM5-1 is unknown...
  3. ncbi request reprint High-dose platinum combination therapy in pretreated patients with disseminated melanoma
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer Center, Charite Universitatsmedizin, Berlin, Germany
    Chemotherapy 53:422-8. 2007
    ..There are no accepted second-line therapeutic options in patients with disseminated melanoma. We evaluated toxicity and efficacy of a combination therapy with cisplatin and carboplatin...
  4. ncbi request reprint Prognostic factors and impact of treatment in melanoma brain metastases: better prognosis for women?
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer Centre, Charite Universitatsmedizin Berlin, Berlin, Germany
    Dermatology 215:10-6. 2007
    ..Brain metastases are a common consequence in patients with stage IV melanoma associated with a grim prognosis...
  5. ncbi request reprint Complex combination biochemotherapy regimen in advanced metastatic melanoma in a non-intensive care unit: toxicity or benefit?
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer Centre, Charite Universitatsmedizin Berlin, Berlin, Germany
    Jpn J Clin Oncol 37:224-9. 2007
    ..Different biochemotherapy protocols showed promise with high response rates, but again without significant impact on survival...
  6. doi request reprint Diagnostic value of melanoma inhibitory activity serum marker in the follow-up of patients with stage I or II cutaneous melanoma
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer Centre, Charite Universitatsmedizin Berlin, Berlin 10117, Germany
    Melanoma Res 19:17-23. 2009
    ..Additional prospective studies to clarify the clinical combination with other serum markers seem promising...
  7. doi request reprint Serum TNF-α, B2M and sIL-2R levels are biological correlates of outcome in adjuvant IFN-α2b treatment of patients with melanoma
    Maja A Hofmann
    Department of Dermatology and Allergy, Skin Cancer and Melanoma Center, Charite, Universitatsmedizin Berlin, Berlin, Germany
    J Cancer Res Clin Oncol 137:455-62. 2011
    ..We examined serum cytokine levels in IFN-α-treated patients to find potential biological markers for response or toxicity...
  8. doi request reprint Impact of lymph node metastases on serum level of melanoma inhibitory activity in stage III melanoma patients
    Maja A Hofmann
    Department of Dermatology and Allergy, Melanoma Center Department of Biomedical Statistics, Charite Universitatsmedizin Berlin, Germany
    J Dermatol 38:880-6. 2011
    ..52 ng/mL). The MIA serum marker can be helpful in patients undergoing lymph node dissection. Furthermore, during follow up, patients showing relapsing diseases can have an elevated MIA value...
  9. ncbi request reprint Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases
    Maja Hofmann
    Department of Dermatology and Allergy, Charite University Medicine Berlin, Schumannstrasse 20 21, 10117, Berlin, Germany
    J Neurooncol 76:59-64. 2006
    ..Our results demonstrate that temozolomide can be combined with radiotherapy for the treatment of brain metastases in malignant melanoma, and that this combination may prolong survival in this patient group...
  10. ncbi request reprint Diffuse normolipemic plane xanthoma in a 9-year-old boy
    Maja Hofmann
    Department of Dermatology and Allergy, Charite, University Medicine Berlin, Germany
    Pediatr Dermatol 22:127-9. 2005
    ..It is important to perform regular follow-up of these patients because normolipemic plane xanthoma often precedes myeloproliferative disorders such as leukemia, paraproteinemia, or lymphoma...
  11. ncbi request reprint Diffuse melanosis cutis in disseminated malignant melanoma
    Maja Hofmann
    Department of Dermatology and Allergy, Charite University Medicine Berlin, CCM, Germany
    Dermatology 209:350-2. 2004
  12. ncbi request reprint Large primary meningeal melanoma in an adult patient with neurocutaneous melanosis
    Felix Kiecker
    Department of Dermatology and Allergy, Skin Cancer Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Clin Neurol Neurosurg 109:448-51. 2007
    ..This phenomenon should be kept in mind when observing patients with such skin lesions, even if they are of minor extent...
  13. doi request reprint Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma
    Maja A Hofmann
    Department of Dermatology, Venerology and Allergy, Skin Cancer Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Immunother 31:520-7. 2008
    ..Despite the relatively low dosage, clinical activity was demonstrated both in patients with BCC and with cutaneous or subcutaneous metastatic melanoma lesions...
  14. pmc Long-term therapy of interferon-alpha induced pulmonary arterial hypertension with different PDE-5 inhibitors: a case report
    Nicoline Jochmann
    Department of Cardiology, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Cardiovasc Ultrasound 3:26. 2005
    ..Interferon alpha2 is widely used in hepatitis and high-risk melanoma. Interferon-induced pulmonary arterial hypertension as a side effect is rare...
  15. ncbi request reprint The tumor suppressive reagent taurolidine inhibits growth of malignant melanoma--a mouse model
    Chris Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Charite Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany
    J Surg Res 143:372-8. 2007
    ..TRD has been shown to induce apoptosis of melanoma cells in vitro. Therefore, the effects of TRD on disseminated melanoma were evaluated in a mice model...
  16. ncbi request reprint Cytokine and anticytokine therapy in dermatology
    Uwe Trefzer
    Department of Dermatology and Allergy, University Hospital Charite, Berlin Humboldt University, Berlin, Germany
    Expert Opin Biol Ther 3:733-43. 2003
    ..In this review, the current status of cytokine and anticytokine therapy for skin diseases is discussed...
  17. ncbi request reprint Concordant loss of melanoma differentiation antigens in synchronous and asynchronous melanoma metastases: implications for immunotherapy
    Uwe Trefzer
    Department of Dermatology and Allergy, Skin Cancer Centre, Charite Universitatsmedizin Berlin, Berlin, Germany
    Melanoma Res 16:137-45. 2006
    ..In conclusion, broader polypeptide vaccines should be used for melanoma immunotherapy...
  18. doi request reprint A systematic review of the role of interleukin-17 and the interleukin-20 family in inflammatory allergic skin diseases
    Maja A Hofmann
    Department of Dermatology and Allergy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Curr Opin Allergy Clin Immunol 16:451-7. 2016
    ..But new cytokines and T cells have been discovered within the last years. In this systematic review, the focus is laid on interleukin-17 (IL-17) and the interleukin-20 (IL-20) family which appear to be fine-tuning the Th2-driven answer...
  19. ncbi request reprint Impact of sentinel lymph node biopsy in patients with Merkel cell carcinoma: results of a prospective study and review of the literature
    Sofiane Maza
    Clinic for Nuclear Medicine, Charite, Universitatsmedizin Berlin, Schumannstrasse 20 21, 10117, Berlin, Germany
    Eur J Nucl Med Mol Imaging 33:433-40. 2006
    ..The aim of this prospective study was to examine the feasibility and clinical impact of sentinel lymph node biopsy (SLNB) in this cutaneous malignancy...
  20. ncbi request reprint Expression of the human endogenous retrovirus-K transmembrane envelope, Rec and Np9 proteins in melanomas and melanoma cell lines
    Kristina Büscher
    Robert Koch Institute, Berlin, Germany
    Melanoma Res 16:223-34. 2006
    ..Additional experiments are needed to determine their involvement, if any, in cell proliferation and tumor progression...
  21. ncbi request reprint Expression of human endogenous retrovirus K in melanomas and melanoma cell lines
    Kristina Büscher
    Robert Koch Institute and Department of Dermatology, Campus Charite Mitte, Charite University Medicine Berlin, Berlin, Germany
    Cancer Res 65:4172-80. 2005
    ..For the first time, antibodies against HERV-K were found in melanoma patients. Melanomas are, in addition to teratocarcinomas and human breast cancer, the third tumor type with enhanced expression of HERV-K...