Andreas Heinz

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. pmc Identifying the neural circuitry of alcohol craving and relapse vulnerability
    Andreas Heinz
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charité Mitte, Germany
    Addict Biol 14:108-18. 2009
  2. doi request reprint Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics
    Anne Beck
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Biol Psychiatry 66:734-42. 2009
  3. doi request reprint Effect of brain structure, brain function, and brain connectivity on relapse in alcohol-dependent patients
    Anne Beck
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin, Campus Mitte, Berlin, Germany
    Arch Gen Psychiatry 69:842-52. 2012
  4. doi request reprint Childhood methylphenidate treatment of ADHD and response to affective stimuli
    Lorna Schlochtermeier
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur Neuropsychopharmacol 21:646-54. 2011
  5. doi request reprint A preliminary study of increased amygdala activation to positive affective stimuli in mania
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Bipolar Disord 11:70-5. 2009
  6. doi request reprint Altered representation of expected value in the orbitofrontal cortex in mania
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Hum Brain Mapp 31:958-69. 2010
  7. pmc Prefrontal cortex fails to learn from reward prediction errors in alcohol dependence
    Soyoung Q Park
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Neurosci 30:7749-53. 2010
  8. doi request reprint Context insensitivity during positive and negative emotional expectancy in depression assessed with functional magnetic resonance imaging
    Melanie Feeser
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychiatry Res 212:28-35. 2013
  9. doi request reprint Prescription patterns of patients diagnosed with schizophrenia in mental hospitals in Tashkent/Uzbekistan and in four German cities
    Adrian P Mundt
    Department of Psychiatry and Psychotherapy, Charité Campus Mitte Universitätsmedizin Berlin, Germany
    Pharmacoepidemiol Drug Saf 21:145-51. 2012
  10. pmc Dopaminergic dysfunction in schizophrenia: salience attribution revisited
    Andreas Heinz
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Charite Campus Mitte, 10117 Berlin, Germany
    Schizophr Bull 36:472-85. 2010

Detail Information

Publications128 found, 100 shown here

  1. pmc Identifying the neural circuitry of alcohol craving and relapse vulnerability
    Andreas Heinz
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charité Mitte, Germany
    Addict Biol 14:108-18. 2009
    ..These findings are discussed with respect to psychotherapeutic and pharmacological treatment options...
  2. doi request reprint Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics
    Anne Beck
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Biol Psychiatry 66:734-42. 2009
    ..We explored whether functional brain activation during anticipation of incentive stimuli is associated with impulsiveness in detoxified alcoholics and healthy control subjects...
  3. doi request reprint Effect of brain structure, brain function, and brain connectivity on relapse in alcohol-dependent patients
    Anne Beck
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin, Campus Mitte, Berlin, Germany
    Arch Gen Psychiatry 69:842-52. 2012
    ..In alcohol-dependent patients, brain atrophy and functional brain activation elicited by alcohol-associated stimuli may predict relapse. However, to date, the interaction between both factors has not been studied...
  4. doi request reprint Childhood methylphenidate treatment of ADHD and response to affective stimuli
    Lorna Schlochtermeier
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur Neuropsychopharmacol 21:646-54. 2011
    ..Further prospective studies need to clarify direct and indirect mechanisms of MPH treatment that may contribute to emotional processing, which is dysfunctional in males without pharmacological treatment in childhood...
  5. doi request reprint A preliminary study of increased amygdala activation to positive affective stimuli in mania
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Bipolar Disord 11:70-5. 2009
    ..The present study in hypomanic and manic patients explored how amygdala responses to affective stimuli depend on the valence of the stimuli presented...
  6. doi request reprint Altered representation of expected value in the orbitofrontal cortex in mania
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Hum Brain Mapp 31:958-69. 2010
    ..Here we studied neural correlates of gain and loss expectation in mania using functional magnetic resonance imaging (fMRI)...
  7. pmc Prefrontal cortex fails to learn from reward prediction errors in alcohol dependence
    Soyoung Q Park
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Neurosci 30:7749-53. 2010
    ..Furthermore, they extend the scope of neurobiological deficits underlying addiction beyond the focus on the striatum...
  8. doi request reprint Context insensitivity during positive and negative emotional expectancy in depression assessed with functional magnetic resonance imaging
    Melanie Feeser
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychiatry Res 212:28-35. 2013
    ..This hyporeactivity may contribute to clinical features like anergia, apathy, and loss of motivation in the context of both positive and negative incentives...
  9. doi request reprint Prescription patterns of patients diagnosed with schizophrenia in mental hospitals in Tashkent/Uzbekistan and in four German cities
    Adrian P Mundt
    Department of Psychiatry and Psychotherapy, Charité Campus Mitte Universitätsmedizin Berlin, Germany
    Pharmacoepidemiol Drug Saf 21:145-51. 2012
    ....
  10. pmc Dopaminergic dysfunction in schizophrenia: salience attribution revisited
    Andreas Heinz
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Charite Campus Mitte, 10117 Berlin, Germany
    Schizophr Bull 36:472-85. 2010
    ....
  11. doi request reprint Acute exercise influences reward processing in highly trained and untrained men
    Nina Bothe
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    Med Sci Sports Exerc 45:583-91. 2013
    ..To address this issue, we examined highly trained (HT) physically inactive (PIA) men with a monetary incentive delay (MID) paradigm...
  12. doi request reprint Hyporeactivity of ventral striatum towards incentive stimuli in unmedicated depressed patients normalizes after treatment with escitalopram
    Meline Stoy
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Psychopharmacol 26:677-88. 2012
    ..These findings suggest that MDD patients show ventral striatal hyporesponsiveness during incentive cue processing, which normalizes after successful treatment...
  13. doi request reprint Subtle deficits of cognitive theory of mind in unaffected first-degree relatives of schizophrenia patients
    Christiane Montag
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Mitte, Germany
    Eur Arch Psychiatry Clin Neurosci 262:217-26. 2012
    ..Findings corroborate the assumption of distinct social-cognitive abilities as an intermediate phenotype for schizophrenia...
  14. doi request reprint Delineating self-referential processing from episodic memory retrieval: common and dissociable networks
    Bastian Sajonz
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Neuroimage 50:1606-17. 2010
    ....
  15. doi request reprint Altered amygdala activation in schizophrenia patients during emotion processing
    Anne Pankow
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Germany Electronic address
    Schizophr Res 150:101-6. 2013
    ..These results might represent a correlate of altered emotional experience in schizophrenia patients who are known to report less positive and more negative affective states in daily life situations...
  16. doi request reprint Cue reactivity and its inhibition in pathological computer game players
    Robert C Lorenz
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Germany
    Addict Biol 18:134-46. 2013
    ..Together with the connectivity result, these findings suggest that top-down inhibitory processes might suppress the cue reactivity-related neural activity in long-presentation trials...
  17. pmc Regional patterns and clinical correlates of basal ganglia morphology in non-medicated schizophrenia
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Berlin, Germany
    Schizophr Res 106:140-7. 2008
    ....
  18. pmc Ventral striatal prediction error signaling is associated with dopamine synthesis capacity and fluid intelligence
    Florian Schlagenhauf
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Germany
    Hum Brain Mapp 34:1490-9. 2013
    ....
  19. doi request reprint Functional neuroanatomy of emotion processing in major depressive disorder is altered after successful antidepressant therapy
    Gabriela Rosenblau
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Psychopharmacol 26:1424-33. 2012
    ..These findings show that the neural mechanisms of emotion anticipation and processing are altered in patients with MDD and that these alterations are able to normalize after treatment with an antidepressant...
  20. doi request reprint Reward processing in male adults with childhood ADHD--a comparison between drug-naïve and methylphenidate-treated subjects
    Meline Stoy
    Department of Psychiatry and Psychotherapy Campus Charité Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Psychopharmacology (Berl) 215:467-81. 2011
    ..Dysfunctional reward processing has been proposed as a main deficit in attention-deficit/hyperactivity disorder (ADHD), which could be modulated by treatment with methylphenidate (MPH)...
  21. doi request reprint Lesion of the medial prefrontal cortex and the subthalamic nucleus selectively affect depression-like behavior in rats
    Julia Klein
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, University Medicine Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Behav Brain Res 213:73-81. 2010
    ....
  22. doi request reprint Test-performance after cognitive training in persons at risk mental state of schizophrenia and patients with schizophrenia
    Stephan Rauchensteiner
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Germany
    Psychiatry Res 185:334-9. 2011
    ..These results should be confirmed by further investigations including larger sample sizes...
  23. doi request reprint Sense of agency is altered in patients with a putative psychotic prodrome
    Marta Hauser
    Department of Psychiatry and Psychotherapy, Charité University Medicine Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Schizophr Res 126:20-7. 2011
    ..e. in patients with a putative psychotic prodrome (PP). Previous research has shown that time judgments of voluntary actions can provide an implicit measure of the SoAg...
  24. doi request reprint Reward feedback alterations in unmedicated schizophrenia patients: relevance for delusions
    Florian Schlagenhauf
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Germany
    Biol Psychiatry 65:1032-9. 2009
    ..Increased attribution of incentive salience to neutral or aversive stimuli might be associated with dysfunction of neuronal processing of positive and negative reinforcement and contribute to the formation of delusions in schizophrenia...
  25. doi request reprint Delusions and the role of beliefs in perceptual inference
    Katharina Schmack
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Neurosci 33:13701-12. 2013
    ..In contrast, stronger higher-level predictions that sculpt perception into conformity with beliefs might contribute to the tenacious persistence of delusional beliefs. ..
  26. doi request reprint Apparent motion perception in patients with paranoid schizophrenia
    Lia Lira Olivier Sanders
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 263:233-9. 2013
    ..These results suggest that schizophrenia may be associated with a reduced susceptibility to visual phenomena that commonly rely on perceptual inference...
  27. doi request reprint Dorsal striatal-midbrain connectivity in humans predicts how reinforcements are used to guide decisions
    Thorsten Kahnt
    Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin Charité Campus Mitte, Berlin, Germany
    J Cogn Neurosci 21:1332-45. 2009
    ..These results suggest that connections between the putative SN and the DS are critical for modulating action values in the DS according to both positive and negative reinforcements to guide future decision making...
  28. doi request reprint Different aspects of theory of mind in paranoid schizophrenia: evidence from a video-based assessment
    Christiane Montag
    Charite University Medicine Berlin, Department of Psychiatry and Psychotherapy, Campus Mitte, Berlin, Germany
    Psychiatry Res 186:203-9. 2011
    ..In schizophrenic patients, negative symptoms were associated with a lack of a mental state concept, while positive symptoms like delusions were associated with 'overmentalizing', supporting respective etiological concepts of delusions...
  29. doi request reprint Dopamine in amygdala gates limbic processing of aversive stimuli in humans
    Thorsten Kienast
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite University Medicine Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Nat Neurosci 11:1381-2. 2008
    ..Our results suggest that individual dopamine storage capacity in amygdala subserves modulation of emotional processing in amygdala and dorsal cingulate, thereby contributing to individual differences in anxious temperament...
  30. doi request reprint Serotonergic dysfunction in the prodromal, first-episode and chronic course of schizophrenia as assessed by the loudness dependence of auditory evoked activity
    Yehonala Gudlowski
    Department of Psychiatry and Psychotherapy, Charite, University Medicine of Berlin, Campus Mitte, Berlin, Germany
    Schizophr Res 109:141-7. 2009
    ..A weak LDAEP may therefore represent a vulnerability marker rather than an expression of illness progression...
  31. doi request reprint Activity modulation of the globus pallidus and the nucleus entopeduncularis affects compulsive checking in rats
    Anaïs Djodari-Irani
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Behav Brain Res 219:149-58. 2011
    ....
  32. pmc Theory of mind network activity is altered in subjects with familial liability for schizophrenia
    Sebastian Mohnke
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Soc Cogn Affect Neurosci 11:299-307. 2016
    ..Enhanced recruitment of posterior ToM areas in relatives might indicate inefficiency mechanisms in the presence of genetic risk. ..
  33. doi request reprint Frontal glutamate and reward processing in adolescence and adulthood
    Tobias Gleich
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Brain Struct Funct 220:3087-99. 2015
    ..This fronto-limbic coupling may represent a vulnerability factor for psychiatric disorders starting in adolescence but not in adulthood. ..
  34. pmc Dimensional psychiatry: reward dysfunction and depressive mood across psychiatric disorders
    Claudia Hägele
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
    Psychopharmacology (Berl) 232:331-41. 2015
    ..A dimensional approach in psychiatry aims to identify core mechanisms of mental disorders across nosological boundaries...
  35. pmc Chronic alcohol intake abolishes the relationship between dopamine synthesis capacity and learning signals in the ventral striatum
    Lorenz Deserno
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117, Berlin, Germany Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany Department of Neurology, Otto von Guericke University, Magdeburg, Germany
    Eur J Neurosci 41:477-86. 2015
    ..Alcohol intake may perpetuate itself by interfering with dopaminergic modulation of neural learning signals in the ventral striatum, thus increasing craving for habitual drug intake...
  36. doi request reprint Efficacy and safety of levetiracetam for the prevention of alcohol relapse in recently detoxified alcohol-dependent patients: a randomized trial
    Christoph Richter
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    J Clin Psychopharmacol 32:558-62. 2012
    ..Antiepileptics have been shown to reduce alcohol intake or to prevent relapse in patients with alcoholism...
  37. doi request reprint Decline in prefrontal catecholamine synthesis explains age-related changes in cognitive speed beyond regional grey matter atrophy
    Jan Kalbitzer
    Department of Psychiatry and Psychotherapy, Campus Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Eur J Nucl Med Mol Imaging 39:1462-6. 2012
    ..Age-related decline in cognitive speed has been associated with prefrontal dopamine D1 receptor availability, but the contribution of presynaptic dopamine and noradrenaline innervation to age-related changes in cognition is unknown...
  38. doi request reprint Efficacy and safety of pregabalin in the treatment of alcohol withdrawal syndrome: a randomized placebo-controlled trial
    Anna Förg
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, D 10117 Berlin, Germany
    Alcohol Alcohol 47:149-55. 2012
    ..The objective of this study was to collect preliminary data on the efficacy and safety of pregabalin in attenuating the severity of alcohol withdrawal symptoms during detoxification treatment in alcohol dependence...
  39. doi request reprint Neurobiological correlates of delusion: beyond the salience attribution hypothesis
    Anne Pankow
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Neuropsychobiology 66:33-43. 2012
    ..Neuroleptic medication, on the other hand, appears to interfere with anticipation of reward in the ventral striatum and can thus contribute to secondary negative symptoms such as apathy and avolition...
  40. ncbi request reprint Reward system activation in schizophrenic patients switched from typical neuroleptics to olanzapine
    Florian Schlagenhauf
    Department of Psychiatry and Psychotherapy, Charite University Medical Center, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychopharmacology (Berl) 196:673-84. 2008
    ..This may not be the case with newer neuroleptics such as olanzapine, which show less dopamine D2 receptor blockade and a faster off-rate from the receptor...
  41. doi request reprint Pavlovian-to-instrumental transfer effects in the nucleus accumbens relate to relapse in alcohol dependence
    Maria Garbusow
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Germany
    Addict Biol 21:719-31. 2016
    ..These observations show for the first time that PIT-related BOLD signals, as a measure of the influence of Pavlovian cues on instrumental behavior, predict alcohol intake and relapse in alcohol dependence. ..
  42. doi request reprint Maternal parenting behavior and emotion processing in adolescents-An fMRI study
    Lydia Romund
    Charite Universitatsmedizin Berlin, Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany Electronic address
    Biol Psychol 120:120-125. 2016
    ..These results expand existent findings in maltreated children to healthy populations...
  43. doi request reprint Reversal learning strategy in adolescence is associated with prefrontal cortex activation
    Rebecca Boehme
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, 10117, Germany
    Eur J Neurosci . 2016
    ..These findings support the hypothesis that the prefrontal cortex is implicated in mediating flexible goal-directed behavioral control...
  44. doi request reprint Effects of cognitive bias modification training on neural signatures of alcohol approach tendencies in male alcohol-dependent patients
    Corinde E Wiers
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Germany
    Addict Biol 20:990-9. 2015
    ..This suggests that CBM affects neural mechanisms involved in the automatic alcohol approach bias, which may be important for the clinical effectiveness of CBM. ..
  45. doi request reprint Detection of visual events along the apparent motion trace in patients with paranoid schizophrenia
    Lia Lira Olivier Sanders
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Psychiatry Res 198:216-23. 2012
    ....
  46. doi request reprint Reduced prefrontal-parietal effective connectivity and working memory deficits in schizophrenia
    Lorenz Deserno
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, 10117 Berlin, Germany
    J Neurosci 32:12-20. 2012
    ..Moreover, this study in a large sample of patients reveals a mechanism underlying prefrontal inefficiency and cognitive deficits in schizophrenia, thereby providing direct experimental evidence for the dysconnectivity hypothesis...
  47. doi request reprint Altered awareness of action in schizophrenia: a specific deficit in predicting action consequences
    Martin Voss
    Department of Psychiatry and Psychotherapy, Charite University Hospital, St Hedwig Hospital, Grosse Hamburger Strasse 5 11, Berlin, Germany
    Brain 133:3104-12. 2010
    ..The failure to predict the effects of one's own actions may underlie the blurring and confusion in the relationship between the self and the world that characterizes acute psychosis...
  48. doi request reprint Neural correlates of the self-concept in adolescence-A focus on the significance of friends
    Lydia Romund
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    Hum Brain Mapp . 2016
    ..Results support behavioral findings of a greater relevance of friends for the development of a self-concept during adolescence and indicate underlying functional brain processes. Hum Brain Mapp, 2016. © 2016 Wiley Periodicals, Inc...
  49. doi request reprint Subjective illusion of control modulates striatal reward anticipation in adolescence
    Robert C Lorenz
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany Institute of Psychology, Humboldt Universitat zu Berlin, Rudower Chaussee 18, 12489 Berlin, Germany Center for Adaptive Rationality, Max Planck Institute for Human Development, Lentzeallee 94, 14195 Berlin, Germany Electronic address
    Neuroimage 117:250-7. 2015
    ..This finding strengthens the notion that subjectively perceived control, not necessarily the objective presence of control, affects striatal reward-related processing. ..
  50. pmc Aberrant Salience Is Related to Dysfunctional Self-Referential Processing in Psychosis
    Anne Pankow
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Schizophr Bull 42:67-76. 2016
    ..We investigated the neural correlates of self-referential processing, aberrant salience attribution, and the relationship between these 2 measures across the psychosis continuum...
  51. doi request reprint Segregation of face sensitive areas within the fusiform gyrus using global signal regression? A study on amygdala resting-state functional connectivity
    Johann D Kruschwitz
    Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Hum Brain Mapp 36:4089-103. 2015
    ..In this article, we discuss the potential of GSR to segregate face sensitive areas within the FFG and furthermore discuss how our results may relate to the functional organization of the face-perception circuit...
  52. pmc Ventral striatal dopamine reflects behavioral and neural signatures of model-based control during sequential decision making
    Lorenz Deserno
    Max Planck Fellow Group Cognitive and Affective Control of Behavioral Adaptation, Max Planck Institute for Human Cognitive and Brain Sciences, 04130 Leipzig, Germany Department of Neurology, Otto von Guericke University, 39118 Magdeburg, Germany Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, 10115 Berlin, Germany
    Proc Natl Acad Sci U S A 112:1595-600. 2015
    ..Our data provide a novel perspective on how alterations in presynaptic dopamine levels might be accompanied by a disruption of behavioral control as observed in aging or neuropsychiatric diseases such as schizophrenia and addiction. ..
  53. doi request reprint Model-based and model-free decisions in alcohol dependence
    Miriam Sebold
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Neuropsychobiology 70:122-31. 2014
    ..Human and animal work suggests a shift from goal-directed to habitual decision-making in addiction. However, the evidence for this in human alcohol dependence is as yet inconclusive...
  54. pmc The effects of life stress and neural learning signals on fluid intelligence
    Eva Friedel
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, 10117, Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 265:35-43. 2015
    ..The results suggest that an understanding of the neurobiological correlates of trait variables like fluid IQ needs to take socioemotional influences such as chronic stress into account. ..
  55. doi request reprint Mapping brain regions in which deep brain stimulation affects schizophrenia-like behavior in two rat models of schizophrenia
    Julia Klein
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Germany
    Brain Stimul 6:490-9. 2013
    ....
  56. doi request reprint Working memory load-dependent brain response predicts behavioral training gains in older adults
    Stephan Heinzel
    Department of Psychology, Humboldt Universitat zu Berlin, D 12489 Berlin, Germany, Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, D 10117 Berlin, Germany, Social and Preventive Medicine, University of Potsdam, D 14469 Potsdam, Germany, and Cluster of Excellence NeuroCure, Charite Universitatsmedizin Berlin, D 10117 Berlin, Germany
    J Neurosci 34:1224-33. 2014
    ..e., increasing activation with increasing WM load) of a WM-related network predict plasticity of the WM system, whereas WM training may specifically increase neural efficiency in older adults. ..
  57. doi request reprint Dietrich Bonhoeffer (1906-1945)
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Am J Psychiatry 165:577-8. 2008
  58. doi request reprint Common structural correlates of trait impulsiveness and perceptual reasoning in adolescence
    Christina Schilling
    Department of Psychiatry and Psychotherapy, Charité University Medicine Campus Mitte, Berlin, Germany
    Hum Brain Mapp 34:374-83. 2013
    ..This study investigates whether there are common structural cerebral correlates of trait impulsiveness and cognitive functioning in a large sample of healthy adolescents from the IMAGEN project...
  59. pmc Rationale and baseline characteristics of PREVENT: a second-generation intervention trial in subjects at-risk (prodromal) of developing first-episode psychosis evaluating cognitive behavior therapy, aripiprazole, and placebo for the prevention of psychosi
    Andreas Bechdolf
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50924 Cologne, Germany
    Schizophr Bull 37:S111-21. 2011
    ..When the final results of the trial are available, PREVENT will substantially expand the current limited evidence base for best clinical practice in people at-risk (prodromal) of first-episode psychosis...
  60. pmc Hemispheric asymmetry for affective stimulus processing in healthy subjects--a fMRI study
    Esther Beraha
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    PLoS ONE 7:e46931. 2012
    ..However, experimental evidence for these hypotheses remains inconclusive, partly because direct comparisons between hemispheres are scarce...
  61. doi request reprint Prediction of psychosis in adolescents and young adults at high risk: results from the prospective European prediction of psychosis study
    Stephan Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    Arch Gen Psychiatry 67:241-51. 2010
    ..Existing criteria need improvement in terms of specificity and individual risk assessment to allow for better targeted and earlier interventions...
  62. doi request reprint Hippocampal and frontolimbic function as intermediate phenotype for psychosis: evidence from healthy relatives and a common risk variant in CACNA1C
    Susanne Erk
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Campus Mitte Division of Mind and Brain Research, Charite Universitatsmedizin Berlin, Campus Mitte Electronic address
    Biol Psychiatry 76:466-75. 2014
    ..To test whether this brain systems-level abnormality is a potential intermediate phenotype for psychiatric disorder, we studied unaffected relatives of patients with bipolar disorder, major depression, and schizophrenia...
  63. doi request reprint Aberrant Salience Is Related to Reduced Reinforcement Learning Signals and Elevated Dopamine Synthesis Capacity in Healthy Adults
    Rebecca Boehme
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin, 10117 Berlin, Germany
    J Neurosci 35:10103-11. 2015
    ..These data provide the first evidence for a specific link between the constructs of aberrant salience attribution, reduced RPE processing, and potentially increased presynaptic dopamine function. ..
  64. pmc Striatal dysfunction during reversal learning in unmedicated schizophrenia patients
    Florian Schlagenhauf
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Germany Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany Electronic address
    Neuroimage 89:171-80. 2014
    ..This result highlights VS dysfunction is tightly linked to a reward-related reversal learning deficit in early, unmedicated schizophrenia patients. ..
  65. doi request reprint Theodor Lipps and the concept of empathy: 1851-1914
    Christiane Montag
    Department of Psychiatry and Psychotherapy, Psychiatric University Hospital at St Hedwig Krankenhaus, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Am J Psychiatry 165:1261. 2008
  66. doi request reprint Use of psychiatric inpatient capacities and diagnostic practice in Tashkent/Uzbekistan as compared to Berlin/Germany
    Adrian P Mundt
    Psychiatrische Universitätsklinik der Charité im St Hedwig Krankenhaus, Charite Universitatsmedizin Berlin, Müllerstr 56 58, 13349 Berlin, Germany
    Soc Psychiatry Psychiatr Epidemiol 46:1295-302. 2011
    ..Differential diagnostic practices related to different traditions in psychopathology between the two settings are analysed to explain part of the difference in relative frequencies of the diagnoses...
  67. doi request reprint Attentional modulation of emotional stimulus processing in patients with major depression--alterations in prefrontal cortical regions
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Neurosci Lett 463:108-13. 2009
    ..Altered prefrontal modulation in depression may contribute to impaired affect modulation and related clinical symptoms, such as anhedonia...
  68. pmc Mapping callosal morphology in early- and late-onset elderly depression: an index of distinct changes in cortical connectivity
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin, Germany
    Neuropsychopharmacology 33:1528-36. 2008
    ..Patients with a late onset of depression may be at higher risk of illness progression and eventually dementia conversion than early-onset depression, with potentially important implications for research and therapy...
  69. pmc Diagnostic classification of schizophrenia patients on the basis of regional reward-related FMRI signal patterns
    Stefan P Koch
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Germany
    PLoS ONE 10:e0119089. 2015
    ..These results show that MVPA can be used to substantially increase the accuracy of diagnostic classification on the basis of task-related fMRI signal patterns in a regionally specific way. ..
  70. pmc Alcohol-related aggression-social and neurobiological factors
    Anne Beck
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin
    Dtsch Arztebl Int 110:711-5. 2013
    ..In 2011, nearly one in three violent acts in Germany was committed under the influence of alcohol (31.8%). The link between alcohol consumption and aggression is promoted by various interacting factors...
  71. doi request reprint Increased neural activity during high working memory load predicts low relapse risk in alcohol dependence
    Katrin Charlet
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Germany
    Addict Biol 19:402-14. 2014
    ....
  72. doi request reprint Altered reward processing in adolescents with prenatal exposure to maternal cigarette smoking
    Kathrin U Müller
    Section of Neuroscience Systems, Department of Psychiatry and Psychotherapy, and Neuroimaging Center, Technische Universitat Dresden, Dresden, Germany
    JAMA Psychiatry 70:847-56. 2013
    ..However, no study has examined the effect of maternal smoking on the offspring's brain response during reward processing...
  73. doi request reprint Exercise and physical activity in mental disorders
    Elisabeth Wolff
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 261:S186-91. 2011
    ..Mechanisms of the therapeutic effects of EX/PA are summarized, including metabolic and physiological as well as psychological aspects. Finally, implications for research and therapeutic practice are illustrated...
  74. pmc Prefrontal cortex glutamate correlates with mental perspective-taking
    Christiane Montag
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    PLoS ONE 3:e3890. 2008
    ..However, the role of the glutamate system for different dimensions of empathy has not been investigated so far...
  75. doi request reprint High-frequency stimulation of the nucleus accumbens core and shell reduces quinpirole-induced compulsive checking in rats
    Adrian Mundt
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Charite University Medicine, Berlin, Germany
    Eur J Neurosci 29:2401-12. 2009
    ..We therefore conclude that both, the NAc core and shell constitute potential target structures in the treatment of OCD...
  76. ncbi request reprint Levetiracetam for the treatment of alcohol withdrawal syndrome: a multicenter, prospective, randomized, placebo-controlled trial
    Christoph Richter
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Germany
    J Clin Psychopharmacol 30:720-5. 2010
    ..We therefore investigated the safety and efficacy of levetiracetam (LV), a newer antiepileptic with a potentially favorable adverse-effect profile, for the treatment of AWS...
  77. doi request reprint Algorithm-guided treatment of depression reduces treatment costs--results from the randomized controlled German Algorithm Project (GAPII)
    Roland Ricken
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Germany
    J Affect Disord 134:249-56. 2011
    ..The objective of this study was a health economic evaluation of SSTR based on a cost effectiveness analysis (CEA)...
  78. doi request reprint Pharmacoepidemiology of patients hospitalized for somatoform disorders in psychiatric hospitals and departments
    Adrian Mundt
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Universitatsmedizin Berlin, Germany
    Pharmacoepidemiol Drug Saf 19:687-93. 2010
    ..We evaluated the current pharmacological treatment strategies used for psychiatric in-patients diagnosed with SD in Central Europe...
  79. ncbi request reprint Reward anticipation and outcomes in adult males with attention-deficit/hyperactivity disorder
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Neuroimage 39:966-72. 2008
    ..These findings suggest that male adults with ADHD show neural signs of abnormal reward processing. Future studies will have to investigate whether these dysfunctional patterns might be normalized by treatment...
  80. doi request reprint Theory of mind impairments in euthymic bipolar patients
    Christiane Montag
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    J Affect Disord 123:264-9. 2010
    ..In bipolar affective disorder, evidence for ToM deficits is scant, although brain imaging studies and impairments in non-social neurocognitive domains indicate deficits of prefrontal functions...
  81. ncbi request reprint Effects of acute psychological stress on adhesion molecules, interleukins and sex hormones: implications for coronary heart disease
    Andreas Heinz
    Department of Psychiatry of the Charité, Humboldt University of Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Psychopharmacology (Berl) 165:111-7. 2003
    ..Cell adhesion molecules may be activated by psychological stress exposure, depending on their interaction with the interleukin network, sex hormones and cortisol secretion...
  82. ncbi request reprint Psychiatric symptoms and cognitive dysfunction caused by Epstein-Barr virus-induced encephalitis
    Joachim Behr
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, 10117 Berlin, Germany
    Eur Psychiatry 21:521-2. 2006
    ..Clinical recovery and clearance of cerebrospinal fluid EBV DNA appeared following ganciclovir treatment within 6 weeks...
  83. ncbi request reprint Anxiety modulation by the heart? Aerobic exercise and atrial natriuretic peptide
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Psychoneuroendocrinology 31:1127-30. 2006
    ..Our results suggest that besides other mechanisms, ANP might be a physiologically relevant humoral link between the heart and anxiety-related behavior contributing to the acute anxiolytic effects of exercise...
  84. doi request reprint Novelty seeking modulates medial prefrontal activity during the anticipation of emotional stimuli
    Felix Bermpohl
    Berenson Allen Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Psychiatry Res 164:81-5. 2008
    ..BOLD responses to emotional expectancy were positively correlated with novelty-seeking scores in the medial prefrontal cortex. This correlation was strongest for the sub-dimension of exploratory excitability...
  85. ncbi request reprint Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Shumannstrasse 20 21, 10117 Berlin, Germany
    Neuropsychopharmacology 32:2098-107. 2007
    ..Our findings further suggest that CB1 receptor antagonism may be involved in restoring disturbed interactions between the activity of the endocannabinoid system and glutamate neurotransmitter system implied in schizophrenia...
  86. ncbi request reprint Brain activation elicited by affectively positive stimuli is associated with a lower risk of relapse in detoxified alcoholic subjects
    Andreas Heinz
    Department of Psychiatry, Charite University Medical Center Berlin, CCM, Berlin, Germany
    Alcohol Clin Exp Res 31:1138-47. 2007
    ..We assessed whether brain activation elicited by (1) alcohol associated, (2) affectively positive, and (3) negative versus neutral stimuli is associated with the subsequent risk of relapse...
  87. ncbi request reprint Hepatitis C treatment in "difficult-to-treat" psychiatric patients with pegylated interferon-alpha and ribavirin: response and psychiatric side effects
    Martin Schaefer
    Charite Universitatsmedizin Berlin, Klinik und Poliklinik für Psychiatrie und Psychotherapie Campus Charité Mitte, Berlin, Germany
    Hepatology 46:991-8. 2007
    ....
  88. ncbi request reprint Genetic research with intermediate phenotypes: phenocopies, perspectives and pitfalls
    Andreas Heinz
    Department of Psychiatry and Psychotherapy, Charite University Medical Center Berlin, Charite Campus Mitte, Berlin, Germany
    Addiction 102:1696-7. 2007
  89. ncbi request reprint The effects of catechol O-methyltransferase genotype on brain activation elicited by affective stimuli and cognitive tasks
    Andreas Heinz
    Department of Psychiatry, Charite University Medical Center, Campus Mitte, Berlin, Germany
    Rev Neurosci 17:359-67. 2006
    ..Thus the met158 allele seems to be beneficial during the performance of working memory and attention-related tasks, whereas the val158 allele appears to be advantageous during the processing of aversive emotional stimuli...
  90. ncbi request reprint Therapy and supportive care of alcoholics: guidelines for practitioners
    Thorsten Kienast
    Department of Psychiatry, Charite, University Medical Center, Campus Mitte, Berlin, Germany
    Dig Dis 23:304-9. 2005
    ..Moreover, the concept can be quickly and easily integrated into the daily routine of any therapeutic team...
  91. ncbi request reprint Therapy and supportive care of alcoholics: guidelines for practitioners
    Andreas Heinz
    Department of Psychiatry of the Charité, Humboldt University Berlin, Schumannstrasse 20 21, Berlin 10117, Germany
    Best Pract Res Clin Gastroenterol 17:695-708. 2003
    ..If adequate treatment is available, relapse rates were as low as 50% in those follow-up studies that examined treatment periods of up to 2 years, so that there is no justification for therapeutic nihilism...
  92. ncbi request reprint Lithium augmentation therapy in refractory depression: clinical evidence and neurobiological mechanisms
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Hospital, Humboldt University at Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Can J Psychiatry 48:440-8. 2003
    ..It also examines hypotheses on the mode of action of lithium augmentation, with a focus on serotonin (5-HT) and neuroendocrine systems, and proposes recommendations for future research...
  93. ncbi request reprint Pharmacogenetic insights to monoaminergic dysfunction in alcohol dependence
    Andreas Heinz
    Department of Psychiatry, Campus Charite Mitte, Charite University Medicine Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Psychopharmacology (Berl) 174:561-70. 2004
    ..The severity and time-course of recovery of these neuroadaptive changes may depend on the genetic constitution of monoamine transporters and receptors and contribute to the relapse risk of alcoholics...
  94. ncbi request reprint Treatment of chronic hepatitis C in patients with drug dependence: time to change the rules?
    Martin Schaefer
    Department of Psychiatry CCM, Charite University Medicine Berlin, Berlin, Germany
    Addiction 99:1167-75. 2004
    ....
  95. ncbi request reprint [Genetic and pharmacological effects on prefrontal cortical function in schizophrenia]
    Andreas Heinz
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Berlin
    Nervenarzt 75:845-56. 2004
    ..Molecular brain imaging combines imaging techniques with the assessment of genotype effects and represents a powerful tool for the understanding of neuropsychiatric disorders...
  96. ncbi request reprint Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter
    Andreas Heinz
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, 10117 Berlin, Germany
    Nat Neurosci 8:20-1. 2005
    ..s carriers also showed greater coupling between the amygdala and the ventromedial prefrontal cortex, which may contribute to the abnormally high activity in the amygdala and medial prefrontal cortex seen in major depression...
  97. ncbi request reprint Immigration-associated variables and substance dependence
    Sabine M Grüsser
    Institute for Medical Psychology, Center for Humanities and Health Sciences, Charite University Medicine Berlin, Tucholskystrasse 2, 10117 Berlin, Germany
    J Stud Alcohol 66:98-104. 2005
    ....
  98. ncbi request reprint Is dose escalation of antidepressants a rational strategy after a medium-dose treatment has failed? A systematic review
    Mazda Adli
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Germany
    Eur Arch Psychiatry Clin Neurosci 255:387-400. 2005
    ..e. augmentation or change of compound) are lacking. The aim of this publication is to review available direct and indirect evidence concerning dose increase of antidepressants after a medium-dose trial has failed...
  99. ncbi request reprint Prevention of interferon-alpha associated depression in psychiatric risk patients with chronic hepatitis C
    Martin Schaefer
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    J Hepatol 42:793-8. 2005
    ..We prospectively studied the efficacy of a pre-emptive treatment with the antidepressant citalopram to prevent depression during hepatitis C treatment with pegylated IFN-alpha-2b plus ribavirin...
  100. ncbi request reprint The acute antipanic activity of aerobic exercise
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite University Medicine Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Am J Psychiatry 162:2376-8. 2005
    ..Regular physical activity is anxiolytic for both healthy subjects and patients with panic disorder. However, the acute antipanic activity of exercise has not yet been studied systematically...
  101. doi request reprint [Psychotherapy with traumatised migrants from Turkey: taking into account cultural factors]
    Meryam Schouler-Ocak
    Psychiatrische Universitätsklinik der Charité im St Hedwig Krankenhaus, Grosse Hamburger Strasse 5 11, 10115 Berlin, Germany
    Psychother Psychosom Med Psychol 58:169-75. 2008
    ..The influence of culture-specific factors on trauma-focussed psychotherapy is being discussed...